KJIM :: Korean Journal of Internal Medicine

LncRNA MRAK052509 competitively adsorbs miR‐204‐3p to regulate silica dust‐induced EMT process

Liu Xuan, Jiao Zi‐ming, Tian Xue‐yan, Hu Wen‐xuan, Wang Fa‐xuan

Environmental Toxicology.2024; 39(6): 3628. CrossRef

Targeting SIRT2 in Aging-Associated Fibrosis Pathophysiology

Yongjiao Huang, Wei He, Yingting Zhang, Zhihui Zou, Longchuan Han, Jing Luo, Yunqiu Wang, Xinxin Tang, Yue Li, Yuhan Bao, Ying Huang, Xi-Dai Long, Yinkun Fu, Ming He

Taiwan Chingguan Yihau may improve post-COVID-19 respiratory complications through PI3K/AKT, HIF-1, and TNF signaling pathways revealed by network pharmacology analysis

Dung Tam Nguyen Huynh, Hien Thi Nguyen, Chien-Ming Hsieh

Th17 Cell-Derived Amphiregulin Promotes Colitis-Associated Intestinal Fibrosis Through Activation of mTOR and MEK in Intestinal Myofibroblasts

Xiaojing Zhao, Wenjing Yang, Tianming Yu, Yu Yu, Xiufang Cui, Zheng Zhou, Hui Yang, Yanbo Yu, Anthony J. Bilotta, Suxia Yao, Jimin Xu, Jia Zhou, Gregory S. Yochum, Walter A. Koltun, Austin Portolese, Defu Zeng, Jingwu Xie, Iryna V. Pinchuk, Hongjie Zhang,

Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma

Piotr Sklepkiewicz, Barbara Dymek, Michal Mlacki, Agnieszka Zagozdzon, Magdalena Salamon, Anna Maria Siwińska, Marcin Piotr Mazurkiewicz, Natalia de Souza Xavier Costa, Marzena Mazur, Thais Mauad, Adam Gołębiowski, Karolina Dzwonek, Jakub Gołąb, Zbigniew

International Journal of Molecular Sciences.2023; 24(5): 4719. CrossRef

HIF and ER stress are involved in TGFβ1-mediated wound closure of alveolar epithelial cells

Experimental Lung Research.2023; 49(1): 63. CrossRef

Cellular Localization and Distribution of TGF-β1, GDNF and PDGF-BB in the Adult Primate Central Nervous System

Hui Li, Qi-Qin Dan, Yan-Jun Chen, Li Chen, Hong-Tian Zhang, De-Zhi Mu, Ting-Hua Wang

Neurochemical Research.2023; 48(8): 2406. CrossRef

Melatonin influences the biological characteristics of keloid fibroblasts through the Erk and Smad signalling pathways

Shaobin Huang, Wuguo Deng, Yunxian Dong, Zhicheng Hu, Yi Zhang, Peng Wang, Xiaoling Cao, Miao Chen, Pu Cheng, Hailin Xu, Wenkai Zhu, Bing Tang, Jiayuan Zhu

Characteristics of Interstitial Pneumonia With Autoimmune Features (IPAF): Protocol for a Multicenter Prospective Study

Patrycja Rzepka-Wrona, Szymon Skoczyński, Wojciech J Piotrowski, Ewa Jassem, Dariusz Ziora, Adam Barczyk

JMIR Research Protocols.2023; 12: e44802. CrossRef

Animal models of silicosis: fishing for new therapeutic targets and treatments

Alicia Martínez-López, Sergio Candel, Sylwia D. Tyrkalska

European Respiratory Review.2023; 32(169): 230078. CrossRef

Genotoxicity evaluation of self-assembled-micelle inhibitory RNA-targeting amphiregulin (SAMiRNA-AREG), a novel siRNA nanoparticle for the treatment of fibrotic disease

Hyeon-Young Kim, Tae Rim Kim, Sung-Hwan Kim, In-Hyeon Kim, Youngho Ko, Sungil Yun, In-Chul Lee, Han-Oh Park, Jong-Choon Kim

Drug and Chemical Toxicology.2022; 45(5): 2109. CrossRef

The Effect of Ophiopogonin C in Ameliorating Radiation-Induced Pulmonary Fibrosis in C57BL/6 Mice: An Update Study

Blueberry Juice Attenuates Pulmonary Fibrosis via Blocking the TGF-β1/Smad Signaling Pathway

Yali Li, Liqun Wang, Qianyu Zhang, Li Tian, Cailing Gan, Hongyao Liu, Wenya Yin, Tinghong Ye

