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Editorial
Body mass index at the crossroads of osteoporosis and type 2 diabetes
Jeonghoon Ha, Ki-Hyun Baek
Korean J Intern Med. 2020;35(6):1333-1335. Published online October 28, 2020
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Review
Recommendations for the management of patients with systemic rheumatic diseases during the coronavirus disease pandemic
Mi Ryoung Seo, Ji-Won Kim, Eun-Jung Park, Seung Min Jung, Yoon-Kyoung Sung, Hyungjin Kim, Gunwoo Kim, Hyun-Sook Kim, Myeung-Su Lee, Jisoo Lee, Ji An Hur, Bum Sik Chin, Joong Sik Eom, Han Joo Baek; The Korean College of Rheumatology working group
Korean J Intern Med. 2020;35(6):1317-1332. Published online September 15, 2020
Patients with systemic rheumatic diseases (SRD) are vulnerable for coronavirus disease (COVID-19). The Korean College of Rheumatology recognized the urgent need to develop recommendations for rheumatologists and other physicians to manage patients with SRD during the COVID-19 pandemic. The working g..
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Review
The clinical impact of gut microbiota in chronic kidney disease
So Mi Kim, Il han Song
Korean J Intern Med. 2020;35(6):1305-1316. Published online September 29, 2020
Gut microorganisms play critical roles in both maintaining host homeostasis and the development of diverse diseases. Gut dysbiosis, an alteration of the composition and function of gut microorganisms, is commonly seen in patients with chronic kidney disease (CKD). CKD itself contributes to a disrupt..
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Review
Renal effects of uric acid: hyperuricemia and hypouricemia
Jung Hwan Park, Yong-Il Jo, Jong-Ho Lee
Korean J Intern Med. 2020;35(6):1291-1304. Published online September 9, 2020
The prevalence of chronic kidney disease (CKD) is increasing worldwide. Although hyperuricemia has been associated with CKD in many studies, it remains controversial whether this is the cause or the result of decreased renal function. Recent observational studies of healthy populations and patients ..
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Review
Nutritional management in patients with chronic kidney disease
Sun Moon Kim, Ji Yong Jung
Korean J Intern Med. 2020;35(6):1279-1290. Published online September 23, 2020
The global prevalence of chronic kidney disease (CKD) is increasing with the aging of populations worldwide. As kidney function declines, the accumulation of metabolic waste products and excessive electrolytes can significantly impair the health of patients with CKD. As nutritional management of pat..
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Original Article / Brief Communication
What should we prepare for the next coronavirus disease 2019 outbreak? A survey on the opinions of infectious diseases specialists in South Korea
Bongyoung Kim, Se Yoon Park, Dong Sik Jung, Sook In Jung, Won Sup Oh, Shin-Woo Kim, Kyong Ran Peck, Hyun-Ha Chang; The Korean Society of Infectious Diseases
Korean J Intern Med. 2020;35(6):1270-1278. Published online September 23, 2020
Background/Aims: This study aimed to collect information on the opinions of Korean infectious disease (ID) experts on coronavirus disease 2019 (COVID-19) and related issues in preparation for a future outbreak.
Methods: A survey was conducted over the course of 5 days (from April 21 to 25, 2020), t..
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Original Article / Brief Communication
Clinical characteristics of coronavirus disease 2019 patients with diarrhea in Daegu
Min Kyu Kang, Kyeong Ok Kim, Min Cheol Kim, Joon Hyun Cho, Sung Bum Kim, Jung Gil Park, Kook Hyun Kim, See Hyung Lee, Byung Ik Jang, Tae Nyeun Kim
Korean J Intern Med. 2020;35(6):1261-1269. Published online September 23, 2020
Background/Aims: Coronavirus disease 2019 (COVID-19) can reportedly cause gastrointestinal symptoms. Therefore, we investigated the clinical characteristics of COVID-19 patients with diarrhea.
Methods: We included 118 COVID-19 patients admitted to a single hospital from February 20 to March 31, 202..
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Image of interest
Budd-Chiari syndrome presenting with abdominal wall varices
Hee Chan Yang, Hyung Ku Chon
Korean J Intern Med. 2020;35(5):1259-1260. Published online December 30, 2019
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Image of interest
Bone remodeling by checkpoint inhibitor
Hyeongjong Kim, Woo Kyun Bae
Korean J Intern Med. 2020;35(5):1258-1258. Published online September 26, 2019
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Image of interest
Various initial presentations of community onset-hypervirulent K2 serotype Klebsiella pneumoniae in healthy adult
Suhyun Oh, Gil Myeong Seong, Miyeon Kim, Keun Hwa Lee, Jeong Rae Yoo
Korean J Intern Med. 2020;35(5):1256-1257. Published online September 27, 2019
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Image of interest
Definite visualized communication of a Baker’s cyst with knee joint space and iatrogenic air content in rheumatoid arthritis patient
Hong Ki Min, Se Hee Kim, Sung Gyu Moon, Hae-Rim Kim, Sang-Heon Lee
Korean J Intern Med. 2020;35(5):1254-1255. Published online August 19, 2019
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Geriatrics / Original Article
Sarcopenia is associated with severe erectile dysfunction in older adults: a population-based cohort study
Hyungchul Park, Il-Young Jang, Minkyu Han, Heayon Lee, Hee-Won Jung, Eunju Lee, Dae Hyun Kim
Korean J Intern Med. 2020;35(5):1245-1253. Published online April 21, 2020
Background/Aims: Sarcopenia and erectile dysfunction (ED) are associat ed with poor health and quality of life in older men. We investigate the association between sarcopenia and severe ED in community-dwelling older men.
