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A case of hemophagocytic syndrome in a patient with fulminant ulcerative colitis superinfected by cytomegalovirus
Jun Il Mun, Sung Jae Shin, Byung Hyun Yu, Jee Hoon Koo, Dong Hoon Kim, Ki Myoung Lee, Kwang Jae Lee
Korean J Intern Med. 2013;28(3):352-355. Published online May 1, 2013
Hemophagocytic syndrome (HPS) is an uncommon hematological disorder that manifests as fever, splenomegaly, and jaundice, with hemophagocytosis in the bone marrow and other tissues pathologically. Secondary HPS is associated with malignancy and infection, especially viral infection. The prevalence..
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Rheumatology
Is the frequency of metabolic syndrome higher in South Korean women with rheumatoid arthritis than in healthy subjects?
Seung-Geun Lee, Ji-Min Kim, Sun-Hee Lee, Kye-Hyung Kim, Ji-Hye Kim, Ji-Won Yi, Woo-Jin Jung, Young-Eun Park, Seong-Hu Park, Joung-Wook Lee, Seung-Hoon Baek, Jun-Hee Lee, Geun-Tae Kim
Korean J Intern Med. 2013;28(2):206-215. Published online February 27, 2013
Background/AimsTo compare the frequency of metabolic syndrome (MetS) and magnitude of insulin resistance, measured by the homeostatic model assessment of insulin resistance (HOMA-IR), between South Korean women with rheumatoid arthritis (RA) and healthy subjects, and to evalua..
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Type B insulin-resistance syndrome presenting as autoimmune hypoglycemia, associated with systemic lupus erythematosus and interstitial lung disease
Seon Mee Kang, Heung Yong Jin, Kyung Ae Lee, Ji Hyun Park, Hong Sun Baek, Tae Sun Park
Korean J Intern Med. 2013;28(1):98-102. Published online December 28, 2012
We describe an unusual case of systemic lupus erythematosus with pulmonary manifestations presenting as hypoglycemia due to anti-insulin receptor antibodies. A 38-year-old female suffered an episode of unconsciousness and was admitted to hospital where her blood glucose was found to be 18 mg/dL. ..
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Nephrology
Tissue Doppler-derived E/e' ratio as a parameter for assessing diastolic heart failure and as a predictor of mortality in patients with chronic kidney disease
Min Keun Kim, Biro Kim, Jun Young Lee, Jae Seok Kim, Byoung-Geun Han, Seung Ok Choi, Jae Won Yang
Korean J Intern Med. 2013;28(1):35-44. Published online December 28, 2012
Background/AimsDiastolic dysfunction occurs frequently in patients with chronic kidney disease (CKD) and is associated with heart failure (HF) or mortality. We investigated whether the ratio of early diastolic mitral inflow velocity to early diastolic mitral annulus velocity (..
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Cardiology
Physiologic approach for coronary intervention
William F. Fearon
Korean J Intern Med. 2013;28(1):1-7. Published online December 28, 2012
When invasively assessing coronary artery disease, the primary goal should be to determine whether the disease is causing a patient's symptoms and whether it is likely to cause future cardiac events. The presence of myocardial ischemia is our best gauge of whether a lesion is responsible for symp..
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Pelvic Bone Fractures Mimicking Bone Metastases in a Patient with Hepatitis B Virus-Associated Liver Cirrhosis and Hepatocellular Carcinoma
Dong Hyeon Lee, Eun Sun Jang, Hong Sang Oh, Kwang Hyun Chung, Eun Hyo Jin, Eu Jeong Ku, Eun Roh
Korean J Intern Med. 2012;27(4):467-469. Published online November 27, 2012
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Langerhans Cell Histiocytosis Followed by Hodgkin's Lymphoma
IK Soo Park, In Keun Park, Eun Kyoung Kim, Shin Kim, Sang Ryong Jeon, Joo Ryung Huh, Cheol Won Suh
Korean J Intern Med. 2012;27(4):459-462. Published online November 27, 2012
A 22-year-old man was referred to our institution due to lower back pain and was diagnosed with Langerhans cell histiocytosis of the thoracic and lumbar spine. The patient achieved complete remission with radiotherapy and chemotherapy. One year later, right cervical lymphadenopathy was observed a..
