Cardiology / Original Article Sex-specific impact of the COVID-19 outbreak on the incidence of metabolic syndrome: a comparative study of 2018–2019 and 2020–2021 Kyeong-Hyeon Chun, Hyun-Jin Kim, Dae Ryong Kang, Jang Young Kim, Wonjin Kim, Yong Whi Jeong, Seung Hwan Han, Kwang Kon Koh; on behalf of the Taskforce Team of the Metabolic Syndrome Fact Sheet of the Korean Society of Cardiometabolic Syndrome Korean J Intern Med. 2025;40(2):262-274.   Published online March 1, 2025 DOI: https://doi.org/10.3904/kjim.2024.288              Crossref 1                      Background/Aims: The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted global health, exacerbated metabolic health issues, and altered lifestyle behaviors. This study examined the sex-specific impact of the COVID-19 outbreak on the incidence of metabolic syndrome using data fro..

Cardiology / Original Article Explainable paroxysmal atrial fibrillation diagnosis using an artificial intelligence-enabled electrocardiogram Yeongbong Jin, Bonggyun Ko, Woojin Chang, Kang-Ho Choi, Ki Hong Lee Korean J Intern Med. 2025;40(2):251-261.   Published online February 21, 2025 DOI: https://doi.org/10.3904/kjim.2024.130                 Background/Aims: Atrial fibrillation (AF) significantly contributes to global morbidity and mortality. Paroxysmal atrial fibrillation (PAF) is particularly common among patients with cryptogenic strokes or transient ischemic attacks and has a silent nature. This study aims to develop reliable artifi..

Cardiology / Review Sex differences in diagnosis and treatment of heart failure: toward precision medicine Soo Yong Lee, Seong-Mi Park Korean J Intern Med. 2025;40(2):196-207.   Published online March 1, 2025 DOI: https://doi.org/10.3904/kjim.2024.338                 There are sex-related differences in the pathophysiology and phenotype of heart failure (HF) as well as the pharmacokinetics and pharmacodynamics of drugs between women and men due to biological differences, such as heart and vessel size, response to blood volume and pressure, body water and muscle ..

Cardiology / Editorial Pandemics extend beyond infectious diseases: the emerging threat of non-communicable diseases Moojun Kim, Chan Joo Lee Korean J Intern Med. 2025;40(2):168-169.   Published online March 1, 2025 DOI: https://doi.org/10.3904/kjim.2025.046

Cardiology / Review Screening and diagnosis of atrial fibrillation using wearable devices Yoon Jung Park, Myung Hwan Bae Korean J Intern Med. 2025;40(1):7-14.   Published online May 3, 2024 DOI: https://doi.org/10.3904/kjim.2023.521              Web of Science 1    Crossref 1                 In recent years, the development and use of various devices for the screening of atrial fibrillation (AF) have significantly increased. Such devices include 12-lead electrocardiogram (ECG), photoplethysmography systems, and single-lead ECG and ECG patches. This review outlines several studies that h..

Cardiology / Original Article Predictive value and optimal cut-off level of high-sensitivity troponin T in patients with acute pulmonary embolism Moojun Kim, Chang-Ok Seo, Yong-Lee Kim, Hangyul Kim, Hye Ree Kim, Yun Ho Cho, Jeong Yoon Jang, Jong-Hwa Ahn, Min Gyu Kang, Kyehwan Kim, Jin-Sin Koh, Seok-Jae Hwang, Jin Yong Hwang, Jeong Rang Park Korean J Intern Med. 2025;40(1):65-77.   Published online January 1, 2025 DOI: https://doi.org/10.3904/kjim.2024.131                      Background/Aims: Elevated troponin levels predict in-hospital mortality and influence decisions regarding thrombolytic therapy in patients with acute pulmonary embolism (PE). However, the usefulness of high-sensitivity troponin T (hsTnT) regarding PE remains uncertain. We aimed to establish the opti..