Methods: We prospectively assessed sarcopenia and ED in 519, community-dwelli..
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Rheumatology / Original Article
Hourly wages of physicians within medical fees based on the Korean relative value unit system
Hyun Ah Kim, Sung Hoon Jung, In Young Park, Seong Hun Kang
Korean J Intern Med. 2020;35(5):1238-1244. Published online December 26, 2019
Background/Aims: It is difficult to reach a social agreement on the appropriate level of compensation for professionals. This study was performed to examine the physician fee embedded in the relative value unit (RVU) system in comparison with the Korean hourly minimum wage.
Methods: The Health Insu..
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Allergy / Original Article
N-acetylcysteine decreases airway inflammation and responsiveness in asthma by modulating claudin 18 expression
Pureun-Haneul Lee, Jisu Hong, An-Soo Jang
Korean J Intern Med. 2020;35(5):1229-1237. Published online February 28, 2020
Background/Aims: N-acetylcysteine (NAC) affects signaling pathways involved in apoptosis, angiogenesis, cell growth and arrest, redox-regulated gene expression, and the inflammatory response. However, it is not known how the signal mechanism for tight junctional protein claudin (CLDN) 18 is regulate..
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Infectious diseases / Original Article
Mediation effect of herpes zoster derived by statin use on cardiovascular disease risk
Sung-Han Kim, Sung-Cheol Yun, Young-Ho Khang, Min-Chul Kim, Sun Uck Kwon, Gyung-Min Park, Young-Rak Cho, Kwang Min Lee, Moo Hyun Kim
Korean J Intern Med. 2020;35(5):1220-1228. Published online June 19, 2020
Background/Aims: Although statins are widely used to reduce the risk of cardiovascular disease (CVD) including stroke and myocardial infarction (MI), it is reported that statin use increases the incidence of herpes zoster (HZ) that is associated with increased risk of CVD. So, we evaluated the media..
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Hemato-oncology / Original Article
Cancer incidence according to the National Health Information Database in Korean patients with end-stage renal disease receiving hemodialysis
Jisun Myung, Jung Hye Choi, Joo Hark Yi, Inah Kim
Korean J Intern Med. 2020;35(5):1210-1219. Published online February 20, 2020
Background/Aims: The aim of this study was to investigate incidence, survival, and risk factors of cancer in end-stage renal disease (ESRD) patients with hemodialysis using information from the National Health Information Database (NHID).
Methods: Using the NHID, we identified ESRD patients who sta..
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Hemato-oncology / Original Article
The role of platelet function analyzer-200 in predicting perioperative bleeding risk
Eun Sang Yu, Min Ji Jeon, Ka-Won Kang, Byung-Hyun Lee, Eun Joo Kang, Yong Park, Se Ryeon Lee, Hwa Jung Sung, Chul Won Choi, Byung Soo Kim, Dae Sik Kim
Korean J Intern Med. 2020;35(5):1199-1209. Published online February 6, 2020
Background/Aims: Various preoperative screening tests, such as platelet count, prothrombin time, activated partial thromboplastin time, and bleeding time, have been widely used to evaluate the risk of bleeding during surgery. Use of platelet function analyzer (PFA)-100/200 for assessing platelet fun..
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Hemato-oncology / Original Article
Strong association between herpes simplex virus-1 and chemotherapy-induced oral mucositis in patients with hematologic malignancies
Junshik Hong, Hee-Kyung Park, Suhyun Park, Ahreum Lee, Yeon-Hee Lee, Dong-Yeop Shin, Youngil Koh, Ji-Yeob Choi, Sung-Soo Yoon, Youngnim Choi, Inho Kim
Korean J Intern Med. 2020;35(5):1188-1198. Published online September 9, 2019
Background/Aims: A link between oral cavity infections and chemotherapy-induced oral mucositis (CIOM) in patients with hematological malignancies (HMs) undergoing intensive chemotherapy (IC) or hematopoietic stem cell transplantation (HSCT) has been suggested. However, conclusive data are lacking, a..
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Nephrology / Original Article
Current findings of kidney biopsy including nephropathy associated with hypertension and diabetes mellitus in Korea
Kipyo Kim, Sang Ho Lee, Sung Woo Lee, Jung Pyo Lee, Ho Jun Chin; on behalf of the Korean GlomeruloNEphritis sTudy (KoGNET) Group
Korean J Intern Med. 2020;35(5):1173-1187. Published online August 14, 2020
Background/Aims: This study aimed to investigate long-term temporal trends and outcomes of biopsy-proven kidney diseases in a multicenter kidney biopsy cohort, focusing on hypertension and diabetes, the leading causes of end-stage kidney disease (ESKD).
Methods: The study included a total of 21,426..
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Endocrinology-metabolism / Original Article
The clinical meaning of pre- and post-ablation thyroglobulin levels at first radioiodine therapy in patients with papillary thyroid cancer
Hee Kyung Kim, Jee Hee Yoon, Jin Seong Cho, Seong Young Kwon, Su Woong Yoo, Ho-Cheol Kang
Korean J Intern Med. 2020;35(5):1164-1172. Published online July 29, 2019
Background/Aims: This study was conducted to identify prognostic factors in patients with papillary thyroid cancer (PTC) at the time of first radioactive iodine (RAI) therapy, and to evaluate the clinical value of the thyroglobulin (Tg) increase after RAI.
Methods: Serum Tg was sampled prior to (pr..
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