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Review

August 26, 2026


Epidemiological and clinical trends of malignant small-bowel tumors in Asia
Jung Rock Moon, Seong Ran Jeon
Korean J Intern Med. 2026;41(5):799-807.

Malignant small-bowel tumors are uncommon, accounting for < 5% of all gastrointestinal cancers, yet their incidence has exhibited a steady rise in both Western and Asian populations. This increase is...

Review

September 1, 2026


Optimizing multiple diagnostic modalities for small bowel evaluation: a strategic approach
Dong Jun Oh, Yun Jeong Lim
Korean J Intern Med. 2026;41(5):785-798.

Over the past two decades, the small bowel, once considered a diagnostic “blind spot,” has become fully and comprehensively accessible. This review summarizes recent advances in the main diagnostic modalities:...

Review

September 1, 2026


Current insights into the diagnosis and management of small bowel bleeding
Sang Hyun Kim, Ja Seol Koo
Korean J Intern Med. 2026;41(5):808-818.

Small bowel bleeding accounts for 5–10% of gastrointestinal (GI) hemorrhage and remains a diagnostic challenge because of its diverse etiologies and subtle clinical presentation. Advances in small bowel imaging have...

Review

September 1, 2026


Heart failure with preserved ejection fraction in women: a sex-specific clinical review
Soo-Jin Kim, Mi-Seung Shin
Korean J Intern Med. 2026;41(5):819-830.

Heart failure with preserved ejection fraction (HFpEF) affects approximately half of the current heart failure population and demonstrates marked sex-related differences in pathophysiology, clinical presentation, and therapeutic response. These distinctions...

Review

September 1, 2026


Health effects of air pollution on chronic respiratory diseases
Yong Suk Jo, Jin Woo Song
Korean J Intern Med. 2026;41(5):831-846.

Exposure to both outdoor and indoor air pollution poses significant global public health challenges at all life stages. As the respiratory system serves as the primary entry route for inhaled...

Original Article

September 1, 2026


Population-specific rare variants influence age at diagnosis in Korean inflammatory bowel disease
Mina Cho, DongHwan Shin, Jongwook Yu, et al.
Korean J Intern Med. 2026;41(5):847-857.

1. WES identified 12 novel rare coding variants associated with age at diagnosis in Korean IBD, mostly specific to East Asian populations. 2. GSG1 carriers showed earlier disease onset and a...

Original Article

September 1, 2026


Clinical feasibility of deep learning-assisted classification of Helicobacter pylori infection in endoscopic imagery: a reader study
Jun-young Seo, Jiseon Kang, Do Hoon Kim, et al.
Korean J Intern Med. 2026;41(5):862-872.

1. A deep learning model classified H. pylori infection on endoscopic images with 97.0% patient-level accuracy and 100% sensitivity. 2. Deep learning assistance improved the mean diagnostic accuracy of 14 endoscopists...

Original Article

September 1, 2026


Prognostic implications of functional significance, high-risk plaque and vessel characteristics in patients with diabetes mellitus
Jin-Eun Song, Seokhun Yang, Masahiro Hoshino, et al.
Korean J Intern Med. 2026;41(5):873-883.

1. CCTA-derived HRP and HRV characteristics provided independent prognostic value for TVF beyond invasive FFR in patients with DM. 2. Even in diabetic patients with deferred vessels with FFR > 0.80,...

Original Article

September 1, 2026


Prognostic significance of artificial intelligence-quantified late gadolinium enhancement on cardiac magnetic resonance in hypertrophic cardiomyopathy
Young-Sang Jeong, Jong-Il Park, Kang-Un Choi, et al.
Korean J Intern Med. 2026;41(5):884-893.

1. Artificial intelligence (AI)-based quantification of late gadolinium enhancement (LGE) on cardiac magnetic resonance independently predicts adverse cardiovascular outcomes in patients with hypertrophic cardiomyopathy. 2. Automated and reproducible AI-based LGE analysis...

Original Article

September 1, 2026


Parathyroid hormone–related protein–mediated hypercalcemia of malignancy: insights from a multicenter clinical data warehouse
Jinyoung Kim, Yuri Shin, Jeonghoon Ha, et al.
Korean J Intern Med. 2026;41(5):907-915.

1. PTHrP-mediated hypercalcemia is an important endocrine cause of severe hypercalcemia in patients with malignancy. 2. PTHrP-related hypercalcemia is observed across a broad range of cancer types and is associated with...

Original Article

September 1, 2026


Diabetes progression and severe hypoglycemia: a nationwide cohort study of 2,475,605 adults with type 2 diabetes mellitus
Kyu-Na Lee, Bongseong Kim, Mee Kyoung Kim, et al.
Korean J Intern Med. 2026;41(5):916-926.

1. A diabetes progression score (ranging from 0 to 6)—based on diabetes duration, number of oral glucose-lowering drugs, insulin use, and the presence of chronic kidney disease, cardiovascular disease, and...

Original Article

September 1, 2026


Mortality risk associated with permanent central venous catheter use in the oldest-old population: a nationwide cohort study
Joo Un Park, Chang Min Park, Do Hyoung Kim, et al.
Korean J Intern Med. 2026;41(5):927-939.

1. In octogenarians and nonagenarians, permanent CVC use was associated with a two- to three-fold higher risk of mortality, compared with AV access. 2. Both AVF and AVG use were associated...

Original Article

September 1, 2026


Probable obesity hypoventilation syndrome in a Korean medical intensive care unit: clinical characteristics and outcomes
Kyu Jin Lee, Hong Yeul Lee, Jinwoo Lee, et al.
Korean J Intern Med. 2026;41(5):894-904.

1. The proportion of probable OHS was 3.0% (BMI ≥ 27 kg/m2) and 6.5% (BMI ≥ 30 kg/m2) among obese patients in the MICU of a tertiary hospital in Korea. 2....

Original Article

September 1, 2026


Clinical and immunologic features of adult primary antibody deficiency according to IVIGRT exposure
Jung-Eun Han, Hyun young Lee, Haeng Jun Kim, et al.
Korean J Intern Med. 2026;41(5):940-951.

1. IgG3SCD was the most prevalent PAD phenotype and was more frequently observed among Korean adults with PAD receiving IVIGRT in routine clinical practice. 2. The Ajou-PAD score showed modest discriminatory...

Original Article

September 1, 2026


Concomitant cryoglobulinaemic vasculitis alongside ANCA-associated vasculitis: concurrence or coincidental individual occurrence
Jeong Yeop Whang, Jang Woo Ha, Jihye Chung, et al.
Korean J Intern Med. 2026;41(5):952-960.

1. Cryoglobulin was detected in the sera of two of the 136 patients with AAV, both exhibiting repeated cryoglobulinaemia, and these patients were classified as having CryoVas alongside AAV, yielding...
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    Volume 41(5); Sep 2026

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