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Rheumatology
Association of body composition with disease activity and disability in rheumatoid arthritis
Kyeong Min Son, Seong Hun Kang, Young Il Seo, Hyun Ah Kim
Korean J Intern Med. 2021;36(1):214-222. Published online May 15, 2020
Background/Aims: To explore the associations between body composition and pain, disease activity, and disability in rheumatoid arthritis (RA).
Methods: The study enrolled 335 patients with RA and underwent body composition measurement with an InBody analyzer. The associations of body mass index (BM..
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Infectious diseases
Ongoing outbreak of human adenovirus-associated acute respiratory illness in the Republic of Korea military, 2013 to 2018
Jae-Hoon Ko, Hyeong-taek Woo, Hong Sang Oh, Song Mi Moon, Joon Young Choi, Jeong Uk Lim, Donghoon Kim, Junsu Byun, Soon-Hwan Kwon, Daeyoun Kang, Jung Yeon Heo, Kyong Ran Peck
Korean J Intern Med. 2021;36(1):205-213. Published online September 5, 2019
Background/Aims: Human adenovirus type 55 (HAdV-55), an emerging epidemic strain, has caused several large outbreaks in the Korean military since 2014, and HAdV-associated acute respiratory illness (HAdV-ARI) has been continuously reported thereafter.
Methods: To evaluate the epidemiologic characte..
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Hemato-oncology
Treatment outcome and prognostic factors of Korean patients with chronic lymphocytic leukemia: a multicenter retrospective study
Yunsuk Choi, Jung-Hee Lee, Chul Won Jung, Jae-Cheol Jo, Jin Seok Kim, Inho Kim, Silvia Park, June-won Cheong, Sang-Hyuk Park, Sung-Yong Kim, Hong-Ghi Lee
Korean J Intern Med. 2021;36(1):194-204. Published online April 14, 2020
Background/Aims: Compared with Western countries, chronic lymphocytic leukemia (CLL) rarely occurs in Asia and has different clinical characteristics. Thus, we aimed to evaluate the clinical characteristics, treatment outcomes, and prognostic significance of Korean patients with CLL.
Methods: We re..
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Maintenance chemotherapy after 6 cycles of platinum-doublet regimen in anthracycline-and taxane-pretreated metastatic breast cancer
Eun Kyo Joung, Ji Hyun Yang, Sooeun Oh, Se Jun Park, Jieun Lee
Korean J Intern Med. 2021;36(1):182-193. Published online February 28, 2020
Background/Aims: Sequential monotherapy is recommended for anthracycline-and taxane-resistant metastatic breast cancer (MBC), but combination chemotherapy is considered in patients with visceral crisis. Cisplatin-doublet chemotherapy is a combination regimen for MBC, but prolonged treatment is chall..
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Role of concurrent chemoradiation on locally advanced unresectable adenoid cystic carcinoma
Hyerim Ha, Bhumsuk Keam, Chan-Young Ock, Tae Min Kim, Jin Ho Kim, Eun-Jae Chung, Seong Keun Kwon, Soon-Hyun Ahn, Hong-Gyun Wu, Myung-Whun Sung, Dae Seog Heo
Korean J Intern Med. 2021;36(1):175-181. Published online March 30, 2020
Background/Aims: Adenoid cystic carcinoma (ACC) is a rare salivary gland tumor characterized by indolence, with a high rate of local recurrence and distant metastasis. This study aimed to investigate the effect of concurrent chemoradiation (CCRT) on locally advanced unresectable ACC.
Methods: We re..
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Nephrology
Usefulness of BK virus-specific interferon-γ enzyme-linked immunospot assay for predicting the outcome of BK virus infection in kidney transplant recipients
Hyunjoo Bae, Do Hyun Na, Ji-Yeun Chang, Ki Hyun Park, Ji Won Min, Eun Jeong Ko, Hyeyoung Lee, Chul Woo Yang, Byung Ha Chung, Eun-Jee Oh
Korean J Intern Med. 2021;36(1):164-174. Published online April 3, 2020
Background/Aims: To investigate if BK virus (BKV)-specific T cell immunity measured by an interferon-γ enzyme-linked immunospot (ELISPOT) assay can predict the outcome of BK virus infection in kidney transplant recipients (KTRs). Methods: We included 68 KTRs with different viremia status (no virem..
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Endocrinology-metabolism
Incidence and risk factors for osteoporotic fractures in patients with systemic lupus erythematosus versus matched controls
Chang Seong Kim, Kyung-Do Han, Jin Hyung Jung, Hong Sang Choi, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
Korean J Intern Med. 2021;36(1):154-163. Published online June 26, 2019
Background/Aims: Despite recent improvements in the quality of life of patients with systemic lupus erythematosus (SLE), osteoporosis, and osteoporotic fractures are one of the major complications of SLE. Furthermore, limited data are available on the incidence and predictor of osteoporotic fracture..
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Pulmonology
Effect of corticosteroid therapy in the early phase of acute respiratory distress syndrome: a propensity-matched cohort study
Moon Seong Baek, Yunkyoung Lee, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh, Jin Won Huh
Korean J Intern Med. 2021;36(1):145-153. Published online March 5, 2020
Background/Aims: It is unclear whether corticosteroid use in patients with acute respiratory distress syndrome (ARDS) improves survival. This study aimed to investigate whether the administration of corticosteroids to patients in the early phase of moderate to severe ARDS is associated with improved..
