Case Report
An Adult Case of Chronic Active Epstein-Barr Virus Infection with Interstitial Pneumonitis
Eun-Jeong Joo, Young Eun Ha, Dong Sik Jung, Hae Suk Cheong, Yu Mi Wi, Jae-Hoon Song, Kyong Ran Peck
Korean J Intern Med. 2011;26(4):466-469. Published online November 28, 2011
Chronic active Epstein-Barr virus (CAEBV) infection is characterized by persistent infectious mononucleosis-like symptoms, an unusual pattern of Epstein-Barr virus (EBV) antibodies, detection of the EBV genome in affected tissues or peripheral blood, and chronic illness that cannot be attributed ..
|
|
Case Report
Central Venous Stenosis Caused by Traction of the Innominate Vein due to a Tuberculosis-Destroyed Lung
Eun Ju Song, Dae Hyun Baek, Young-Hwan Hwang, So-Young Lee, Young-Kwon Cho, Su-Ah Sung
Korean J Intern Med. 2011;26(4):460-462. Published online November 28, 2011
We report a case of central venous stenosis due to a structural deformity caused by a tuberculosis-destroyed lung in a 65-year-old woman. The patient presented with left facial edema. She had a history of pulmonary tuberculosis, and the chest X-ray revealed a collapsed left lung. Angiography show..
|
|
Original Article
Gender Differences in Susceptibility to Smoking among Patients with Lung Cancer
Jeong-Seon Ryu, Sang-Hoon Jeon, Jung-Soo Kim, Jung Hwan Lee, Seong Hyun Kim, Ji Taek Hong, Ju Hong Jeong, Ji Joong Jeong, Myung Dong Lee, Sang Joon Min, Hae-Seong Nam, Jae-Hwa Cho, Seung-Min Kwak, Hong Lyeol Lee, Hyun-Jung Kim
Korean J Intern Med. 2011;26(4):427-431. Published online November 28, 2011
Background/AimsTo determine whether female smokers are more or less susceptible to the detrimental pulmonary-function effects of smoking when compared to male smokers among patients with lung cancer. MethodsPack-years and pulmonary function indi..
|
|
Original Article
Nuclear factor E2-related factor 2 Dependent Overexpression of Sulfiredoxin and Peroxiredoxin III in Human Lung Cancer
Young Sun Kim, Hye Lim Lee, Ki Bum Lee, Joo Hun Park, Wou Young Chung, Keu Sung Lee, Seung Soo Sheen, Kwang Joo Park, Sung Chul Hwang
Korean J Intern Med. 2011;26(3):304-313. Published online September 13, 2011
Background/AimsOxidative stress results in protein oxidation and is implicated in carcinogenesis. Sulfiredoxin (Srx) is responsible for the enzymatic reversal of inactivated peroxiredoxin (Prx). Nuclear factor E2-related factor 2 (Nrf2) binds to antioxidant responsive elements..
|
|
Original Article
Endoscopic Cryotherapy of Lung and Bronchial Tumors: A Systematic Review
Seon-Heui Lee, Won-Jung Choi, Sook-Whan Sung, Young-Kyoon Kim, Chi-Hong Kim, Jae-Il Zo, Kwang-Joo Park
Korean J Intern Med. 2011;26(2):137-144. Published online June 1, 2011
Background/AimsWe made a systematic review and evaluation of endoscopic cryotherapy of endobronchial tumors, investigating safety and efficacy. MethodsQualified studies regarding endoscopic cryotherapy of lung tumors were systemically evaluated ..
|
|
Case Report
Thalidomide Induced Nonspecific Interstitial Pneumonia in Patient with Relapsed Multiple Myeloma
Myung-Hee Kang, Ji-Hyun Ju, Hoon-Gu Kim, Jung Hun Kang, Kyung-Nyeo Jeon, Ho-Cheol Kim, Gyeong-Won Lee
Korean J Intern Med. 2010;25(4):447-449. Published online November 27, 2010
A 63-year-old female diagnosed with relapsed multiple myeloma visited our hospital complaining of a persistent cough. Since July 2006, she had been taking 100 mg thalidomide daily and gradually developed shortness of breath and a persistent dry cough. A chest X-ray and computed tomography showed ..
