| Editorials |
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Navigating the risks of using concomitant antipeptic agents in light of osteoporotic concerns
Hae Won Yoo, Su Jin Hong
Korean J Intern Med. 2024;39(2):201-202. Published online February 28, 2024
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Metformin and tuberculosis: extraordinary stories of ordinary co-prevalent patients
Won-Il Choi
Korean J Intern Med. 2024;39(2):203-204. Published online February 28, 2024
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| Reviews |
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Nighttime administration of antihypertensive medication: a review of chronotherapy in hypertension
Hyun-Jin Kim, Sang-Ho Jo
Korean J Intern Med. 2024;39(2):205-214. Published online November 16, 2023
Hypertension remains a global health concern because of suboptimal blood pressure control despite advancements in antihypertensive treatments. Chronotherapy, defined as evening or bedtime administration of medication based on biological rhythms, is emerging as a potential strategy to improve blood p..
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New targets for type 2-low asthma
Quang Luu Quoc, Youngwoo Choi, Gyu-Young Hur, Hae-Sim Park
Korean J Intern Med. 2024;39(2):215-227. Published online February 6, 2024
Asthma is characterized by airway obstruction and inflammation, and presents significant diagnostic and treatment challenges. The concept of endotypes has improved understanding of the mechanisms of asthma and has stimulated the development of effective treatment strategies. Sputum profiles may be u..
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| Original Articles |
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Gastroenterology
The combined use of anti-peptic agents is associated with an increased risk of osteoporotic fracture: a nationwide case-control study
Dong Jun Oh, Ji Hyung Nam, Hyun Seok Lee, Yeo Rae Moon, Yun Jeong Lim
Korean J Intern Med. 2024;39(2):228-237. Published online February 7, 2024
Background/Aims: Long-term use of acid suppressants such as proton pump inhibitors (PPIs) and histamine 2 receptor antagonist (H2RA) has been associated with the risk of osteoporotic fracture. Acid suppressants and muco-protective agents (MPAs) are often used together as anti-ulcer agents. We evalua..
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Endoscopic mucosal resection using anchored snare Tip-in versus precut technique for small rectal neuroendocrine tumors
Seung Wook Hong, Dong-Hoon Yang, Yoo Jin Lee, Dong Hoon Baek, Jaeyoung Chun, Hyun Gun Kim, Sung Joo Kim, Seung-Mo Hong, Dae-Seong Myung
Korean J Intern Med. 2024;39(2):238-247. Published online December 8, 2023
Background/Aims: Small rectal neuroendocrine tumors (NETs) can be treated with modified endoscopic mucosal resection (EMR). However, an optimal EMR method remains to be established. We aimed to assess the non-inferiority of Tip-in EMR versus precut EMR (EMR-P) for treating rectal NETs.
Methods: Thi..
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Model for end-stage liver disease-3.0 vs. model for end-stage liver disease-sodium: mortality prediction in Korea
Jeong Han Kim, Yong Joon Cho, Won Hyeok Choe, So Young Kwon, Byung-Chul Yoo
Korean J Intern Med. 2024;39(2):248-260. Published online February 1, 2024
Background/Aims: The model for end-stage liver disease (MELD) serves as an indicator for short-term mortality among patients diagnosed with liver cirrhosis (LC) and is used to prioritize patients for liver transplantation. In 2021, the updated version of MELD, MELD-3.0, was introduced to improve the..
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Reduced risk of gastrointestinal bleeding associated with eupatilin in aspirin plus acid suppressant users: nationwide population-based study
Hyun Seok Lee, Ji Hyung Nam, Dong Jun Oh, Yeo Rae Moon, Yun Jeong Lim
Korean J Intern Med. 2024;39(2):261-271. Published online December 14, 2023
Background/Aims: Mucoprotective agents, such as eupatilin, are often prescribed to prevent gastrointestinal (GI) bleeding in addition to an acid suppressant despite the absence of a large-scale study. We evaluated the additional effect of eupatilin on the prevention of GI bleeding in both the upper ..
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Cardiology
Metabolic syndrome awareness in the general Korean population: results from a nationwide survey
Hyun-Jin Kim, Mi-Seung Shin, Kyung-Hee Kim, Mi-Hyang Jung, Dong-Hyuk Cho, Ju-Hee Lee, Kwang Kon Koh
Korean J Intern Med. 2024;39(2):272-282. Published online January 30, 2024
Background/Aims: Metabolic syndrome (MetS) raises the risk of cardiovascular disease and type 2 diabetes. An awareness of MetS is vital for early detection and proactive management, which can mitigate the risks associated with MetS. Therefore, our study aimed to investigate the level of awareness of..
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Association of epicardial adipose tissue with metabolic risk factors on cardiovascular outcomes: serial coronary computed tomography angiography study
Sungjoon Park, Dong Eun Kim, Su Min Kim, JungMin Choi, Sang Joon Park, Hae-Young Lee, Eun Ju Chun
Korean J Intern Med. 2024;39(2):283-294. Published online February 14, 2024
Background/Aims: Epicardial adipose tissue (EAT) shares pathophysiological properties with other visceral fats and potentially triggers local inflammation. However, the association of EAT with cardiovascular disease (CVD) is still debatable. The study aimed to observe the changes and associations in..
