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Pulmonology
Risk factors for progressing to critical illness in patients with hospital-acquired COVID-19
Kyung-Eui Lee, Jinwoo Lee, Sang-Min Lee, Hong Yeul Lee
Korean J Intern Med. 2024;39(3):477-487. Published online April 18, 2024
Background/Aims: Risk factors for progression to critical illness in hospital-acquired coronavirus disease 2019 (COVID-19) remain unknown. Here, we assessed the incidence and risk factors for progression to critical illness and determined their effects on clinical outcomes in patients with hospital-..
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Cardiology
Impact of an expanded reimbursement policy on utilization of implantable loop recorders in patients with cryptogenic stroke in Korea
Hye Bin Gwag, Nak Gyeong Ko, Mihyeon Jin
Korean J Intern Med. 2024;39(3):469-476. Published online April 18, 2024
Background/Aims: The reimbursement policy for cryptogenic stroke (CS) was expanded in November 2018 from recurrent strokes to the first stroke episode. No reports have demonstrated whether this policy change has affected trends in implantable loop recorder (ILR) utilization.
Methods: We identified ..
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Modified application of SAMe-TT2R2 scoring system in Asian patients with atrial fibrillation for the selection of oral anticoagulants
Seong Won Jeon, Nuri Lee, Ki Hong Lee, Minjeong Ha, Changhyun Kim, Yoo Ri Kim, Nam Sik Yoon, Hyung Wook Park
Korean J Intern Med. 2024;39(3):458-468. Published online January 30, 2024
Background/Aims: The SAMe-TT2R2 score is used for assessing anticoagulation control (AC) quality with warfarin. However, it is hard to apply SAMe-TT2R2 score in Asian patients with atrial fibrillation (AF), because it has not been proven in those populatio..
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Gastroenterology
Prevalence and predictors of multidrug-resistant bacteremia in liver cirrhosis
Aryoung Kim, Byeong Geun Song, Wonseok Kang, Dong Hyun Sinn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Myung Ji Goh
Korean J Intern Med. 2024;39(3):448-457. Published online April 30, 2024
Background/Aims: Improved knowledge of local epidemiology and predicting risk factors of multidrug-resistant (MDR) bacteria are required to optimize the management of infections. This study examined local epidemiology and antibiotic resistance patterns of liver cirrhosis (LC) patients and evaluated ..
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Predicting Helicobacter pylori infection from endoscopic features
Jun-young Seo, Ji Yong Ahn, Seonok Kim, Hee Kyong Na, Jeong Hoon Lee, Kee Wook Jung, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung
Korean J Intern Med. 2024;39(3):439-447. Published online April 30, 2024
Background: Helicobacter pylori infection, prevalent in more than half of the global population, is associated with various gastrointestinal diseases, including peptic ulcers and gastric cancer. The effectiveness of early diagnosis and treatment in preventing gastric cancer highlights the nee..
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Self-screening questionnaire for perianal fistulizing disease in patients with Crohn’s disease
O Seong Kweon, Ben Kang, Yoo Jin Lee, Eun Soo Kim, Sung Kook Kim, Hyun Seok Lee, Yun Jin Chung, Kyeong Ok Kim, Byung Ik Jang; on behalf of Crohn’s Colitis Association in Daegu-Gyeongbuk (CCAiD)
Korean J Intern Med. 2024;39(3):430-438. Published online April 5, 2024
Background/Aims: A poor prognostic factor for Crohn’s disease (CD) includes perianal fistulizing disease, including perianal fistula and/or perianal abscess. Currently, a tool to assess perianal symptoms in patients with CD remains nonexistent. This study aimed to develop a perianal fistulizing di..
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Role of biomarkers in antimicrobial stewardship: physicians’ perspectives
Hyeri Seok, Dae Won Park
Korean J Intern Med. 2024;39(3):413-429. Published online April 30, 2024
Biomarkers are playing an increasingly important role in antimicrobial stewardship. Their applications have included use in algorithms that evaluate suspected bacterial infections or provide guidance on when to start or stop antibiotic therapy, or when therapy should be repeated over a short period ..
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Implementing antimicrobial stewardship: lessons and perspectives from a university-affiliated tertiary hospital in Korea
Soo Jin Lee, Raeseok Lee, Sung-Yeon Cho, Dukhee Nho, Hye Lim Ahn, Dong-Gun Lee
Korean J Intern Med. 2024;39(3):399-412. Published online April 30, 2024
Antimicrobial stewardship programs (ASPs) can lower antibiotic use, decrease medical expenses, prevent the emergence of resistant bacteria, and enhance treatment for infectious diseases. This study summarizes the stepwise implementation and effects of ASPs in a single university-affiliated tertiary ..
