| Reviews |
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Cardiology
Stent thrombosis and optimal duration of dual antiplatelet therapy after coronary stenting in contemporary practice
Min Soo Cho, Duk-Woo Park
Korean J Intern Med. 2017;32(5):769-779. Published online August 22, 2017
The introduction of drug-eluting stents (DES) in the practice of percutaneous coronary intervention (PCI) has substantially reduced angiographic and clinical restenosis but is associated with an increasing propensity for very late stent thrombosis (ST). Among several clinical, lesion, or procedure-r..
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Endocrinology-metabolism
Oncogenes, mitochondrial metabolism, and quality control in differentiated thyroid cancer
Hyon-Seung Yi, Joon Young Chang, Koon Soon Kim, Minho Shong
Korean J Intern Med. 2017;32(5):780-789. Published online August 22, 2017
Thyroid cancer is one of the most common malignancies of endocrine organs, and its incidence rate has increased steadily over the past several decades. Most differentiated thyroid tumors derived from thyroid epithelial cells exhibit slow-growing cancers, and patients with these tumors can achieve a ..
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Nephrology
Pre-existing arterial pathologic changes affecting arteriovenous fistula patency and cardiovascular mortality in hemodialysis patients
Ja Young Lee, Young Ok Kim
Korean J Intern Med. 2017;32(5):790-797. Published online August 22, 2017
The radiocephalic arteriovenous fistula (AVF) provides optimal vascular access for hemodialysis; it has a higher long-term patency rate and fewer complications than other vascular access methods. However, the AVF has a high primary failure rate. The presence of small-diameter vessels at anastomosis ..
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Hemato-oncology
Targeted therapy of ovarian cancer including immune check point inhibitor
Jin Young Kim, Chi Heum Cho, Hong Suk Song
Korean J Intern Med. 2017;32(5):798-804. Published online August 22, 2017
Epithelial ovarian cancer is the eighth most common cause of cancer-related deaths in women because most patients present with advanced stage disease at the time of diagnosis. Although cytoreductive surgery and platinum-based chemotherapy remain the gold standards of treatment, the recurrence rate o..
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Infectious diseases
Voriconazole-refractory invasive aspergillosis
Se Yoon Park, Jung-A Yoon, Sung-Han Kim
Korean J Intern Med. 2017;32(5):805-812. Published online August 24, 2017
Invasive aspergillosis (IA) is one of the most common life-threatening complications in immunocompromised patients. Voriconazole is currently the drug of choice for IA treatment. However, some patients with IA suffer clinical deterioration despite voriconazole therapy. Management of voriconazole-ref..
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| Editorials |
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Significance of duodenal mucosal lesions: can they be a clue to a systemic disease?
Seung Woo Lee
Korean J Intern Med. 2017;32(5):813-815. Published online August 31, 2017
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| Original Articles |
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Gastroenterology
Factors impacting patient cooperation during elective gastroscopy
Sang Pyo Lee, In-Kyung Sung, Jeong Hwan Kim, Sun-Young Lee, Hyung Seok Park, Chan Sup Shim
Korean J Intern Med. 2017;32(5):819-826. Published online August 22, 2017
Background/Aims: Some people have difficulty tolerating upper endoscopy. The cause of and risk factors for this are not well known. The aim of this study was to investigate the factors involved in poor cooperation during screening upper endoscopy.
Methods: A total of 4,422 subjects who underwent a h..
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Identification of distinctive clinical significance in hospitalized patients with endoscopic duodenal mucosal lesions
Yeji Han, Hye-Kyung Jung, Ji Young Chang, Chang Mo Moon, Seong-Eun Kim, Ki-Nam Shim, Sung-Ae Jung, Joo-Young Kim, Ji-Yun Bae, Sae-In Kim, Ji-Hyun Lee, Sanghui Park
Korean J Intern Med. 2017;32(5):827-835. Published online August 21, 2017
Background/Aims: Duodenitis is not infrequent finding in patient undergoing endoscopy. However, hospitalized patients have a higher incidence of secondary duodenal mucosal lesions that might be related with inflammatory bowel disease (IBD), cytomegalovirus (CMV) infection, tuberculosis, immunologic ..
