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Original Article
Feasibility of Non-TBI Conditioning with Busulfan and Fludarabine for Allogeneic Stem Cell Transplantation in Lymphoid Malignancy
Ho Cheol Shin, Yoo Jin Lee, Joon Ho Joon Ho, Soo Jung Lee, Byung Woog Kang, Yee Soo Chae, Jong Gwang Kim, Jun Young Choi, Jong Won Seo, Yu Kyung Kim, Jang Soo Suh, Sang Kyun Sohn
Korean J Intern Med. 2012;27(1):72-83. Published online February 28, 2012
Background/AimsThis retrospective study evaluated the transplantation outcomes of patients with adult lymphoid malignancies who received chemotherapy-based conditioning with busulfan and fludarabine (BuFlu) and busulfan and cyclophosphamide (BuCy2). Method..
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Original Article
Normalization of Negative T-Wave on Electrocardiography and Right Ventricular Dysfunction in Patients with an Acute Pulmonary Embolism
Bo-Youn Choi, Dae-Gyun Park
Korean J Intern Med. 2012;27(1):53-59. Published online February 28, 2012
Background/AimsRight ventricular dysfunction (RVD) is associated with poor prognosis in patients with acute pulmonary embolism (APE). Echocardiography and computed tomography (CT)-angiography may be difficult to perform in a serial follow up, unlike electrocardiography (ECG). ..
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Original Article
Validity of Glycated Hemoglobin in Screening and Diagnosing Type 2 Diabetes Mellitus in Chinese Subjects
Yun Yu, Xiao-Jun Ouyang, Qing-Lin Lou, Liu-Bao Gu, Yong-Zhen Mo, Gary T. Ko, Chun-Chung Chow, Wing-Yee So, Ronald Ma, Alice Kong, Nicola Brown, Jennifer Nan, Juliana Chan, Rong-Wen Bian
Korean J Intern Med. 2012;27(1):41-46. Published online February 28, 2012
Background/AimsThe application of glycated hemoglobin (HbA1c) for the diagnosis of diabetes is currently under extensive discussion. In this study, we explored the validity of using HbA1c as a screening and diagnostic test in Chinese subjects recruited in..
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Review
Optimization of Stent Deployment by Intravascular Ultrasound
Hyuck-Jun Yoon, Seung-Ho Hur
Korean J Intern Med. 2012;27(1):30-38. Published online February 28, 2012
Intravascular ultrasound (IVUS) is a useful diagnostic method that provides valuable information in addition to angiography regarding the coronary vessel lumen, dimensions, plaque burden, and characteristics. The major use of IVUS in coronary intervention is to guide interventional strategies and..
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Review
The Role of Optical Coherence Tomography in Coronary Intervention
Mitsuyasu Terashima, Hideaki Kaneda, Takahiko Suzuki
Korean J Intern Med. 2012;27(1):1-12. Published online February 28, 2012
Optical coherence tomography (OCT) is an optical analog of intravascular ultrasound (IVUS) that can be used to examine the coronary arteries and has 10-fold higher resolution than IVUS. Based on polarization properties, OCT can differentiate tissue characteristics (fibrous, calcified, or lipid-ri..
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Letter to the editor
Two Cases of Scrub Typhus Presenting with Guillain-Barré Syndrome with Respiratory Failure
Il Nam Ju, Jung Woo Lee, Sung Yeoun Cho, Seung Jee Ryu, Youn Jeong Kim, Sang Il Kim, Moon Won Kang
Korean J Intern Med. 2011;26(4):474-476. Published online November 28, 2011
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Original Article
Clinical Implications of Elevated Antiphospholipid Antibodies in Adult Patients with Primary Immune Thrombocytopenia
Young-Joon Yang, Gak-Won Yun, Ik-Chan Song, Seung-Woo Baek, Kyu-Seop Lee, Hye Won Ryu, Myung-Won Lee, Hyo-Jin Lee, Hwan-Jung Yun, Samyong Kim, Deog-Yeon Jo
Korean J Intern Med. 2011;26(4):449-454. Published online November 28, 2011
Background/AimsAntiphospholipid antibodies (aPL) have been detected in various proportions of patients with primary immune thrombocytopenia (ITP), but the clinical significance of this is debatable. The present study aimed to determine the frequency and clinical implications o..
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Original Article
Sound Analysis in an In Vitro Endotracheal Tube Model
Young Sik Park, Young Wook Kee, Kwang Suk Park, Jinwoo Lee, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Seok-Chul Yang
Korean J Intern Med. 2011;26(4):421-426. Published online November 28, 2011
Background/AimsComplete endotracheal tube obstruction is a medical emergency, and partial occlusion causes increased breathing rates and failure to wean off mechanical ventilation. Partial occlusion may be underestimated due to the lack of proper detection methods. We tested w..
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Original Article
Alteration of Left Ventricular Function with Dobutamine Challenge in Patients with Myocardial Bridge
Joon-Hyung Jhi, Kyoung-Im Cho, Jong-kun Ha, Chan-Woo Jung, Bong-Jae kim, Seong-Oh Park, A-Ra Jo, Seong-Man Kim, Hyeon-Gook Lee, Tae-Ik Kim
Korean J Intern Med. 2011;26(4):410-420. Published online November 28, 2011
Background/AimsThe aim of this study was to identify changes in left ventricular (LV) performance in patients with a myocardial bridge (MB) in the left anterior descending coronary artery during resting and in an inotropic state. MethodsMyocardi..
