Pulmonology / Review Biomarkers of the relationship of particulate matter exposure with the progression of chronic respiratory diseases Junghyun Kim, Soo Jie Chung, Woo Jin Kim Korean J Intern Med. 2024;39(1):25-33.   Published online January 1, 2024 DOI: https://doi.org/10.3904/kjim.2023.393              Web of Science 1    Crossref 2                      A high level of particulate matter (PM) in air is correlated with the onset and development of chronic respiratory diseases. We conducted a systematic literature review, searching the MEDLINE, EMBASE, and Cochrane databases for studies of biomarkers of the effect of PM exposure on chronic respirator..

Pulmonology / Original Article Sex differences in chronic obstructive pulmonary disease characteristics: the Korea National Health and Nutrition Examination Survey 2007–2018 Moon Seong Baek, Haegwang Shin, Kang-Mo Gu, Hae In Jung, Won Young Kim, Jae-Woo Jung, Jong-Wook Shin, Sun-Young Jung, Jae-Yeol Kim Korean J Intern Med. 2024;39(1):137-147.   Published online December 14, 2023 DOI: https://doi.org/10.3904/kjim.2023.036              Web of Science 3    Crossref 3                 Background/Aims: Chronic obstructive pulmonary disease (COPD) is less prevalent in females than males, but it affects mortality in females. There may be sex differences in the clinical characteristics of COPD. Methods: We analyzed the Korea National Health and Nutrition Examination Survey dataset f..

Pulmonology / Original Article Short-acting β2-agonist prescriptions in patients with asthma: findings from the South Korean cohort of SABINA III Kwang-Ha Yoo, Sang-Ha Kim, Sang-Heon Kim, Ji-Yong Moon, Heung-Woo Park, Yoon-Seok Chang, Maarten J.H.I Beekman Korean J Intern Med. 2024;39(1):123-136.   Published online December 7, 2023 DOI: https://doi.org/10.3904/kjim.2023.086                      Background/Aims: Despite short-acting β2-agonist (SABA) overuse being associated with poor asthma outcomes, data on SABA use in South Korea is scarce. Herein, we describe prescription patterns of SABA and other asthma medications in patients from the South Korean cohort of the SABA use IN Asthma (SAB..

Pulmonology / Original Article Alterations in lung and gut microbiota reduce diversity in patients with nontuberculous mycobacterial pulmonary disease Ji Yeon Choi, Bora Shim, Youngmok Park, Young Ae Kang Korean J Intern Med. 2023;38(6):879-892.   Published online October 23, 2023 DOI: https://doi.org/10.3904/kjim.2023.097              Web of Science 2    Crossref 4                      Background/Aims: Although the incidence of nontuberculous mycobacteria pulmonary disease (NTM-PD), a chronic infectious disease, is increasing, lung and gut microbiota dysbiosis in NTM patients has rarely been studied and was therefore the focus of this study. Methods: We analyzed the microbiota di..

Pulmonology / Review Perioperative immunotherapy in stage IB-III non-small cell lung cancer: a critical review of its rationale and considerations Jae Kyeom Sim, Juwhan Choi, Sung Yong Lee Korean J Intern Med. 2023;38(6):787-796.   Published online November 1, 2023 DOI: https://doi.org/10.3904/kjim.2023.345              Web of Science 3    Crossref 3                 Lung cancer is a dismal disease as a leading cause of overall cancer death, but the development of immune checkpoint inhibitors (ICIs) in driver gene mutation negative metastatic non-small cell lung cancer (NSCLC) is changing the paradigm of lung cancer treatment. Recently, ICIs are expanding their ..

Pulmonology / Image of interest An unusual cause of pneumonia: Strongyloides stercoralis infection Chun-Jing Lu, Jin-Yan Zhang, Wei-Feng Huang Korean J Intern Med. 2023;38(5):781-782.   Published online June 20, 2023 DOI: https://doi.org/10.3904/kjim.2023.064

Pulmonology / Original Article The serotype-specific prevalence of pneumococci in hospitalized pneumonia patients with COPD: a prospective, multi-center, cohort study Jae Yeol Kim, Jae-Woo Jung, Min-Jong Kang, Deog Kyeom Kim, Hayoung Choi, Young-Jae Cho, Seung Hun Jang, Chang-Hoon Lee, Yeon Mok Oh, Ji Sook Park Korean J Intern Med. 2023;38(5):714-724.   Published online August 17, 2023 DOI: https://doi.org/10.3904/kjim.2023.152              Web of Science 1    Crossref 1                 Background/Aims: The overall incidence of pneumococcal pneumonia is declining. However, the change in the pathogenic distribution of community-acquired pneumonia (CAP) in chronic obstructive pulmonary disease (COPD) patients and the serotype specificity of Streptococcus pneumoniae have not be..

Pulmonology / Original Article The impact of antimicrobial de-escalation therapy in culture-negative pneumonia: a systematic review and meta-analysis Jae-Uk Song, Jonghoo Lee Korean J Intern Med. 2023;38(5):704-713.   Published online August 17, 2023 DOI: https://doi.org/10.3904/kjim.2023.115              Web of Science 2    Crossref 2                      Background/Aims: Antimicrobial de-escalation (ADE) remains a challenging strategy in the treatment of pneumonia. We investigated the outcomes of ADE as measured by mortality and duration of the use of antibiotics in patients with culture- negative pneumonia. Methods: We performed a systematic revie..

