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Editorial
Can documented coronary vasospasm be the smoking gun in settling the etiology of sudden cardiac death?
Nam-Ho Kim, Jum Suk Ko
Korean J Intern Med. 2017;32(5):816-818. Published online August 31, 2017
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Editorial
Significance of duodenal mucosal lesions: can they be a clue to a systemic disease?
Seung Woo Lee
Korean J Intern Med. 2017;32(5):813-815. Published online August 31, 2017
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Infectious diseases / Review
Voriconazole-refractory invasive aspergillosis
Se Yoon Park, Jung-A Yoon, Sung-Han Kim
Korean J Intern Med. 2017;32(5):805-812. Published online August 24, 2017
Invasive aspergillosis (IA) is one of the most common life-threatening complications in immunocompromised patients. Voriconazole is currently the drug of choice for IA treatment. However, some patients with IA suffer clinical deterioration despite voriconazole therapy. Management of voriconazole-ref..
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Hemato-oncology / Review
Targeted therapy of ovarian cancer including immune check point inhibitor
Jin Young Kim, Chi Heum Cho, Hong Suk Song
Korean J Intern Med. 2017;32(5):798-804. Published online August 22, 2017
Epithelial ovarian cancer is the eighth most common cause of cancer-related deaths in women because most patients present with advanced stage disease at the time of diagnosis. Although cytoreductive surgery and platinum-based chemotherapy remain the gold standards of treatment, the recurrence rate o..
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Nephrology / Review
Pre-existing arterial pathologic changes affecting arteriovenous fistula patency and cardiovascular mortality in hemodialysis patients
Ja Young Lee, Young Ok Kim
Korean J Intern Med. 2017;32(5):790-797. Published online August 22, 2017
The radiocephalic arteriovenous fistula (AVF) provides optimal vascular access for hemodialysis; it has a higher long-term patency rate and fewer complications than other vascular access methods. However, the AVF has a high primary failure rate. The presence of small-diameter vessels at anastomosis ..
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Endocrinology-metabolism / Review
Oncogenes, mitochondrial metabolism, and quality control in differentiated thyroid cancer
Hyon-Seung Yi, Joon Young Chang, Koon Soon Kim, Minho Shong
Korean J Intern Med. 2017;32(5):780-789. Published online August 22, 2017
Thyroid cancer is one of the most common malignancies of endocrine organs, and its incidence rate has increased steadily over the past several decades. Most differentiated thyroid tumors derived from thyroid epithelial cells exhibit slow-growing cancers, and patients with these tumors can achieve a ..
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Cardiology / Review
Stent thrombosis and optimal duration of dual antiplatelet therapy after coronary stenting in contemporary practice
Min Soo Cho, Duk-Woo Park
Korean J Intern Med. 2017;32(5):769-779. Published online August 22, 2017
The introduction of drug-eluting stents (DES) in the practice of percutaneous coronary intervention (PCI) has substantially reduced angiographic and clinical restenosis but is associated with an increasing propensity for very late stent thrombosis (ST). Among several clinical, lesion, or procedure-r..
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Image of interest
Focal segmental glomerulosclerosis in atypical polycystic kidney disease
Eun Hui Bae, Hyunsuk Kim, Sung Sun Kim, Seong Kwon Ma, Soo Wan Kim
Korean J Intern Med. 2017;32(4):766-767. Published online January 5, 2017
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Letter to the editor
The clinical usefulness of serum procalcitonin level in patients with scrub typhus
Chang-Seop Lee, Jeong-Hwan Hwang, Jeong-Mi Lee, Jae Hoon Lee
Korean J Intern Med. 2017;32(4):761-763. Published online February 4, 2016
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Letter to the editor
Thrombophilia after total gastrectomy for morbid obesity
Sae-Bom Shin, Yu-Na Jang, Hyeon-Jeong Lee, Yun-Mi Yi, Jong-Wook Lee, Woo-Sung Min, Ki-Seong Eom
Korean J Intern Med. 2017;32(4):758-760. Published online February 25, 2016
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Letter to the editor
An isolated cardiac relapse after allogeneic hematopoietic stem cell transplantation for acute
lymphoblastic leukemia
Kiju Chang, Dae-Young Kim, Kyoo-Hyung Lee, Jooryung Huh, Joon-Won Kang, Dong Yeol Shin, Dae-Hee Kim
Korean J Intern Med. 2017;32(4):753-757. Published online February 2, 2016
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Letter to the editor
Development of Kaposi sarcoma and hemophagocytic lymphohistiocytosis associated with human herpesvirus 8 in a renal transplant recipient
Young Jae Park, Hyun Jin Bae, Ji-Yeun Chang, Chul Woo Yang, Byung Ha Chung
Korean J Intern Med. 2017;32(4):750-752. Published online February 4, 2016
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Letter to the editor
Repeated isolated bilateral coronary ostial stenosis related to the syphilitic aortitis
Sang Min Kim, Sang Yeub Lee, Ju-Hee Lee, Jang-Whan Bae, Kyung-Kuk Hwang
Korean J Intern Med. 2017;32(4):747-749. Published online June 26, 2017
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Rheumatology / Original Article
Impact of early diagnosis on functional disability in rheumatoid arthritis
Dam Kim, Chan-Bum Choi, Jiyoung Lee, Soo-Kyung Cho, Soyoung Won, So-Young Bang, Hoon-Suk Cha, Jung-Yoon Choe, Won Tae Chung, Seung-Jae Hong, Jae-Bum Jun, Young Ok Jung, Jinseok Kim, Seong-Kyu Kim, Tae-Hwan Kim, Tae-Jong Kim, Eunmi Koh, Hye-Soon Lee, Jaejoon Lee, Jisoo Lee, Sang-Heon Lee, Shin-Seok Lee, Sung Won Lee, Seung-Cheol Shim, Dae-Hyun Yoo, Bo Young Yoon, Yoon-Kyoung Sung, Sang-Cheol Bae; KORONA investigators
Korean J Intern Med. 2017;32(4):738-746. Published online September 13, 2016
Background/Aims: To determine whether early diagnosis is beneficial for functional status of various disease durations in rheumatoid arthritis (RA) patients.
