Gastroenterology / Original Article Prevalence of viral hepatitis A and C in patients with inflammatory bowel disease: a nationwide population-based study in South Korea Jin Hwa Park, Sang Hyoung Park, Sang Pyo Lee, Kang Nyeong Lee, Hang Lak Lee, Oh Young Lee, Soorack Ryu, Junwon Go Korean J Intern Med. 2026;41(1):95-106.   Published online January 1, 2026 DOI: https://doi.org/10.3904/kjim.2025.210       Background/Aims: We investigated whether patients with inflammatory bowel disease (IBD) in Korea have an increased risk of hepatitis A virus (HAV) and hepatitis C virus (HCV) infections and sought to identify the risk factors for these infections. Methods: We performed a nationwide population-based..

Gastroenterology / Original Article The effects of Helicobacter pylori eradication and development of immune-mediated disorder in children: a nationwide population-based study in Korea You Ie Kim, Joon Sung Kim, Sang Yong Kim, Byung-Wook Kim Korean J Intern Med. 2026;41(1):85-94.   Published online January 1, 2026 DOI: https://doi.org/10.3904/kjim.2024.065       Background/Aims: Helicobacter pylori may protect against immune-mediated disorders such as inflammatory bowel disease (IBD) and asthma. This study evaluated whether eradication was associated with IBD and asthma in Korean children. Methods: Data were collected from the Korean National Health..

Gastroenterology / Review Clinical management of gastric mucosa-associated lymphoid tissue lymphoma Ji Yong Ahn Korean J Intern Med. 2026;41(1):8-14.   Published online December 23, 2025 DOI: https://doi.org/10.3904/kjim.2024.143                 Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is often associated with chronic Helicobacter pylori infection. For an accurate diagnosis of gastric MALT lymphoma, clinical suspicion and careful endoscopic examination with multiple biopsies should be performed, and the final patholo..

Gastroenterology / Original Article Risk factors for bleeding from gastric antral vascular ectasia Sung Hyun Cho, Jinyoung Kim, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Kee Wook Jung, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung Korean J Intern Med. 2026;41(1):74-84.   Published online January 1, 2026 DOI: https://doi.org/10.3904/kjim.2024.380       Background/Aims: Gastric antral vascular ectasia (GAVE) is a rare but important cause of gastrointestinal (GI) bleeding. The clinical course of GAVE is not well-known, and recurrent bleeding from GAVE is a therapeutic challenge. Therefore, we investigated the clinical course of GAVE and identified t..

Gastroenterology / Image of interest Digital ulcerations in amyopathic dermatomyositis Hye In Cho, Ju Hee Han, Youngjae Park Korean J Intern Med. 2026;41(1):175-177.   Published online December 4, 2025 DOI: https://doi.org/10.3904/kjim.2025.023

Gastroenterology / Review From bench to bedside: pancreatic juice as a platform for biomarker discovery in pancreatic disease Pradeep K. Siddappa, Niwen Kong, Alice Lee, Yi Jiang, Walter G. Park Korean J Intern Med. 2026;41(1):15-30.   Published online January 1, 2026 DOI: https://doi.org/10.3904/kjim.2025.216       Pancreatic juice (PJ) analysis has emerged as a promising modality for the diagnosis of pancreatic diseases, particularly pancreatic ductal adenocarcinoma and chronic pancreatitis. This review explores the role of PJ analysis in identifying biomarkers for the early detection and differentiation of p..

Gastroenterology / Original Article Risk of colorectal cancer in kidney transplant recipients and patients with end-stage renal disease undergoing hemodialysis Yongchel Ahn, Hoon Yu, Yoonjong Bae, Mina Kim, Seung Bum Lee Korean J Intern Med. 2025;40(6):952-960.   Published online October 28, 2025 DOI: https://doi.org/10.3904/kjim.2025.015                 Background/Aims: Assessing the risk of colorectal cancer (CRC) after kidney transplantation (KT) in patients with endstage renal disease (ESRD) receiving dialysis is crucial to determine KT’s risks and benefits. In Korea, the study results remain unclear. Therefore, using a nationwide health scree..

