Pulmonology / Original Article
Awareness of chronic obstructive pulmonary disease in current smokers: a nationwide survey
So Yeong Mun, Yong Il Hwang, Joo Hee Kim, Sunghoon Park, Seung Hun Jang, Jae Yong Seo, Ja Kyung Kim, Yong Bum Park, Jae Jung Shim, Ki-Suck Jung
Korean J Intern Med. 2015;30(2):191-197. Published online February 27, 2015
Background/Aims: Cigarette smoking is the most common risk factor for chronic obstructive pulmonary disease (COPD). However, few studies of the attitudes toward COPD of smokers, the group at risk of developing this condition, have been conducted. The purpose of this study was to explore the awarenes..
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Pulmonology / Original Article
Proteomic differences with and without ozone-exposure in a smoking-induced emphysema lung model
Soo-Taek Uh, So-My Koo, An Soo Jang, Sung Woo Park, Jae Sung Choi, Yong-Hoon Kim, Choon Sik Park
Korean J Intern Med. 2015;30(1):62-72. Published online December 30, 2014
Background/Aims: Acute exacerbations in chronic obstructive pulmonary disease may be related to air pollution, of which ozone is an important constituent. In this study, we investigated the protein profiles associated with ozone-induced exacerbations in a smoking-induced emphysema model.
Methods: M..
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Pulmonology / Original Article
Pleural fluid characteristics of pleuropulmonary paragonimiasis masquerading as pleural tuberculosis
Ki-Eun Hwang, Hyo-Yeop Song, Jae-Wan Jung, Su-Jin Oh, Kwon-Ha Yoon, Do-Sim Park, Eun-Taik Jeong, Hak-Ryul Kim
Korean J Intern Med. 2015;30(1):56-61. Published online December 30, 2014
Background/Aims: Pleuropulmonary paragonimiasis produces no specific symptoms or radiologic findings, allowing for the possibility of misdiagnosis. We evaluated the specific clinical and pleural fluid features of pleuropulmonary paragonimiasis masquerading as pleural tuberculosis.
Methods: We retro..
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Cardiology / Original Article
The diagnostic utility of chest computed tomography scoring for the assessment of amiodarone-induced pulmonary toxicity
In Sook Kang, Kyung Jin Kim, Yookyung Kim, Seong-Hoon Park
Korean J Intern Med. 2014;29(6):746-753. Published online October 31, 2014
Background/Aims: Amiodarone is one of the most widely used antiarrhythmic agents; however, amiodarone-induced pulmonary toxicity (APT) can be irreversible and sometimes fatal. The aim of this study was to evaluate the feasibility of chest computed tomography (CT) as a diagnostic tool for APT and to ..
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Pulmonology / Original Article
The effects of secondhand smoke on chronic obstructive pulmonary disease in nonsmoking Korean adults
Woong Jun Kim, June Seok Song, Dong Won Park, Hyun Jung Kwak, Ji-Yong Moon, Sang-Heon Kim, Jang Won Sohn, Ho Joo Yoon, Dong Ho Shin, Sung Soo Park, Tae-Hyung Kim
Korean J Intern Med. 2014;29(5):613-619. Published online August 28, 2014
Background/Aims: Smoking is widely acknowledged as the single most important risk factor for chronic obstructive pulmonary disease (COPD). However, the risk of COPD in nonsmokers exposed to secondhand smoke remains controversial. In this study, we investigated the association of secondhand smoke exp..
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Pulmonology / Original Article
Prevalence and risk factors for reflux esophagitis in patients with chronic obstructive pulmonary disease
Seo Woo Kim, Jin Hwa Lee, Yun Su Sim, Yon Ju Ryu, Jung Hyun Chang
Korean J Intern Med. 2014;29(4):466-473. Published online June 27, 2014
Background/Aims: Gastroesophageal reflux disease is one of the most common causes of chronic cough and is a potential risk factor for the exacerbation of chronic obstructive pulmonary disease (COPD). The aim of this study was to investigate the prevalence and risk factors for reflux esophagitis (RE)..