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Patient's Perception of Symptoms Related to Morning Activity in Chronic Obstructive Pulmonary Disease: The SYMBOL Study
Yeon Jae Kim, Byung Ki Lee, Chi Young Jung, Young June Jeon, Dae Sung Hyun, Kyung Chan Kim, Sung Ken Yu, Hye Sook Choi, Won Hyuk Shin, Kwan Ho Lee
Korean J Intern Med. 2012;27(4):426-435. Published online November 27, 2012
Background/AimsPatients with chronic obstructive pulmonary disease (COPD) experience more problematic respiratory symptoms and have more trouble performing daily activities in the morning. The aim of this study was to assess the perception of COPD symptoms related to morning a..
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Intracranial Vasculopathy in a Patient with Systemic Sclerosis: Atherosclerotic or Moyamoya-Like Disease?
Han Na Choi, Si Hye Kim, Hyun Hee Kim, Seong-Kyu Kim, Jung-Yoon Choe, Sung-Hoon Park
Korean J Intern Med. 2012;27(2):239-242. Published online May 31, 2012
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Prognosis in Patients Having Chronic Obstructive Pulmonary Disease with Significant Coronary Artery Lesion Angina
Tae Yun Park, Kyung Hee Kim, Hyun Kyoung Koo, Ji Yeon Lee, Sang-Min Lee, Jae-Jun Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Seok-Chul Yang
Korean J Intern Med. 2012;27(2):189-196. Published online May 31, 2012
Background/AimsMany studies have investigated angina and its relationship with chronic obstructive pulmonary disease (COPD). However, angina was diagnosed only by noninvasive tests or only by clinical symptoms in most of these studies. The aim of this study was to compare the ..
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The Role of Optical Coherence Tomography in Coronary Intervention
Mitsuyasu Terashima, Hideaki Kaneda, Takahiko Suzuki
Korean J Intern Med. 2012;27(1):1-12. Published online February 28, 2012
Optical coherence tomography (OCT) is an optical analog of intravascular ultrasound (IVUS) that can be used to examine the coronary arteries and has 10-fold higher resolution than IVUS. Based on polarization properties, OCT can differentiate tissue characteristics (fibrous, calcified, or lipid-ri..
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An Adult Case of Chronic Active Epstein-Barr Virus Infection with Interstitial Pneumonitis
Eun-Jeong Joo, Young Eun Ha, Dong Sik Jung, Hae Suk Cheong, Yu Mi Wi, Jae-Hoon Song, Kyong Ran Peck
Korean J Intern Med. 2011;26(4):466-469. Published online November 28, 2011
Chronic active Epstein-Barr virus (CAEBV) infection is characterized by persistent infectious mononucleosis-like symptoms, an unusual pattern of Epstein-Barr virus (EBV) antibodies, detection of the EBV genome in affected tissues or peripheral blood, and chronic illness that cannot be attributed ..
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Gender Differences in Susceptibility to Smoking among Patients with Lung Cancer
Jeong-Seon Ryu, Sang-Hoon Jeon, Jung-Soo Kim, Jung Hwan Lee, Seong Hyun Kim, Ji Taek Hong, Ju Hong Jeong, Ji Joong Jeong, Myung Dong Lee, Sang Joon Min, Hae-Seong Nam, Jae-Hwa Cho, Seung-Min Kwak, Hong Lyeol Lee, Hyun-Jung Kim
Korean J Intern Med. 2011;26(4):427-431. Published online November 28, 2011
Background/AimsTo determine whether female smokers are more or less susceptible to the detrimental pulmonary-function effects of smoking when compared to male smokers among patients with lung cancer. MethodsPack-years and pulmonary function indi..
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Sleep Disorder and Cardiovascular Risk Factors among Patients with Type 2 Diabetes Mellitus
Unjin Shim, Hyejin Lee, Jee-Young Oh, Yeon-Ah Sung
Korean J Intern Med. 2011;26(3):277-284. Published online September 13, 2011
Background/AimsSleep disorder (SD) is associated with an increased risk of cardiovascular disease and is more prevalent among individuals with type 2 diabetes mellitus. These health problems not only frequently coexist but also exacerbate each other. We conducted a cross-secti..
