Hemato-oncology
Molecular targeted therapy for advanced gastric cancer
Jong Gwang Kim
Korean J Intern Med. 2013;28(2):149-155. Published online February 27, 2013
Although medical treatment has been shown to improve quality of life and prolong survival, no significant progress has been made in the treatment of advanced gastric cancer (AGC) within the last two decades. Thus, the optimum standard first-line chemotherapy regimen for AGC remains debatable, and..
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Clinical Features of Patients on Home Oxygen Therapy Due to Chronic Respiratory Failure at One University Hospital
Kyoung Hee Kim, Tae Yun Park, Eun Sun Kim, Keun Bum Chung, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Seok-Chul Yang
Korean J Intern Med. 2012;27(3):311-316. Published online September 1, 2012
Background/AimsHome oxygen therapy (HOT) costs a great deal every year and demand for the service is growing. In Korea, health insurance has covered HOT since November 1, 2006. The objective of this study was to evaluate clinical features of patients who used long-term HOT due..
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Role of Photodynamic Therapy in the Palliation of Obstructing Esophageal Cancer
Hyeon Young Yoon, Young Koog Cheon, Hye Jin Choi, Chan Sup Shim
Korean J Intern Med. 2012;27(3):278-284. Published online September 1, 2012
Background/AimsThe aim of this non-randomized study was to determine the role of photodynamic therapy (PDT) in a multimodal approach for the palliation of advanced esophageal carcinoma. MethodsTwenty consecutive patients with obstructing esophag..
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Practical Treatments for Constipation in Korea
Kyung-Sik Park, Suck-Chei Choi, Moo-In Park, Jeong-Eun Shin, Kee-Wook Jung, Seong-Eun Kim, Tae-Hee Lee, Hoon-Sup Koo,
Korean J Intern Med. 2012;27(3):262-270. Published online September 1, 2012
Constipation is a digestive symptom that is frequently seen in clinical practice. Its prevalence has been reported to be 2% to 20%, depending on geographical region. Despite the rapid development of medical science, systematic studies on constipation have been rarely conducted in Korea. Recently,..
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Development of Brugada Syndrome Following Photodynamic Therapy in a Patient with Cholangiocarcinoma
Duk Won Bang, Min Su Hyon, Young Duk Cho, Sung Koo Kim, Young Joo Kwon
Korean J Intern Med. 2012;27(1):95-97. Published online February 28, 2012
Brugada syndrome can be unmasked by several conditions including a febrile state, marked leukocytosis, and electrolyte disturbances. Herein, we describe a 62-year-old man with cholangiocarcinoma in the first reported case of Brugada syndrome onset following photodynamic therapy.
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Feasibility of Non-TBI Conditioning with Busulfan and Fludarabine for Allogeneic Stem Cell Transplantation in Lymphoid Malignancy
Ho Cheol Shin, Yoo Jin Lee, Joon Ho Joon Ho, Soo Jung Lee, Byung Woog Kang, Yee Soo Chae, Jong Gwang Kim, Jun Young Choi, Jong Won Seo, Yu Kyung Kim, Jang Soo Suh, Sang Kyun Sohn
Korean J Intern Med. 2012;27(1):72-83. Published online February 28, 2012
Background/AimsThis retrospective study evaluated the transplantation outcomes of patients with adult lymphoid malignancies who received chemotherapy-based conditioning with busulfan and fludarabine (BuFlu) and busulfan and cyclophosphamide (BuCy2). Method..
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Optimization of Stent Deployment by Intravascular Ultrasound
Hyuck-Jun Yoon, Seung-Ho Hur
Korean J Intern Med. 2012;27(1):30-38. Published online February 28, 2012
Intravascular ultrasound (IVUS) is a useful diagnostic method that provides valuable information in addition to angiography regarding the coronary vessel lumen, dimensions, plaque burden, and characteristics. The major use of IVUS in coronary intervention is to guide interventional strategies and..
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Recent Advances in Mechanisms and Treatments of Airway Remodeling in Asthma: A Message from the Bench Side to the Clinic
Jae Youn Cho
Korean J Intern Med. 2011;26(4):367-383. Published online November 28, 2011
Airway remodeling in asthma is a result of persistent inflammation and epithelial damage in response to repetitive injury. Recent studies have identified several important mediators associated with airway remodeling in asthma, including transforming growth factor-β, interleukin (IL)-5, basic fib..
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Application of Helical Tomotherapy for Two Cases of Advanced Hepatocellular Carcinoma
Joon Sung Kim, Chan Ran You, Jeong Won Jang, Si-Hyun Bae, Jong Yong Choi, Seung Kew Yoon, Chul Seung Kay
Korean J Intern Med. 2011;26(2):201-206. Published online June 1, 2011
The role of radiotherapy in the treatment of hepatocellular carcinoma (HCC) has been limited to date, because the liver has a low tolerance to radiation. However, reconstructing tumors and surrounding organs via a three-dimensional conformal planning system can avoid excess radiotherapy exposure ..
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Endoscopic Cryotherapy of Lung and Bronchial Tumors: A Systematic Review
Seon-Heui Lee, Won-Jung Choi, Sook-Whan Sung, Young-Kyoon Kim, Chi-Hong Kim, Jae-Il Zo, Kwang-Joo Park
Korean J Intern Med. 2011;26(2):137-144. Published online June 1, 2011
Background/AimsWe made a systematic review and evaluation of endoscopic cryotherapy of endobronchial tumors, investigating safety and efficacy. MethodsQualified studies regarding endoscopic cryotherapy of lung tumors were systemically evaluated ..