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Pulmonology / Review
Modifiers of TGF-b1 effector function as novel therapeutic targets of pulmonary fibrosis
Chang-Min Lee, Jin Wook Park, Won-Kyung Cho, Yang Zhou, Boram Han, Pyoung Oh Yoon, Jeiwook Chae, Jack A Elias, Chun Geun Lee
Korean J Intern Med. 2014;29(3):281-290. Published online April 29, 2014
Pulmonary fibrosis is a fatal progressive disease with no effective therapy. Transforming growth factor (TGF)-b1 has long been regarded as a central mediator of tissue fibrosis that involves multiple organs including skin, liver, kidney, and lung. Thus, TGF-b1 and its signaling pathways have been at..
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Rheumatology / Original Article
Meta-analysis of randomized controlled trials of bosentan for treatment of pulmonary arterial hypertension
Young Ho Lee, Gwan Gyu Song
Korean J Intern Med. 2013;28(6):701-707. Published online October 29, 2013
Background/AimsWe assessed the efficacy and safety of bosentan in patients with pulmonary arterial hypertension (PAH). MethodsWe surveyed randomized controlled trials (RCTs) of the efficacy and safety of bosentan in patients with PAH using MEDLI..
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Letter to the editor
Aortic intramural hematoma after thrombolysis in a patient with acute massive pulmonary embolism
Min Su Kim, Kyu Seop Kim, Il Soon Jung, Jae-Hyeong Park, Jin-Ok Jeong, Si Wan Choi, In-Whan Seong
Korean J Intern Med. 2013;28(5):619-621. Published online August 14, 2013
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Case Report
A case of secondary syphilis presenting as multiple pulmonary nodules
Se Joong Kim, Ju-Han Lee, Eung-Seok Lee, Il-Hwan Kim, Hyung Joo Park, Chol Shin, Je Hyeong Kim
Korean J Intern Med. 2013;28(2):231-235. Published online February 27, 2013
Syphilis is a sexually transmitted disease caused by Treponema pallidum. The prevalence of this disease has recently increased worldwide. However, pulmonary involvement in secondary syphilis is extremely rare. A 51-year-old heterosexual male patient presented with multiple pulmon..
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Letter to the editor
Pulmonary thromboembolism due to severe hyperhomocysteinemia associated with a methyltetrahydrofolate reductase mutation
Kyung Hoon Cho, Myung Ho Jeong, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Jung Chaee Kang
Korean J Intern Med. 2013;28(1):112-115. Published online December 28, 2012
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Original Article
Patient's Perception of Symptoms Related to Morning Activity in Chronic Obstructive Pulmonary Disease: The SYMBOL Study
Yeon Jae Kim, Byung Ki Lee, Chi Young Jung, Young June Jeon, Dae Sung Hyun, Kyung Chan Kim, Sung Ken Yu, Hye Sook Choi, Won Hyuk Shin, Kwan Ho Lee
Korean J Intern Med. 2012;27(4):426-435. Published online November 27, 2012
Background/AimsPatients with chronic obstructive pulmonary disease (COPD) experience more problematic respiratory symptoms and have more trouble performing daily activities in the morning. The aim of this study was to assess the perception of COPD symptoms related to morning a..
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Original Article
Prognosis in Patients Having Chronic Obstructive Pulmonary Disease with Significant Coronary Artery Lesion Angina
Tae Yun Park, Kyung Hee Kim, Hyun Kyoung Koo, Ji Yeon Lee, Sang-Min Lee, Jae-Jun Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Seok-Chul Yang
Korean J Intern Med. 2012;27(2):189-196. Published online May 31, 2012
Background/AimsMany studies have investigated angina and its relationship with chronic obstructive pulmonary disease (COPD). However, angina was diagnosed only by noninvasive tests or only by clinical symptoms in most of these studies. The aim of this study was to compare the ..
