The excision of the cervical lymph node revealed a granulomatous inflammation suggesting tuberculosis or sarcoidosis. In consideration of the patient’s cardiac mass and of his negative tuberculous polymerase chain reaction testing, cardiac sarcoidosis was suspected. The patient refused to undergo a myocardial biopsy or further treatment. After 4 months, a follow-up chest CT and TTE revealed a decrease in the size of the LV mass and a newly developed aneurysmal change in the apical portion of the LV (Fig. 1A and 1B, white arrowheads), with decreased mediastinal and cervical lymph nodes. The coronary CT showed an abrupt interruption of the left anterior descending coronary artery (white arrowheads) just before the protruding LV mass and aneurysm (black arrowheads) (Fig. 1C). Cardiac magnetic resonance imaging revealed apical aneurysm and both epicardial and endocardial involvement in the delayed hyperenhancement of the septum and the apical portion of the LV (Fig. 1D).

This case was significant in demonstrating that even self-regressing sarcoidosis can cause critical complications such as irreversible myocardial damage or consecutive fatal vascular injury. A multiple imaging approach can facilitate a more accurate and earlier diagnosis.