Cardiology / Image of interest Femoral veno-arterial extracorporeal membrane oxygenation with a novel biatrial cannula for venous drainage and left ventricular venting Jun Hwan Cho, Woosik Han, Eun Jeong Cho, Sang-Yeub Lee, Sang-Wook Kim Korean J Intern Med. 2025;40(1):160-161.   Published online December 18, 2024 DOI: https://doi.org/10.3904/kjim.2024.046

Cardiology / Review Current status of modifiable risk factors for cardiovascular disease in Korean women In-Jeong Cho, Mi-Seung Shin Korean J Intern Med. 2025;40(1):15-23.   Published online October 22, 2024 DOI: https://doi.org/10.3904/kjim.2024.077                 Hypertension, diabetes mellitus, dyslipidemia, obesity, and smoking are the primary modifiable risk factors contributing to the increasing morbidity and mortality rates from cardiovascular disease (CVD) among Korean women. Significant sex-related differences exist in the prevalence, awareness, treat..

Cardiology / Original Article Impact of discharge checklist on guideline-directed medical therapy and mid-term prognosis in heart failure Won-Seok Lee, Kyu-Sun Lee, Helsi Rismiati, Hae-Young Lee Korean J Intern Med. 2024;39(6):945-956.   Published online October 24, 2024 DOI: https://doi.org/10.3904/kjim.2024.088                      Background/Aims: Despite the proven benefit of the guideline-directed medical therapy (GDMT), it remains underutilized in patients hospitalized with acute heart failure (HF). We aimed to evaluate the impact of the discharge checklist on GDMT installation and the prognosis of HF patients. Methods: T..

Cardiology / Image of interest Systemic venous air embolism after percutaneous lung biopsy Min Kyung Jung, Shin Young Kim, Jeong Min Ko Korean J Intern Med. 2024;39(6):1021-1022.   Published online August 13, 2024 DOI: https://doi.org/10.3904/kjim.2024.114

Cardiology / Original Article Efficacy of single-dose evolocumab injection in early-phase acute myocardial infarction: a retrospective single-center study Yongcheol Kim, Ji Woong Roh, Oh-Hyun Lee, Seok-Jae Heo, Eui Im, Deok-Kyu Cho, Byeong-Keuk Kim Korean J Intern Med. 2024;39(5):793-800.   Published online June 24, 2024 DOI: https://doi.org/10.3904/kjim.2024.080              Web of Science 1    Crossref 1                      Background/Aims: Achieving rapid reduction of low-density lipoprotein cholesterol (LDL-C) levels below 55 mg/dL in patients with acute myocardial infarction (AMI) can be challenging with statins alone. This single-center, retrospective study aimed to assess the impact of single-dose injection of evo..

Cardiology / Review 2024 KSoLA consensus on secondary dyslipidemia Hoyoun Won, Jae Hyun Bae, Hyunjung Lim, Minji Kang, Minjoo Kim, Sang-Hak Lee; on behalf of the Clinical Practice Guidelines Committee, Korean Society of Lipid and Atherosclerosis (KSoLA) Korean J Intern Med. 2024;39(5):717-730.   Published online August 30, 2024 DOI: https://doi.org/10.3904/kjim.2024.156              Web of Science 1    Crossref 1                 Elevated blood cholesterol and triglyceride levels induced by secondary causes are frequently observed. The identification and appropriate handling of these causes are essential for secondary dyslipidemia treatment. Major secondary causes of hypercholesterolemia and hypertriglyceridemia include an u..

Cardiology / Review Current evidence for prognostic benefit of intravascular imaging-guided percutaneous coronary intervention in chronic total occlusion intervention David Hong, Sung Eun Kim, Seung Hun Lee, Seung-Jae Lee, Jong-Young Lee, Sang Min Kim, Sang Yeub Lee, Woochan Kwon, Ki Hong Choi, Taek Kyu Park, Jeong Hoon Yang, Young Bin Song, Seung-Hyuk Choi, Hyeon-Cheol Gwon, Joo-Yong Hahn, Joo Myung Lee; The RENOVATE-COMPLEX-PCI Investigators Korean J Intern Med. 2024;39(5):702-716.   Published online February 29, 2024 DOI: https://doi.org/10.3904/kjim.2023.420                 Although percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) has been increasing in recent years, CTO PCI is still one of the most challenging procedures with relatively higher rates of procedural complications and adverse clinical events after PCI. Due to the innate limitatio..