|
|
Case Report
Primary Pulmonary Biphasic Synovial Sarcoma Confirmed by Molecular Detection of a SYT-SSX2 Fusion Gene: Report of 1 Case
Jae Seok Park, Bo Ram Min, Soon Hyo Park, Kun Young Kwon, Dong-Yoon Keum, Won-Il Choi
Korean J Intern Med. 2010;25(3):331-336. Published online August 31, 2010
We experienced a case of primary pulmonary biphasic synovial sarcoma, which was confirmed by immunohistochemistry and molecular testing of SYT-SSX2 fusion transcripts. The patient was a 61-year-old man who presented with a well-defined mass in the left upper lung field on chest radiography. Left ..
|
|
Original Article
Pemetrexed versus Gefitinib versus Erlotinib in Previously Treated Patients with Non-Small Cell Lung Cancer
Junshik Hong, Sun Young Kyung, Sang Pyo Lee, Jeong Woong Park, Sung Hwan Jung, Jae-Ik Lee, Se Hoon Park, Sun Jin Sym, Jinny Park, Eun Kyung Cho, Dong Bok Shin, Jae Hoon Lee
Korean J Intern Med. 2010;25(3):294-300. Published online August 31, 2010
Background/AimsThe efficacy and safety of pemetrexed, gefitinib, and erlotinib administration in previously treated patients with non-small cell lung cancer (NSCLC) were compared. MethodsThe study patients met the following criteria: histologica..
|
|
Case Report
Two Lung Masses with Different Responses to Pemetrexed
Kwang Young Park, Jae Wook Jung, Seung Bum Nam, Ho Jin Lee, Hyo Seok Kim, Yoon Hee Choi, Jae Cheol Lee
Korean J Intern Med. 2010;25(2):213-216. Published online June 1, 2010
We described here a patient who had two lung masses. Although the two masses had the same histology and a similar good response to initial chemotherapy with gemcitabine and carboplatin, the response to pemetrexed as a second-line treatment was different after re-growth of the tumors. These two lu..
|
|
Original Article
Severe Pulmonary Adverse Effects in Lymphoma Patients Treated with Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) Regimen Plus Rituximab
Kyu-Hyoung Lim, Ho-Il Yoon, Young Ae Kang, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang, Jae Ho Lee, Choon-Taek Lee, Jong Seok Lee
Korean J Intern Med. 2010;25(1):86-92. Published online February 26, 2010
Background/AimsThe aim of our study was to determine the incidence and clinical features of severe pulmonary complications in patients receiving cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or rituximab plus CHOP (R-CHOP) as the initial treatment for lymph..
|
|
Original Article
Selectively Decreased Expression of Peroxiredoxins Induced by Silica in Pulmonary Epithelial Cells
Hye Lim Lee, Young Sun Kim, Joo Hun Park, Wou Young Chung, Kyu Sung Lee, Yoon Jung Oh, Seung Soo Sheen, Kwang Joo Park, Sung Chul Hwang
Korean J Intern Med. 2009;24(3):220-226. Published online August 26, 2009
Background/AimsPeroxiredoxin (Prx) belongs to a ubiquitous family of antioxidant enzymes that regulates many cellular processes through intracellular oxidative signal transduction pathways. Silica-induced lung damage involves reactive oxygen species (ROS) that trigger subseque..
|
|
Case Report
Successful Treatment of Small-Cell Lung Cancer With Irinotecan in a Hemodialysis Patient With End-Stage Renal Disease
Dong Min Kim, Hyun Lee Kim, Choon Hae Chung, Chi Young Park
Korean J Intern Med. 2009;24(1):73-75. Published online March 6, 2009
The prognosis of patients with end-stage renal disease has improved with advances in hemodialysis techniques. However, many patients who undergo hemodialysis suffer from various types of cancer. Limited data is available to guide clinical management of these patients who may have impaired renal f..
