Infectious diseases / Original Article Initial and peak serum levels of Krebs von den Lungen-6 for predicting the prognosis of patients with COVID-19 Geonui Kim, Hyeonwoo Kwon, Sang Hyun Ra, Euijin Chang, Seongman Bae, Jiwon Jung, Min Jae Kim, Yong Pil Chong, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Sung-Han Kim Korean J Intern Med. 2025;40(2):321-329.   Published online February 21, 2025 DOI: https://doi.org/10.3904/kjim.2024.161                      Background/Aims: Krebs von den Lungen-6 (KL-6) is associated with prognosis in patients with COVID-19. However, there is limited data on the correlation between the prognosis of COVID-19 and varying KL-6 levels at different time points. We investigated the optimal cutoff values of the initial and pe..

Infectious diseases / Original Article Adverse drug reactions following treatment of latent tuberculosis infection: a linked national tuberculosis surveillance with claims database Yu-Seon Jung, Sun-Young Jung, Jae-Eun Lee, Kyungeun Lee, Jae Chol Choi Korean J Intern Med. 2024;39(6):979-988.   Published online October 22, 2024 DOI: https://doi.org/10.3904/kjim.2023.557                      Background/Aims: Few real-world studies explored factors associated with latent tuberculosis infection (LTBI) treatment-related adverse drug reactions (ADRs). This study evaluate ADRs that lead to the discontinuation of LTBI treatment and identify the associated factors, including age groups and dru..

Infectious diseases / Original Article Clinical effects of non-pharmaceutical interventions for COVID-19 on other nationally notifiable infectious diseases in South Korea Hyun-Jin Lee, Beom Seuk Hwang, Seong Ho Im, Seog-Kyun Mun, Munyoung Chang Korean J Intern Med. 2024;39(5):823-832.   Published online August 13, 2024 DOI: https://doi.org/10.3904/kjim.2023.501                 Background/Aims: This study aimed to assess the impact of non-pharmaceutical interventions (NPIs) implemented during the COVID-19 pandemic on nationally notifiable infectious diseases (NNIDs) in South Korea. Methods: Long-term data on seven NNIDs from 2018 to 2021 were analyzed to identify trends a..

Infectious diseases / Image of interest Bilateral leg pain and swelling with abnormal imaging findings in a patient with voriconazole Hyeon Mu Jang, Hyeonwoo Kwon, Yunsuk Choi, Sung-Han Kim Korean J Intern Med. 2024;39(4):695-696.   Published online May 27, 2024 DOI: https://doi.org/10.3904/kjim.2024.070              Crossref 1

Infectious diseases / Original Article Impact of the coronavirus disease 2019 pandemic on the incidence of other infectious diseases in the hematology hospital in Korea Seohee Oh, Yu-Sun Sung, Mihee Jang, Yong-Jin Kim, Hyun-Wook Park, Dukhee Nho, Dong-Gun Lee, Hyeon Woo Yim, Sung-Yeon Cho Korean J Intern Med. 2024;39(3):513-523.   Published online April 23, 2024 DOI: https://doi.org/10.3904/kjim.2023.508                 Background/Aims: Since the coronavirus disease 2019 (COVID-19) outbreak, hospitals have implemented infection control measures to minimize the spread of the virus within facilities. This study aimed to investigate the impact of COVID-19 on the incidence of healthcare-associated infections (HCAIs) an..

Infectious diseases / Review Role of biomarkers in antimicrobial stewardship: physicians’ perspectives Hyeri Seok, Dae Won Park Korean J Intern Med. 2024;39(3):413-429.   Published online April 30, 2024 DOI: https://doi.org/10.3904/kjim.2023.558                 Biomarkers are playing an increasingly important role in antimicrobial stewardship. Their applications have included use in algorithms that evaluate suspected bacterial infections or provide guidance on when to start or stop antibiotic therapy, or when therapy should be repeated over a short period ..

Infectious diseases / Review Implementing antimicrobial stewardship: lessons and perspectives from a university-affiliated tertiary hospital in Korea Soo Jin Lee, Raeseok Lee, Sung-Yeon Cho, Dukhee Nho, Hye Lim Ahn, Dong-Gun Lee Korean J Intern Med. 2024;39(3):399-412.   Published online April 30, 2024 DOI: https://doi.org/10.3904/kjim.2023.504                      Antimicrobial stewardship programs (ASPs) can lower antibiotic use, decrease medical expenses, prevent the emergence of resistant bacteria, and enhance treatment for infectious diseases. This study summarizes the stepwise implementation and effects of ASPs in a single university-affiliated tertiary ..

Infectious diseases / Review Quantitative and qualitative evaluation of antimicrobial usage: the first step for antimicrobial stewardship Song Mi Moon, Bongyoung Kim, Hong Bin Kim Korean J Intern Med. 2024;39(3):383-398.   Published online April 30, 2024 DOI: https://doi.org/10.3904/kjim.2023.506              Web of Science 4    Crossref 4                 The identification of antimicrobial use patterns is essential for determining key targets for antimicrobial stewardship interventions and evaluating the effectiveness thereof. Accurately identifying antimicrobial use patterns requires quantitative evaluation, which focuses on measuring the quantity ..