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Quantitative and qualitative evaluation of antimicrobial usage: the first step for antimicrobial stewardship
Song Mi Moon, Bongyoung Kim, Hong Bin Kim
Korean J Intern Med. 2024;39(3):383-398. Published online April 30, 2024
The identification of antimicrobial use patterns is essential for determining key targets for antimicrobial stewardship interventions and evaluating the effectiveness thereof. Accurately identifying antimicrobial use patterns requires quantitative evaluation, which focuses on measuring the quantity ..
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Principles and practices of antimicrobial stewardship programs in Korea
Ki Tae Kwon, Shin-Woo Kim
Korean J Intern Med. 2024;39(3):373-382. Published online April 23, 2024
This review addresses the escalating challenge posed by antibiotic resistance, highlighting its profound impact on global public health, including increased mortality rates and healthcare expenditures. The review focuses on the need to adopt the One Health approach to effectively manage antibiotic us..
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A novel strategy for predicting critical illness in hospital-acquired COVID-19
Woo Hyun Cho
Korean J Intern Med. 2024;39(3):371-372. Published online April 30, 2024
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Decompensated cirrhosis and antibiotic prophylaxis: striking a delicate balance
Jung Gil Park
Korean J Intern Med. 2024;39(3):369-370. Published online April 30, 2024
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Pregabalin-induced rhabdomyolysis in hemodialysis patient
Dong Eon Kim, Sang Heon Song
Korean J Intern Med. 2024;39(2):366-367. Published online November 30, 2023
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Migration of central vein stent into the right atrium
Kyoung-Woo Seo, Jin-Sun Park
Korean J Intern Med. 2024;39(2):364-365. Published online November 10, 2023
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The significance of ophthalmologic examination in a patient with xanthoma
In Sun Goak, Seol A Jang, Yu Jin Jin, In-Cheon You, Ji Hyun Park
Korean J Intern Med. 2024;39(2):362-363. Published online December 22, 2023
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Duration of corticosteroid treatment in hospitalized COVID-19 patients, less is more
Marko Lucijanic, Ivan Papic, Maja Ortner Hadziabdic
Korean J Intern Med. 2024;39(2):360-361. Published online February 6, 2024
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Rheumatology
Predictors of renal relapse in Koreans with lupus nephritis after achieving complete response: a 35-years of experience at a single center
Howook Jeon, Jennifer Lee, Su-Jin Moon, Seung-Ki Kwok, Ji Hyeon Ju, Wan-Uk Kim, Sung-Hwan Park
Korean J Intern Med. 2024;39(2):347-359. Published online January 22, 2024
Background/Aims: Renal relapse has known to be a poor prognostic factor in patients with lupus nephritis (LN), but there were few studies that identified the risk factors of renal relapse in real world. We conducted this study based on 35-years of experience at a single center to find out predictors..
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Effect of belimumab in patients with systemic lupus erythematosus treated with low dose or no corticosteroids
Yeo-Jin Lee, Soo Min Ahn, Seokchan Hong, Ji-Seon Oh, Chang-Keun Lee, Bin Yoo, Yong-Gil Kim
Korean J Intern Med. 2024;39(2):338-346. Published online November 30, 2023
Background/Aims: Systemic lupus erythematosus (SLE) responder index (SRI)-4 response has been achieved with belimumab treatment in patients with moderate disease activity in cornerstone clinical trials and following studies. However, most studies involved patients treated with a mean prednisolone-eq..
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Hemato-oncology
Prognostic Significance Of Sequential 18f-fdg Pet/Ct During Frontline Treatment Of Peripheral T Cell Lymphomas
Ga-Young Song, Sung-Hoon Jung, Seo-Yeon Ahn, Mihee Kim, Jae-Sook Ahn, Je-Jung Lee, Hyeoung-Joon Kim, Jang Bae Moon, Su Woong Yoo, Seong Young Kwon, Jung-Joon Min, Hee-Seung Bom, Sae-Ryung Kang, Deok-Hwan Yang
Korean J Intern Med. 2024;39(2):327-337. Published online January 25, 2024
Background/Aims: The prognostic significance of 18F-fluorodeoxyglucose (FDG)-positron emission tomography-computed tomography (PET/CT) in peripheral T-cell lymphomas (PTCLs) are controversial. We explored the prognostic impact of sequential 18F-FDG PET/CT during frontline chemo..
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Pulmonology
Clinical impact of pleural fluid carcinoembryonic antigen on therapeutic strategy and efficacy in lung adenocarcinoma patients with malignant pleural effusion
Jaehee Lee, Deok Heon Lee, Ji Eun Park, Yong Hoon Lee, Sun Ha Choi, Hyewon Seo, Seung Soo Yoo, Shin Yup Lee, Seung-Ick Cha, Jae Yong Park, Chang Ho Kim
Korean J Intern Med. 2024;39(2):318-326. Published online February 14, 2024
Background/Aims: Epidermal growth factor receptor (EGFR) mutation is important in determining the treatment strategy for advanced lung cancer patients with malignant pleural effusion (MPE). Contrary to serum carcinoembryonic antigen (S-CEA) levels, the associations between pleural fluid CEA (PF-CEA)..
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