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Editorial
Reducing chronic obstructive pulmonary disease mortality in Korea: early diagnosis matters
Yong Il Hwang
Korean J Intern Med. 2019;34(6):1212-1214. Published online November 1, 2019
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Editorial
Potential prognostic factors for solitary hepatocellular carcinoma ≤ 5 cm after transarterial chemoembolization
Soon Young Ko, Won Hyeok Choe
Korean J Intern Med. 2019;34(6):1210-1211. Published online November 1, 2019
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Review
Rheumatic complications in cancer patients treated with immune checkpoint inhibitors
Kyung-Ann Lee, Hae-Rim Kim, So Young Yoon
Korean J Intern Med. 2019;34(6):1197-1209. Published online April 25, 2019
Immune checkpoint inhibitors (ICIs) have revolutionized anticancer therapy due to their long-term clinical benefits and immune boosting mechanisms. However, despite their consistent therapeutic effects, the use of ICIs is associated with a spectrum of adverse events due to their autoimmune and auto-..
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Review
Evaluating the recent developments in palliative chemotherapy for metastatic colorectal cancer
Sun Kyung Baek, Kyu Taek Lee, Sang Byung Bae, Sang-Cheol Lee
Korean J Intern Med. 2019;34(6):1188-1196. Published online July 29, 2019
The incidence of colorectal cancer (CRC) has increased. CRC is the third most common cancer and the fourth most common cause of cancer-related deaths in Korea. Palliative chemotherapy can be used to shrink tumors and ease symptoms caused by the cancer when cure is not possible. It is important to id..
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Review
Optimal blood pressure target and measurement in patients with chronic kidney disease
Chang Seong Kim, Hong Sang Choi, Eun Hui Bae, Soo Wan Kim, Seong Kwon Ma
Korean J Intern Med. 2019;34(6):1181-1187. Published online June 17, 2019
The prevalence rates of hypertension and chronic kidney disease (CKD) are increasing with the aging of the population. Hypertension and CKD are closely related, and hypertension with accompanying CKD is difficult to control. This difficulty controlling blood pressure (BP) can be explained by changes..
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Review
Achalasia: treatment, current status and future advances
Lee L. Swanström
Korean J Intern Med. 2019;34(6):1173-1180. Published online March 15, 2019
Achalasia was first described in the 17th century and its treatment continues to be challenging. Palliative treatment involves disruption of the lower esophageal sphincter, which can be accomplished mechanically (balloon dilation or surgical myotomy) or chemically (Botox). True surgical treatment or..
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Corrigendum
2018 Guidelines for the management of dyslipidemia in Korea
Eun-Jung Rhee, Hyeon Chang Kim, Jae Hyeon Kim, Eun Young Lee, Byung Jin Kim, Eun Mi Kim, YoonJu Song, Jeong Hyun Lim, Hae Jin Kim, Seonghoon Choi, Min Kyong Moon, Jin Oh Na, Kwang-Yeol Park, Mi Sun Oh, Sang Youb Han, Junghyun Noh, Kyung Hee Yi, Sang-Hak Lee, Soon-Cheol Hong, In-Kyung Jeong; on behalf of the Committee of Clinical Practice Guideline of Korean Society of Lipid and Atherosclerosis
Korean J Intern Med. 2019;34(5):1171-1171. Published online August 28, 2019
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Image of interest
Effects of botulinum toxin injection on systemic sclerosis-related digital ulcers
Jin-Woo Souk, Hyun-Sook Kim
Korean J Intern Med. 2019;34(5):1169-1170. Published online August 13, 2018
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Image of interest
Albers-Schönberg disease
Li-Ta Keng, Sheng-Kai Liang
Korean J Intern Med. 2019;34(5):1167-1168. Published online May 16, 2018
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Image of interest
Successful treatment of tracheoesophageal fistula using a covered esophageal stent
Jung Hun Kim, Young Koog Cheon
Korean J Intern Med. 2019;34(5):1165-1166. Published online May 16, 2018
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Rheumatology / Original Article
Impact of sleep quality on clinical features of primary Sjögren's syndrome
Sang Wan Chung, Jaehyung Hur, You-Jung Ha, Eun Ha Kang, Joon Young Hyon, Hyo-Jung Lee, Yeong Wook Song, Yun Jong Lee
Korean J Intern Med. 2019;34(5):1154-1164. Published online February 20, 2018
Background/Aims: This study aimed to investigate the inf luence of poor sleep quality on clinical features of primary Sjögren’s syndrome (pSS).
Methods: Sleep quality was cross-sectionally assessed using the Pittsburgh Sleep Quality Index (PSQI), and demographic, clinical, and laboratory data we..
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Rheumatology / Original Article
Treatment patterns of knee osteoarthritis patients in Korea
Ha-Rim Park, Soo-Kyung Cho, Seul Gi Im, Sun-Young Jung, Dalho Kim, Eun Jin Jang, Yoon-Kyoung Sung
Korean J Intern Med. 2019;34(5):1145-1153. Published online March 21, 2018
Background/Aims: To evaluate the treatment patterns of knee osteoarthritis (OA) patients in South Korea.
Methods: Using the Korean nationwide claims database, all knee OA patients in Korea during 2014 were identified by the knee OA diagnostic code (M17) or any OA diagnostic code (M15 to M19) in com..
