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Hemato-oncology
Efficacy of the granisetron transdermal system for the control of nausea and vomiting induced by highly emetogenic chemotherapy: a multicenter, randomized, controlled trial
Der Sheng Sun, Yoon Ho Ko, Jong Youl Jin, In Sook Woo, Suk Young Park, Yun Ae Eom, Jin Hyoung Kang, Hoon Kyo Kim
Korean J Intern Med. 2023;38(3):406-416. Published online March 11, 2022
Background/Aims: We compared the efficacy of the granisetron transdermal system (GTS) with that of ondansetron for controlling chemotherapy-induced nausea and vomiting (CINV) in patients treated with highly emetogenic chemotherapy (HEC).
Methods: We randomized a total of 389 patients to groups trea..
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Geriatric functional assessment for decision-making on adjuvant chemotherapy in older colon cancer patients
Hyun Jin Bang, Hyun Jeong Shim, Ga Ram Kim, Jun Eul Hwang, Woo Kyun Bae, Ik Joo Chung, Sang Hee Cho
Korean J Intern Med. 2022;37(3):660-672. Published online April 15, 2022
Background/Aims: Despite the increasing need for geriatric assessment prior to chemotherapy, the method for this assessment remains inadequate for older cancer patients. We aimed to propose a simple assessment method to predict the performance of adjuvant chemotherapy in older patients after colon c..
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Pediatric-inspired regimen with late intensification and increased dose of L-asparaginase for adult acute lymphoblastic leukemia: the KALLA 1406/1407 study
Dong Won Baek, Dae Young Kim, Sang Kyun Sohn, Youngil Koh, Sung-Hoon Jung, Ho-Young Yhim, Yunsuk Choi, Joon Ho Moon
Korean J Intern Med. 2021;36(6):1471-1485. Published online September 24, 2021
Background/Aims: The objective of this study was to evaluate the efficacy and feasibility of the pediatric-inspired regimen of the adult acute lymphoblastic leukemia (ALL) Working Party, the Korean Society of Hematology.
Methods: Data of 99 patients with newly diagnosed ALL, who were treated with t..
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Strong association between herpes simplex virus-1 and chemotherapy-induced oral mucositis in patients with hematologic malignancies
Junshik Hong, Hee-Kyung Park, Suhyun Park, Ahreum Lee, Yeon-Hee Lee, Dong-Yeop Shin, Youngil Koh, Ji-Yeob Choi, Sung-Soo Yoon, Youngnim Choi, Inho Kim
Korean J Intern Med. 2020;35(5):1188-1198. Published online September 9, 2019
Background/Aims: A link between oral cavity infections and chemotherapy-induced oral mucositis (CIOM) in patients with hematological malignancies (HMs) undergoing intensive chemotherapy (IC) or hematopoietic stem cell transplantation (HSCT) has been suggested. However, conclusive data are lacking, a..
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Squamous cell carcinoma of head and neck: what internists should know
Kyungsuk Jung, Manpreet Narwal, Seon Young Min, Bhumsuk Keam, Hyunseok Kang
Korean J Intern Med. 2020;35(5):1031-1044. Published online July 14, 2020
Squamous cell carcinoma of head and neck (SCCHN) is a group of cancer arising from mucosal surfaces of the head and neck. Optimal management of SCCHN requires a multidisciplinary team of surgical oncologists, radiation oncologists, medical oncologists, nutritionist, and speech-language pathologists,..
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Systemic treatment for advanced urothelial cancer: an update on recent clinical trials and current treatment options
Inkeun Park, Jae Lyun Lee
Korean J Intern Med. 2020;35(4):834-853. Published online July 1, 2020
After cisplatin-based chemotherapy became the standard treatment for metastatic urothelial cancer (mUC), very little progress has been made in the treatment landscape of this condition until recently. With increased knowledge about the molecular biology of mUC and advances in the field of cancer imm..