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Cardiology
Masked inherited primary arrhythmia syndromes in sudden cardiac death patients accompanied by coronary vasospasm
Ki Hong Lee, Hyung Wook Park, Jeong Nam Eun, Jeong Gwan Cho, Nam Sik Yoon, Mi Ran Kim, Yo Han Ku, Hyukjin Park, Seung Hun Lee, Jeong Han Kim, Min Chul Kim, Woo Jin Kim, Hyun Kuk Kim, Jae Yeong Cho, Keun-Ho Park, Doo Sun Sim, Hyun Ju Yoon, Kye Hun Kim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong, Jong Chun Park
Korean J Intern Med. 2017;32(5):836-846. Published online August 11, 2017
Background/Aims: Coronary vasospasms are one of the important causes of sudden cardiac death (SCD). Provocation of coronary vasospasms can be useful, though some results may lead to false positives, with patients potentially experiencing recurrent SCD despite appropriate medical treatments. We hypot..
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Geographic and demographic variabilities of quantitative parameters in stress myocardial computed tomography perfusion
Jinoh Park, Hyun-Sook Kim, Hye Jeon Hwang, Dong Hyun Yang, Hyun Jung Koo, Joon-Won Kang, Young-Hak Kim
Korean J Intern Med. 2017;32(5):847-854. Published online July 28, 2017
Background/Aims: To evaluate the geographic and demographic variabilities of the quantitative parameters of computed tomography perfusion (CTP) of the left ventricular (LV) myocardium in patients with normal coronary artery on computed tomography angiography (CTA).
Methods: From a multicenter CTP r..
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Pulmonology
Long-term outcomes of surgery for chronic thromboembolic pulmonary hypertension compared
with medical therapy at a single Korean center
Soo Han Kim, Jae Won Lee, Jung-Min Ahn, Dae-Hee Kim, Jong-Min Song, Sang-Do Lee, Jae Seung Lee
Korean J Intern Med. 2017;32(5):855-864. Published online October 13, 2016
Background/Aims: Pulmonary endarterectomy (PEA) is the gold standard for treating chronic thromboembolic pulmonary hypertension (CTEPH) in Western countries. The aim of this study was to investigate the long-term outcomes of performing PEA on CTEPH patients in comparison with medical therapy at a si..
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The activation of NLRP3-inflammsome by stimulation of diesel exhaust particles in lung tissues from emphysema model and RAW 264.7 cell line
Soo-Taek Uh, So My Koo, Yangki Kim, Kiup Kim, Sungwoo Park, An Soo Jang, Dojin Kim, Yong Hoon Kim, Choon-Sik Park
Korean J Intern Med. 2017;32(5):865-874. Published online August 18, 2017
Background/Aims: Diesel exhaust particles (DEPs) lead to elevation of reactive oxygen species, which can activate the nucleotide-binding oligomerization domain-like receptor (NLR) family members containing the pyrin domain 3 (NLRP3)-inf lammasome. In this study, we elucidated whether NLRP3 -inf lamm..
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Endocrinology-metabolism
Low serum bilirubin level predicts the development of chronic kidney disease in patients with type 2 diabetes mellitus
Kang Hee Ahn, Sang Soo Kim, Won Jin Kim, Jong Ho Kim, Yun Jeong Nam, Su Bin Park, Yun Kyung Jeon, Bo Hyun Kim, In Joo Kim, Yong Ki Kim
Korean J Intern Med. 2017;32(5):875-882. Published online May 31, 2017
Background/Aims: We evaluated whether serum bilirubin levels can predict the development of chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM).
Methods: This was a retrospective observational longitudinal study of patients presenting at the Pusan National University Hospi..
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Nephrology
Caveolin-1 is involved in high glucose accelerated human glomerular mesangial cell senescence
Xin Feng, Wei Gao, Yao Li
Korean J Intern Med. 2017;32(5):883-889. Published online April 6, 2016
Background/Aims: We demonstrated the role of caveolin-1 involved in high glucose (HG)-induced glomerular mesangial cells (GMCs) senescence.
Methods: HG was used to stimulate GMCs. The telomere lengths were analyzed by Southern blot. β-Galactosidase staining was determined. The expressions of caveo..
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Hemato-oncology
Clinical features and treatment outcomes of blastic plasmacytoid dendritic cell neoplasm: a single-center experience in Korea
Hae Su Kim, Hee-Jin Kim, Sun-Hee Kim, Joon Young Choi, Young Hyeh Ko, Won Seog Kim, Chul Won Jung, Seok Jin Kim
Korean J Intern Med. 2017;32(5):890-899. Published online August 18, 2017
Background/Aims: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy that typically presents in the form of skin manifestations with or without lymph node and bone marrow involvement. Given its rarity and recent recognition as a distinct pathological entity, no stan..
