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Pulmonology
Development and validation of novel simple prognostic model for predicting mortality in Korean intensive care units using national insurance claims data
Ah Young Leem, Soyul Han, Kyung Soo Chung, Su Hwan Lee, Moo Suk Park, Bora Lee, Young Sam Kim
Korean J Intern Med. 2024;39(4):625-639. Published online April 19, 2024
Background/Aims: Intensive care unit (ICU) quality is largely determined by the mortality rate. Therefore, we aimed to develop and validate a novel prognostic model for predicting mortality in Korean ICUs, using national insurance claims data.
Methods: Data were obtained from the health insurance c..
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Infectious diseases
The effects of remdesivir on mortality and the requirement for mechanical ventilation in patients with COVID-19: a systematic review stratified by disease severity
Seungeun Ryoo, Miyoung Choi, Su-Yeon Yu, Young Kyung Yoon, Kyungmin Huh, Eun-Jeong Joo
Korean J Intern Med. 2024;39(1):160-171. Published online December 28, 2023
Background/Aims: The effectiveness of remdesivir treatment in reducing mortality and the requirement for mechanical ventilation (MV) remains uncertain, as randomized controlled trials (RCTs) have produced conflicting results.
Methods: We searched MEDLINE, EMBASE, Cochrane Central Register of Contro..
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Current concerns on journal article with preprint: Korean Journal of Internal Medicine perspectives
Hyoung-Chul Oh, Hyun Kang
Korean J Intern Med. 2023;38(3):332-337. Published online April 13, 2023
Preprints are preliminary research reports that have not yet been peer-reviewed. They have been widely adopted to promote the timely dissemination of research across many scientific fields. In August 1991, Paul Ginsparg launched an electronic bulletin board intended to serve a few hundred colleagues..
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Geriatrics
Factors associated with anticholinergic burden among older patients in long-term care hospitals in Korea
Jung-Yeon Choi, Hongsoo Kim, Young-il Jung, Seungyeon Chun, Sooyoung Yoo, Jae-Young Lim, Jin Young Ko, Kayoung Park, Kwang-il Kim
Korean J Intern Med. 2022;37(2):468-477. Published online February 18, 2022
Background/Aims: Drugs with anticholinergic properties (DAPs) are associated with adverse health outcomes in older patients. The objective of this study was to evaluate the factors that determine the prescribing of more DAPs in long-term care hospitals (LTCHs) in Korea. In addition, the current patt..
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Rheumatology
Efficacy and safety of hydroxychloroquine in osteoarthritis: a systematic review and meta-analysis of randomized controlled trials
Ambrish Singh, Anirudh Kotlo, Zhiqiang Wang, Thusharika Dissanayaka, Siddharth Das, Benny Antony
Korean J Intern Med. 2022;37(1):210-221. Published online April 22, 2021
Background/Aims: Conventional disease-modifying anti-rheumatic drugs have been trialed in osteoarthritis (OA). Hydroxychloroquine (HCQ), which has shown its effectiveness in rheumatoid arthritis, has been trialed for the treatment of OA; however, its efficacy and safety remain unclear. This systemat..
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Recent progress in the management of chronic cough
Woo-Jung Song, Jin An, Lorcan McGarvey
Korean J Intern Med. 2020;35(4):811-822. Published online May 20, 2020
Chronic cough is a common clinical condition with significant impact on quality of life and for which effective therapy remains an unmet clinical need. Over the past decade, there has been a major shift in how we approach this problem, driven by better appreciation of the clinical manifestation of ch..
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Cardiology
Chronic venous insufficiency and varicose veins of the lower extremities
Young Jin Youn, Juyong Lee
Korean J Intern Med. 2019;34(2):269-283. Published online October 26, 2018
Chronic venous insufficiency (CVI) of the lower extremities manifests itself in various clinical spectrums, ranging from asymptomatic but cosmetic problems to severe symptoms, such as venous ulcer. CVI is a relatively common medical problem but is often overlooked by healthcare providers because of ..
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Olmesartan is not associated with the risk of enteropathy: a Korean nationwide observational
cohort study
Seng Chan You, Hojun Park, Dukyong Yoon, Sooyoung Park, Boyoung Joung, Rae Woong Park
Korean J Intern Med. 2019;34(1):90-98. Published online November 27, 2017
Background/Aims: Olmesartan, a widely used angiotensin II receptor blocker (ARB), has been linked to sprue-like enteropathy. No cases of olmesartan-associated enteropathy have been reported in Northeast Asia. We investigated the associations between olmesartan and other ARBs and the incidence of ent..
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Infectious diseases
Drug utilization review of mupirocin ointment in a Korean university-affiliated hospital
Sung Hee Youn, Seung Soon Lee, Sukyeon Kim, Jeong-a Lee, Bum Joon Kim, Jounghee Kim, Hye-kyung Han, Jae-Seok Kim
Korean J Intern Med. 2015;30(4):515-520. Published online June 29, 2015
Background/Aims: Intranasa l mupirocin and chlorhexidine bathing are candidate strategies to prevent healthcare-associated infections caused by methicillin-resistant Staphylococcus aureus (MRSA). In Korea, intranasal mupirocin is not available, and mupirocin ointment, an over-the-counter drug..
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Cardiology
Microvascular angina: angina that predominantly affects women
Jin Joo Park, Sung-Ji Park, Dong-Ju Choi
Korean J Intern Med. 2015;30(2):140-147. Published online February 27, 2015
In women receiving evaluation for suspected ischemic symptoms, a “normal” diagnosis is five times more common than it is in men. These women are often labeled as having cardiac syndrome X, also known as microvascular angina (MVA). MVA is defined as angina pectoris caused by abnormalities of the s..
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Efficacy and Safety of Monthly 150 mg Oral Ibandronate in Women with Postmenopausal Osteoporosis: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Young Ho Lee, Gwan Gyu Song
Korean J Intern Med. 2011;26(3):340-347. Published online September 13, 2011
Background/AimsThe aim of this study was to assess the efficacy and safety of monthly oral 150 mg ibandronate in women with postmenopausal osteoporosis (PMO). MethodsA systematic review and meta-analysis were performed to determine treatment eff..
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Evaluation of Ceftriaxone Utilization at Multicenter Study
Hyuck Lee, Dongsik Jung, Joon Sup Yeom, Jun Seong Son, Sook-In Jung, Yeon-Sook Kim, Chun Kwan Kim, Hyun-Ha Chang, Shin-Woo Kim, Hyun Kyun Ki, Chi Sook Moon, Doo Ryeon Chung, Kyong Ran Peck, Jae-Hoon Song, Gun-Jo Woo
Korean J Intern Med. 2009;24(4):374-380. Published online November 27, 2009
Background/AimsAs bacterial resistance to antimicrobial agents has grown due to the increasing use of antimicrobial agents, we sought to evaluate the suitability of ceftriaxone usage (representative of third generation cephalosporins) at 10 university hospitals in Korea.
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