|
Pulmonology / Original Article
Use of serology and polymerase chain reaction to detect atypical respiratory pathogens during acute exacerbation of chronic obstructive pulmonary disease
Chi Young Jung, Yeoung Hun Choe, Sang Yeub Lee, Woo Jin Kim, Jong Deog Lee, Seung Won Ra, Eu Gene Choi, Jae Seung Lee, Myung Jae Park, Ju Ock Na
Korean J Intern Med. 2018;33(5):941-951. Published online June 25, 2018
Background/Aims: To use serological and multiplex polymerase chain reaction (PCR) assays to examine sputum samples from patients experiencing acute exacerbation of chronic obstructive pulmonary disease (AECOPD) for the presence of atypical pathogens, including Mycoplasma pneumoniae, Chlamydia pneumo..
|
|
|
Pulmonology / Original Article
Clinical and molecular characteristics of pulmonary sarcomatoid carcinoma
Jae Kyeom Sim, Sang Mi Chung, Jong Hyun Choi, Jee Youn Oh, Seung Heon Lee, Je Hyeong Kim, Kyung Hoon Min, Gyu Young Hur, Jae Jeong Shim, Kyung Ho Kang, Bong Kyung Shin, Ju Han Lee, Sung Yong Lee
Korean J Intern Med. 2018;33(4):737-744. Published online February 20, 2018
Background/Aims: Pulmonary sarcomatoid carcinoma (PSC) is a poorly differentiated non-small cell lung cancer (NSCLC) that contains components of spindle or giant cells. Owing to its low prevalence, there are insufficient data regarding its clinical features, therapeutic strategies and prognosis.
Me..
|
|
|
Letter to the editor
Invasive pulmonary aspergillosis in a patient with metastatic non-small cell lung cancer after
treatment with gefitinib
Sejeong Park, Soyoung Park, Hana Choi, Ji Young Park, Hyo Seok Lim, Myung Jae Park, Si-Young Kim
Korean J Intern Med. 2018;33(1):211-213. Published online November 25, 2016
|
|
|
Pulmonology / Original Article
Factors associated with low-level physical activity in elderly patients with chronic obstructive pulmonary disease
Sang Hee Lee, Ki Uk Kim, Haejung Lee, Yun Seong Kim, Min Ki Lee, Hye-Kyung Park
Korean J Intern Med. 2018;33(1):130-137. Published online June 7, 2017
Background/Aims: In patients with chronic obstructive pulmonary disease (COPD), the extent of physical activity (PA) is correlated with disease severity and prognosis. However, factors associated with low-level PA in elderly COPD patients are not known. We assessed the levels of PA and clinical fact..
|
|
|
Pulmonology / Original Article
Epidemiological trend of pulmonary thromboembolism at a tertiary hospital in Korea
Tae Yun Park, Jae-Woo Jung, Jae Chol Choi, Jong Wook Shin, Jae Yeol Kim, Byoung Whui Choi, In Won Park
Korean J Intern Med. 2017;32(6):1037-1044. Published online March 13, 2017
Background/Aims: Despite increasing interest in pulmonary thromboembolism (PTE), data on recent trends in PTE incidence are limited. This study evaluated the recent incidence rate of PTE.
Methods: We performed a retrospective chart review of patients with PTE admitted to Chung-Ang University Hospit..
|
|
|
Pulmonology / Original Article
The activation of NLRP3-inflammsome by stimulation of diesel exhaust particles in lung tissues from emphysema model and RAW 264.7 cell line
Soo-Taek Uh, So My Koo, Yangki Kim, Kiup Kim, Sungwoo Park, An Soo Jang, Dojin Kim, Yong Hoon Kim, Choon-Sik Park
Korean J Intern Med. 2017;32(5):865-874. Published online August 18, 2017
Background/Aims: Diesel exhaust particles (DEPs) lead to elevation of reactive oxygen species, which can activate the nucleotide-binding oligomerization domain-like receptor (NLR) family members containing the pyrin domain 3 (NLRP3)-inf lammasome. In this study, we elucidated whether NLRP3 -inf lamm..
|
|
|
Pulmonology / Original Article
Long-term outcomes of surgery for chronic thromboembolic pulmonary hypertension compared
with medical therapy at a single Korean center
Soo Han Kim, Jae Won Lee, Jung-Min Ahn, Dae-Hee Kim, Jong-Min Song, Sang-Do Lee, Jae Seung Lee
Korean J Intern Med. 2017;32(5):855-864. Published online October 13, 2016
Background/Aims: Pulmonary endarterectomy (PEA) is the gold standard for treating chronic thromboembolic pulmonary hypertension (CTEPH) in Western countries. The aim of this study was to investigate the long-term outcomes of performing PEA on CTEPH patients in comparison with medical therapy at a si..
