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Rheumatology / Original Article
Association between oral health and hyperuricemia in Korean adults: Korea National Health and Nutrition Examination Survey 2016–2019
Junyong Park, Minkook Son, Sung Won Lee, Won Tae Chung, Sang Yeob Lee
Korean J Intern Med. 2024;39(6):1001-1010. Published online October 22, 2024
Background/Aims: Hyperuricemia plays an essential role in the gout. Despite the clinical significance of hyperuricemia, a direct relationship between oral health and hyperuricemia has not been established. We aim to investigate the association between oral health and hyperuricemia.
Methods: We sele..
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Rheumatology / Original Article
Assessment of small fiber neuropathy and distal sensory neuropathy in female patients with fibromyalgia
Hong Ki Min, Sun Im, Geun-Young Park, Su-Jin Moon
Korean J Intern Med. 2024;39(6):989-1000. Published online October 29, 2024
Background/Aims: We investigated sudomotor dysfunction, small fiber neuropathy (SFN), and their clinical significance in female fibromyalgia patients.
Methods: Fibromyalgia patients and healthy controls (HCs) were recruited. Clinical and laboratory data were measured. Electrochemical skin conductan..
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Infectious diseases / Original Article
Adverse drug reactions following treatment of latent tuberculosis infection: a linked national tuberculosis surveillance with claims database
Yu-Seon Jung, Sun-Young Jung, Jae-Eun Lee, Kyungeun Lee, Jae Chol Choi
Korean J Intern Med. 2024;39(6):979-988. Published online October 22, 2024
Background/Aims: Few real-world studies explored factors associated with latent tuberculosis infection (LTBI) treatment-related adverse drug reactions (ADRs). This study evaluate ADRs that lead to the discontinuation of LTBI treatment and identify the associated factors, including age groups and dru..
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Nephrology / Original Article
Kidney replacement therapy trends in end-stage kidney disease patients in South Korea during the COVID-19 pandemic
Ah-Young Kim, Min-Jeong Lee, Heejung Choi, Hankil Lee, Inwhee Park
Korean J Intern Med. 2024;39(6):967-978. Published online October 24, 2024
Background/Aims: The corona virus disease 2019 posed a major risk for end-stage kidney disease (ESKD) cases. Our study aimed to assess changes in kidney replacement therapy (KRT) trends and healthcare access for these patients during the pandemic.
Methods: We retrospectively analyzed nationwide dat..
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Pulmonology / Original Article
Short-term and long-term outcomes of critically ill patients with solid malignancy: a retrospective cohort study
Su Yeon Lee, Jin Won Huh, Sang-Bum Hong, Chae-Man Lim, Jee Hwan Ahn
Korean J Intern Med. 2024;39(6):957-966. Published online October 22, 2024
Background/Aims: With the global increase in patients with solid malignancies, it is helpful to understand the outcomes of intensive care unit (ICU) admission for these patients. This study evaluated the risk factors for ICU mortality and the shortand long-term outcomes in patients with solid malign..
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Cardiology / Original Article
Impact of discharge checklist on guideline-directed medical therapy and mid-term prognosis in heart failure
Won-Seok Lee, Kyu-Sun Lee, Helsi Rismiati, Hae-Young Lee
Korean J Intern Med. 2024;39(6):945-956. Published online October 24, 2024
Background/Aims: Despite the proven benefit of the guideline-directed medical therapy (GDMT), it remains underutilized in patients hospitalized with acute heart failure (HF). We aimed to evaluate the impact of the discharge checklist on GDMT installation and the prognosis of HF patients.
Methods: T..
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Gastroenterology / Original Article
Evolving epidemiology of non-alcoholic fatty liver disease in South Korea: incidence, prevalence, progression, and healthcare implications from 2010 to 2022
Jae Woo Park, Jeong-Ju Yoo, Dong Hyeon Lee, Young Chang, Hoongil Jo, Young Youn Cho, Sangheun Lee, Log Young Kim, Jae Young Jang; the Korean Association for the Study of the Liver
Korean J Intern Med. 2024;39(6):931-944. Published online October 24, 2024
Background/Aims: Non-alcoholic fatty liver disease (NAFLD), now the most common chronic liver worldwide, has become a significant public health concern. This study aims to analyze the evolving epidemiology of NAFLD in South Korea.
Methods: We utilized claim data from the Korean National Health Insu..
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Gastroenterology / Original Article
The role of PD-1/PD-L1 pathway in ulcerative colitis and changes following tonsil-derived mesenchymal stem cells treatment
Eun Mi Song, Yang Hee Joo, Sung-Ae Jung, Ju-Ran Byeon, A-Reum Choe, Yehyun Park, Chung Hyun Tae, Chang Mo Moon, Seong-Eun Kim, Hye-Kyung Jung, Ki-Nam Shim
Korean J Intern Med. 2024;39(6):917-930. Published online November 1, 2024
Background/Aims: The programmed death 1 (PD-1)/programmed death-ligand 1 (PD-L1) pathway has not been fully evaluated in inflammatory bowel disease. We evaluated PD-1/PD-L1 levels in patients with ulcerative colitis (UC) and their significance in tonsil-derived mesenchymal stem cells (TMSCs) treatme..
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Gastroenterology / Original Article
Tight junction protein changes in irritable bowel syndrome: the relation of age and disease severity
Sang Un Kim, Ji A Choi, Man-Hoon Han, Jin Young Choi, Ji Hye Park, Moon Sik Kim, Yong Hwan Kwon
Korean J Intern Med. 2024;39(6):906-916. Published online November 1, 2024
Background/Aims: The etiology of irritable bowel syndrome (IBS) is associated with intestinal mucosal barrier damage. However, changes in the tight junction (TJ) proteins in IBS have not been fully elucidated. This study aimed to evaluate TJ protein changes in IBS patients and the relationship betwe..
