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Rheumatology / Review
Literature review of non-pharmacological treatment for patients with axial spondyloarthritis
Jina Yeo, Mi Ryoung Seo, Jun Won Park, Yeon-Ah Lee, Ju Ho Lee, Eun Ha Kang, Seon Mi Ji, Han Joo Baek
Korean J Intern Med. 2025;40(1):40-48. Published online May 27, 2024
Axial spondyloarthritis (axSpA) is a chronic inflammatory disorder affecting the sacroiliac joints and axial spine. Along with pharmacotherapy, non-pharmacological interventions for axSpA are crucial and constitute the cornerstone of treatment. Here, we review the evidence for non-pharmacological tr..
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Rheumatology / Original Article
Characteristics of patients with psoriatic arthritis in Korea: focusing on axial involvement
Hanna Park, Ji Hyun Lee, Seung-Ki Kwok, Ji Hyeon Ju, Wan-Uk Kim, Sung-Hwan Park, Jennifer Jooha Lee
Korean J Intern Med. 2024;39(1):184-193. Published online December 8, 2023
Background/Aims: We aimed to clarify the clinical characteristics of psoriatic arthritis (PsA) in Korean patients focusing on PsA with axial involvement.
Methods: A retrospective medical chart review was performed to identify PsA patients at a single tertiary center. Cases of AS patients with psori..
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Rheumatology / Guideline
Korean treatment recommendations for patients with axial spondyloarthritis
[corrected-article]
Mi Ryoung Seo, Jina Yeo, Jun Won Park, Yeon-Ah Lee, Ju Ho Lee, Eun Ha Kang, Seon Mi Ji, Seong-Ryul Kwon, Seong-Kyu Kim, Tae-Jong Kim, Tae-Hwan Kim, Hye Won Kim, Min-Chan Park, Kichul Shin, Sang-Hoon Lee, Eun Young Lee, Hoon Suk Cha, Seung Cheol Shim, Youngim Yoon, Seung Ho Lee, Jun Hong Lim, Han Joo Baek; on behalf of the Korean Society of Spondyloarthritis Research
Korean J Intern Med. 2023;38(5):620-640. Published online July 24, 2023
We aimed to develop evidence-based recommendations for treating axial spondylarthritis (axSpA) in Korea. The development committee was constructed, key clinical questions were determined, and the evidence was searched through online databases including MEDLINE, Embase, Cochrane, KoreaMed, and Kmbase..
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Rheumatology / Original Article
The usefulness of trabecular bone score in patients with ankylosing spondylitis
Seoung Wan Nam, Yoon-Kyoung Sung, Dam Kim, Soo-Kyung Cho, Yoonah Song, Yun Young Choi, Yongjin Sim, Tae-Hwan Kim
Korean J Intern Med. 2021;36(5):1211-1220. Published online June 30, 2020
Backgrounds/Aims: This study was performed to reveal the usefulness of the trabecular bone score (TBS) in assessing bone strength in patients with ankylosing spondylitis (AS) in comparison with dual-energy X-ray absorptiometry (DXA) methods.
Methods: A total of 215 AS patients (75.8% male) were enr..
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Rheumatology / Original Article
Pregnancy outcomes in Korean women with ankylosing spondylitis
Eun Hye Park, Jung Sun Lee, Ye-Jee Kim, Seung Mi Lee, Jong Kwan Jun, Eun Bong Lee, Yong-Gil Kim
Korean J Intern Med. 2021;36(3):721-730. Published online September 26, 2019
Background/Aims: Because ankylosing spondylitis (AS) mainly affects sacroiliac joints, special attention should be given to normal labour and pregnancy outcomes. Here, we investigate pregnancy outcomes in Korean women with AS.
Methods: Based on data from the Korean Health Insurance Review and Asses..