SAMiRNA Targeting Amphiregulin Alleviate Total-Body-Irradiation-Induced Renal Fibrosis

Beomseok Son, Tae Rim Kim, Jun Hong Park, Sung-Il Yun, Hanjoo Choi, Ji Woo Choi, ChanHyeok Jeon, Han-Oh Park

Ginkgolic acid improves bleomycin-induced pulmonary fibrosis by inhibiting SMAD4 SUMOylation

Lan Yu, Xiyun Bian, Chunyan Zhang, Zhouying Wu, Na Huang, Jie Yang, Wen Jin, Zongqi Feng, Dongfang Li, Xue Huo, Ting Wu, Zhongmin Jiang, Xiaozhi Liu, Dejun Sun, Premysl Mladenka

Oxidative Medicine and Cellular Longevity.2022; 2022: 1. CrossRef

Jiangtang Tongmai Prescription Reduced Diabetic Lung Injury Through SnoN and TGF-β1/Smads Signaling Pathway

Association of TNF-α, TGF-β1, amphiregulin, IL-2, and EGFR WITH pulmonary fibrosis in COVID-19

Daniel Maranatha, Helmia Hasan, Arief Bakhtiar, Anita Widyoningroem, Aryati

Journal of Infection and Public Health.2022; 15(10): 1072. CrossRef

Arecae pericarpium water extract alleviates chronic pancreatitis by deactivating pancreatic stellate cells

Bitna Kweon, Dong-Uk Kim, Jin-Young Oh, Hyuncheol Oh, Youn-Chul Kim, Yeun-Ja Mun, Gi-Sang Bae, Sung-Joo Park

Amphiregulin induces CCN2 and fibronectin expression by TGF-β through EGFR-dependent pathway in lung epithelial cells

Wun-Hao Cheng, Shih-Ya Kao, Chia-Ling Chen, Fara Silvia Yuliani, Lee-Yuan Lin, Chien-Huang Lin, Bing-Chang Chen

Protective and anti-inflammatory effect of selenium nano-particles against bleomycin-induced pulmonary injury in male rats

Rana Shahabi, Ali Anissian, Seyed Ali Javadmoosavi, Farinaz Nasirinezhad

Drug and Chemical Toxicology.2021; 44(1): 92. CrossRef

In vivo silencing of amphiregulin by a novel effective Self-Assembled-Micelle inhibitory RNA ameliorates renal fibrosis via inhibition of EGFR signals

Seung Seob Son, Soohyun Hwang, Jun Hong Park, Youngho Ko, Sung-Il Yun, Ji-Hye Lee, Beomseok Son, Tae Rim Kim, Han-Oh Park, Eun Young Lee

Targeted inhibition of β-catenin alleviates airway inflammation and remodeling in asthma via modulating the profibrotic and anti-inflammatory actions of transforming growth factor-β1

Rujie Huo, Xinli Tian, Qin Chang, Dai Liu, Chen Wang, Jingcui Bai, Runjuan Wang, Guoping Zheng, Xinrui Tian

Therapeutic Advances in Respiratory Disease.2021;[Epub] CrossRef

New Insights into Pathomechanisms and Treatment Possibilities for Lung Silicosis

International Journal of Molecular Sciences.2021; 22(8): 4162. CrossRef

RS4651 suppresses lung fibroblast activation via the TGF-β1/SMAD signalling pathway

Shirong Li, Anjian Xu, Yanmeng Li, Chunting Tan, Giuseppe La Regina, Romano Silvestri, Haoyan Wang, Wenjie Qi

European Journal of Pharmacology.2021; 903: 174135. CrossRef

Herbal Compounds in the Treatment of Pulmonary Silicosis

Cellular senescence and EMT crosstalk in bleomycin‐induced pathogenesis of pulmonary fibrosis—an in vitro analysis

Karthika Muthuramalingam, Moonjae Cho, Youngmee Kim

Cell Biology International.2020; 44(2): 477. CrossRef

Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells

Yu-An Hsu, Ching-Yao Chang, Joung-Liang Lan, Ju-Pi Li, Hui-Ju Lin, Chih-Sheng Chen, Lei Wan, Fu-Tong Liu

Journal of Biomedical Science.2020;[Epub] CrossRef

Inula japonica ameliorated bleomycin-induced pulmonary fibrosis via inhibiting soluble epoxide hydrolase

Wen-Yu Zhao, Zhi-Lin Luan, Tian-Tian Liu, Wen-Hua Ming, Xiao-Kui Huo, Hui-Lian Huang, Cheng-Peng Sun, Bao-Jing Zhang, Xiao-Chi Ma

si-SNHG5-FOXF2 inhibits TGF-β1-induced fibrosis in human primary endometrial stromal cells by the Wnt/β-catenin signalling pathway

Limin Liu, Guobin Chen, Taoliang Chen, Wenjuan Shi, Haiyan Hu, Kaijing Song, Ruichun Huang, Huihua Cai, Yuanli He

Stem Cell Research & Therapy.2020;[Epub] CrossRef

Protective effects of Rosavin on bleomycin-induced pulmonary fibrosis via suppressing fibrotic and inflammatory signaling pathways in mice

Xiaobin Xin, Dahong Yao, Ke Zhang, Shuai Han, Danni Liu, Hangyu Wang, Xueying Liu, Guoyu Li, Jian Huang, Jinhui Wang

Biomedicine & Pharmacotherapy.2019; 115: 108870. CrossRef

Biomarkers of skin and lung fibrosis in systemic sclerosis

Expert Review of Clinical Immunology.2019; 15(11): 1215. CrossRef

Dexamethasone reduces serum level of IL-17 in Bleomycin-A5-induced rats model of pulmonary fibrosis

Aihua Wang, Fengqiang Wang, Yingqiu Yin, Min Zhang, Ping Chen

Artificial Cells, Nanomedicine, and Biotechnology.2018; 46(4): 783. CrossRef

Chimaphilin inhibits human osteosarcoma cell invasion and metastasis through suppressing the TGF-β1-induced epithelial-to-mesenchymal transition markers via PI-3K/Akt, ERK1/2, and Smad signaling pathways

Canadian Journal of Physiology and Pharmacology.2018; 96(1): 1. CrossRef

Upregulated miR-29c suppresses silica-induced lung fibrosis through the Wnt/β-catenin pathway in mice

Human & Experimental Toxicology.2018; 37(9): 944. CrossRef

Autophagy and the unfolded protein response promote profibrotic effects of TGF-β1 in human lung fibroblasts

Saeid Ghavami, Behzad Yeganeh, Amir A. Zeki, Shahla Shojaei, Nicholas J. Kenyon, Sean Ott, Afshin Samali, John Patterson, Javad Alizadeh, Adel Rezaei Moghadam, Ian M. C. Dixon, Helmut Unruh, Darryl A. Knight, Martin Post, Thomas Klonisch, Andrew J. Halayk

American Journal of Physiology-Lung Cellular and Molecular Physiology.2018; 314(3): L493. CrossRef

Osthole decreases collagen I/III contents and their ratio in TGF- β 1-overexpressed mouse cardiac fibroblasts through regulating the TGF- β /Smad signaling pathway

Jin-Cheng LIU, Lei ZHOU, Feng WANG, Zong-Qi CHENG, Chen RONG

Chinese Journal of Natural Medicines.2018; 16(5): 321. CrossRef

LOXL2, a copper-dependent monoamine oxidase, activates lung fibroblasts through the TGF-β/Smad pathway

Xiaohong Wen, Yuan Liu, Yu Bai, Mingwei Li, Qiang Fu, Yi Zheng

International Journal of Molecular Medicine.2018;[Epub] CrossRef

lncRNAPCAT29 inhibits pulmonary fibrosis via the TGF‑β1‑regulated RASAL1/ERK1/2 signal pathway

Pirfenidone attenuates bleomycin-induced pulmonary fibrosis in mice by regulating Nrf2/Bach1 equilibrium

Yuan Liu, Fuai Lu, Lirong Kang, Zhihua Wang, Yongfu Wang

Bacillus Calmette-Guerin alleviates airway inflammation and remodeling by preventing TGF-β1induced epithelial–mesenchymal transition

Xinrui Tian, Xinli Tian, Rujie Huo, Qin Chang, Guoping Zheng, Yan Du, Yan Chen, Bo Niu

Human Vaccines & Immunotherapeutics.2017; 13(8): 1758. CrossRef

NLRP3 participates in the regulation of EMT in bleomycin-induced pulmonary fibrosis

Rui Tian, Yong Zhu, Jiayi Yao, Xiaoxiao Meng, Jinfeng Wang, Hui Xie, Ruilan Wang

Experimental Cell Research.2017; 357(2): 328. CrossRef

Bach1 siRNA attenuates bleomycin-induced pulmonary fibrosis by modulating oxidative stress in mice

