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Nephrology
Kidney replacement therapy trends in end-stage kidney disease patients in South Korea during the COVID-19 pandemic
Ah-Young Kim, Min-Jeong Lee, Heejung Choi, Hankil Lee, Inwhee Park
Korean J Intern Med. 2024;39(6):967-978. Published online October 24, 2024
Background/Aims: The corona virus disease 2019 posed a major risk for end-stage kidney disease (ESKD) cases. Our study aimed to assess changes in kidney replacement therapy (KRT) trends and healthcare access for these patients during the pandemic.
Methods: We retrospectively analyzed nationwide dat..
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A retrospective study on the efficacy of Roxadustat in peritoneal dialysis patients with erythropoietin hyporesponsiveness
Jie Liu, Shuang Li, Fan Yang, Tianyu Li, Rui Li, Yousuf Waheed, Chen Meng, Shulin Li, Kun Liu, Yanshan Tong, Haisheng Xu, Chuankuo Tian, Xinglei Zhou
Korean J Intern Med. 2024;39(3):488-500. Published online April 23, 2024
Background/Aims: Roxadustat, an oral medication for treating renal anemia, is a hypoxia-inducible factor prolyl hydroxylase inhibitor used for regulating iron metabolism and promoting erythropoiesis. To investigate the efficacy and safety of roxadustat in patients undergoing peritoneal dialysis (PD)..
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The role of roxadustat in chronic kidney disease patients complicated with anemia
Jie Liu, Fan Yang, Yousuf Waheed, Shulin Li, Kun Liu, Xinglei Zhou
Korean J Intern Med. 2023;38(2):147-156. Published online January 2, 2023
The incidence of chronic kidney disease (CKD) is increasing worldwide and the current prevalence rate is 13.4%. There are > 120 million CKD patients in China and this number is expected to increase. One of the main abnormalities in patients with CKD and kidney impairment is decreased synthesis of er..
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Executive summary of the Korean Society of Nephrology 2021 clinical practice guideline for optimal hemodialysis treatment
Ji Yong Jung, Kyung Don Yoo, Eunjeong Kang, Hee Gyung Kang, Su Hyun Kim, Hyoungnae Kim, Hyo Jin Kim, Tae-Jin Park, Sang Heon Suh, Jong Cheol Jeong, Ji-Young Choi, Young-Hwan Hwang, Miyoung Choi, Yae Lim Kim, Kook-Hwan Oh; the Clinical Practice Guideline Work Group
Korean J Intern Med. 2022;37(4):701-718. Published online June 3, 2022
The Korean Society of Nephrology (KSN) has published a clinical practice guideline (CPG) document for maintenance hemodialysis (HD). The document, 2021 Clinical Practice Guideline on Optimal HD Treatment, is based on an extensive evidence-oriented review of the benefits of preparation, initiation, a..
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Hemato-oncology
Cancer incidence according to the National Health Information Database in Korean patients with end-stage renal disease receiving hemodialysis
Jisun Myung, Jung Hye Choi, Joo Hark Yi, Inah Kim
Korean J Intern Med. 2020;35(5):1210-1219. Published online February 20, 2020
Background/Aims: The aim of this study was to investigate incidence, survival, and risk factors of cancer in end-stage renal disease (ESRD) patients with hemodialysis using information from the National Health Information Database (NHID).
Methods: Using the NHID, we identified ESRD patients who sta..
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Gastroenterology
Full-dose sofosbuvir plus low-dose ribavirin for hepatitis C virus genotype 2-infected patients on hemodialysis
Hee Yeon Seo, Myeong-Sook Seo, Sun-Young Yoon, Jong Wook Choi, Soon Young Ko
Korean J Intern Med. 2020;35(3):559-565. Published online May 10, 2019
Background/Aims: New direct-acting antivirals have shown surprising success in the treatment of hepatitis C, not only in the general population, but also in difficult-to-treat cohorts. However, there is still limited data regarding direct-acting antivirals, including sofosbuvir (SOF), in the context..