Pulmonology / Image of interest An unusual cause of a bronchopleural fistula Dongyoon Keum, Mincheol Chae, Ilseon Hwang, Hyun Jung Kim Korean J Intern Med. 2023;38(4):574-575.   Published online March 27, 2023 DOI: https://doi.org/10.3904/kjim.2023.060

Pulmonology / Corrigendum Microbiologic pattern and clinical outcome of non-ICU-acquired pneumonia: Korean HAP registry analysis Jin Ho Jang, Hye Ju Yeo, Taehwa Kim, Woo Hyun Cho, Kyung Hoon Min, Sang-Bum Hong, Ae-Rin Baek, Hyun-Kyung Lee, Changhwan Kim, Youjin Chang, Hye Kyeong Park, Jee Youn Oh, Heung Bum Lee, Soohyun Bae, Jae Young Moon, Kwang Ha Yoo, Hyun-Il Gil, Kyeongman Jeon; on behalf of the Korean HAP/VAP Study Group Korean J Intern Med. 2023;38(3):450-450.   Published online April 24, 2023 DOI: https://doi.org/10.3904/kjim.2021.348.e1              Web of Science 1    Crossref 1 Corrects: Korean J Intern Med 2022 7; 37(4): 800

Pulmonology / Image of interest Diffuse pleural thickening with nodularity in a healthy young woman Kyongmin Sarah Beck, Yeoun Eun Sung, Sook Hee Hong, Seok Hwan Moon, Ji Young Kang Korean J Intern Med. 2023;38(3):444-445.   Published online December 27, 2022 DOI: https://doi.org/10.3904/kjim.2022.355

Pulmonology / Original Article Corticosteroid outcome may be dependent of duration of use in severe COVID-19 [letter] Jin Hyoung Kim, Yong Sub Na, Song-I Lee, Youn Young Moon, Beom Seuk Hwang, Ae-Rin Baek, Won-Young Kim, Bo Young Lee, Gil Myeong Seong, Moon Seong Baek Korean J Intern Med. 2023;38(3):382-392.   Published online April 11, 2023 DOI: https://doi.org/10.3904/kjim.2022.201              Web of Science 4    Crossref 4                      Background/Aims: For patients hospitalized with coronavirus disease 2019 (COVID-19) who require supplemental oxygen, the evidence of the optimal duration of corticosteroid is limited. This study aims to identify whether long-term use of corticosteroids is associated with decreased mortality. Method..

Pulmonology / Original Article Real-world evaluation of atezolizumab and etoposide-carboplatin as a first-line treatment for extensive-stage small cell lung cancer Soo Han Kim, Eun Jung Jo, Jeongha Mok, Kwangha Lee, Ki Uk Kim, Hye-Kyung Park, Min Ki Lee, Jung Seop Eom, Mi-Hyun Kim Korean J Intern Med. 2023;38(2):218-225.   Published online February 21, 2023 DOI: https://doi.org/10.3904/kjim.2022.361              Web of Science 12    Crossref 11                 Background/Aims: Despite the obvious benefits of adding immune checkpoint inhibitors to platinum-etoposide chemotherapy in patients with extensive-stage small-cell lung cancer (ES-SCLC), real-world data remain scarce. Methods: This retrospective study included 89 patients with ES-SCLC treated with ..

Pulmonology / Original Article Timing of corticosteroids in non-severe non-hospitalized COVID-19 patients: open-label, two-center, randomized controlled study (TICS-COV19 study) Emad R. Issak, Mariam M. Amin Korean J Intern Med. 2023;38(2):207-217.   Published online January 17, 2023 DOI: https://doi.org/10.3904/kjim.2022.232              Web of Science 3    Crossref 5                 Background/Aims: Corticosteroids (CSs) are frequently used in coronavirus disease 2019 (COVID-19); however, their utility remains controversial in mild to moderate cases. The timing of CSs initiation during the disease course remains unaddressed. The study aims to evaluate the impact of early CSs in..

Pulmonology / Editorial Corticosteroids for non-severe COVID-19 infections? Too early to conclude Sunghoon Park Korean J Intern Med. 2023;38(2):144-146.   Published online February 27, 2023 DOI: https://doi.org/10.3904/kjim.2023.046              Web of Science 1    Crossref 1

Pulmonology / Original Article Clinical outcomes of and risk factors for secondary infection in patients with severe COVID-19: a multicenter cohort study in South Korea Yong Sub Na, Ae-Rin Baek, Moon Seong Baek, Won-Young Kim, Jin Hyoung Kim, Bo young Lee, Gil Myeong Seong, Song-I Lee Korean J Intern Med. 2023;38(1):68-79.   Published online November 24, 2022 DOI: https://doi.org/10.3904/kjim.2022.084              Web of Science 4    Crossref 4                      Background/Aims: Secondary infection with influenza virus occurs in critically ill patients and is associated with substantial morbidity and mortality; however, there is limited information about it in patients with severe coronavirus disease 2019 (COVID-19). Thus, we investigated the clinical outco..