Gastroenterology / Original Article Association between acid-suppressive drugs and risk of psoriasis: retrospective study using Korean National Health Insurance Service-National Sample Cohort Ji Hyun Kim, Joon-hong Min, Young Woo Jo, Jae Woo Kwon, Young Her Korean J Intern Med. 2025;40(1):57-64.   Published online January 1, 2025 DOI: https://doi.org/10.3904/kjim.2024.096                 Background/Aims: Psoriasis is a common inflammatory skin disorder following non-specific triggers. Involvement of immune system is widely accepted for pathogenesis studies have demonstrated importance of gut microbiota in pathogenesis of inflammatory skin diseases. Proton pump inhibitor (PPI) and hi..

Gastroenterology / Original Article Incidence and risk factors of immune checkpoint inhibitor-induced colitis in Korean patients with cancer Tae Kyun Kim, Hyun Seok Lee, Eun Soo Kim Korean J Intern Med. 2025;40(1):49-56.   Published online January 1, 2025 DOI: https://doi.org/10.3904/kjim.2024.135              Crossref 1                 Background/Aims: Immune checkpoint inhibitors (ICIs) are effective in treating cancer. However, various immune-related adverse events (irAEs) have become prevalent, with ICI-induced colitis being the most common gastrointestinal irAE. Thus, we aimed to investigate the incidence and risk factors of I..

Gastroenterology / Editorial Who is at risk for immune checkpoint inhibitor-induced colitis among Korean patients? Ji Hyun Kim, Sung Chul Park Korean J Intern Med. 2025;40(1):3-4.   Published online January 1, 2025 DOI: https://doi.org/10.3904/kjim.2024.417

Gastroenterology / Original Article Evolving epidemiology of non-alcoholic fatty liver disease in South Korea: incidence, prevalence, progression, and healthcare implications from 2010 to 2022 Jae Woo Park, Jeong-Ju Yoo, Dong Hyeon Lee, Young Chang, Hoongil Jo, Young Youn Cho, Sangheun Lee, Log Young Kim, Jae Young Jang; the Korean Association for the Study of the Liver Korean J Intern Med. 2024;39(6):931-944.   Published online October 24, 2024 DOI: https://doi.org/10.3904/kjim.2024.164              Crossref 2                      Background/Aims: Non-alcoholic fatty liver disease (NAFLD), now the most common chronic liver worldwide, has become a significant public health concern. This study aims to analyze the evolving epidemiology of NAFLD in South Korea. Methods: We utilized claim data from the Korean National Health Insu..

Gastroenterology / Original Article The role of PD-1/PD-L1 pathway in ulcerative colitis and changes following tonsil-derived mesenchymal stem cells treatment Eun Mi Song, Yang Hee Joo, Sung-Ae Jung, Ju-Ran Byeon, A-Reum Choe, Yehyun Park, Chung Hyun Tae, Chang Mo Moon, Seong-Eun Kim, Hye-Kyung Jung, Ki-Nam Shim Korean J Intern Med. 2024;39(6):917-930.   Published online November 1, 2024 DOI: https://doi.org/10.3904/kjim.2024.019                      Background/Aims: The programmed death 1 (PD-1)/programmed death-ligand 1 (PD-L1) pathway has not been fully evaluated in inflammatory bowel disease. We evaluated PD-1/PD-L1 levels in patients with ulcerative colitis (UC) and their significance in tonsil-derived mesenchymal stem cells (TMSCs) treatme..

Gastroenterology / Original Article Tight junction protein changes in irritable bowel syndrome: the relation of age and disease severity Sang Un Kim, Ji A Choi, Man-Hoon Han, Jin Young Choi, Ji Hye Park, Moon Sik Kim, Yong Hwan Kwon Korean J Intern Med. 2024;39(6):906-916.   Published online November 1, 2024 DOI: https://doi.org/10.3904/kjim.2024.097                      Background/Aims: The etiology of irritable bowel syndrome (IBS) is associated with intestinal mucosal barrier damage. However, changes in the tight junction (TJ) proteins in IBS have not been fully elucidated. This study aimed to evaluate TJ protein changes in IBS patients and the relationship betwe..

