Original Articles |
Original Article
Is Hypercapnea a Predictor of Better Survival in the Patients who Underwent Mechanical Ventilation for Chronic Obstructive Pulmonary Disease (COPD)?
Joo Hun Park, Younsuck Koh, Chae-Man Lim, Sang-Bum Hong, Yeon Mok Oh, Tae Sun Shim, Sang Do Lee, Woo Sung Kim, Dong Soon Kim, Won Dong Kim
Korean J Intern Med. 2006;21(1):1-9. Published online March 30, 2006
BackgroundThere are contradictory reports concerning hypercapnia as a predictor of a better outcome in COPD. This study examined the clinical implications of hypercapnea in COPD patients (M:F = 59:19) who required mechanical ventilation. Methods..
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Original Article
Severe Airway Hyperresponsiveness in School-aged Boys with a High Body Mass Index
An-Soo Jang, June Huk Lee, Sung Woo Park, Mee Yong Shin, Do Jin Kim, Choon-Sik Park
Korean J Intern Med. 2006;21(1):10-14. Published online March 30, 2006
BackgroundAn association between obesity and asthma has been reported. The prevalence of airway hyperresponsiveness (AHR), results of skin prick tests, body mass index (BMI), and asthma symptoms were examined in schoolchildren. MethodsThe result..
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Original Article
ThE Role of Endoscopic Surgery for Completely Obstructive Endobronchial Benign Tumor
Jae-Chol Choi, Chang Min Yu, Yon Ju Ryu, Kyeongman Jeon, Kyoung A Choi, O Jung Kwon, Hojoong Kim
Korean J Intern Med. 2006;21(1):15-19. Published online March 30, 2006
BackgroundThe improving techniques of therapeutic bronchoscopy have been replacing conventional surgery for resecting endobronchial benign tumor. However, there could be some limitation for performing bronchoscopic intervention for the patients with complete bronchial obstruct..
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Original Article
Hepatocyte Growth Factor/c-Met Signaling in Regulating Urokinase Plasminogen Activator in Human Stomach Cancer: A Potential Therapeutic Target for Human Stomach Cancer
Kyung Hee Lee, Eun Young Choi, Myung Soo Hyun, Byung Ik Jang, Tae Nyeun Kim, Sang Woon Kim, Sun Kyo Song, Jung Hye Kim, Jae-Ryong Kim
Korean J Intern Med. 2006;21(1):20-27. Published online March 30, 2006
BackgroundUp-regulation of the hepatocyte growth factor (HGF), its transmembrane tyrosine kinase receptor (c-Met), and urokinase type plasminogen activator (uPA), is associated with the development and metastasis of various types of cancers. However, the mechanisms by which HG..
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Original Article
p53 Genetic Polymorphism of Gastric cancer in Korea
Woo Chul Chung, Kang Moon Lee, Bo In Lee, Ji Sung Chun, So Yeon Lee, U-Im Chang, Soo Heon Park, Jin Mo Yang, Kyu Yong Choi, In-Sik Chung
Korean J Intern Med. 2006;21(1):28-32. Published online March 30, 2006
Background/AimsDeletion or functional loss of the p53 tumor suppression gene plays a role in oncogenic transformation. The codon 72 polymorphism on exon 4 in the p53 gene produces variant proteins with either arginine (Arg) or proline (Pro), a..
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Original Article
Association of serum albumin and homocysteine levels and cardio-ankle vascular index in patients with continuous ambulatory peritoneal dialysis
Jung-Ahn Lee, Do-Hyung Kim, Soo-Jeong Yu, Dong-Jin Oh, Suk-Hee Yu
Korean J Intern Med. 2006;21(1):33-38. Published online March 30, 2006
BackgroundThe cardio-ankle vascular index (CAVI) is a newly developed arteriosclerotic measurement that has been proposed as an alternative to aortic pulse-wave velocity (PWV). The present study used the CAVI to identify the main factors associated with arteriosclerosis in con..
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Case Reports |
Case Report
Acute Respiratory Failure Associated with Cryptococcal Pneumonia and Disseminated Cryptococcosis in an AIDS Patient
Kyoung-Hwan Lee, U-Im Chang, Hyung-Wook Kim, Guilsun Kim, Sung Kyoung Kim, Jinyoung Yoo, Seong-Heon Wie
Korean J Intern Med. 2006;21(1):39-42. Published online March 30, 2006
A 36-year-old homosexual Mexican man was admitted to our hospital, with a 30-day history of fever and headache. Upon cerebrospinal fluid examination, the patient's white blood cell count was 1,580/L, total protein was 26 mg/dL, sugar was 17 mg/dL, and his intracranial pressure was 23 cmH2
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Case Report
Unpredicted Severe Toxicity after 5-Fluorouracil Treatment due to Dihydropyrimidine Dehydrogenase Deficiency
Jin Ho Baek, Jong Gwang Kim, Shi Nae Kim, Dong Hwan Kim, Sang Kyun Sohn, Young Jun Hong, Kyu Bo Lee
Korean J Intern Med. 2006;21(1):43-45. Published online March 30, 2006
Dihydropyrimidine dehydrogenase (DPD) is the initial and rate-limiting enzyme in the catabolism of 5-fluorouracil (5-FU). Thus, patients with a DPD deficiency are at risk of developing severe 5-FU-associated toxicity. A 37-year-old female with gastric cancer underwent a curative operation, ..
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Case Report
Epstein-Barr virus-associated Hodgkin's disease following renal transplantation
Jung-Hye Choi, Myung-Ju Ahn, Young-Ha Oh, Sang-Woong Han, Ho-Jung Kim, Young-Yeul Lee, In-Soon Kim
Korean J Intern Med. 2006;21(1):46-49. Published online March 30, 2006
Post-transplant lymphoproliferative disorders (PTLD) have been recognized as a complication of immunosuppression and occur with a reported incidence of 1 to 8% of recipients receiving solid organ transplantation. PTLD are classified into two major categories, polymorphic and monomorphic PTLD. The..
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Case Report
A Case of Behçet's Disease with Pericarditis, Thrombotic Thrombocytopenic Purpura, Deep Vein Thrombosis and Coronary Artery Pseudo Aneurysm
Chang Mo Kwon, Seung Hyun Lee, Jin Ho Kim, Kyu Hyung Lee, Hyun Do Kim, Yeong Hoon Hong, Choong Ki Lee
Korean J Intern Med. 2006;21(1):50-56. Published online March 30, 2006
Behçet's disease with concomitant thrombotic thrombocytopenic purpura (TTP), coronary artery stenosis and coronary artery pseudo aneurysm is rare. Here we report a case of Behçet's disease with several cardiovascular complications, namely: pericarditis, deep vein thrombosis (DVT), TTP, coronary..
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Case Report
Peripheral T-cell Lymphoma-Unspecified (PTCL-U) Presenting with Hypereosinophilic Syndrome and Pleural Effusions
Won Choi, Yeon Hee Park, Kwang Hyun Paik, Yoon Hwan Chang, Seung-Sook Lee, Baek-Yeol Ryoo, Sung Hyun Yang
Korean J Intern Med. 2006;21(1):57-61. