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Gastroenterology / Review
Metabolic musculoskeletal disorders in patients with inflammatory bowel disease
Young Joo Yang, Seong Ran Jeon
Korean J Intern Med. 2025;40(2):181-195. Published online March 1, 2025
Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, is a chronic inflammatory disorder that affects not only the gastrointestinal tract but also extraintestinal organs, leading to various extraintestinal manifestations and complications. Among these, musculoske..
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Geriatrics / Original Article
A link between systemic low-grade inflammation and frailty in older adults: clinical evidence from a nationwide population-based study
Min-gu Kang, Hee-Won Jung, Beom-Jun Kim
Korean J Intern Med. 2024;39(6):1011-1020. Published online July 23, 2024
Background/Aims: Despite the possible role of systemic low-grade inflammation on frailty, the majority of previous studies have focused solely on the phenotypic frailty with limited participant numbers, thereby weakening the evidence supporting the notion that circulating C-reactive protein (CRP) co..
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Geriatrics / Original Article
Predictors of 3-month mortality with muscle ultrasound and palliative prognostic tools among patients admitted to palliative care units
Zeynep Irmak Kaya, Yelda Öztürk, Sinem Gürcü, Gülgün Uncu, Anıl Uçan, Mert Eşme, Berrin Yalınbaş Kaya, Cafer Balci
Korean J Intern Med. 2023;38(4):557-565. Published online March 31, 2023
Background/Aims: Prognostic factors are an important issue in progressive and life-limiting diseases. This study evaluate 3-month mortality in patients admitted to the palliative care unit (PCU).
Methods: In this study, the patient’s demographics, comorbidities, nutritional status, and laboratory..
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Nephrology / Review
Sarcopenia in chronic kidney disease: from bench to bedside
Da Woon Kim, Sang Heon Song
Korean J Intern Med. 2023;38(3):303-321. Published online April 20, 2023
Sarcopenia is a condition characterized by a loss of muscle mass and function. In chronic kidney disease (CKD), where a chronic catabolic state exists, sarcopenia commonly occurs through various mechanisms, resulting in muscle wasting and decreased muscle endurance. Sarcopenic patients with CKD have..
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Gastroenterology / Original Article
Prevalence and associated risk of advanced colorectal neoplasia in adults with sarcopenia
[letter]
Min Cheol Kim, Kyeong Ok Kim, Min Kyu Kang
Korean J Intern Med. 2022;37(2):294-303. Published online December 16, 2021
Background/Aims: Although several studies have shown that sarcopenia is associated with poor outcomes in colorectal cancer patients, the impact of sarcopenia on the development of colorectal neoplasia remains unclear. We aimed to evaluate the prevalence and association of colorectal neoplasia, espec..
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Geriatrics / Original Article
Sarcopenia is associated with severe erectile dysfunction in older adults: a population-based cohort study
Hyungchul Park, Il-Young Jang, Minkyu Han, Heayon Lee, Hee-Won Jung, Eunju Lee, Dae Hyun Kim
Korean J Intern Med. 2020;35(5):1245-1253. Published online April 21, 2020
Background/Aims: Sarcopenia and erectile dysfunction (ED) are associat ed with poor health and quality of life in older men. We investigate the association between sarcopenia and severe ED in community-dwelling older men.
Methods: We prospectively assessed sarcopenia and ED in 519, community-dwelli..
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Hemato-oncology / Original Article
The impact of sarcopenia on health-related quality of life in elderly people: Korean National
Health and Nutrition Examination Survey
Der Sheng Sun, Hyunyong Lee, Hyeon Woo Yim, Hye Sung Won, Yoon Ho Ko
Korean J Intern Med. 2019;34(4):877-884. Published online November 27, 2017
Background/Aims: The purpose of the study is to investigate the associations between sarcopenia and health-related quality of life in elderly men and women in Korea.
Methods: In a cross-sectional study using data from 2008 to 2011 Korean National Health and Nutrition Examination Survey, 4,937 adult..
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Nephrology / Original Article
Impact of sarcopenia on long-term mortality and cardiovascular events in patients undergoing hemodialysis
Jwa-Kyung Kim, Sung Gyun Kim, Ji-Eun Oh, Young-Ki Lee, Jung-Woo Noh, Hyung Jik Kim, Young Rim Song
Korean J Intern Med. 2019;34(3):599-607. Published online November 23, 2017
Background/Aims: A high body mass index (BMI) is known to correlate with better survival in patients on hemodialysis (HD). However, the impacts of body composition and sarcopenia on survival have not been well studied in this population.
Methods: One hundred and forty-two prevalent HD patients were..
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Endocrinology-metabolism / Review
Sarcopenia and sarcopenic obesity
Kyung Mook Choi
Korean J Intern Med. 2016;31(6):1054-1060. Published online November 1, 2016
Sarcopenia is an age-associated loss of muscle mass and decline in muscle strength; it is common in older adults and is associated with significant morbidity and mortality. Despite its prevalence, there is currently no universally adopted definition of sarcopenia. In addition to low muscle mass meas..
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Endocrinology-metabolism / Review
Differences among skeletal muscle mass indices derived from height-, weight-, and body mass index-adjusted models in assessing sarcopenia
Kyoung Min Kim, Hak Chul Jang, Soo Lim
Korean J Intern Med. 2016;31(4):643-650. Published online June 22, 2016
Aging processes are inevitably accompanied by structural and functional changes in vital organs. Skeletal muscle, which accounts for 40% of total body weight, deteriorates quantitatively and qualitatively with aging. Skeletal muscle is known to play diverse crucial physical and metabolic roles in hu..
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Rheumatology / Original Article
An analysis of age-related loss of skeletal muscle mass and its significance on osteoarthritis in a Korean population
Hun-Tae Kim, Hyun-Je Kim, Hee-Yun Ahn, Young-Hoon Hong
Korean J Intern Med. 2016;31(3):585-593. Published online March 15, 2016
Background/Aims: This study was conducted in order to analyze the effects of sarcopenia on age-related osteoarthritis (OA) of the knee in a Korean population.
Methods: All the Korean subjects who visited the Yeungnam University Medical Center Health Promotion Center between 2008 and 2012 in order t..
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