Gastroenterology
Factors influencing occurrence of metachronous gastric cancer after endoscopic resection: a systematic review and meta-analysis
Younghee Choe, Jae Myung Park, Joon Sung Kim, Yu Kyung Cho, Byung-Wook Kim, Myung-Gyu Choi
Korean J Intern Med. 2023;38(6):831-843. Published online November 1, 2023
Background/Aims: Metachronous gastric cancer (MGC) can occur after endoscopic resection for gastric cancer. Further studies on factors other than Helicobacter pylori infection are needed. This systematic review and meta-analysis aimed to evaluate risk factors for metachronous recurrence of en..
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Infectious diseases
Comparison of the rapidity of SARS-CoV-2 immune responses between primary and booster vaccination for COVID-19
Ji Yeun Kim, Ji-Soo Kwon, Hye Hee Cha, So Yun Lim, Seongman Bae, Sung-Han Kim
Korean J Intern Med. 2022;37(6):1234-1240. Published online October 11, 2022
Background/Aims: The rapidity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific memory B or T cell response in vaccinated individuals is important for our understanding of immunopathogenesis of coronavirus disease 2019 (COVID-19). We therefore compared the timing of adequate ..
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Endocrinology-metabolism
Clinical features and signaling effects of RET D631Y variant multiple endocrine neoplasia type 2 (MEN2)
Ji-young Lee, Su Yeon Kim, Kwan Hoon Jo, Eun Yeong Mo, Eun Sook Kim, Hye Soo Kim, Je Ho Han, Sung-dae Moon
Korean J Intern Med. 2022;37(2):398-410. Published online December 15, 2021
Background/Aims: Germline mutations of the rearranged during transfection (RET) gene cause multiple endocrine neoplasia type 2 (MEN2). About 85% of RET mutations in MEN2 occur in codon Cys634. The RET D631Y mutation has recently been discovered, and we have studied its molecular expres..
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The 2020 revision of the guidelines for the management of myeloproliferative neoplasms
Sung-Yong Kim, Sung Hwa Bae, Soo-Mee Bang, Ki-Seong Eom, Junshik Hong, Seongsoo Jang, Chul Won Jung, Hee-Jin Kim, Ho Young Kim, Min Kyoung Kim, Soo-Jeong Kim, Yeung-Chul Mun, Seung-Hyun Nam, Jinny Park, Jong-Ho Won, Chul Won Choi
Korean J Intern Med. 2021;36(1):45-62. Published online December 4, 2020
In 2016, the World Health Organization revised the diagnostic criteria for myeloproliferative neoplasms (MPNs) based on the discovery of disease-driving genetic aberrations and extensive analysis of the clinical characteristics of patients with MPNs. Recent studies have suggested that additional som..
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Recent insights regarding the molecular basis of myeloproliferative neoplasms
Mi-Ae Jang, Chul Won Choi
Korean J Intern Med. 2020;35(1):1-11. Published online November 29, 2019
Myeloproliferative neoplasms (MPNs) are a heterogeneous group of clonal disorders characterized by the overproduction of mature blood cells that have an increased risk of thrombosis and progression to acute myeloid leukemia. Next-generation sequencing studies have provided key insights regarding the..
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Hemato-oncology
The impact of primary tumor location in patients with metastatic colorectal cancer: a Korean Cancer Study Group CO12-04 study
Jae Ho Byun, Joong Bae Ahn, Sun Young Kim, Jung Hun Kang, Dae Young Zang, Seok Yun Kang, Myoung Joo Kang, Byoung Yong Shim, Sun Kyung Baek, Bong-Seog Kim, Kyung Hee Lee, Soon Il Lee, Sang-Hee Cho, Byeong Seok Sohn, Samyong Kim, In Gyu Hwang, Eun Mi Nam, Bong-Gun Seo, Sang Cheul Oh, Myung-Ah Lee, Sang-Cheol Lee, Ji Hyung Hong, Young Suk Park
Korean J Intern Med. 2019;34(1):165-177. Published online November 28, 2017
Background/Aims: Colorectal cancer is associated with different anatomical, biological, and clinical characteristics. We determined the impact of the primary tumor location in patients with metastatic colorectal cancer (mCRC).
Methods: Demographic data and clinical information were collected from 1..
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Recent advances in the diagnosis and management of primary myelofibrosis
Katsuto Takenaka, Kazuya Shimoda, Koichi Akashi
Korean J Intern Med. 2018;33(4):679-690. Published online April 20, 2018
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm (MPN) in which dysregulation of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathways is the major pathogenic mechanism. Most patients with PMF carry a driver mutation in the JAK2, MPL (my..
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Etc
Primary pyomyositis in North India: a clinical, microbiological, and outcome study
Susheel Kumar, Ashish Bhalla, Rajveer Singh, Navneet Sharma, Aman Sharma, Vikas Gautam, Surjit Singh, Subhash Varma
Korean J Intern Med. 2018;33(2):417-431. Published online January 18, 2018
Background/Aims: Pyomyositis is an infective condition with primary involvement of the skeletal muscles. There is sparse recent literature on patients with pyomyositis.
Methods: This study was carried out at emergency services of a tertiary care center located in subtropical area of Indian subcont..