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Nephrology
Low parathyroid hormone level predicts infection-related mortality in incident dialysis patients: a prospective cohort study
Yu Ah Hong, Jeong Ho Kim, Yong Kyun Kim, Yoon Kyung Chang, Cheol Whee Park, Suk Young Kim, Yon Su Kim, Shin-Wook Kang, Nam-Ho Kim, Yong-Lim Kim, Chul Woo Yang
Korean J Intern Med. 2020;35(1):160-170. Published online October 28, 2019
Background/Aims: Parathyroid hormone (PTH) is an important factor influencing immunologic dysfunction, but the effect of PTH level on infection-related outcomes remains unclear in incident dialysis.
Methods: We evaluated a multicenter prospective cohort study of 1,771 incident dialysis patients (1,..
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Effects of aspirin resistance and mean platelet volume on vascular access failure in hemodialysis patients
AJin Cho, Myung Jin Choi, Young-Ki Lee, Han Chae Hoon, Ja-Ryong Koo, Jong-Woo Yoon, Jung-Woo Noh
Korean J Intern Med. 2019;34(6):1304-1312. Published online July 23, 2018
Background/Aims: Maintaining the patency of vascular access (VA) in hemodialysis (HD) patients is important and can be life-saving. We investigated the effects of aspirin resistance and mean platelet volume (MPV) on VA failure in HD patients.
Methods: We enrolled 163 patients on maintenance HD. VA ..
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Seropositive rate of the anti-hepatitis A immunoglobulin G antibody in maintenance hemodialysis subjects from two hospitals in Korea
Hyunsuk Kim, Jiwon Ryu, Young-Ki Lee, Myung Jin Choi, Ajin Cho, Ja-Ryong Koo, Sae Yun Baik, Eun Hee Lee, Jong-Woo Yoon, Jung-Woo Noh
Korean J Intern Med. 2019;34(6):1297-1303. Published online February 23, 2018
Background/Aims: Hepatitis A virus (HAV) is a self-limiting infectious disease, but 1% of subjects develop fulminant hepatitis. The prevalence of the anti-HAV immunoglobulin G (IgG) antibody in hemodialysis subjects in Korea remains unknown. The purpose of this study was to describe and compare the ..
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Association between initial vascular access and survival in hemodialysis according to age
Ha Yeon Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
Korean J Intern Med. 2019;34(4):867-876. Published online November 20, 2017
Background/Aims: This study aims to demonstrate whether the association between initial vascular access and mortality among hemodialysis patients varies by age.
Methods: We conducted a retrospective study that included 2,552 patients who started hemodialysis. Vascular access was divided into three ..
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Intradialytic exercise improves physical function and reduces intradialytic hypotension and depression in hemodialysis patients
So Yon Rhee, Jin Kyung Song, Suk Chul Hong, Jae Won Choi, Hee Jung Jeon, Dong Ho Shin, Eun Hee Ji, Eun-Hee Choi, Jiyeon Lee, Aram Kim, Seung Wook Choi, Jieun Oh
Korean J Intern Med. 2019;34(3):588-598. Published online August 25, 2017
Background/Aims: As numbers of maintenance hemodialysis patients are growing, debilitating conditions of muscle wasting and atrophy are becoming some of the greatest concerns in end-stage renal disease patients. Exercise training has various potential benefits in terms of prevention of a sustained d..
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Current treatment status and medical costs for hemodialysis vascular access based on analysis of the Korean Health Insurance Database
Hyung Seok Lee, Young-Su Ju, Young Rim Song, Jwa Kyung Kim, Sun Ryoung Choi, Narae Joo, Hyung Jik Kim, Pyoungju Park, Sung Gyun Kim
Korean J Intern Med. 2018;33(6):1160-1168. Published online October 30, 2018
Background/Aims: The Republic of Korea is a country where the hemodialysis population is growing rapidly. It is believed that the numbers of treatments related to vascular access-related complications are also increasing. This study investigated the current status of treatment and medical expenses f..
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Predialysis hyponatremia and mortality in elderly patients beginning to undergo hemodialysis
Seon Ha Baek, Sejoong Kim, Ki Young Na, Suhnggwon Kim, Ho Jun Chin
Korean J Intern Med. 2018;33(5):970-979. Published online October 19, 2017
Background/Aims: Predialysis hyponatremia has been recently reported to be associated with mortality in incident hemodialysis patients. However, whether hyponatremia is associated with unfavorable outcomes in elderly patients remains unknown. We hypothesized that nephrology referral inf luences hypo..