Gastroenterology / Editorial Understanding the epidemiology of metabolic dysfunction-associated steatotic liver disease is essential for its management: need for attention to accurate diagnostic coding and classification Han Ah Lee Korean J Intern Med. 2024;39(6):869-871.   Published online November 1, 2024 DOI: https://doi.org/10.3904/kjim.2024.351

Gastroenterology / Image of interest A case of esophagogastric junctional outlet obstruction caused by thoracic aortic aneurysm Jin Ook Jang, Tae Un Kim, Hwaseong Ryu, Byung-Soo Park, Su Jin Kim Korean J Intern Med. 2024;39(5):867-868.   Published online May 22, 2024 DOI: https://doi.org/10.3904/kjim.2024.084

Gastroenterology / Image of interest Acute pancreatitis by huge gastric phytobezoar Dong-Ge Han, Yi-Xue Zhou, Wei Liu Korean J Intern Med. 2024;39(5):865-866.   Published online May 27, 2024 DOI: https://doi.org/10.3904/kjim.2024.056              Web of Science 1    Crossref 1

Gastroenterology / Original Article Perception of fecal microbiota transplantation in patients with ulcerative colitis in Korea: a KASID multicenter study Jebyung Park, Sung Noh Hong, Hong Sub Lee, Jongbeom Shin, Eun Hye Oh, Kwangwoo Nam, Gyeol Seong, Hyun Gun Kim, Jin-Oh Kim, Seong Ran Jeon; The Small Intestine Research Group and the Microbiome Research Group of the Korean Association for the Study of Intestinal Diseases (KASID) Korean J Intern Med. 2024;39(5):783-792.   Published online August 30, 2024 DOI: https://doi.org/10.3904/kjim.2024.053              Web of Science 2    Crossref 2                      Background/Aims: Fecal microbiota transplantation (FMT) is a promising therapy for inducing and maintaining remission in patients with ulcerative colitis (UC). However, FMT has not been approved for UC treatment in Korea. Our study aimed to investigate patient perceptions of FMT under the national m..

Gastroenterology / Original Article Prevalence and risk factors for gallstone and renal stone formation in patients with intestinal Behçet’s disease Jaewon Song, Soo Jung Park, Jae Jun Park, Tae Il Kim, Jihye Park, Jae Hee Cheon Korean J Intern Med. 2024;39(5):770-782.   Published online August 13, 2024 DOI: https://doi.org/10.3904/kjim.2024.006                      Background/Aims: The association between inflammatory bowel disease (IBD) and gallstone and renal stone formation has been established. However, few studies have investigated this association in patients with intestinal Behçet’s disease (BD). We aimed to examine the prevalence of gallstones and r..

Gastroenterology / Original Article Primary surgery versus pharmacotherapy for newly diagnosed ileocecal Crohn’s disease: a hospital-based cohort study Yehyun Park, Soo Jung Park, Tae Il Kim, Won Ho Kim, Jae Hee Cheon Korean J Intern Med. 2024;39(5):759-769.   Published online June 24, 2024 DOI: https://doi.org/10.3904/kjim.2023.542                      Background/Aims: Limited knowledge exists regarding the optimal timing and relative advantages of primary surgery compared to medical treatment in ileocecal Crohn’s disease (CD). This study aimed to compare long-term outcomes between medication-based treatment versus surgery in newly diagnosed ile..

Gastroenterology / Editorial Seeking acceptance: how education shifts views on fecal microbiota transplants for ulcerative colitis in Korea Jeongkuk Seo, Chang Hwan Choi Korean J Intern Med. 2024;39(5):697-699.   Published online August 30, 2024 DOI: https://doi.org/10.3904/kjim.2024.272

Gastroenterology / Image of interest A rare case of esophageal ulcer: esophageal tuberculosis Dong-Ge Han, Xiao-Xia Wang, Wei Liu Korean J Intern Med. 2024;39(4):691-692.   Published online April 9, 2024 DOI: https://doi.org/10.3904/kjim.2023.458

Gastroenterology / Original Article Clinical course of asymptomatic duodenal subepithelial lesions Seokin Kang, Kwangbeom Park, Do Hoon Kim, Yuri Kim, Hee Kyong Na, Jeong Hoon Lee, Ji Yong Ahn, Kee Wook Jung, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung Korean J Intern Med. 2024;39(4):603-611.   Published online June 13, 2024 DOI: https://doi.org/10.3904/kjim.2023.358                      Background/Aims: There is limited knowledge regarding the management of duodenal subepithelial lesions (SELs) owing to a lack of understanding of their natural course. This study aimed to assess the natural course of asymptomatic duodenal SELs and provide management recommendations. Methods: Patien..

Gastroenterology / Original Article Increasing correlation between oral and gastric microbiota during gastric carcinogenesis Hee Sang You, Jae Yong Park, Hochan Seo, Beom Jin Kim, Jae Gyu Kim Korean J Intern Med. 2024;39(4):590-602.   Published online June 24, 2024 DOI: https://doi.org/10.3904/kjim.2023.490              Crossref 1                      Background/Aims: Recent research has increasingly focused on the role of the gastric microbiome in the development of gastric cancer. We aimed to investigate the changes in the microbiome during gastric carcinogenesis in structural and functional aspects, with a specific focus on the association bet..

Gastroenterology / Original Article Efficacy comparison of high-genetic barrier nucleos(t)ide analogues in treatment-naïve chronic hepatitis B patients: a network meta-analysis Jaejun Lee, Ahlim Lee, Pil Soo Sung, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Hyun Yang Korean J Intern Med. 2024;39(4):577-589.   Published online June 13, 2024 DOI: https://doi.org/10.3904/kjim.2023.311                      Background/Aims: Four high-genetic barrier nucleos(t)ide analogues (NAs) for chronic hepatitis B (CHB), namely entecavir (ETV), tenofovir disoproxil fumarate (TDF), tenofovir alafenamide (TAF), and besifovir dipivoxil maleate (BSV), have been established. The aim of this study is to investigate the ..

Gastroenterology / Review Approaches and considerations in the endoscopic treatment of T1 colorectal cancer Yunho Jung Korean J Intern Med. 2024;39(4):563-576.   Published online May 14, 2024 DOI: https://doi.org/10.3904/kjim.2023.487                 The detection of early colorectal cancer (CRC) is increasing through the implementation of screening programs. This increased detection enhances the likelihood of minimally invasive surgery and significantly lowers the risk of recurrence, thereby improving patient survival and reducing mortality rat..

Gastroenterology / Review Artificial intelligence in colonoscopy: from detection to diagnosis Eun Sun Kim, Kwang-Sig Lee Korean J Intern Med. 2024;39(4):555-562.   Published online May 2, 2024 DOI: https://doi.org/10.3904/kjim.2023.332                 This study reviews the recent progress of artificial intelligence for colonoscopy from detection to diagnosis. The source of data was 27 original studies in PubMed. The search terms were “colonoscopy” (title) and “deep learning” (abstract). The eligibility criteria were: (1) the dependent varia..

Gastroenterology / Review Strategies to improve screening colonoscopy quality for the prevention of colorectal cancer Joo Hye Song, Eun Ran Kim Korean J Intern Med. 2024;39(4):547-554.   Published online January 22, 2024 DOI: https://doi.org/10.3904/kjim.2023.334              Web of Science 1    Crossref 1                 The incidence and mortality of colorectal cancer (CRC) have decreased through regular screening colonoscopy, surveillance, and endoscopic treatment. However, CRC can still be diagnosed after negative colonoscopy. Such CRC is called interval CRC and accounts for 1.8–9.0% of all CRC cases. Most case..