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Infectious diseases / Original Article
Clinical and economic analysis of the 2009 H1N1 influenza pandemic among pregnant Korean women
Won Suk Choi, Min Joo Choi, Ji Yoon Noh, Joon Young Song, Woo Joo Kim, Dae Won Park, Jacob Lee, Yu Bin Seo, Ji Hyeon Baek, Sooran Choi, Hee Jin Cheong
Korean J Intern Med. 2019;34(5):1136-1144. Published online December 15, 2017
Background/Aims: Unlike Western countries, the 2009 pandemic influenza infection among pregnant women was reported as mild in a previous interim study in South Korea. However, several mortalities were reported thereafter, suggesting that nationwide data were lacking.
Methods: This case-control stud..
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Hemato-oncology / Original Article
Long-term rivaroxaban for the treatment of acute venous thromboembolism in patients with active cancer in a prospective multicenter trial
Ho-Young Yhim, Won-Il Choi, Sung-Hyun Kim, Seung-Hyun Nam, Kyoung Ha Kim, Yeung-Chul Mun, Doyeun Oh, Hun-Gyu Hwang, Keun-Wook Lee, Eun-Kee Song, Yong Shik Kwon, Soo-Mee Bang
Korean J Intern Med. 2019;34(5):1125-1135. Published online May 23, 2018
Background/Aims: Limited data are available regarding the efficacy of rivaroxaban for the treatment of cancer-associated venous thromboembolism (VTE). The aim of this study was to evaluate the effectiveness and safety of rivaroxaban for the treatment of VTE in active cancer patients.
Methods: In th..
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Hemato-oncology / Original Article
Clinical factors affecting progression-free survival with crizotinib in ALK-positive non-small cell lung cancer
Chan-Young Ock, Shin-Hye Yoo, Bhumsuk Keam, Miso Kim, Tae Min Kim, Yoon Kyung Jeon, Dong-Wan Kim, Doo Hyun Chung, Dae Seog Heo
Korean J Intern Med. 2019;34(5):1116-1124. Published online June 29, 2018
Background/Aims: Although crizotinib is standard chemotherapy for advanced anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC), clinical factors affecting progression-free survival (PFS) have not been reported. The purpose of this study was to identify clinical factor..
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Hemato-oncology / Original Article
Efficacy and safety of cisplatin and weekly docetaxel in patients with recurrent or metastatic squamous cell carcinoma of the head and neck
Moon Jin Kim, Sung Min Kim, Hyun Ae Jung, Jung Yong Hong, Won Jin Chang, Moon Ki Choi, Hye Sook Kim, Jong-Mu Sun, Keunchil Park, Myung-Ju Ahn
Korean J Intern Med. 2019;34(5):1107-1115. Published online June 20, 2018
Background/Aims: We investigated the efficacy and toxicity of a weekly schedule of docetaxel and cisplatin as a first-line treatment in patients with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC).
Methods: In this study, 18 patients with previously diagnosed R/M HNSCC we..
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Hemato-oncology / Original Article
Clinical activity of fulvestrant in metastatic breast cancer previously treated with endocrine therapy and/or chemotherapy
Mi Hwa Heo, Hee Kyung Kim, Hansang Lee, Ji-Yeon Kim, Jin-Seok Ahn, Young-Hyuck Im, Yeon Hee Park
Korean J Intern Med. 2019;34(5):1100-1106. Published online March 16, 2018
Background/Aims: We conducted a retrospective analysis of the clinical activity of fulvestrant in postmenopausal women with hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC) previously treated with endocrine therapy and/or chemotherapy..
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Nephrology / Original Article
Clinical outcomes and effects of treatment in older patients with idiopathic membranous nephropathy
Yaeni Kim, Hye Eun Yoon, Byung Ha Chung, Bum Soon Choi, Cheol Whee Park, Chul Woo Yang, Yong-Soo Kim, Yu Ah Hong, Suk Young Kim, Yoon-Kyung Chang, Hyeon Seok Hwang
Korean J Intern Med. 2019;34(5):1091-1099. Published online August 14, 2019
Background/Aims: Membranous nephropathy (MN) is the most common primary glomerular disease diagnosed in older patients. Few reports describe the clinical outcomes in older patients with idiopathic MN.
Methods: The outcomes of 135 patients with histologically proven MN were analyzed. ‘Older’ was ..
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Nephrology / Original Article
Shen-Kang protects against tacrolimus-induced renal injury
Long Ye Zhang, Jian Jin, Kang Luo, Shang Guo Piao, Hai Lan Zheng, Ji Zhe Jin, Sun Woo Lim, Bum Soon Choi, Chul Woo Yang, Can Li
Korean J Intern Med. 2019;34(5):1078-1090. Published online February 12, 2018
Background/Aims: Evidence suggests that Shen-Kang (SK), a traditional Chinese herbal medicine, protects against various types of renal injury. In this study, we evaluated whether SK treatment confers renoprotection in a rat model of chronic tacrolimus (TAC) nephropathy.
Methods: Rats were treated d..
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Endocrinology-metabolism / Original Article
Higher glucagon-to-insulin ratio is associated with elevated glycated hemoglobin levels in type 2 diabetes patients
Minyoung Lee, Minkyung Kim, Jong Suk Park, Sangbae Lee, Jihong You, Chul Woo Ahn, Kyung Rae Kim, Shinae Kang
Korean J Intern Med. 2019;34(5):1068-1077. Published online September 8, 2017
Background/Aims: The importance of α-cell dysfunction in the pathogenesis of type 2 diabetes has re-emerged recently. However, data on whether relative glucagon excess is present in clinical settings are scarce. We aimed to investigate associations between glucagon-to-insulin ratio and various meta..
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