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Validity and reliability of the Korean version of the Wisconsin Smoking Withdrawal Scale
Hyonsoo Joo, Hyeon Hui Kang, Hwa Sik Moon, Sang Haak Lee
Korean J Intern Med. 2021;36(1):135-144. Published online February 24, 2020
Background/Aims: This study evaluated the validity and reliability of the Korean version of the Wisconsin Smoking Withdrawal Scale (WSWS-K) for use in clinical practice and research on Korean smokers.
Methods: The Wisconsin Smoking Withdrawal Scale was translated into Korean and then back-translate..
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Cardiology
Comparison of calcium-channel blockers for long-term clinical outcomes in patients with vasospastic angina
Sung Eun Kim, Sang-Ho Jo, Seung Hwan Han, Kwan Yong Lee, Sung Ho Her, Min-Ho Lee, Won-Woo Seo, Seong-Sik Cho, Sang Hong Baek
Korean J Intern Med. 2021;36(1):124-134. Published online February 24, 2020
Background/Aims: Calcium channel blockers (CCBs) are the most widely prescribed medication for patients with vasospastic angina (VA). However, few studies have compared the prognosis of VA patients who are prescribed different CCBs.
Methods: We enrolled 2,960 patients who received provocation test ..
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Comparative occurrence of ischemic stroke with the rhythm versus rate control strategy in a national prospective cohort of atrial fibrillation
Jae Guk Kim, Young Soo Lee, Ki-Woon Kang, Eue-Keun Choi, Myung-Jin Cha, Jung-Myung Lee, Jin-Bae Kim, Junbeom Park, Jin-Kyu Park, Tae-Hoon Kim, Jae-Sun Uhm, Jaemin Shim, Jun Kim, HyungWook Park, Changsoo Kim, Boyoung Joung
Korean J Intern Med. 2021;36(1):114-123. Published online October 14, 2019
Background/Aims: Comparative occurrence of ischemic stroke for rhythm versus rate control strategy in patients with non-valvular atrial fibrillation (NVAF) is still inconclusive. The purpose of this study was to investigate whether the rhythm control strategy is associated with a lower risk of isch..
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Clinical characteristics of spontaneous coronary artery dissection in young female patients with acute myocardial infarction in Korea
Yongcheol Kim, Xiongyi Han, Youngkeun Ahn, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Myung Ho Jeong
Korean J Intern Med. 2021;36(1):106-113. Published online July 18, 2019
Background/Aims: We aimed to evaluate the prevalence, characteristics, and clinical outcomes of spontaneous coronary artery dissection (SCAD) in young female patients with acute myocardial infarction (AMI).
Methods: We identified 8,250 patients diagnosed with AMI who underwent coronary angiogram fr..
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Gastroenterology
Risk for metabolic syndrome in the population with visceral fat area measured by bioelectrical impedance analysis
Han Ho Jeon, Yong Kang Lee, Dong Hyun Kim, Haeyong Pak, Sang Yun Shin, Jeong Hun Seo
Korean J Intern Med. 2021;36(1):97-105. Published online April 29, 2020
Background/Aims: To investigate whether visceral fat area (VFA) measured by bioelectric impedance analysis (BIA) was associated with metabolic syndrome in subjects with and without obesity.
Methods: A total 23,202 participants who underwent medical check-ups were assessed. Participants were stratif..
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The quality of non-alcoholic fatty liver disease information resources for patients on the internet in Korea
In Tae So, Yoo Jin Lee, Hye In Jung, Jae Seok Hwang, Byoung Kuk Jang
Korean J Intern Med. 2021;36(1):86-96. Published online July 31, 2019
Background/Aims: Many patients uses the internet to obtain information about their diseases. However, there is increasing concern regarding the quality of internet information. Thus, we aimed to systematically evaluate the quality of websites containing educational information about non-alcoholic fat..
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Role of tenofovir disoproxil fumarate in prevention of perinatal transmission of hepatitis B virus from mother to child: a systematic review and meta-analysis
Young-Sun Lee, Ha Seok Lee, Ji Hoon Kim, Sung Won Chang, Myung Han Hyun, Haein Bak, Sehwa Kim, Min-jin Lee, Chan Uk Lee, Young Kul Jung, Yeon Seok Seo, Hyung Joon Yim, Jong Eun Yeon, Soon Ho Um, Kwan Soo Byun
Korean J Intern Med. 2021;36(1):76-85. Published online December 31, 2019
Background/Aims: To prevent the perinatal transmission of hepatitis B virus (HBV) from mother to child, administration of an antiviral agent during pregnancy has been attempted in women who are either hepatitis B e antigen positive or have a high viral load. In this systematic review and meta-analys..
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Gastroprotective effects of irsogladine maleate on ethanol/hydrochloric acid induced gastric ulcers in mice
Seong Chun Kwon, Ji Hoon Kim
Korean J Intern Med. 2021;36(1):67-75. Published online December 20, 2019
Background/Aims: This study was conducted to investigate the inhibitory effect of irsogladine maleate (IM) on gastric ulcers induced by ethanol and hydrochloric acid (HCl).
Methods: Mice were pretreated with IM for 1 hours before ulcer induction. Gastric ulcers were induced by oral administration o..
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A new perspective on calcium channel blockers in vasospastic angina
Hack-Lyoung Kim
Korean J Intern Med. 2021;36(1):63-64. Published online January 1, 2021
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