|
|
Original Article
EGFR and KRAS Mutations in Patients With Adenocarcinoma of the Lung
Tae Won Jang, Chul Ho Oak, Hee Kyung Chang, Soon Jung Suo, Mann Hong Jung
Korean J Intern Med. 2009;24(1):48-54. Published online March 6, 2009
Background/AimsMutations of the epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS) are important in the pathogenesis of lung cancer, and recent reports have revealed racial and geographical differences in mutation expression.
|
|
Original Article
Docetaxel Monotherapy as Second-Line Treatment for Pretreated Advanced Non-Small Cell Lung Cancer Patients
Yoon Ho Ko, Myung Ah Lee, Yeong Seon Hong, Kyung Shik Lee, Hyun Jin Park, Ie Ryung Yoo, Yeon Sil Kim, Young Kyoon Kim, Keon Hyun Jo, Young Pil Wang, Kyo Young Lee, Jin Hyoung Kang
Korean J Intern Med. 2007;22(3):178-185. Published online September 30, 2007
BackgroundSecond-line chemotherapy offers advanced non-small cell lung cancer (NSCLC) patients a small, but significant increase in survival. Docetaxel is usually administered as a 3-week schedule, yet there is significant toxicity with this therapy. Therefore, a weekly schedu..
|
|
Case Report
Pancreatitis from Metastatic Small Cell Lung Cancer: Successful Treatment with Endoscopic Intrapancreatic Stenting
Jong-Shin Woo, Kwang Ro Joo, Yong Sik Woo, Jae Young Jang, Young Woon Chang, Joung Il Lee, Rin Chang
Korean J Intern Med. 2006;21(4):256-261. Published online December 31, 2006
Lung cancer metastases can occur in almost any organ. However, metastasis of small cell lung cancer to the pancreas is rare. Moreover, not all cases present with clinically diagnosed pancreatitis. We recently treated a patient with small cell lung carcinoma that invaded the pancreatic duct causin..
|
|
Case Report
Photodynamic Therapy in Early Lung Cancer: A Report of Two Cases
Tae Won Jang, Hee Kyoo Kim, Chul Ho Oak, Mann Hong Jung
Korean J Intern Med. 2006;21(3):178-182. Published online September 30, 2006
Photodynamic therapy (PDT) that is based on the science of photochemistry has been recognized as a lung sparing local therapeutic modality that can achieve remarkable responses. It is an alternative treatment for early stage lung cancer patients who have poor lung function or multiple sites of ca..
|
|
Case Report
Pancreatic Metastasis and Obstructive Jaundice in Small Cell Lung Carcinoma
In Beom Jeong, Sun Moon Kim, Tae Hee Lee, Euyi Hyeog Im, Kyu Chan Huh, Young Woo Kang, Young Woo Choi
Korean J Intern Med. 2006;21(2):132-135. Published online June 30, 2006
Primary lung cancer frequently metastasizes to distant organs. The pancreas is a relatively infrequent site of metastasis. Furthermore, obstructive jaundice resulting from pancreatic metastasis is extremely rare. This paper examines the case of a 65-year-old woman with small cell lung cancer init..
|
|
Original Article
ThE Role of Endoscopic Surgery for Completely Obstructive Endobronchial Benign Tumor
Jae-Chol Choi, Chang Min Yu, Yon Ju Ryu, Kyeongman Jeon, Kyoung A Choi, O Jung Kwon, Hojoong Kim
Korean J Intern Med. 2006;21(1):15-19. Published online March 30, 2006
BackgroundThe improving techniques of therapeutic bronchoscopy have been replacing conventional surgery for resecting endobronchial benign tumor. However, there could be some limitation for performing bronchoscopic intervention for the patients with complete bronchial obstruct..
|
|
Case Report
Non-small Cell Lung Cancer Initially Presenting with Intracardiac Metastasis
Jung Han Kim, Joo Young Jung, Young Iee Park, Sang Ik Hwang, Chull Sung Jung, Sang Hak Lee, Chong Woo Yoo
Korean J Intern Med. 2005;20(1):86-89. Published online March 31, 2005
Intracardiac metastasis as the initial presentation of malignant neoplasm is very rare. We report here on a 64-year-old man with non-small cell lung cancer (NSCLC) initially presenting with intracardiac metastasis which was identified with 18-F fluorodeoxyglucose positron emission tomography (FDG..
|
|
|