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Diagnostic Value of a Chimeric TSH Receptor (Mc4)-Based Bioassay for Graves' Disease
Ji In Lee, Hye Won Jang, Soo Kyoung Kim, Joon Young Choi, Ji Young Kim, Kyu Yeon Hur, Jae Hyeon Kim, Yong-Ki Min, Jae Hoon Chung, Sun Wook Kim
Korean J Intern Med. 2011;26(2):179-186. Published online June 1, 2011
Background/AimsGraves' disease (GD) is caused by thyroid-stimulating hormone receptor (TSHR) and thyroid-stimulating immunoglobulin (TSI). We used a recently introduced, technically enhanced TSI bioassay to assess its diagnostic value and determine the cut-off in patients in h..
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Two-Year Clinical Outcome after Carvedilol-Loaded Stent Implantation in Patients with Coronary Artery Disease
Hyun Kuk Kim, Young Joon Hong, Myung Ho Jeong, Weon Kim, Sung Soo Kim, Jum Suk Ko, Min Goo Lee, Doo Sun Sim, Keun Ho Park, Nam Sik Yoon, Hyun Ju Yoon, Kye Hun Kim, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Jeong Gwan Cho, Jong Chun Park, Jung Chaee Kang
Korean J Intern Med. 2011;26(1):41-46. Published online March 2, 2011
Background/AimsCarvedilol is an antioxidant that inhibits smooth muscle cell proliferation and migration. The aim of this study was to investigate the beneficial effects of carvedilol-loaded stents on 2-year clinical outcomes after stent implantation in patients with coronary ..
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Thalidomide Induced Nonspecific Interstitial Pneumonia in Patient with Relapsed Multiple Myeloma
Myung-Hee Kang, Ji-Hyun Ju, Hoon-Gu Kim, Jung Hun Kang, Kyung-Nyeo Jeon, Ho-Cheol Kim, Gyeong-Won Lee
Korean J Intern Med. 2010;25(4):447-449. Published online November 27, 2010
A 63-year-old female diagnosed with relapsed multiple myeloma visited our hospital complaining of a persistent cough. Since July 2006, she had been taking 100 mg thalidomide daily and gradually developed shortness of breath and a persistent dry cough. A chest X-ray and computed tomography showed ..
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Serum Globotriaosylceramide Assay as a Screening Test for Fabry Disease in Patients with ESRD on Maintenance Dialysis in Korea
Jeong-Yup Kim, Young-Youl Hyun, Ji-Eun Lee, Hye-Ran Yoon, Gu-Hwan Kim, Han-Wook Yoo, Seong-Tae Cho, No-Won Chun, Byoung-Chunn Jeoung, Hwa-Jung Kim, Keong-Wook Kim, Seong-Nam Kim, Yung-A Kim, Hyun-Ah Lee, Jong-Young Lee, Yung-Chun Lee, Hun-Kwan Lim, Keong-Sik Oh, Seong-Hwan Son, Beong-Hee Yu, Kyeong-So Wee, Eun-Jong Lee, Young-Ki Lee, Jung-Woo Noh, Seung-Jung Kim, Kyu-Bok Choi, Suk-Hee Yu, Heui-Jung Pyo, Young-Joo Kwon
Korean J Intern Med. 2010;25(4):415-421. Published online November 27, 2010
Background/AimsFabry disease is an X-linked recessive and progressive disease caused by α-galactosidase A (α-GaL A) deficiency. We sought to assess the prevalence of unrecognized Fabry disease in dialysis-dependent patients and the efficacy of serum globotriaosylceramide (GL..
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Correlation of Anti-Cyclic Citrullinated Antibody with Hand Joint Erosion Score in Rheumatoid Arthritis Patients
Hyun Hee Kim, JiHun Kim, Sung-Hoon Park, Seong-Kyu Kim, Ok-Dong Kim, Jung-Yoon Choe
Korean J Intern Med. 2010;25(2):201-206. Published online June 1, 2010
Background/AimsTo examine the correlation between radiological joint damage and serological parameters in early rheumatoid arthritis (RA). MethodsThis retrospective study reviewed the records of 216 patients diagnosed with RA and classified them..
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Severe Pulmonary Adverse Effects in Lymphoma Patients Treated with Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) Regimen Plus Rituximab
Kyu-Hyoung Lim, Ho-Il Yoon, Young Ae Kang, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang, Jae Ho Lee, Choon-Taek Lee, Jong Seok Lee
Korean J Intern Med. 2010;25(1):86-92. Published online February 26, 2010
Background/AimsThe aim of our study was to determine the incidence and clinical features of severe pulmonary complications in patients receiving cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or rituximab plus CHOP (R-CHOP) as the initial treatment for lymph..
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