Infectious diseases / Review Principles and practices of antimicrobial stewardship programs in Korea Ki Tae Kwon, Shin-Woo Kim Korean J Intern Med. 2024;39(3):373-382.   Published online April 23, 2024 DOI: https://doi.org/10.3904/kjim.2023.482                 This review addresses the escalating challenge posed by antibiotic resistance, highlighting its profound impact on global public health, including increased mortality rates and healthcare expenditures. The review focuses on the need to adopt the One Health approach to effectively manage antibiotic us..

Infectious diseases / Correspondence Duration of corticosteroid treatment in hospitalized COVID-19 patients, less is more Marko Lucijanic, Ivan Papic, Maja Ortner Hadziabdic Korean J Intern Med. 2024;39(2):360-361.   Published online February 6, 2024 DOI: https://doi.org/10.3904/kjim.2023.450              Web of Science 1    Crossref 1

Infectious diseases / Original Article The effects of remdesivir on mortality and the requirement for mechanical ventilation in patients with COVID-19: a systematic review stratified by disease severity Seungeun Ryoo, Miyoung Choi, Su-Yeon Yu, Young Kyung Yoon, Kyungmin Huh, Eun-Jeong Joo Korean J Intern Med. 2024;39(1):160-171.   Published online December 28, 2023 DOI: https://doi.org/10.3904/kjim.2023.357              Web of Science 1    Crossref 1                      Background/Aims: The effectiveness of remdesivir treatment in reducing mortality and the requirement for mechanical ventilation (MV) remains uncertain, as randomized controlled trials (RCTs) have produced conflicting results. Methods: We searched MEDLINE, EMBASE, Cochrane Central Register of Contro..

Infectious diseases / Original Article Antibiotics use patterns in end-of-life cancer patients and medical staff’s perception of antimicrobial stewardship programs Min Kwan Kwon, Kyung Hwa Jung, Sungim Choi, Hyeonjeong Kim, Chang-Yun Woo, Mingee Lee, Jeong Geun Ji, Hyo-Ju Son Korean J Intern Med. 2023;38(5):758-768.   Published online August 17, 2023 DOI: https://doi.org/10.3904/kjim.2023.160              Web of Science 4    Crossref 6                      Background/Aims: While most cancer patients with end-of-life (EOL) care receive antibiotic treatments, antibiotic use should be decided appropriately considering the benefits, side effects, resistance, and cost effects. Antimicrobial stewardship programs (ASP) are important for patients with EOL car..

Infectious diseases / Correspondence MicroCLOTS pathophysiology in coronavirus disease 2019 Samuele Renzi, Giovanni Landoni, Alberto Zangrillo, Fabio Ciceri Korean J Intern Med. 2023;38(4):570-571.   Published online September 9, 2020 DOI: https://doi.org/10.3904/kjim.2020.336              Web of Science 16    Crossref 16

Infectious diseases / Original Article Clinical significance of antinuclear antibody positivity in patients with severe coronavirus disease 2019 Soo Hyun Park, Jin Woong Suh, Kyung-Sook Yang, Jeong Yeon Kim, Sun Bean Kim, Jang Wook Sohn, Young Kyung Yoon Korean J Intern Med. 2023;38(3):417-426.   Published online April 6, 2023 DOI: https://doi.org/10.3904/kjim.2022.352              Web of Science 3    Crossref 6                 Background/Aims: This study aimed to investigate the clinical characteristics and outcomes of fluorescent antinuclear antibody (FANA)-positive patients admitted for coronavirus disease 2019 (COVID‐19) and identify FANA as a prognostic factor of mortality. Methods: This retrospective study was con..

Infectious diseases / Editorial Significance of antinuclear antibodies in patients with COVID-19 Oh-Hyun Cho Korean J Intern Med. 2023;38(3):280-281.   Published online April 28, 2023 DOI: https://doi.org/10.3904/kjim.2023.155              Web of Science 2    Crossref 2

Infectious diseases / Original Article A study on changes in lung function, neutralizing antibodies, and symptoms of adult patients hospitalized with COVID-19 Moon Seong Baek, Seong-Ho Choi, Won-Young Kim, Min-Chul Kim, Eun-Jeong Joo, Mi Suk Lee, Hyun Ah Kim, Sook In Jung, Yu Shi Nae, Bongyoung Kim, Yaeji Lim, Jin-Won Chung Korean J Intern Med. 2023;38(1):101-112.   Published online October 25, 2022 DOI: https://doi.org/10.3904/kjim.2022.050                      Background/Aims: To identify changes in symptoms and pulmonary sequelae in patients with coronavirus disease 2019 (COVID-19). Methods: Patients with COVID-19 hospitalized at seven university hospitals in Korea between February 2020 and February 2021 were enrolled, provided they had ≥ 1 outpatient..