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Pulmonology
Mechanical ventilation in patients with idiopathic pulmonary fibrosis in Korea: a nationwide cohort study
Jae Kyeom Sim, Seok Joo Moon, Juwhan Choi, Jee Youn Oh, Young Seok Lee, Kyung Hoon Min, Gyu Young Hur, Sung Yong Lee, Jae Jeong Shim
Korean J Intern Med. 2024;39(2):295-305. Published online February 8, 2024
Background/Aims: The prognosis of patients with idiopathic pulmonary fibrosis (IPF) and respiratory failure requiring mechanical ventilation is poor. Therefore, mechanical ventilation is not recommended. Recently, outcomes of mechanical ventilation, including those for patients with IPF, have improv..
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Relationship between metformin use and mortality in tuberculosis patients with diabetes: a nationwide cohort study
Eunki Chung, Dawoon Jeong, Jeongha Mok, Doosoo Jeon, Hee-Yeon Kang, Heejin Kim, Heesun Kim, Hongjo Choi, Young Ae Kang
Korean J Intern Med. 2024;39(2):306-317. Published online February 6, 2024
Background/Aims: To determine whether metformin, which is considered a host-directed therapy for tuberculosis (TB), is effective in improving the prognosis of patients with TB and diabetes mellitus (DM), who have higher mortality than those without DM.
Methods: This cohort study included patients w..
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Clinical impact of pleural fluid carcinoembryonic antigen on therapeutic strategy and efficacy in lung adenocarcinoma patients with malignant pleural effusion
Jaehee Lee, Deok Heon Lee, Ji Eun Park, Yong Hoon Lee, Sun Ha Choi, Hyewon Seo, Seung Soo Yoo, Shin Yup Lee, Seung-Ick Cha, Jae Yong Park, Chang Ho Kim
Korean J Intern Med. 2024;39(2):318-326. Published online February 14, 2024
Background/Aims: Epidermal growth factor receptor (EGFR) mutation is important in determining the treatment strategy for advanced lung cancer patients with malignant pleural effusion (MPE). Contrary to serum carcinoembryonic antigen (S-CEA) levels, the associations between pleural fluid CEA (PF-CEA)..
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Hemato-oncology
Prognostic Significance Of Sequential 18f-fdg Pet/Ct During Frontline Treatment Of Peripheral T Cell Lymphomas
Ga-Young Song, Sung-Hoon Jung, Seo-Yeon Ahn, Mihee Kim, Jae-Sook Ahn, Je-Jung Lee, Hyeoung-Joon Kim, Jang Bae Moon, Su Woong Yoo, Seong Young Kwon, Jung-Joon Min, Hee-Seung Bom, Sae-Ryung Kang, Deok-Hwan Yang
Korean J Intern Med. 2024;39(2):327-337. Published online January 25, 2024
Background/Aims: The prognostic significance of 18F-fluorodeoxyglucose (FDG)-positron emission tomography-computed tomography (PET/CT) in peripheral T-cell lymphomas (PTCLs) are controversial. We explored the prognostic impact of sequential 18F-FDG PET/CT during frontline chemo..
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Rheumatology
Effect of belimumab in patients with systemic lupus erythematosus treated with low dose or no corticosteroids
Yeo-Jin Lee, Soo Min Ahn, Seokchan Hong, Ji-Seon Oh, Chang-Keun Lee, Bin Yoo, Yong-Gil Kim
Korean J Intern Med. 2024;39(2):338-346. Published online November 30, 2023
Background/Aims: Systemic lupus erythematosus (SLE) responder index (SRI)-4 response has been achieved with belimumab treatment in patients with moderate disease activity in cornerstone clinical trials and following studies. However, most studies involved patients treated with a mean prednisolone-eq..
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Predictors of renal relapse in Koreans with lupus nephritis after achieving complete response: a 35-years of experience at a single center
Howook Jeon, Jennifer Lee, Su-Jin Moon, Seung-Ki Kwok, Ji Hyeon Ju, Wan-Uk Kim, Sung-Hwan Park
Korean J Intern Med. 2024;39(2):347-359. Published online January 22, 2024
Background/Aims: Renal relapse has known to be a poor prognostic factor in patients with lupus nephritis (LN), but there were few studies that identified the risk factors of renal relapse in real world. We conducted this study based on 35-years of experience at a single center to find out predictors..
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| Correspondence |
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Duration of corticosteroid treatment in hospitalized COVID-19 patients, less is more
Marko Lucijanic, Ivan Papic, Maja Ortner Hadziabdic
Korean J Intern Med. 2024;39(2):360-361. Published online February 6, 2024
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| Images of interest |
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The significance of ophthalmologic examination in a patient with xanthoma
In Sun Goak, Seol A Jang, Yu Jin Jin, In-Cheon You, Ji Hyun Park
Korean J Intern Med. 2024;39(2):362-363. Published online December 22, 2023
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Migration of central vein stent into the right atrium
Kyoung-Woo Seo, Jin-Sun Park
Korean J Intern Med. 2024;39(2):364-365. Published online November 10, 2023
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Pregabalin-induced rhabdomyolysis in hemodialysis patient
Dong Eon Kim, Sang Heon Song
Korean J Intern Med. 2024;39(2):366-367. Published online November 30, 2023
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