Gastroenterology / Original Article Exosomal miRNA-720 as a potential diagnostic and prognostic biomarker for hepatocellular carcinoma Ji Min Kim, Hye Seon Kim, Jin Seoub Kim, Ji Won Han, Soon Kyu Lee, Heechul Nam, Pil Soo Sung, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Jeong Won Jang Korean J Intern Med. 2025;40(6):939-951.   Published online October 31, 2025 DOI: https://doi.org/10.3904/kjim.2024.439              Web of Science 1                        Background/Aims: Circulating exosomal microRNAs (miRNAs) can serve as diagnostic and prognostic biomarkers for cancer. This study aimed to identify specific miRNAs in serum exosomes of patients with hepatocellular carcinoma (HCC) and validate their biological functions as novel diagnostic and predic..

Gastroenterology / Original Article Live zoster vaccination and hepatobiliary risk reduction: a nationwide South Korean study Junyeol Kim, Kyeongmin Lee, Jiyeon Oh, Hayeon Lee, Jong-In Chang, Tae Young Park, Dong Keon Yon, Hyoung-Chul Oh Korean J Intern Med. 2025;40(5):747-758.   Published online August 29, 2025 DOI: https://doi.org/10.3904/kjim.2025.171              Web of Science 2    Crossref 2                      Background/Aims: Herpes zoster (HZ) vaccination is primarily administered to prevent shingles, yet its systemic immunomodulatory effects may offer protection against other organ-related diseases, including hepatobiliary and pancreatic diseases. Therefore, this emulated target trial aimed to evaluate..

Gastroenterology / Original Article Predicted pro-inflammatory high-sensitivity C-reactive protein score and inflammatory bowel disease: a cross-sectional study Dong Hyun Kim, Akinkunmi Paul Okekunle, Jioh Kang, Hyun-Soo Kim, Sang Hoon Kim, Min Kyu Jung, Jae Ho Park, Soo Young Na, Hoonjai Chun, Jung Eun Lee, Yun Jeong Lim Korean J Intern Med. 2025;40(5):734-746.   Published online July 17, 2025 DOI: https://doi.org/10.3904/kjim.2025.038                      Background/Aims: The role of pro-inflammatory factors in the pathogenesis of inflammatory bowel diseases (IBD), is not well understood. This study investigated the association between the predicted pro-inflammatory high-sensitivity C-reactive protein (hs-CRP) score and IBD. Methods: This study invo..

Gastroenterology / Original Article Impact of body mass index on clinical outcomes in intestinal Behçet’s disease Daye Park, Jihye Park, Soo Jung Park, Jae Jun Park, Tae Il Kim, Jae Hee Cheon Korean J Intern Med. 2025;40(4):606-615.   Published online July 1, 2025 DOI: https://doi.org/10.3904/kjim.2024.349                      Background/Aims: The impact of body mass index (BMI) on the clinical outcomes of intestinal Behçet’s disease (BD) remains unclear. This study assessed the association between BMI and disease progression. Methods: A retrospective analysis of 760 patients with intestinal BD was conducted. Patients were..

Gastroenterology / Original Article Submucosal saline injection and mini-probe endoscopic ultrasound to assess endoscopic resectability of colorectal subepithelial tumors Jung-Bin Park, Ji Eun Baek, June Hwa Bae, Seung Wook Hong, Sung Wook Hwang, Sang Hyoung Park, Byong Duk Ye, Jeong-Sik Byeon, Seung-Jae Myung, Suk-Kyun Yang, Dong-Hoon Yang Korean J Intern Med. 2025;40(4):592-605.   Published online July 1, 2025 DOI: https://doi.org/10.3904/kjim.2024.384                      Background/Aims: This study aimed to evaluate the feasibility and outcomes of mini-probe endoscopic ultrasound (mEUS) followed by submucosal saline injection (SSI-mEUS) for assessing the endoscopic resectability of colorectal subepithelial lesions (SELs). Methods: From January 2020 to December 2023..

Gastroenterology / Original Article Prevalence of cholesterol gallstones in a Korean population over a 14-year period Gyumin Lee, Jeong Yoon Suh, Junyeol Kim, Tae Young Park, Jae Hyuk Do, Yoo Shin Choi, Seung Eun Lee, Tae Yoon Lee, Hyun Kang, Hyoung-Chul Oh Korean J Intern Med. 2025;40(4):584-591.   Published online June 30, 2025 DOI: https://doi.org/10.3904/kjim.2025.090                 Background/Aims: The incidence of cholesterol gallstones has increased in the last few decades. This study aimed to evaluate the prevalence of cholesterol gallstones in Korea over a 14-year period, analyze any changes, and identify the predisposing factors. Methods: A total of 3,909 patients underw..

