| Reviews |
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Gastroenterology / Review
Approach to cytomegalovirus infections in patients with ulcerative colitis
[corrected-article]
Sung Chul Park, Yoon Mi Jeen, Yoon Tae Jeen
Korean J Intern Med. 2017;32(3):383-392. Published online April 20, 2017
Cytomegalovirus (CMV) reactivation is common in patients with severe ulcerative colitis (UC), and may ref lect exacerbation of mucosal inf lammation and/or administration of immunosuppressants. The question of whether CMV is an active pathogen or ‘an innocent bystander’ in the exacerbation of UC ..
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Cardiology / Review
Practical management of peripartum cardiomyopathy
Mi-Jeong Kim, Mi-Seung Shin
Korean J Intern Med. 2017;32(3):393-403. Published online April 14, 2017
Peripartum cardiomyopathy (PPCM) is an idiopathic cardiomyopathy that causes systolic heart failure (HF) in previously healthy young women. Despite latest remarkable achievement, unifying pathophysiologic mechanism is not well established. Considering close temporal relationship to pregnancy, the re..
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Endocrinology-metabolism / Review
Diabetic cardiomyopathy: where we are and where we are going
Wang-Soo Lee, Jaetaek Kim
Korean J Intern Med. 2017;32(3):404-421. Published online April 18, 2017
The global burden of diabetes mellitus and its related complications are currently increasing. Diabetes mellitus affects the heart through various mechanisms including microvascular impairment, metabolic disturbance, subcellular component abnormalities, cardiac autonomic dysfunction, and a maladapti..
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Hemato-oncology / Review
Does the efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor differ according to the type of EGFR mutation in non-small cell lung cancer?
Yong Won Choi, Jin-Hyuk Choi
Korean J Intern Med. 2017;32(3):422-428. Published online March 30, 2017
An exon 19 deletion and a L858R mutation in exon 21 of the epidermal growth factor receptor (EGFR) are the two most common mutations that predict favorable efficacy of EGFR tyrosine kinase inhibitors (TKIs) in patients with non-small cell lung cancer (NSCLC). Many retrospective and prospective studi..
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Rheumatology / Review
Infection in systemic lupus erythematosus, similarities, and differences with lupus flare
Ju-Yang Jung, Chang-Hee Suh
Korean J Intern Med. 2017;32(3):429-438. Published online April 28, 2017
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse manifestations, and its pathogenesis is unclear and complicated. Infection and SLE are similar in that they both cause inf lammatory reactions in the immune system; however, one functions to protect the body, whereas the..
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| Editorials |
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Editorial
Oxidative stress: link between hypertension and diabetes
Jun Sung Moon, Kyu Chang Won
Korean J Intern Med. 2017;32(3):439-441. Published online April 28, 2017
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Editorial
Realities of KRAS-mutated non-small cell lung cancer
Young Joo Min
Korean J Intern Med. 2017;32(3):442-442. Published online April 28, 2017
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| Original Articles |
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Gastroenterology / Original Article
Clinical implications of endoscopic ultrasonography non-traversability in patients with locoregional esophageal cancer receiving multimodality therapy
Charles J. Cho, Ho June Song, Gin Hyug Lee, Kee Don Choi, Yong-Hee Kim, Jin-Sook Ryu, Sung-Bae Kim, Jong Hoon Kim, Seung-Il Park, Hwoon-Yong Jung
Korean J Intern Med. 2017;32(3):443-451. Published online March 14, 2016
Background/Aims: Approximately 30% of esophageal cancer (EC) patients cannot complete endoscopic ultrasonography (EUS) due to malignant stricture (EUS non-traversability). This study examines clinical implications of EUS non-traversability in patients with advanced locoregional squamous EC receiving..