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Rheumatology / Original Article
Liver enzyme elevation in patients with ankylosing spondylitis treated with tumor necrosis factor inhibitors: a single-center historical cohort study
Su Jin Choi, Ji Seon Oh, Seokchan Hong, Chang-Keun Lee, Bin Yoo, Yong-Gil Kim
Korean J Intern Med. 2020;35(3):723-731. Published online December 26, 2019
Background/Aims: Tumor necrosis factor inhibitors (TNFi) have been known to induce liver enzyme elevation, sometimes associated with viral reactivation or toxic hepatitis. We evaluated the incidence and risk factors of TNFi-associated liver enzyme elevation in Korean ankylosing spondylitis (AS) pati..
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Rheumatology / Original Article
Effect of biologics in the level of cytokines in the synovial fluid of patients with ankylosing spondylitis
Bon San Koo, Sungsin Jo, Eunji Kwon, Ji Hui Shin, Jin-Wuk Hur, Tae-Hwan Kim
Korean J Intern Med. 2020;35(2):465-473. Published online December 16, 2019
Background/Aims: Biologics are very effective drugs for patients with ankylosing spondylitis (AS). However, there are patients who are not responding to biologics. This study aimed to evaluate the level of tumor necrosis factor α (TNF-α), interleukin (IL)-23, and IL-17 from synovial fluid in patie..
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Guideline
The use of biological disease-modifying antirheumatic drugs for inflammatory arthritis in Korea: results of a Korean Expert Consensus
Eun-Jung Park, Hyungjin Kim, Seung Min Jung, Yoon-Kyoung Sung, Han Joo Baek, Jisoo Lee
Korean J Intern Med. 2020;35(1):41-59. Published online January 2, 2020
Biological disease-modifying antirheumatic drugs (bDMARDs) are highly effective agents for the treatment of inf lammatory arthritis; however, they also possess a potential risk for serious infection. Recently, with the rapid expansion of the bDMARDs market in Korea, reports of serious adverse events ..
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Rheumatology / Original Article
Baseline extent of damage predicts spinal radiographic progression in Korean patients with ankylosing spondylitis treated with golimumab
Jeong Seok Lee, Yeong Wook Song, Tae Hwan Kim, Won Tae Chung, Seung Geun Lee, Sung Hwan Park, Gwan Gyu Song, Dae Young Yu, Stephen Xu, Eun Young Lee
Korean J Intern Med. 2018;33(3):622-628. Published online January 20, 2017
Background/Aims: For patients with ankylosing spondylitis (AS), golimumab has consistent efficacy in controlling disease activity over 5 years but its benefit in preventing radiographic progression was less clear at 4 years. To predict radiographic progression, we analyzed the baseline characteristi..
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Rheumatology / Original Article
Drug survival of tumor necrosis factor α inhibitors in patients with ankylosing spondylitis in Korea
Hyemin Jeong, Yeong Hee Eun, In Young Kim, Hyungjin Kim, Joong Kyong Ahn, Jaejoon Lee, Eun-Mi Koh, Hoon-Suk Cha
Korean J Intern Med. 2018;33(2):407-416. Published online October 12, 2016
Background/Aims: To evaluate drug survival of the tumor necrosis factor α inhibitors (TNFi) and risk factors for the drug discontinuation in patients with ankylosing spondylitis (AS).
Methods: We retrospectively evaluated 487 AS patients at a single tertiary hospital. Among the TNFi users, drug s..
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Rheumatology / Original Article
Ileocolonoscopic findings in patients with ankylosing spondylitis: a single center retrospective
study
Soo Min Ahn, Yong-Gil Kim, Seung-Hyeon Bae, Doo-Ho Lim, Seokchan Hong, Sang Hyoung Park, Chang-Keun Lee, Bin Yoo
Korean J Intern Med. 2017;32(5):916-922. Published online August 11, 2017
Background/Aims: In some Western countries, up to 50% of patients with ankylosing spondylitis (AS) have subclinical gut inflammation. This study was conducted to evaluate the prevalence and severity of gut inflammation and to determine clinical factors associated with colonic inflammation in Korean ..