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Letter to the editor
Primary Pulmonary Plasmacytoma Presenting as Multiple Lung Nodules
Sang-Heon Kim, Tae Hyung Kim, Jang Won Sohn, Ho Joo Yoon, Dong Ho Shin, In Soon Kim, Sung Soo Park
Korean J Intern Med. 2012;27(1):111-113. Published online February 28, 2012
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Original Article
Normalization of Negative T-Wave on Electrocardiography and Right Ventricular Dysfunction in Patients with an Acute Pulmonary Embolism
Bo-Youn Choi, Dae-Gyun Park
Korean J Intern Med. 2012;27(1):53-59. Published online February 28, 2012
Background/AimsRight ventricular dysfunction (RVD) is associated with poor prognosis in patients with acute pulmonary embolism (APE). Echocardiography and computed tomography (CT)-angiography may be difficult to perform in a serial follow up, unlike electrocardiography (ECG). ..
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Case Report
Central Venous Stenosis Caused by Traction of the Innominate Vein due to a Tuberculosis-Destroyed Lung
Eun Ju Song, Dae Hyun Baek, Young-Hwan Hwang, So-Young Lee, Young-Kwon Cho, Su-Ah Sung
Korean J Intern Med. 2011;26(4):460-462. Published online November 28, 2011
We report a case of central venous stenosis due to a structural deformity caused by a tuberculosis-destroyed lung in a 65-year-old woman. The patient presented with left facial edema. She had a history of pulmonary tuberculosis, and the chest X-ray revealed a collapsed left lung. Angiography show..
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Original Article
Gender Differences in Susceptibility to Smoking among Patients with Lung Cancer
Jeong-Seon Ryu, Sang-Hoon Jeon, Jung-Soo Kim, Jung Hwan Lee, Seong Hyun Kim, Ji Taek Hong, Ju Hong Jeong, Ji Joong Jeong, Myung Dong Lee, Sang Joon Min, Hae-Seong Nam, Jae-Hwa Cho, Seung-Min Kwak, Hong Lyeol Lee, Hyun-Jung Kim
Korean J Intern Med. 2011;26(4):427-431. Published online November 28, 2011
Background/AimsTo determine whether female smokers are more or less susceptible to the detrimental pulmonary-function effects of smoking when compared to male smokers among patients with lung cancer. MethodsPack-years and pulmonary function indi..
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Original Article
Clinical Characteristics of Pulmonary Embolism with Underlying Malignancy
Ji Eun Lee, Hye-Ryoun Kim, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young-Soo Shim, Seok-Chul Yang
Korean J Intern Med. 2010;25(1):66-70. Published online February 26, 2010
Background/AimsThe risk of venous thromboembolism (VTE), which encompasses deep vein thrombosis and pulmonary embolism (PE), increases in patients with cancer. Anticancer treatment is also associated with an increased risk for VTE. We conducted this study to investigate the cl..
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Original Article
Prevalence of Depression and Anxiety in Outpatients with Chronic Airway Lung Disease
Yon Ju Ryu, Eun-Mi Chun, Jin Hwa Lee, Jung Hyun Chang
Korean J Intern Med. 2010;25(1):51-57. Published online February 26, 2010
Background/AimsPatients with chronic airway lung diseases often experience depression and anxiety, but little information is available regarding Koreans with these conditions. We thus assessed depression and anxiety in Korean patients with chronic airway lung diseases.
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Case Report
A Case of Pulmonary Langerhans' Cell Histiocytosis Mimicking Hematogenous Pulmonary Metastases
Suyeon Chon, Sun Young Kyung, Sang Pyo Lee, Jeong-Woong Park, Sung Hwan Jeong, Soo Jin Choi, Seung Yeon Ha
Korean J Intern Med. 2009;24(4):393-396. Published online November 27, 2009
A 31-year-old man presented with a dry cough and exertional dyspnea. The chest X-ray showed multiple nodular opacities throughout the entire lung field. Chest computed tomography (CT) revealed variable-sized nodules with a peribronchiolar or centrilobular distribution, some of which revealed thic..
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