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Review
Endoscopic Therapy in Chronic Pancreatitis
Damien Meng Yew Tan, Stuart Sherman
Korean J Intern Med. 2011;26(4):384-399. Published online November 28, 2011
Chronic pancreatitis (CP) is a debilitating disease that can result in chronic abdominal pain, malnutrition, and other related complications. The main aims of treatment are to control symptoms, prevent disease progression, and correct any complications. A multidisciplinary approach involving medi..
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Review
Recent Advances in Mechanisms and Treatments of Airway Remodeling in Asthma: A Message from the Bench Side to the Clinic
Jae Youn Cho
Korean J Intern Med. 2011;26(4):367-383. Published online November 28, 2011
Airway remodeling in asthma is a result of persistent inflammation and epithelial damage in response to repetitive injury. Recent studies have identified several important mediators associated with airway remodeling in asthma, including transforming growth factor-β, interleukin (IL)-5, basic fib..
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Case Report
Acute Generalized Exanthematous Pustulosis Due to Oral Use of Blue Dyes
Osman Sener, Ösman Kose, Özgür Kartal, Mukerrem Safali
Korean J Intern Med. 2011;26(3):360-363. Published online September 13, 2011
Acute generalized exanthematous pustulosis is a rare severe pustular cutaneous adverse reaction characterized by a rapid clinical course with typical histological findings. It is accompanied by fever and acute eruption of non-follicular pustules overlying erythrodermic skin. The causative agents ..
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Case Report
Topical Steroids to Treat Granulomatous Mastitis: A Case Report
Fatih Altintoprak
Korean J Intern Med. 2011;26(3):356-359. Published online September 13, 2011
Idiopathic granulomatous mastitis (IGM) is a rare and chronic benign disease of the breast. Histologically, the disease presents as an intense inflammatory reaction with non-caseated granulomas that are the characteristic symptom of the disease. No consensus exists on the best treatment modality ..
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Case Report
Transcatheter Arterial Embolization as Treatment for a Life-Threatening Retroperitoneal Hemorrhage Complicating Heparin Therapy
Sang-Ho Park, Se-Whan Lee, Ung Jeon, Min-Hyeok Jeon, Seung-Jin Lee, Won-Yong Shin, Dong-Kyu Jin
Korean J Intern Med. 2011;26(3):352-355. Published online September 13, 2011
Spontaneous retroperitoneal hemorrhage is a distinct clinical entity that can present in the absence of specific underlying pathology or trauma and is typically associated with anticoagulation therapy. We report a case of a 74-year-old female patient with a cerebral infarction related to atrial f..
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Original Article
Cyclosporin A Inhibits Albumin Synthesis in Huh7 Cells
Youn Joo Jeon, Yong Soo Kim
Korean J Intern Med. 2011;26(3):314-319. Published online September 13, 2011
Background/AimsHypoalbuminemia occurs frequently in renal transplant recipients immediately after renal transplantation. We studied the regulation of hepatic albumin synthesis by cyclosporin A (CsA) in Huh7 cells. MethodsHuh7 cells were incubate..
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Original Article
Nuclear factor E2-related factor 2 Dependent Overexpression of Sulfiredoxin and Peroxiredoxin III in Human Lung Cancer
Young Sun Kim, Hye Lim Lee, Ki Bum Lee, Joo Hun Park, Wou Young Chung, Keu Sung Lee, Seung Soo Sheen, Kwang Joo Park, Sung Chul Hwang
Korean J Intern Med. 2011;26(3):304-313. Published online September 13, 2011
Background/AimsOxidative stress results in protein oxidation and is implicated in carcinogenesis. Sulfiredoxin (Srx) is responsible for the enzymatic reversal of inactivated peroxiredoxin (Prx). Nuclear factor E2-related factor 2 (Nrf2) binds to antioxidant responsive elements..
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Review
Molecular Epidemiology of Hepatitis B Virus
Jia-Horng Kao
Korean J Intern Med. 2011;26(3):255-261. Published online September 13, 2011
Although safe and effective vaccines for hepatitis B virus (HBV) have been available for nearly three decades, this virus kills at least 600,000 people annually worldwide and remains the leading global cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Because the HBV reverse tr..
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Guideline
Evidence-Based Guidelines for Empirical Therapy of Neutropenic Fever in Korea
Dong-Gun Lee, Sung-Han Kim, Soo Young Kim, Chung-Jong Kim, Wan Beom Park, Young Goo Song, Jung-Hyun Choi
Korean J Intern Med. 2011;26(2):220-252. Published online June 1, 2011
Neutrophils play an important role in immunological function. Neutropenic patients are vulnerable to infection, and except fever is present, inflammatory reactions are scarce in many cases. Additionally, because infections can worsen rapidly, early evaluation and treatments are especially importa..
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Image of interest
A Case of Coarctation of the Aorta Diagnosed by Tardus-Parvus Renal Doppler Flow Patterns
Yun-Hwa Jung, Kwan-Wook Kim, Dae-Yoon Kim, Chul-Seung Lee
Korean J Intern Med. 2011;26(2):216-217. Published online June 1, 2011
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Case Report
False-Positive Hypermetabolic Lesions on Post-Treatment PET-CT after Influenza Vaccination
Jeong-Eun Kim, Eun Kyoung Kim, Dae Ho Lee, Sang-We Kim, Cheolwon Suh, Jung-Shin Lee
Korean J Intern Med. 2011;26(2):210-212. Published online June 1, 2011
We report a case of a 59-year-old man with testicular germ cell tumor who showed new hypermetabolic lesions at the left axillary lymph nodes on a post-treatment positron emission tomography-computed tomography (PET-CT) scan. The hypermetabolic lesions were found to be caused by an influenza vacci..
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