|
|
|
Letter to the editor
Acute cor pulmonale due to pulmonary tumor thrombotic microangiopathy in two patients with breast cancer
Sung Young Moon, Kang Hoon Lee, Jong Sik Lee, Hyun Suk Yang, Hong Ghi Lee, Yo Han Cho, So Young Yoon
Korean J Intern Med. 2017;32(1):190-194. Published online February 3, 2016
|
|
|
Pulmonology / Original Article
Risk factors associated with provoked pulmonary embolism
Endri Gjonbrataj, Ji Na Kim, Juarda Gjonbrataj, Hye In Jung, Hyun Jung Kim, Won-Il Choi
Korean J Intern Med. 2017;32(1):95-101. Published online April 21, 2016
Background/Aims: This study aimed to investigate the risk factors associated with provoked pulmonary embolism (PE). Methods: This retrospective cohort study included 237 patients with PE. Patients that had transient risk factors at diagnosis were classified as having provoked PE, with the remaining ..
|
|
|
Cardiology / Original Article
The predictive value of echocardiography for chronic thromboembolic pulmonary hypertension after acute pulmonary embolism in Korea
Jin Sup Park, Jinhee Ahn, Jung Hyun Choi, Hye Won Lee, Jun-Hyok Oh, Han Cheol Lee, Kwang Soo Cha, Taek Jong Hong
Korean J Intern Med. 2017;32(1):85-94. Published online April 5, 2016
Background/Aims: Chronic thromboembolic pulmonary hypertension (CTEPH) is a life-threatening complication after acute pulmonary embolism (APE) and is associated with substantial morbidity and mortality. This study aimed to investigate the incidence of CTEPH after APE in Korea and to determine echoca..
|
|
|
Pulmonology / Original Article
Usefulness of neutrophil to lymphocyte ratio in patients with chronic obstructive pulmonary
disease: a prospective observational study
Seung Jun Lee, Hyang Rae Lee, Tae Won Lee, Sunmi Ju, Sujin Lim, Se-Il Go, Jung-Wan You, Yu Ji Cho, Gyeong-Won Lee, Yi Yeong Jeong, Ho Cheol Kim, Jong Deog Lee
Korean J Intern Med. 2016;31(5):891-898. Published online March 25, 2016
Background/Aims: Neutrophil to lymphocyte ratio (NLR) in peripheral blood is a useful systemic inflammatory response biomarker. However, NLR has not been studied in patients with chronic obstructive pulmonary disease (COPD). This study was aimed to evaluate the usefulness of NLR in patients with COP..
|
|
|
Gastroenterology / Original Article
Investigation of pulmonary involvement in inflammatory bowel disease in an experimental
model of colitis
Bunyamin Aydin, Yıldıran Songur, Necla Songur, Oğuzhan Aksu, Altug Senol, I. Metin Ciris, Recep Sutcu
Korean J Intern Med. 2016;31(5):853-859. Published online August 19, 2016
Background/Aims: Inflammatory bowel disease (IBD) may also involve various extra-intestinal organs. Clinical studies have found asymptomatic/symptomatic pulmonary involvement in 1% to 6% of patients with IBD. The present study histopathologically investigated pulmonary involvement in an experimental..
|
|
|
Pulmonology / Original Article
Neuron-specific enolase as a novel biomarker reflecting tuberculosis activity and treatment
response
Sung-Jin Nam, Jee-Yeong Jeong, Tae-Won Jang, Mann-Hong Jung, Bong-Kwon Chun, Hee-Jae Cha, Chul-Ho Oak
Korean J Intern Med. 2016;31(4):694-702. Published online June 3, 2016
Background/Aims: It is not clear which tests are indicative of the activity and severity of tuberculosis (TB). This study aimed to investigate the predictive value of neuron-specific enolase (NSE) and to determine the origin of NSE in TB patients.