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Gastroenterology / Original Article
Incidence and clinical characteristics of gastroenteropancreatic neuroendocrine tumor in Korea:
a single-center experience
Chul-Hyun Lim, In Seok Lee, Byoung Yeon Jun, Jin Su Kim, Yu Kyung Cho, Jae Myung Park, Sang Young Roh, Myung Ah Lee, Sang Woo Kim, Myung-Gyu Choi
Korean J Intern Med. 2017;32(3):452-458. Published online March 29, 2016
Background/Aims: Neuroendocrine tumors (NETs) may originate from heterogeneous neuroendocrine cells. The incidence is increasing worldwide, and World Health Organization (WHO) updated its classification in 2010. We investigated clinical characteristics of gastroenteropancreatic NETs in a single cent..
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Cardiology / Original Article
Association between left ventricular function and paraprotein type in patients with multiple
myeloma
Jeong-Eun Yi, Sung-Eun Lee, Hae-Ok Jung, Chang-Ki Min, Ho-Joong Youn
Korean J Intern Med. 2017;32(3):459-468. Published online April 6, 2016
Background/Aims: Multiple myeloma (MM)–associated cardiac damage, particularly according to the type of monoclonal (M) protein has not been elucidated. We sought to investigate relationship between elevated serum M protein levels and echocardiographic indices of cardiac structure and function in pa..
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Cardiology / Original Article
Fragmented QRS and abnormal creatine kinase-MB are predictors of coronary artery disease in patients with angina and normal electrocardiographys
Jung Joo Lee, Jae Hoon Lee, Jin Woo Jeong, Jun Young Chung
Korean J Intern Med. 2017;32(3):469-477. Published online April 17, 2017
Background/Aims: Patients with symptoms of coronary artery disease (CAD) often display normal tracings or only nonspecific changes on electrocardiography (ECG). The aim of this study was to explore strategic elements of the ECG and other potential factors that are predictive of CAD in this scenario...
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Pulmonology / Original Article
Clinical significance of positive Pneumocystis jirovecii polymerase chain reaction in non-human immunodeficiency virus immunocompromised patients in a real practice
Hea Yon Lee, Hye Seon Kang, Hwa Young Lee, Chin Kook Rhee, Sook Young Lee, Seok Chan Kim, Seung Joon Kim, Yeon Joon Park, Young Kyoon Kim, Ji Young Kang
Korean J Intern Med. 2017;32(3):478-485. Published online December 13, 2016
Background/Aims: Pneumocystis jirovecii polymerase chain reaction (PCR) can be helpful in diagnosing Pneumocystis pneumonia (PCP); however it has limitations. We evaluated the prevalence of positive P. jirovecii PCR from non-human immunodeficiency virus (HIV) immunocompromised p..
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Pulmonology / Original Article
Comparing tuberculin skin test and interferon γ release assay (T-SPOT.TB) to diagnose latent tuberculosis infection in household contacts
Hyun Woo Lee, Yeon Joo Lee, Se Joong Kim, Jong Sun Park, Young-Jae Cho, Ho Il Yoon, Choon-Taek Lee, Jae-Ho Lee
Korean J Intern Med. 2017;32(3):486-496. Published online January 24, 2017
Background/Aims: The tuberculin skin test (TST) and interferon γ release assay are currently used as diagnostic tools to detect latent tuberculosis (TB) infection; however, there are inconsistencies about the degree of agreement between the tests. We aimed to evaluate the concordance rate between ..
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Endocrinology-metabolism / Original Article
Effects of valsartan and amlodipine on oxidative stress in type 2 diabetic patients with hypertension: a randomized, multicenter study
Hae Jin Kim, Seung Jin Han, Dae Jung Kim, Hak Chul Jang, Soo Lim, Sung Hee Choi, Yong Hyun Kim, Dong Hyun Shin, Se Hwa Kim, Tae Ho Kim, Yu Bae Ahn, Seung Hyun Ko, Nan Hee Kim, Ji A Seo, Ha Young Kim, Kwan Woo Lee
Korean J Intern Med. 2017;32(3):497-504. Published online December 30, 2016
Background/Aims: Oxidative stress plays an important role in the pathogenesis and progression of diabetic complications and antagonists of renin-angiotensin system and amlodipine have been reported previously to reduce oxidative stress. In this study, we compared the changes in oxidative stress mark..