Gastroenterology / Original Article Distinct microbial signatures of liquid biopsy samples during gastric carcinogenesis and insights from extracellular vesicle analysis Hee Sang You, Jae Yong Park, Hochan Seo, Beom Jin Kim, Jae Gyu Kim Korean J Intern Med. 2025;40(4):571-583.   Published online July 1, 2025 DOI: https://doi.org/10.3904/kjim.2024.339              Crossref 1                      Background/Aims: The early detection of gastric cancer is crucial for improving patient outcomes. However, its pathogenesis is not fully understood. The microbiome and extracellular vesicles (EVs) might play a role in gastric carcinogenesis. We aimed to identify gastric-carcinogenesis-associated mic..

Gastroenterology / Image of interest Unusual polypoid mass in the colon Seung-Woo Lee, Jong Ok Kim Korean J Intern Med. 2025;40(3):524-525.   Published online February 17, 2025 DOI: https://doi.org/10.3904/kjim.2024.327

Gastroenterology / Original Article Medical disputes involving lower gastrointestinal endoscopies: cases from the Korean Medical Dispute Mediation and Arbitration Agency Eun Hye Oh, Jeong Eun Shin, Jun Yong Bae, Yoon Suk Lee, Yehyun Park, Yong Hwan Kwon, Chang Nyol Paik, Jun Kyu Lee, Tae Hee Lee Korean J Intern Med. 2025;40(3):404-426.   Published online April 30, 2025 DOI: https://doi.org/10.3904/kjim.2024.343              Web of Science 2    Crossref 1                      Background/Aims: As the number of lower gastrointestinal endoscopies and high-risk examinees increases, the incidence of adverse events associated with these endoscopies has also increased. Medical disputes and lawsuits related to adverse events are rapidly increasing. Methods: Medical disputes rel..

Gastroenterology / Original Article Endoscopic features of cytomegalovirus disease of the upper gastrointestinal tract between transplant and non-transplant patients Yuri Kim, Do Hoon Kim, Myeongsook Seo, Hee Kyong Na, Kee Wook Jung, Ji Yong Ahn, Jeong Hoon Lee, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung Korean J Intern Med. 2025;40(3):394-403.   Published online March 25, 2025 DOI: https://doi.org/10.3904/kjim.2024.250              Web of Science 1    Crossref 1                 Background/Aims: Cytomegalovirus (CMV) disease in the upper gastrointestinal (UGI) tract frequently occurs in immunocompromised patients. However, data regarding UGI CMV disease in non-transplant patients compared with those in transplant recipients are limited. Therefore, we compared the clinical c..

Gastroenterology / Review Herpes zoster infection in patients with inflammatory bowel disease Dong Hyun Kim, Sang-Bum Kang Korean J Intern Med. 2025;40(3):347-356.   Published online April 30, 2025 DOI: https://doi.org/10.3904/kjim.2024.342              Web of Science 1    Crossref 1                 Patients with inflammatory bowel disease (IBD) are at increased risk of herpes zoster (HZ), particularly those receiving immunosuppressive treatments such as corticosteroids, thiopurines, and biologics, which elevate the likelihood of varicella-zoster virus reactivation. Despite this, vaccination ra..

Gastroenterology / Editorial Tissue-invasive upper gastrointestinal cytomegalovirus disease in transplant and non-transplant patients Seokin Kang Korean J Intern Med. 2025;40(3):343-344.   Published online April 30, 2025 DOI: https://doi.org/10.3904/kjim.2025.096

Gastroenterology / Original Article Characteristics and outcomes of portal vein thrombosis in patients with inflammatory bowel disease in Korea Ki Jin Kim, Su-Bin Song, Jung-Bin Park, June Hwa Bae, Ji Eun Baek, Ga Hee Kim, Min-Jun Kim, Seung Wook Hong, Sung Wook Hwang, Dong-Hoon Yang, Byong Duk Ye, Jeong-Sik Byeon, Seung-Jae Myung, Suk-Kyun Yang, Chang Sik Yu, Yong-Sik Yoon, Jong-Lyul Lee, Min Hyun Kim, Ho-Su Lee, Sang Hyoung Park Korean J Intern Med. 2025;40(2):243-250.   Published online December 23, 2024 DOI: https://doi.org/10.3904/kjim.2024.181                 Background/Aims: Portal vein thrombosis (PVT) frequently occurs in patients with inflammatory bowel disease (IBD), particularly when influenced by factors such as abdominal infections, IBD flare-ups, or surgical procedures. The implications of PVT range from immediate issues such as intestinal ische..