| Reviews |
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Recent Advances in Mechanisms and Treatments of Airway Remodeling in Asthma: A Message from the Bench Side to the Clinic
Jae Youn Cho
Korean J Intern Med. 2011;26(4):367-383. Published online November 28, 2011
Airway remodeling in asthma is a result of persistent inflammation and epithelial damage in response to repetitive injury. Recent studies have identified several important mediators associated with airway remodeling in asthma, including transforming growth factor-β, interleukin (IL)-5, basic fib..
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Endoscopic Therapy in Chronic Pancreatitis
Damien Meng Yew Tan, Stuart Sherman
Korean J Intern Med. 2011;26(4):384-399. Published online November 28, 2011
Chronic pancreatitis (CP) is a debilitating disease that can result in chronic abdominal pain, malnutrition, and other related complications. The main aims of treatment are to control symptoms, prevent disease progression, and correct any complications. A multidisciplinary approach involving medi..
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| Editorial |
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Is the Low-Thalidomide Dose MPT Regimen Beneficial?
Chang-Ki Min
Korean J Intern Med. 2011;26(4):400-402. Published online November 28, 2011
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| Original Articles |
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A Combination of Melphalan, Prednisone, and 50 mg Thalidomide Treatment in Non-Transplant-Candidate Patients with Newly Diagnosed Multiple Myeloma
Hye Jung Chang, Jae Hoon Lee, Young Rok Do, Sung-Hwa Bae, Jung-Lim Lee, Seung Hyun Nam, Sung-Soo Yoon, Soo-Mee Bang
Korean J Intern Med. 2011;26(4):403-409. Published online November 28, 2011
Background/AimsThe clinical efficacy and safety of a three-drug combination of melphalan, prednisone, and thalidomide were assessed in patients with multiple myeloma who were not candidates for high-dose therapy as a first-line treatment. Because the side effects of thalidomid..
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Alteration of Left Ventricular Function with Dobutamine Challenge in Patients with Myocardial Bridge
Joon-Hyung Jhi, Kyoung-Im Cho, Jong-kun Ha, Chan-Woo Jung, Bong-Jae kim, Seong-Oh Park, A-Ra Jo, Seong-Man Kim, Hyeon-Gook Lee, Tae-Ik Kim
Korean J Intern Med. 2011;26(4):410-420. Published online November 28, 2011
Background/AimsThe aim of this study was to identify changes in left ventricular (LV) performance in patients with a myocardial bridge (MB) in the left anterior descending coronary artery during resting and in an inotropic state. MethodsMyocardi..
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Sound Analysis in an In Vitro Endotracheal Tube Model
Young Sik Park, Young Wook Kee, Kwang Suk Park, Jinwoo Lee, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Seok-Chul Yang
Korean J Intern Med. 2011;26(4):421-426. Published online November 28, 2011
Background/AimsComplete endotracheal tube obstruction is a medical emergency, and partial occlusion causes increased breathing rates and failure to wean off mechanical ventilation. Partial occlusion may be underestimated due to the lack of proper detection methods. We tested w..
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Gender Differences in Susceptibility to Smoking among Patients with Lung Cancer
Jeong-Seon Ryu, Sang-Hoon Jeon, Jung-Soo Kim, Jung Hwan Lee, Seong Hyun Kim, Ji Taek Hong, Ju Hong Jeong, Ji Joong Jeong, Myung Dong Lee, Sang Joon Min, Hae-Seong Nam, Jae-Hwa Cho, Seung-Min Kwak, Hong Lyeol Lee, Hyun-Jung Kim
Korean J Intern Med. 2011;26(4):427-431. Published online November 28, 2011
Background/AimsTo determine whether female smokers are more or less susceptible to the detrimental pulmonary-function effects of smoking when compared to male smokers among patients with lung cancer. MethodsPack-years and pulmonary function indi..
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Serum TSH Level in Healthy Koreans and the Association of TSH with Serum Lipid Concentration and Metabolic Syndrome
Yeo Kyung Lee, Jo Eun Kim, Hyun Ju Oh, Kyung Sun Park, Soo Kyung Kim, Seok Won Park, Moon Jong Kim, Yong Wook Cho
Korean J Intern Med. 2011;26(4):432-439. Published online November 28, 2011
Background/AimsThe proper treatment of subclinical hypothyroidism and the normal range of serum thyroid stimulating hormone (TSH) concentration are intensely debated. However, few reports have investigated TSH concentrations in Asian ethnic groups. Therefore, the present study..
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Causes of Different Estimates of the Prevalence of Metabolic Syndrome in Korea
Hyeon Chang Kim, Dae Jung Kim
Korean J Intern Med. 2011;26(4):440-448. Published online November 28, 2011
Background/AimsReports of the prevalence of and trends in metabolic syndrome in Korea have been inconsistent. Thus, we investigated the reasons underlying these inconsistencies. MethodsWe estimated the prevalence of metabolic syndrome using diff..