Methods: A single-center retrospective analysis was..
|
|
|
Pulmonology / Original Article
A prospective cohort study of latent tuberculosis in adult close contacts of active pulmonary tuberculosis patients in Korea
Sun Hyo Park, Seung Jun Lee, Yu Ji Cho, Yi Yeong Jeong, Ho Cheol Kim, Jong Deog Lee, Hee Jin Kim, Dick Menzies
Korean J Intern Med. 2016;31(3):517-524. Published online April 7, 2016
Background/Aims: The objective of this prospective study was to evaluate the diagnosis and treatment of latent tuberculosis infection (LTBI) in adult close contacts of active pulmonary tuberculosis (TB) patients in Korea.
Methods: Adult close contacts of active pulmonary TB patients were recruited ..
|
|
|
Pulmonology / Original Article
Epidemiology of chronic thromboembolic pulmonary hypertension in Korea: results from the Korean registry
So Young Park, Sang Min Lee, Jong Wook Shin, Byoung Whui Choi, Hojoong Kim, Jae Seung Lee, Sang Do Lee, Sung Soo Park, Hwa Sik Moon, Yong Bum Park
Korean J Intern Med. 2016;31(2):305-312. Published online January 29, 2016
Background/Aims: The diagnosis of chronic thromboembolic pulmonary hypertension (CTEPH) is difficult for numerous reasons and is related with a poor prognosis. In Korea, the incidence of CTEPH and its clinical features are unknown. Thus, in this study, we evaluated the clinical characteristics and o..
|
|
|
Pulmonology / Original Article
Survival benefits of warfarin in Korean patients with idiopathic pulmonary arterial hypertension
Byung Ju Kang, Yeon-Mok Oh, Sang-Do Lee, Jae Seung Lee
Korean J Intern Med. 2015;30(6):837-845. Published online October 30, 2015
Background/Aims: Idiopathic pulmonary arterial hypertension (IPAH) is an incurable disease with high mortality. Although most studies recommend anticoagulation treatment for IPAH, the benefits are uncertain, particularly in Korea, where it has not been studied. The purpose of this study was to evalu..
|
|
|
Pulmonology / Original Article
Chronic obstructive pulmonary disease (COPD) assessment test scores corresponding to modified Medical Research Council grades among COPD patients
Chang-Hoon Lee, Jinwoo Lee, Young Sik Park, Sang-Min Lee, Jae-Joon Yim, Young Whan Kim, Sung Koo Han, Chul-Gyu Yoo
Korean J Intern Med. 2015;30(5):629-637. Published online August 27, 2015
Background/Aims: In assigning patients with chronic obstructive pulmonary disease (COPD) to subgroups according to the updated guidelines of the Global Initiative for Chronic Obstructive Lung Disease, discrepancies have been noted between the COPD assessment test (CAT) criteria and modified Medical ..
|
|
|
Pulmonology / Review
Phenotype of asthma-chronic obstructive pulmonary disease overlap syndrome
Chin Kook Rhee
Korean J Intern Med. 2015;30(4):443-449. Published online June 29, 2015
Many patients with asthma or chronic obstructive pulmonary disease (COPD) have overlapping characteristics of both diseases. By spirometric definition, patients with both fixed airflow obstruction (AO) and bronchodilator reversibility or fixed AO and bronchial hyperresponsiveness can be considered t..
|
|
|
Pulmonology / Original Article
Drug-resistance pattern of Mycobacterium tuberculosis strains from patients with pulmonary and extrapulmonary tuberculosis during 2006 to 2013 in a Korean tertiary medical center
Ho Young Lee, Jin Lee, Young Seok Lee, Mi-Yeong Kim, Hyun-Kyung Lee, Young-Min Lee, Jeong Hwan Shin, Yousang Ko
Korean J Intern Med. 2015;30(3):325-334. Published online April 29, 2015
Background/Aims: We evaluated the trend in the rates of drug-resistant tuberculosis (TB) over time, as well as the difference in the drug-resistance pattern between pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) at a private referral center in South Korea.
Methods: All patients..
|
|
|
Rheumatology / Original Article
Pulmonary hypertension in systemic lupus erythematosus: an independent predictor of patient survival
Hong Ki Min, Jae Ho Lee, Seung Min Jung, Jennifer Lee, Kwi Young Kang, Seung-Ki Kwok, Ji Hyeon Ju, Kyung-Su Park, Sung-Hwan Park
Korean J Intern Med. 2015;30(2):232-241. Published online February 27, 2015
Background/Aims: We investigated whether transthoracic echocardiography-suspected pulmonary hypertension (PH) affects survival in systemic lupus erythematosus (SLE) patients and examined factors associated with PH occurrence and survival.
Methods: This retrospective single-center study included 154..
|
|
|