International Journal of Molecular Medicine.2017; 39(1): 91. CrossRef

The Processes and Mechanisms of Cardiac and Pulmonary Fibrosis

Lucy A. Murtha, Michael J. Schuliga, Nishani S. Mabotuwana, Sean A. Hardy, David W. Waters, Janette K. Burgess, Darryl A. Knight, Andrew J. Boyle

Microencapsulation of Lefty-secreting engineered cells for pulmonary fibrosis therapy in mice

Hongge Ma, Shupei Qiao, Zeli Wang, Shuai Geng, Yufang Zhao, Xiaolu Hou, Weiming Tian, Xiongbiao Chen, Lifen Yao

American Journal of Physiology-Lung Cellular and Molecular Physiology.2017; 312(5): L741. CrossRef

Prevention and Therapeutic Effects and Mechanisms of Tanshinone IIA Sodium Sulfonate on Acute Liver Injury Mice Model

Lunjie Lu, Jun Zhou, Jingying Zhang, Jun Che, Yang Jiao, Yusong Zhang, Shun-Wan Chan

Evidence-Based Complementary and Alternative Medicine.2016;[Epub] CrossRef

Protective effects of ulinastatin and methylprednisolone against radiation-induced lung injury in mice

Yu Sun, Yu-Jun Du, Hui Zhao, Guo-Xing Zhang, Ni Sun, Xiu-Jiang Li

Journal of Radiation Research.2016; 57(5): 505. CrossRef

Apolipoprotein A1 Inhibits TGF-β1–Induced Epithelial-to-Mesenchymal Transition of Alveolar Epithelial Cells

Ae Rin Baek, Ji Min Lee, Hyun Jung Seo, Jong Sook Park, June Hyuk Lee, Sung Woo Park, An Soo Jang, Do Jin Kim, Eun Suk Koh, Soo Taek Uh, Yong Hoon Kim, Choon Sik Park

Tuberculosis and Respiratory Diseases.2016; 79(3): 143. CrossRef

Metformin Reduces Bleomycin-induced Pulmonary Fibrosis in Mice

Sun Mi Choi, An-Hee Jang, Hyojin Kim, Kyu Hwa Lee, Young Whan Kim

Journal of Korean Medical Science.2016; 31(9): 1419. CrossRef

Protective Effect of Ginsenoside Rg1 on Bleomycin-Induced Pulmonary Fibrosis in Rats: Involvement of Caveolin-1 and TGF-β1 Signal Pathway

Heqin Zhan, Feng Huang, Wenzhuo Ma, Zhenghang Zhao, Haifang Zhang, Chong Zhang

Biological & Pharmaceutical Bulletin.2016; 39(8): 1284. CrossRef

Delivery of RNAi Therapeutics to the Airways—From Bench to Bedside

Yingshan Qiu, Jenny Lam, Susan Leung, Wanling Liang

Celecoxib and sulindac inhibit TGF-β1-induced epithelial-mesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1

Byong-Ki Cha, Young-Suk Kim, Ki-Eun Hwang, Kyung-Hwa Cho, Seon-Hee Oh, Byoung-Ryun Kim, Hong-Young Jun, Kwon-Ha Yoon, Eun-Taik Jeong, Hak-Ryul Kim

Chitotriosidase in the Pathogenesis of Inflammation, Interstitial Lung Diseases and COPD

Allergy, Asthma & Immunology Research.2015; 7(1): 14. CrossRef

Aspidin PB, a novel natural anti-fibrotic compound, inhibited fibrogenesis in TGF-β1-stimulated keloid fibroblasts via PI-3K/Akt and Smad signaling pathways

Chemico-Biological Interactions.2015; 238: 66. CrossRef

TGF-β1-Induced Pulmonary Fibroblasts Proliferation and Differentiation Are Inhibited by Antisense Oligodeoxynucleotide of Basic Fibroblast Growth Factor

Blocking the Wnt/β-Catenin Pathway by Lentivirus-Mediated Short Hairpin RNA Targeting β-Catenin Gene Suppresses Silica-Induced Lung Fibrosis in Mice

Xin Wang, Wujing Dai, Yanrang Wang, Qing Gu, Deyi Yang, Ming Zhang

International Journal of Environmental Research and Public Health.2015; 12(9): 10739. CrossRef

The potential role of IL-33/ST2 signaling in fibrotic diseases

Journal of Leukocyte Biology.2015; 98(1): 15. CrossRef

Promising new treatment targets in patients with fibrosing lung disorders

World Journal of Clinical Cases.2014; 2(11): 668. CrossRef