Methods: A total of 4,540 RA patients were enrolled as part of the Korean Observational Study Network for Arthritis (KORONA). We defined earl..
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Infectious diseases / Original Article
In vitro antiviral activity of ribavirin against severe fever with thrombocytopenia syndrome virus
Myung Jin Lee, Kye-Hyung Kim, Jongyoun Yi, Su Jin Choi, Pyoeng Gyun Choe, Wan Beom Park, Nam Joong Kim, Myoung-don Oh
Korean J Intern Med. 2017;32(4):731-737. Published online November 30, 2016
Background/Aims: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by severe fever with thrombocytopenia syndrome virus (SFTSV), a novel bunyavirus. As yet, there is no effective antiviral therapy for SFTS. Ribavirin is a broad-spectrum antiviral agent, whic..
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Hemato-oncology / Original Article
Clinicopathological characteristics of extremely young Korean multiple myeloma patients: therapeutic implications
Junghoon Shin, Youngil Koh, Jeonghwan Youk, Miso Kim, Byung Soo Kim, Chul Won Choi, Hwa Jung Sung, Yong Park, Sung-Soo Yoon, Inho Kim
Korean J Intern Med. 2017;32(4):722-730. Published online June 26, 2017
Background/Aims: Although multiple myeloma (MM) is typically a disease of the elderly, a certain subset of extremely young patients exists. It is necessary to establish clinicopathological characteristics for this population.
Methods: We reviewed the medical records of MM patients whose age was 40 ..
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Hemato-oncology / Original Article
Myeloma prognostic index at diagnosis might be a prognostic marker in patients newly diagnosed with multiple myeloma
Dae Sik Kim, Eun Sang Yu, Ka-Won Kang, Se Ryeon Lee, Yong Park, Hwa Jung Sung, Chul Won Choi, Byung Soo Kim
Korean J Intern Med. 2017;32(4):711-721. Published online November 4, 2016
Background/Aims: The aims of this study were to identify the value of inflammatory markers as pretreatment prognostic factors for patients with multiple myeloma (MM) and to estimate the value of a prognostic index including these markers at diagnosis.
Methods: A total of 273 newly diagnosed MM pati..
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Nephrology / Original Article
The pattern of choosing dialysis modality and related mortality outcomes in Korea: a national population-based study
Hyung Jong Kim, Jung Tak Park, Seung Hyeok Han, Tae-Hyun Yoo, Hyeong-Cheon Park, Shin-Wook Kang, Kyoung Hoon Kim, Dong-Ryeol Ryu, Hyunwook Kim
Korean J Intern Med. 2017;32(4):699-710. Published online June 26, 2017
Background/Aims: Since comorbidities are major determinants of modality choice, and also interact with dialysis modality on mortality outcomes, we examined the pattern of modality choice according to comorbidities and then evaluated how such choices affected mortality in incident dialysis patients.
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Endocrinology-metabolism / Original Article
Differentiation between polycystic ovary syndrome and polycystic ovarian morphology by means of an anti-Müllerian hormone cutoff value
Do Kyeong Song, Jee-Young Oh, Hyejin Lee, Yeon-Ah Sung
Korean J Intern Med. 2017;32(4):690-698. Published online November 30, 2016
Background/Aims: Although increased serum anti-Müllerian hormone (AMH) level has been suggested to be a surrogate marker of polycystic ovarian morphology (PCOM), its association with polycystic ovary syndrome (PCOS) is controversial, and its diagnostic value has not been determined. We aimed to ob..
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