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Successful Treatment of Stereotactic Body Radiation Therapy Combined with Transarterial Chemolipiodolization for Hepatocellular Carcinoma with Biliary Obstruction
Chan-Kwon Park, Si-Hyun Bae, Hong-Jun Yang, Ho-Jong Chun, Il-Bong Choi, Jong-Young Choi, Seung-Kew Yoon
Korean J Intern Med. 2011;26(1):94-98. Published online March 2, 2011
Conventional radiation therapy (RT) is a widely recognized treatment for hepatocellular carcinoma (HCC). However, conventional RT plays only a limited role in HCC treatment because of its low efficacy and the low tolerance of the liver for this modality. Stereotactic body radiation therapy (SBRT)..
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Regional Anticoagulation with Citrate is Superior to Systemic Anticoagulation with Heparin in Critically Ill Patients Undergoing Continuous Venovenous Hemodiafiltration
Joon-Sung Park, Gheun-Ho Kim, Chong Myung Kang, Chang Hwa Lee
Korean J Intern Med. 2011;26(1):68-75. Published online March 2, 2011
Background/AimsShort hemofilter survival and anticoagulation-related life-threatening complications are major problems in systemic anticoagulation with heparin (SAH) for continuous renal replacement therapy (CRRT). The present study examined if regional anticoagulation with ci..
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The Role of Photodynamic Therapy for Hilar Cholangiocarcinoma
Young Koog Cheon
Korean J Intern Med. 2010;25(4):345-352. Published online November 27, 2010
The prognosis for hilar cholangiocarcinoma is limited by tumor spread along the biliary tree leading to refractory obstructive cholestasis, cholangitis, and liver failure. Palliation with biliary endoprostheses results in median survival times of 4-6 months for advanced bile duct cancer. Photodyn..
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Severe Pulmonary Adverse Effects in Lymphoma Patients Treated with Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) Regimen Plus Rituximab
Kyu-Hyoung Lim, Ho-Il Yoon, Young Ae Kang, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang, Jae Ho Lee, Choon-Taek Lee, Jong Seok Lee
Korean J Intern Med. 2010;25(1):86-92. Published online February 26, 2010
Background/AimsThe aim of our study was to determine the incidence and clinical features of severe pulmonary complications in patients receiving cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or rituximab plus CHOP (R-CHOP) as the initial treatment for lymph..
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Clinical Characteristics of Pulmonary Embolism with Underlying Malignancy
Ji Eun Lee, Hye-Ryoun Kim, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young-Soo Shim, Seok-Chul Yang
Korean J Intern Med. 2010;25(1):66-70. Published online February 26, 2010
Background/AimsThe risk of venous thromboembolism (VTE), which encompasses deep vein thrombosis and pulmonary embolism (PE), increases in patients with cancer. Anticancer treatment is also associated with an increased risk for VTE. We conducted this study to investigate the cl..
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Acute Embolic Occlusion of the Left Common Iliac Artery Treated With Intra-Arterial Thrombolysis and Percutaneous Thrombectomy
Wang-Soo Lee, Kwang Je Lee, Wang Seong Ryu
Korean J Intern Med. 2009;24(2):153-155. Published online June 8, 2009
Acute embolic occlusion of the common iliac artery is a rare medical emergency that is not only limb-threatening, but also potentially life-threatening. Several treatment options exist for acute limb ischemia, although no treatment is clearly best. We report a case of acute embolic occlusion of t..
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Long-Term Survival in a Patient With Ruptured Hepatocellular Carcinoma
Joon Sung Kim, Seung Kew Yoon, Jeong Ah Kim, Chang Wook Kim, Si Hyun Bae, Jong Young Choi, Chan-Kwon Jung
Korean J Intern Med. 2009;24(1):63-67. Published online March 6, 2009
A 57-yr-old woman previously diagnosed with chronic hepatitis B was admitted via the emergency room because she suddenly developed epigastric pain with abdominal distension. On computed tomography (CT), a round enhancing mass was found on the left hepatic lobe with ascites in the peritoneal space..
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The Effect of Residual Renal Function at the Initiation of Dialysis on Patient Survival
Seoung Gu Kim, Nam Ho Kim
Korean J Intern Med. 2009;24(1):55-62. Published online March 6, 2009
Background/AimsThe optimal time point for initiating renal replacement therapy in patients with end-stage renal disease remains controversial. The primary objective of our study was to determine the effects of residual renal function at the beginning of renal replacement thera..
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S-1 Monotherapy as a Neoadjuvant Treatment for Locally Advanced Gastric Cancer
Jong Yul Jung, Sun Young Rha, Joong Bae Ahn, Woo Ick Yang, Sung Hoon Noh, Hyun Cheol Chung, Hei-Cheul Jeung
Korean J Intern Med. 2008;23(1):37-41. Published online March 20, 2008
S-1, a novel oral fluoropyrimidine, is an effective therapeutic agent for gastric cancer. Herein, we report a case with locally advanced gastric cancer that achieved a curative resection after S-1 monotherapy as neoadjuvant treatment. A 68-year-old man was diagnosed with gastric cancer and massiv..
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Duodenal Mucosa-Associated Lymphoid Tissue Lymphoma: A Case Report
Kyung Hee Woo, Jung Han Kim, Seong Bo Yoon, Joo Hyun Jang, Dong Hun Lee, Seong Ho Hong, Il Hyun Baek
Korean J Intern Med. 2007;22(4):296-299. Published online December 20, 2007
Primary duodenal mucosa associated lymphoid tissue (MALT) lymphoma is very rare, and little is known about its clinical course or effective treatment. We describe a case of primary duodenal MALT lymphoma that was resistant to Helicobacter pylori (H. pylori) eradi..
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