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Nephrology / Original Article
Vitamin D deficiency is associated with increased risk of bacterial infections after kidney transplantation
Young-Jae Park, Sang-Un Kim, Kyung-Hee Lee, Jong-Hak Lee, Eugene Kwon, Hee-Yeon Jung, Ji-Young Choi, Jang-Hee Cho, Sun-Hee Park, Yong-Lim Kim, Hyung-Kee Kim, Seung Huh, Chan-Duck Kim
Korean J Intern Med. 2017;32(3):505-513. Published online March 25, 2016
Background/Aims: There may be an association between vitamin D levels and allograft outcomes in kidney transplant recipients (KTRs). However, few studies have been conducted to determine the association between vitamin D levels and post-transplant infections. This study investigated the impact of vi..
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Hemato-oncology / Original Article
KRAS G12C mutation as a poor prognostic marker of pemetrexed treatment in non-small cell lung cancer
Sehhoon Park, Ji-Yeon Kim, Se-Hoon Lee, Beomseok Suh, Bhumsuk Keam, Tae Min Kim, Dong-Wan Kim, Dae Seog Heo
Korean J Intern Med. 2017;32(3):514-522. Published online April 14, 2017
Background/Aims: The predictive and prognostic value of KRAS mutation and its type of mutations in non-small cell lung cancer (NSCLC) are controversial. This clinical study was designed to investigate the predictive value of KRAS mutations and its mutation types to pemetrexed and gemcitabine based t..
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Hemato-oncology / Original Article
Evaluation of the prevalence and clinical impact of toxocariasis in patients with eosinophilia of unknown origin
Hong-Beum Kim, Jun-Won Seo, Jun-Hyung Lee, Byung-Seok Choi, Sang-Gon Park
Korean J Intern Med. 2017;32(3):523-529. Published online March 30, 2017
Background/Aims: Eosinophilia has numerous diverse causes, and in many patients, it is not possible to establish the cause of eosinophilia. Recently, toxocariasis was introduced as one cause of eosinophilia. The aims of this study were to evaluate the prevalence of toxocariasis and the clinical impa..
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Infectious diseases / Original Article
The seroprevalence of Bartonella henselae in healthy adults in Korea
Hea Yoon Kwon, Jae Hyoung Im, Sun Myoung Lee, Ji Hyeon Baek, Areum Durey, Shin-Goo Park, Jae-Seung Kang, Jin-Soo Lee
Korean J Intern Med. 2017;32(3):530-535. Published online April 20, 2017
Background/Aims: Cat-scratch disease (CSD), caused by Bartonella henselae is one of the most common zoonosis. However, only several cases of B. henselae infection have been reported in Korea. This study investigated the seroprevalence of B. henselae in healthy adults and related..
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Rheumatology / Original Article
Comparative efficacy of biological agents in methotrexate-refractory rheumatoid arthritis patients: a Bayesian mixed treatment comparison
Miyoung Choi, Min Kyung Hyun, Seongmi Choi, Ha Jin Tchoe, Sung Yeon Lee, Kyeong Min Son, Min-Jeong Kim, Young Ok Jung, Hyun Ah Kim
Korean J Intern Med. 2017;32(3):536-547. Published online June 2, 2016
Background/Aims: Biological agents (biologics) targeting proinflammatory signaling have emerged as an important treatment option in rheumatoid arthritis (RA). Despite the clinical effectiveness of biologics for patients with RA who do not respond to ‘traditional’ disease-modifying anti-rheumatic ..