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Clinical Implications of Elevated Antiphospholipid Antibodies in Adult Patients with Primary Immune Thrombocytopenia
Young-Joon Yang, Gak-Won Yun, Ik-Chan Song, Seung-Woo Baek, Kyu-Seop Lee, Hye Won Ryu, Myung-Won Lee, Hyo-Jin Lee, Hwan-Jung Yun, Samyong Kim, Deog-Yeon Jo
Korean J Intern Med. 2011;26(4):449-454. Published online November 28, 2011
Background/AimsAntiphospholipid antibodies (aPL) have been detected in various proportions of patients with primary immune thrombocytopenia (ITP), but the clinical significance of this is debatable. The present study aimed to determine the frequency and clinical implications o..
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| Case Reports |
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Takotsubo Cardiomyopathy: A Case of Persistent Apical Ballooning Complicated by an Apical Mural Thrombus
Pil Hyung Lee, Jae-Kwan Song, In Keun Park, Byung Joo Sun, Seung Geun Lee, Ji Hye Yim, Hyung Oh Choi
Korean J Intern Med. 2011;26(4):455-459. Published online November 28, 2011
Takotsubo cardiomyopathy (TTC) is an infrequent cardiac syndrome characterized by acute onset chest pain with apical ballooning on echocardiography. It is often triggered by severe emotional or physical stress, and in contrast to acute myocardial infarction (AMI), the regional wall motion abnorma..
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Central Venous Stenosis Caused by Traction of the Innominate Vein due to a Tuberculosis-Destroyed Lung
Eun Ju Song, Dae Hyun Baek, Young-Hwan Hwang, So-Young Lee, Young-Kwon Cho, Su-Ah Sung
Korean J Intern Med. 2011;26(4):460-462. Published online November 28, 2011
We report a case of central venous stenosis due to a structural deformity caused by a tuberculosis-destroyed lung in a 65-year-old woman. The patient presented with left facial edema. She had a history of pulmonary tuberculosis, and the chest X-ray revealed a collapsed left lung. Angiography show..
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Acute Kidney Injury due to Sodium Bromate Intoxication: A Report of Two Cases
Dong Hwan Ryu, Kyung Ae Jang, Seok Min Kim, Jong Won Park, Jun Young Do, Kyung Woo Yoon
Korean J Intern Med. 2011;26(4):463-465. Published online November 28, 2011
Sodium bromate is a strong oxidant used as a neutralizing solution in hair permanents, as well as an auxiliary agent in printing and dyeing. Accidental or deliberate ingestion of bromate solution has rarely been reported in Korea. The clinical manifestations of bromate intoxication are vomiting, ..
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An Adult Case of Chronic Active Epstein-Barr Virus Infection with Interstitial Pneumonitis
Eun-Jeong Joo, Young Eun Ha, Dong Sik Jung, Hae Suk Cheong, Yu Mi Wi, Jae-Hoon Song, Kyong Ran Peck
Korean J Intern Med. 2011;26(4):466-469. Published online November 28, 2011
Chronic active Epstein-Barr virus (CAEBV) infection is characterized by persistent infectious mononucleosis-like symptoms, an unusual pattern of Epstein-Barr virus (EBV) antibodies, detection of the EBV genome in affected tissues or peripheral blood, and chronic illness that cannot be attributed ..
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A Case of Minimal Change Disease Treated Successfully with Mycophenolate Mofetil in a Patient with Systemic Lupus Erythematosus
Young Hoon Hong, Dae Young Yun, Yong Wook Jung, Myung Jin Oh, Hyun Je Kim, Choong Ki Lee
Korean J Intern Med. 2011;26(4):470-473. Published online November 28, 2011
The World Health Organization classifies lupus nephritis as class I to V or VI. However, a few cases of minimal change glomerulopathy have been reported in association with systemic lupus erythematosus (SLE). Mycophenolate mofetil has been shown to be effective for treatment of minimal change dis..
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| Letter to the editor |
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Two Cases of Scrub Typhus Presenting with Guillain-Barré Syndrome with Respiratory Failure
Il Nam Ju, Jung Woo Lee, Sung Yeoun Cho, Seung Jee Ryu, Youn Jeong Kim, Sang Il Kim, Moon Won Kang
Korean J Intern Med. 2011;26(4):474-476. Published online November 28, 2011
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| Images of interest |
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Nododuodenal Fistula Caused by Tuberculosis
Dong-Gun Lee, Gwang-Ha Kim
Korean J Intern Med. 2011;26(4):477-477. Published online November 28, 2011
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Excretion of Urine Mixed with Air and Fecal Material
Sik Lee, Soo Teik Lee
Korean J Intern Med. 2011;26(4):478-478. Published online November 28, 2011
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