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Nephrology / Review
Steps to understanding diabetes kidney disease: a focus on metabolomics
Hyo Jin Kim, Sang Heon Song
Korean J Intern Med. 2024;39(6):898-905. Published online October 22, 2024
Diabetic nephropathy (DN), a leading cause of chronic kidney disease and end-stage kidney disease (ESKD), poses global health challenges given its increasing prevalence. DN increases the risk of mortality and cardiovascular events. Early identification and appropriate DN management are crucial. Howe..
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Nephrology / Review
Machine learning approaches toward an understanding of acute kidney injury: current trends and future directions
Inyong Jeong, Nam-Jun Cho, Se-Jin Ahn, Hwamin Lee, Hyo-Wook Gil
Korean J Intern Med. 2024;39(6):882-897. Published online October 29, 2024
Acute kidney injury (AKI) is a significant health challenge associated with adverse patient outcomes and substantial economic burdens. Many authors have sought to prevent and predict AKI. Here, we comprehensively review recent advances in the use of artificial intelligence (AI) to predict AKI, and t..
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Nephrology / Review
Kidney transplantation in the elderly
Byung Hwa Park, Song Yi Kil, Ye Na Kim, Ho Sik Shin, Yeonsoon Jung, Hark Rim
Korean J Intern Med. 2024;39(6):875-881. Published online October 24, 2024
Interest in kidney transplant studies in the elderly population is increasing as more research has been conducted on the immune system. With this review, we hope to encourage the need for research on kidney transplantation in the elderly.
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Nephrology / Editorial
Impact of COVID-19 on end-stage kidney disease incidence and clinical practice
Hayne Cho Park, Young-Ki Lee
Korean J Intern Med. 2024;39(6):872-874. Published online November 1, 2024
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Gastroenterology / Image of interest
A case of esophagogastric junctional outlet obstruction caused by thoracic aortic aneurysm
Jin Ook Jang, Tae Un Kim, Hwaseong Ryu, Byung-Soo Park, Su Jin Kim
Korean J Intern Med. 2024;39(5):867-868. Published online May 22, 2024
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Gastroenterology / Image of interest
Acute pancreatitis by huge gastric phytobezoar
Dong-Ge Han, Yi-Xue Zhou, Wei Liu
Korean J Intern Med. 2024;39(5):865-866. Published online May 27, 2024
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Rheumatology / Original Article
Effect of abatacept versus conventional synthetic disease modifying anti-rheumatic drugs on rheumatoid arthritis-associated interstitial lung disease
Kyung-Ann Lee, Bo Young Kim, Sung Soo Kim, Yun Hong Cheon, Sang-Il Lee, Sang-Hyon Kim, Jae Hyun Jung, Geun-Tae Kim, Jin-Wuk Hur, Myeung-Su Lee, Yun Sung Kim, Seung-Jae Hong, Suyeon Park, Hyun-Sook Kim
Korean J Intern Med. 2024;39(5):855-864. Published online August 30, 2024
Background/Aims: To compare the effects of abatacept and conventional synthetic disease modifying anti-rheumatic drugs (csDMARDs) on the progression and development of rheumatoid arthritis-associated interstitial lung disease (RA-ILD).
Methods: This multi-center retrospective study included RA pati..
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Rheumatology / Original Article
High vegetable consumption and regular exercise are associated with better quality of life in patients with gout
Hyunsue Do, Hyo Jin Choi, Byoongyong Choi, Chang-Nam Son, Sang-Hyon Kim, You-Jung Ha, Ji Hyoun Kim, Min Jung Kim, Kichul Shin, Hyun-Ok Kim, Ran Song, Sung Won Lee, Joong Kyong Ahn, Seung-Geun Lee, Chang Hoon Lee, Kyeong Min Son, Ki Won Moon
Korean J Intern Med. 2024;39(5):845-854. Published online June 24, 2024
Background/Aims: The Gout Impact Scale (GIS), a part of the Gout Assessment Questionnaire 2.0, is used to measure gout-specific health-related quality of life (HRQOL). Although several studies have been conducted on the factors affecting the HRQOL of patients with gout, few have focused on lifestyle..
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Rheumatology / Original Article
Drug retention of biologic and targeted synthetic disease-modifying antirheumatic drugs in Korean patients with seropositive rheumatoid arthritis
Bong-Woo Lee, Jennifer Jooha Lee, Wan-Uk Kim
Korean J Intern Med. 2024;39(5):833-844. Published online May 27, 2024
Background/Aims: The aim of this study was to compare the short- and long-term retention rates of biologic and targeted synthetic disease-modifying anti-rheumatic drugs (b/tsDMARDs) in Korean patients with seropositive rheumatoid arthritis.
Methods: This study was conducted with 1,538 treatment cou..
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Infectious diseases / Original Article
Clinical effects of non-pharmaceutical interventions for COVID-19 on other nationally notifiable infectious diseases in South Korea
Hyun-Jin Lee, Beom Seuk Hwang, Seong Ho Im, Seog-Kyun Mun, Munyoung Chang
Korean J Intern Med. 2024;39(5):823-832. Published online August 13, 2024
Background/Aims: This study aimed to assess the impact of non-pharmaceutical interventions (NPIs) implemented during the COVID-19 pandemic on nationally notifiable infectious diseases (NNIDs) in South Korea.
Methods: Long-term data on seven NNIDs from 2018 to 2021 were analyzed to identify trends a..
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