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Clinical usefulness of bioimpedance analysis for assessing volume status in patients receiving maintenance dialysis
Jung Hwan Park, Young-Il Jo, Jong-Ho Lee
Korean J Intern Med. 2018;33(4):660-669. Published online June 28, 2018
Chronic volume overload is associated with left ventricular hypertrophy and high cardiovascular mortality in patients undergoing dialysis. Therefore, estimating body fluid status is important in these patients. However, most dry-weight assessments are still performed clinically, while attempts have ..
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Pre-existing arterial pathologic changes affecting arteriovenous fistula patency and cardiovascular mortality in hemodialysis patients
Ja Young Lee, Young Ok Kim
Korean J Intern Med. 2017;32(5):790-797. Published online August 22, 2017
The radiocephalic arteriovenous fistula (AVF) provides optimal vascular access for hemodialysis; it has a higher long-term patency rate and fewer complications than other vascular access methods. However, the AVF has a high primary failure rate. The presence of small-diameter vessels at anastomosis ..
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The pattern of choosing dialysis modality and related mortality outcomes in Korea: a national population-based study
Hyung Jong Kim, Jung Tak Park, Seung Hyeok Han, Tae-Hyun Yoo, Hyeong-Cheon Park, Shin-Wook Kang, Kyoung Hoon Kim, Dong-Ryeol Ryu, Hyunwook Kim
Korean J Intern Med. 2017;32(4):699-710. Published online June 26, 2017
Background/Aims: Since comorbidities are major determinants of modality choice, and also interact with dialysis modality on mortality outcomes, we examined the pattern of modality choice according to comorbidities and then evaluated how such choices affected mortality in incident dialysis patients.
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Ascites reinfusion dialysis of refractory ascites as a bridge to kidney and liver transplantation in a patient on hemodialysis
Kyung Yoon Chang, Hyung Wook Kim, Dong Chan Jin, Young Soo Kim
Korean J Intern Med. 2017;32(2):363-364. Published online January 19, 2016
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Nephrology
Which dialysis unit blood pressure is the most accurate for predicting home blood pressure in patients undergoing hemodialysis?
In-Cheol Yoon, Hye-Min Choi, Dong-Jin Oh
Korean J Intern Med. 2017;32(1):117-124. Published online April 7, 2016
Background/Aims: We investigated which dialysis unit blood pressure (BP) is the most useful for predicting home BP in patients undergoing hemodialysis (HD). Methods: Patients undergoing HD who had been treated > 3 months were included in this study. Exclusion criteria were hospitalized patients with..
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The impact of high serum bicarbonate levels on mortality in hemodialysis patients
Kyung Yoon Chang, Hyung Wook Kim, Woo Jeong Kim, Yong Kyun Kim, Su-Hyun Kim, Ho Chul Song, Young Ok Kim, Dong Chan Jin, Euy Jin Choi, Chul Woo Yang, Yong-Lim Kim, Nam-Ho Kim, Shin-Wook Kang, Yon-Su Kim, Young Soo Kim
Korean J Intern Med. 2017;32(1):109-116. Published online April 5, 2016
Background/Aims: The optimal serum bicarbonate level is controversial for patients who are undergoing hemodialysis (HD). In this study, we analyzed the impact of serum bicarbonate levels on mortality among HD patients. Methods: Prevalent HD patients were selected from the Clinical Research Center re..
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The impact of blood flow rate during hemodialysis on all-cause mortality
Kyung Yoon Chang, Su-Hyun Kim, Young Ok Kim, Dong Chan Jin, Ho Chul Song, Euy Jin Choi, Yong-Lim Kim, Yon-Su Kim, Shin-Wook Kang, Nam-Ho Kim, Chul Woo Yang, Yong Kyun Kim
Korean J Intern Med. 2016;31(6):1131-1139. Published online February 22, 2016
Background/Aims: Inadequacy of dialysis is associated with morbidity and mortality in chronic hemodialysis (HD) patients. Blood flow rate (BFR) during HD is one of the important determinants of increasing dialysis dose. However, the optimal BFR is unclear. In this study, we investigated the impact o..
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