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Letter to the editor
Ankylosing spondylitis associated with primary aldosteronism in a middle-aged woman
Young Sun Suh, Hyun-Ok Kim, Yun-Hong Cheon, Wonyong Jo, Jeongmin Hong, Sang-Il Lee
Korean J Intern Med. 2017;32(2):374-377. Published online February 3, 2016
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Rheumatology / Original Article
Characteristics of hip involvement in patients with ankylosing spondylitis in Korea
Hyemin Jeong, Yeong Hee Eun, In Young Kim, Hyungjin Kim, Jaejoon Lee, Eun-Mi Koh, Hoon-Suk Cha
Korean J Intern Med. 2017;32(1):158-164. Published online March 25, 2016
Background/Aims: To evaluate the clinical course of hip arthritis and the risk factors for hip joint replacement in patients with ankylosing spondylitis (AS). Methods: In this retrospective analysis, we evaluated 488 AS patients at a single tertiary hospital. At baseline and the most recent visit to..
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Infectious diseases / Original Article
Diagnostic yield of computed tomography-guided bone biopsy and clinical outcomes of tuberculous and pyogenic spondylitis
Eun-Jeong Joo, Joon-Sup Yeom, Young Eun Ha, So Yeon Park, Chong-Suh Lee, Eun-Sang Kim, Cheol-In Kang, Doo-Ryeon Chung, Jae-Hoon Song, Kyong Ran Peck
Korean J Intern Med. 2016;31(4):762-771. Published online April 15, 2016
Background/Aims: This study aimed to evaluate the efficacy of computed tomography (CT)-guided bone biopsy for the diagnosis of spinal infection and compared the clinical outcomes between tuberculous and pyogenic spinal infections.
Methods: The retrospective cohort study included patients who receiv..
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Rheumatology / Original Article
Predictive factors of radiographic progression in ankylosing spondylitis
Hyungjin Kim, Jaejoon Lee, Joong Kyong Ahn, Jiwon Hwang, Eun-Jung Park, Hyemin Jeong, Hoon-Suk Cha, Eun-Mi Koh
Korean J Intern Med. 2015;30(3):391-397. Published online April 29, 2015
Background/Aims: The course of ankylosing spondylitis (AS) is rather variable, and the factors that predict radiographic progression remain largely obscure. In this study, we tried to determine the clinical factors and laboratory measures that are useful in predicting the radiographic progression of..
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Case Report
A rare cause of dysphagia: compression of the esophagus by an anterior cervical osteophyte due to ankylosing spondylitis
İlknur Albayrak, Sinan Bağcacı, Ali Sallı, Sami Kucuksen, Hatice Uğurlu
Korean J Intern Med. 2013;28(5):614-618. Published online August 14, 2013
Ankylosing spondylitis (AS) is a chronic inflammatory rheumatological disease affecting the axial skeleton with various extra-articular complications. Dysphagia due to a giant anterior osteophyte of the cervical spine in AS is extremely rare. We present a 48-year-old male with AS suffering from p..
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Original Article
The Clinical Usefulness of Multidetector Computed Tomography of the Sacroiliac Joint for Evaluating Spondyloarthropathies
You-Hyun Lee, Ji Young Hwang, Sun Wha Lee, Jisoo Lee
Korean J Intern Med. 2007;22(3):171-177. Published online September 30, 2007
BackgroundsDue to the low sensitivity of plain radiography, the diagnosis of early stage ankylosing spondylitis (AS) is often difficult since many patients do not meet the radiographic criteria. The objective of our study was to investigate the diagnostic value of performing m..
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Original Article
Increased Expression of Glucocorticoid Receptorβ Messenger RNA in Patients with Ankylosing Spondylitis
Chang-Keun Lee, Eun Young Lee, You-Sook Cho, Keun Ae Moon, Bin Yoo, Hee-Bom Moon
Korean J Intern Med. 2005;20(2):146-151. Published online June 30, 2005
BackgroundGlucocorticoids have been known to be less effective for treating ankylosing spondylitis (AS) patients than for treating rheumatoid arthritis (RA) patients. To elucidate the mechanisms underlying this phenomenon, we evaluated whether the glucocorticoid receptor (GR)..
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