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Hemato-oncology
Surrogate decision making of chemotherapy consent: do we really provide informed consent of chemotherapy for patients?
Jung Hye Kwon, Sun Kyung Baek, Bong-Seog Kim, Su-Jin Koh, Hee Kyung Ahn, Joo Han Lim, Chiyeon Lim, Do Yeun Kim
Korean J Intern Med. 2019;34(3):626-633. Published online May 31, 2018
Background/Aims: Despite increased demand for cancer patient’s to make their own decisions based on an adequate understanding of what is involved in chemotherapy, the primary signing agent and the reasons for surrogate signing have not been appropriately evaluated.
Methods: The ethics committee of..
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Clinical characteristics and treatment propensity in elderly patients aged over 80 years with colorectal cancer
Yun Hwa Jung, Jae Young Kim, Yu Na Jang, Sang Hoon Yoo, Gyo Hui Kim, Kang Min Lee, In Kyu Lee, Su Mi Chung, In Sook Woo
Korean J Intern Med. 2018;33(6):1182-1193. Published online November 24, 2017
Background/Aims: Elderly patients (≥ 80 years) with colorectal cancer (CRC) tend to avoid active treatment at the time of diagnosis despite of recent advances in treatment. The aim of this study was to determine treatment propensity of elderly patients aged ≥ 80 years with CRC in clinical practice ..
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The neutrophil-to-lymphocyte ratio prechemotherapy and postchemotherapy as a prognostic marker in metastatic gastric cancer
Hyunho Kim, Sang Mi Ro, Ji Hyun Yang, Joon Won Jeong, Ji Eun Lee, Sang Young Roh, In-Ho Kim
Korean J Intern Med. 2018;33(5):990-999. Published online May 4, 2018
Background/Aims: Markers of inflammation have been associated with outcomes in various cancers. The purpose of this study was to evaluate whether systemic inf lammatory markers and their f luctuations can predict survival and chemotherapy response in patients with metastatic gastric cancer (mGC).
M..
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Retrospective analysis of palliative chemotherapy for the patients with bladder adenocarcinoma: Korean Cancer Study Group Genitourinary and Gynecology Cancer Committee
Moon Jin Kim, Young Sam Kim, Sung Yong Oh, Suee Lee, Young-Jin Choi, Young Mi Seol, Min Jae Park, Ki Hyang Kim, Lee Chun Park, Jung Hun Kang, In-Gyu Hwang, Soon Il Lee, Seung Taek Lim, Hyo Song Kim, Ho Yeong Lim, Sun Young Rha, Hyo-Jin Kim
Korean J Intern Med. 2018;33(2):383-390. Published online April 6, 2016
Background/Aims: Because of rarity, role of chemotherapy of bladder adenocarcinoma are still unidentified. Therefore, we performed a retrospective analysis of the clinical features and chemotherapy outcomes of bladder adenocarcinoma.
Methods: Eligible patients for this retrospective analysis were i..
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Cardiology
Pathophysiology and preventive strategies of anthracycline-induced cardiotoxicity
Woo-Baek Chung, Ho-Joong Youn
Korean J Intern Med. 2016;31(4):625-633. Published online July 1, 2016
Cardiotoxicity is a well-known complication following treatment with anthracyclines. However, they are still widely used in chemotherapy for breast cancer, lymphoma, leukemia, and sarcoma, among others. Patient clinical characteristics, such as age, sex, comorbidities, anthracycline dose and infusio..
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Duodenal adenocarcinoma following a
neuroendocrine tumor in the duodenum
Bun Kim, Ji Hye Huh, Youngsook Kim, Moon Jae Chung, Jeong Youp Park, Si Young Song, Seung Woo Park
Korean J Intern Med. 2014;29(1):96-100. Published online January 2, 2014
Primary duodenal adenocarcinoma is a rare malignant neoplasm accounting for
0.3% of all gastrointestinal tract carcinomas. We herein present one case of duodenal
adenocarcinoma after duodenal neuroendocrine carcinoma. Poorly differentiated
duodenal neuroendocrine carcinoma with liver metastasis (..