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| Letters to the editor |
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Letter to the editor
Lymphoid follicular proctitis resembling rectal carcinoid tumor, confirmed by endoscopic resection
Seungjun Gim, Kang Nyeong Lee, Donghoon Lee, Hye Young Lee, Ki Sul Chang, Oh Young Lee, Ho Soon Choi
Korean J Intern Med. 2017;32(3):548-551. Published online April 18, 2017
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Letter to the editor
Left ventricular thrombi after simultaneous thrombotic occlusions of multiple coronary arteries presenting acute myocardial infarction: need anticoagulant?
Hyun Joong Kim, Kyung Jin Choe, Woo-Dae Bang, Sang Jin Ha, Sang-Yong Yoo, Sangsig Cheong
Korean J Intern Med. 2017;32(3):552-554. Published online December 20, 2016
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Letter to the editor
A first case of high-flow nasal cannula oxygen therapy in patients with pulmonary tumor thrombotic microangiopathy
Hyonsoo Joo, Do-hyun Na, Jaeho Seung, Tong Yoon Kim, Gi June Min, Chin Kook Rhee
Korean J Intern Med. 2017;32(3):555-558. Published online April 18, 2017
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Letter to the editor
Spontaneous ovarian hyperstimulation syndrome in a young female subject with a lingual thyroid and primary hypothyroidism
Soo Jeong Kim, Jee Hee Yoon, Hee Kyung Kim, Ho-Cheol Kang
Korean J Intern Med. 2017;32(3):559-562. Published online August 11, 2016
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Letter to the editor
Successful desensitization of pemetrexed-induced anaphylaxis in a patient with malignant mesothelioma
Jeonghwan Youk, Hyunkyung Park, Kwang Nam Jin, Hyun Jong Moon, Min-Suk Yang, Ki Hwan Kim, Jin-Soo Kim
Korean J Intern Med. 2017;32(3):563-565. Published online November 25, 2016
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| Correspondences |
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Correspondence
Comment on “Hypogonadotrophic hypogonadism due to a mutation in the luteinizing hormone β-subunit gene”
[letter]
Hernan Valdes-Socin, Adrian F. Daly, Albert Beckers
Korean J Intern Med. 2017;32(3):566-567. Published online April 28, 2017
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Correspondence
Comment on “New therapeutic agents in diabetic nephropathy”
[letter]
Alain Gay, Peter Kolkhof
Korean J Intern Med. 2017;32(3):569-569. Published online April 28, 2017
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Correspondence
Response to comment on “New therapeutic agents in diabetic nephropathy”
Yaeni Kim, Cheol Whee Park
Korean J Intern Med. 2017;32(3):570-570. Published online April 28, 2017
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| Images of interest |
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Image of interest
Spontaneous regression of cardiac sarcoidosis resulting in total occlusion of coronary artery and ventricular aneurysm
Seok Jong Ryu, Yong Kook Hong, Sanghoon Shin, Sungjun Cho, Se-Jung Yoon
Korean J Intern Med. 2017;32(3):571-572. Published online January 5, 2017
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Image of interest
Atypical bone change of spine caused by epidural venous thrombosis in systemic lupus erythematosus with antiphospholipid syndrome
Ji Young Kim, Seunghun Lee, Yun Young Choi, Sang-Cheol Bae
Korean J Intern Med. 2017;32(3):573-574. Published online January 6, 2017
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| Erratum |
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Erratum
Two-year clinical outcomes in stable angina and acute coronary syndrome after percutaneous coronary intervention of left main coronary artery disease
Dae Young Hyun, Myung Ho Jeong, Doo Sun Sim, Yun Ah Jeong, Kyung Hoon Cho, Min Chul Kim, Hyun Kuk Kim, Hae Chang Jeong, Keun Ho Park, Young Joon Hong, Jun Han Kim, Youngkeun Ahn, Jung Chaee Kang
Korean J Intern Med. 2017;32(3):575-575. Published online April 28, 2017
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