Cardiology / Original Article Estimated pulse wave velocity as a forefront indicator of developing metabolic syndrome in Korean adults Hyun-Jin Kim, Byung Sik Kim, Dong Wook Kim, Jeong-Hun Shin Korean J Intern Med. 2024;39(4):612-624.   Published online June 24, 2024 DOI: https://doi.org/10.3904/kjim.2024.015                      Background/Aims: The predictive value of the estimated pulse wave velocity (ePWV) for the development of metabolic syndrome has not yet been extensively explored. This study aimed to fill this gap by evaluating ePWV as a potential predictor of metabolic syndrome development in middle-aged Korean adu..

Cardiology / Original Article Impact of an expanded reimbursement policy on utilization of implantable loop recorders in patients with cryptogenic stroke in Korea Hye Bin Gwag, Nak Gyeong Ko, Mihyeon Jin Korean J Intern Med. 2024;39(3):469-476.   Published online April 18, 2024 DOI: https://doi.org/10.3904/kjim.2023.479              Web of Science 1    Crossref 1                      Background/Aims: The reimbursement policy for cryptogenic stroke (CS) was expanded in November 2018 from recurrent strokes to the first stroke episode. No reports have demonstrated whether this policy change has affected trends in implantable loop recorder (ILR) utilization. Methods: We identified ..

Cardiology / Original Article Modified application of SAMe-TT2R2 scoring system in Asian patients with atrial fibrillation for the selection of oral anticoagulants Seong Won Jeon, Nuri Lee, Ki Hong Lee, Minjeong Ha, Changhyun Kim, Yoo Ri Kim, Nam Sik Yoon, Hyung Wook Park Korean J Intern Med. 2024;39(3):458-468.   Published online January 30, 2024 DOI: https://doi.org/10.3904/kjim.2023.381                 Background/Aims: The SAMe-TT2R2 score is used for assessing anticoagulation control (AC) quality with warfarin. However, it is hard to apply SAMe-TT2R2 score in Asian patients with atrial fibrillation (AF), because it has not been proven in those populatio..

Cardiology / Image of interest The significance of ophthalmologic examination in a patient with xanthoma In Sun Goak, Seol A Jang, Yu Jin Jin, In-Cheon You, Ji Hyun Park Korean J Intern Med. 2024;39(2):362-363.   Published online December 22, 2023 DOI: https://doi.org/10.3904/kjim.2023.346

Cardiology / Original Article Association of epicardial adipose tissue with metabolic risk factors on cardiovascular outcomes: serial coronary computed tomography angiography study Sungjoon Park, Dong Eun Kim, Su Min Kim, JungMin Choi, Sang Joon Park, Hae-Young Lee, Eun Ju Chun Korean J Intern Med. 2024;39(2):283-294.   Published online February 14, 2024 DOI: https://doi.org/10.3904/kjim.2023.389              Web of Science 1    Crossref 1                      Background/Aims: Epicardial adipose tissue (EAT) shares pathophysiological properties with other visceral fats and potentially triggers local inflammation. However, the association of EAT with cardiovascular disease (CVD) is still debatable. The study aimed to observe the changes and associations in..

Cardiology / Original Article Metabolic syndrome awareness in the general Korean population: results from a nationwide survey Hyun-Jin Kim, Mi-Seung Shin, Kyung-Hee Kim, Mi-Hyang Jung, Dong-Hyuk Cho, Ju-Hee Lee, Kwang Kon Koh Korean J Intern Med. 2024;39(2):272-282.   Published online January 30, 2024 DOI: https://doi.org/10.3904/kjim.2023.363              Crossref 2                      Background/Aims: Metabolic syndrome (MetS) raises the risk of cardiovascular disease and type 2 diabetes. An awareness of MetS is vital for early detection and proactive management, which can mitigate the risks associated with MetS. Therefore, our study aimed to investigate the level of awareness of..

Cardiology / Review Nighttime administration of antihypertensive medication: a review of chronotherapy in hypertension Hyun-Jin Kim, Sang-Ho Jo Korean J Intern Med. 2024;39(2):205-214.   Published online November 16, 2023 DOI: https://doi.org/10.3904/kjim.2023.304              Web of Science 1    Crossref 2                 Hypertension remains a global health concern because of suboptimal blood pressure control despite advancements in antihypertensive treatments. Chronotherapy, defined as evening or bedtime administration of medication based on biological rhythms, is emerging as a potential strategy to improve blood p..