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Synchronous parathyroid carcinoma and papillary thyroid carcinoma in a patient with long-standing schizophrenia
Cho-Ok Baek, Ki Hoi Kim, Sun Kyung Song
Korean J Intern Med. 2017;32(6):1104-1107. Published online October 17, 2017
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Cardiology
Immediate multivessel revascularization may increase cardiac death and myocardial infarction in patients with ST-elevation myocardial infarction and multivessel coronary artery disease: data analysis from real world practice
Woo-Young Chung, Jae-Bin Seo, Dong-Hyun Choi, Young-Seok Cho, Joo Myung Lee, Jung-Won Suh, Tae-Jin Youn, In-Ho Chae, Dong-Ju Choi
Korean J Intern Med. 2016;31(3):488-500. Published online April 6, 2016
Background/Aims: The best revascularization strategy for patients with both acute ST-elevation myocardial infarction (STEMI) and multivessel coronary disease (MVD) is still debatable. We aimed to compare the outcomes of multivessel revascularization (MVR) with those of culprit-only revascularization..
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Gastroenterology
Clinical outcome of acute nonvariceal upper gastrointestinal bleeding after hours: the role of urgent endoscopy
Dong-Won Ahn, Young Soo Park, Sang Hyub Lee, Cheol Min Shin, Jin-Hyeok Hwang, Jin-Wook Kim, Sook-Hyang Jeong, Nayoung Kim, Dong Ho Lee
Korean J Intern Med. 2016;31(3):470-478. Published online April 6, 2016
Background/Aims: This study was performed to investigate the clinical role of urgent esophagogastroduodenoscopy (EGD) for acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) performed by experienced endoscopists after hours.
Methods: A retrospective analysis was performed for consecutively ..
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Synchronous second primary cancers in patients with squamous esophageal cancer: clinical features and survival outcome
Jin Seo Lee, Ji Yong Ahn, Kee Don Choi, Ho June Song, Yong Hee Kim, Gin Hyug Lee, Hwoon-Yong Jung, Jin-Sook Ryu, Sung-Bae Kim, Jong Hoon Kim, Seung-Il Park, Kyung-Ja Cho, Jin-Ho Kim
Korean J Intern Med. 2016;31(2):253-259. Published online February 11, 2016
Background/Aims: Unexpected diagnosis of synchronous second primary cancers (SPC) complicates physicians’ decision-making because clinical details of squamous esophageal cancer (EC) patients with SPC have been limited. We evaluated clinical features and treatment outcomes of patients with synchron..
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Hemato-oncology
Guidelines for the management of myeloproliferative neoplasms
Chul Won Choi, Soo-Mee Bang, Seongsoo Jang, Chul Won Jung, Hee-Jin Kim, Ho Young Kim, Soo-Jeong Kim, Yeo-Kyeoung Kim, Jinny Park, Jong-Ho Won
Korean J Intern Med. 2015;30(6):771-788. Published online October 30, 2015
Polycythemia vera, essential thrombocythemia, and primary myelofibrosis are collectively known as ‘Philadelphia-negative classical myeloproliferative neoplasms (MPNs).’ The discovery of new genetic aberrations such as Janus kinase 2 (JAK2) have enhanced our understanding of the pathophysio..
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Gastroenterology
Roadmap for elimination of gastric cancer in Korea
David Y. Graham
Korean J Intern Med. 2015;30(2):133-139. Published online February 27, 2015
Most gastric cancers are caused by infection with the common human bacterial pathogen, Helicobacter pylori. It is now accepted that gastric cancer can be prevented and virtually eliminated by H. pylori eradication and this knowledge was responsible for country-wide H. pylori era..
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Clinicopathological characteristics of synchronous and metachronous gastric neoplasms after endoscopic submucosal dissection
Mi Young Jang, Jin Woong Cho, Wang Guk Oh, Sung Jun Ko, Shang Hoon Han, Hoon Ki Baek, Young Jae Lee, Ji Woong Kim, Gum Mo Jung, Yong Keun Cho
Korean J Intern Med. 2013;28(6):687-693. Published online October 29, 2013
Background/AimsEndoscopic submucosal dissection (ESD) has become accepted as a minimally invasive treatment for gastric neoplasms. However, the development of synchronous or metachronous gastric lesions after endoscopic resection has become a major problem. We investigated the..
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Two Lung Masses with Different Responses to Pemetrexed
Kwang Young Park, Jae Wook Jung, Seung Bum Nam, Ho Jin Lee, Hyo Seok Kim, Yoon Hee Choi, Jae Cheol Lee
Korean J Intern Med. 2010;25(2):213-216. Published online June 1, 2010
We described here a patient who had two lung masses. Although the two masses had the same histology and a similar good response to initial chemotherapy with gemcitabine and carboplatin, the response to pemetrexed as a second-line treatment was different after re-growth of the tumors. These two lu..
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Longlasting Remission of Primary Hepatic Mucosa-associated Lymphoid Tissue (MALT) Lymphoma Achieved by Radiotherapy Alone
Sang Yun Shin, Jin Seok Kim, Jong Keun Lim, Jee Sook Hahn, Woo Ick Yang, Chang Ok Suh
Korean J Intern Med. 2006;21(2):127-131. Published online June 30, 2006
Primary hepatic lymphoma is a rare disorder representing less than 1% of all extranodal lymphomas. Histological examination of a primary hepatic lymphoma usually reveals a diffuse large B-cell lymphoma; there have been few reports of primary hepatic mucosa-associated lymphoid tissue (MALT) lympho..
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