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Infectious diseases
Clinical applications of interferon-γ releasing assays for cytomegalovirus to differentiate cytomegalovirus disease from bystander activation: a pilot proof-of-concept study
Sung-Han Kim, Ho-Su Lee, Hyun-Jung Lee, Sun-Mi Kim, Sung Shin, Sang-Hyoung Park, Kyung-Jo Kim, Young-Hoon Kim, Heungsup Sung, Sang-Oh Lee, Sang-Ho Choi, Suk-Kyun Yang, Yang Soo Kim, Jun Hee Woo, Duck-Jong Han
Korean J Intern Med. 2017;32(5):900-909. Published online August 23, 2017
Background/Aims: We evaluated the proposed clinical application of the combined interpretation of host factors and viral factors in two different cytomegalovirus (CMV) co-infection models.
Methods: We prospectively enrolled all human immunodeficiency virus non-infected patients with confirmed P..
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Allergy
Korean version of the Cough Symptom Score: clinical utility and validity for chronic cough
Jae-Woo Kwon, Ji-Yong Moon, Sae-Hoon Kim, Woo-Jung Song, Min-Hye Kim, Min-Gyu Kang, Kyung-Hwan Lim, So-Hee Lee, Sang Min Lee, Jin Young Lee, Hyouk-Soo Kwon, Kyung-Mook Kim, Sang-Heon Kim, Sang-Hoon Kim, Jae-Won Jeong, Cheol-Woo Kim, Sang-Heon Cho, Byung-Jae Lee; Work Group for Chronic Cough, the Korean Academy of Asthma, Allergy and Clinical Immunology
Korean J Intern Med. 2017;32(5):910-915. Published online March 31, 2017
Background/Aims: The Cough Symptom Score (CSS) is a simple, useful tool for measuring cough severity. However, there is no standard Korean version of the CSS. We developed a Korean version of the CSS and evaluated its clinical utility and validity for assessing chronic cough severity.
Methods: The..
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Rheumatology
Ileocolonoscopic findings in patients with ankylosing spondylitis: a single center retrospective
study
Soo Min Ahn, Yong-Gil Kim, Seung-Hyeon Bae, Doo-Ho Lim, Seokchan Hong, Sang Hyoung Park, Chang-Keun Lee, Bin Yoo
Korean J Intern Med. 2017;32(5):916-922. Published online August 11, 2017
Background/Aims: In some Western countries, up to 50% of patients with ankylosing spondylitis (AS) have subclinical gut inflammation. This study was conducted to evaluate the prevalence and severity of gut inflammation and to determine clinical factors associated with colonic inflammation in Korean ..
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| Letters to the editor |
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Epiphora following chemotherapy with pemetrexed in patients with advanced non-small cell lung cancer
Yun Duk Jung, Sang Bin Lee, Yun Wha Jung, Jung Sub Song, In Sook Woo
Korean J Intern Med. 2017;32(5):923-925. Published online March 18, 2017
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Metronomic chemotherapy with capecitabine for metastatic colorectal cancer in very elderly patients
Yun Hwa Jung, Won Jik Lee, Jae Ho Byeon, In Kyu Lee, Chi Wha Han, In Sook Woo
Korean J Intern Med. 2017;32(5):926-929. Published online March 10, 2016
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Gemcitabine-induced myositis in a diabetes mellitus patient on hemodialysis
June Young Chun, Jae Myung Lee, Dong Won Ahn, Jee Won Chai, Young A Kim, Kichul Shin
Korean J Intern Med. 2017;32(5):930-932. Published online February 26, 2016
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Solitary immunoglobulin G4-related inflammatory pseudotumor in the abdomen wall
Yunsuek Kim, Hae Kyung Lee, Gyuhwan Hwang, In Ho Choi, Hyun-Sook Kim
Korean J Intern Med. 2017;32(5):933-935. Published online March 12, 2016
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Hyperglycemic hyperosmolar state associated with invasive rhino-orbital aspergillosis in a
patient with end-stage renal disease
Ju Hyun Seo, Jin Ah Kim, Bomi Choi, Kyo Hee Kim, Ha Neul Park, Hannah Seok, Tae Seo Sohn
Korean J Intern Med. 2017;32(5):936-938. Published online March 10, 2016
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| Correspondences |
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Comment on “Gastric cancer and family history”
Amin Talebi Bezmin Abadi
Korean J Intern Med. 2017;32(5):939-939. Published online August 11, 2017
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| Images of interest |
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Drop metastasis from hepatocellular carcinoma after percutaneous radiofrequency ablation therapy
Sang Kuon Lee, Myeong Jun Song
Korean J Intern Med. 2017;32(5):943-944. Published online September 9, 2016
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Phlegmonous gastritis in an ankylosing spondylitis patient treated with infliximab
[corrected-article]
Bo Young Kim, Hyun-Sook Kim
Korean J Intern Med. 2017;32(5):945-946. Published online August 18, 2017
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