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Gastroenterology
Current status of chemotherapy for the treatment of advanced biliary tract cancer
Takashi Sasaki, Hiroyuki Isayama, Yousuke Nakai, Kazuhiko Koike
Korean J Intern Med. 2013;28(5):515-524. Published online August 14, 2013
Chemotherapy is indispensable for the treatment of advanced biliary tract cancer. Recently, reports regarding first-line chemotherapy have increased, and first-line chemotherapy treatment has become gradually more sophisticated. Gemcitabine and cisplatin combination therapy (or gemcitabine and ox..
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Hemato-oncology
Molecular targeted therapy for advanced gastric cancer
Jong Gwang Kim
Korean J Intern Med. 2013;28(2):149-155. Published online February 27, 2013
Although medical treatment has been shown to improve quality of life and prolong survival, no significant progress has been made in the treatment of advanced gastric cancer (AGC) within the last two decades. Thus, the optimum standard first-line chemotherapy regimen for AGC remains debatable, and..
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Feasibility of Non-TBI Conditioning with Busulfan and Fludarabine for Allogeneic Stem Cell Transplantation in Lymphoid Malignancy
Ho Cheol Shin, Yoo Jin Lee, Joon Ho Joon Ho, Soo Jung Lee, Byung Woog Kang, Yee Soo Chae, Jong Gwang Kim, Jun Young Choi, Jong Won Seo, Yu Kyung Kim, Jang Soo Suh, Sang Kyun Sohn
Korean J Intern Med. 2012;27(1):72-83. Published online February 28, 2012
Background/AimsThis retrospective study evaluated the transplantation outcomes of patients with adult lymphoid malignancies who received chemotherapy-based conditioning with busulfan and fludarabine (BuFlu) and busulfan and cyclophosphamide (BuCy2). Method.. </div>
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<a class="artiletitle" href="/journal/view.php?number=162384" onmouseover="showAbstract('162384' );" onmouseout="hideAbstract('162384' );"><b><font>Severe Pulmonary Adverse Effects in Lymphoma Patients Treated with Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) Regimen Plus Rituximab</font></b></a>
<div style="padding-top:2px;padding-left:0px" class="article_authors">Kyu-Hyoung Lim, Ho-Il Yoon, Young Ae Kang, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang, Jae Ho Lee, Choon-Taek Lee, Jong Seok Lee</div>
<div style="padding-top:2px;padding-left:0px" class="article_issue">
<em>Korean J Intern Med.</em> 2010;25(1):86-92. Published online February 26, 2010 </div>
<div class="doi">DOI: <a href="https://doi.org/10.3904/kjim.2010.25.1.86"><font class="doi">https://doi.org/10.3904/kjim.2010.25.1.86</font></a>
<a href="/journal/CitedByRenew.php?number=162384" onclick="window.open(this.href, 'CrossRef Citedby', 'width=800,height=800,scrollbars=yes');return false;" style="color:#DD434F;font-size:10pt;"> Crossref 22</a>
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<sec><title>Background/AimsThe aim of our study was to determine the incidence and clinical features of severe pulmonary complications in patients receiving cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or rituximab plus CHOP (R-CHOP) as the initial treatment for lymph..
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Clinical Characteristics of Pulmonary Embolism with Underlying Malignancy
Ji Eun Lee, Hye-Ryoun Kim, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young-Soo Shim, Seok-Chul Yang
Korean J Intern Med. 2010;25(1):66-70. Published online February 26, 2010
Background/AimsThe risk of venous thromboembolism (VTE), which encompasses deep vein thrombosis and pulmonary embolism (PE), increases in patients with cancer. Anticancer treatment is also associated with an increased risk for VTE. We conducted this study to investigate the cl..
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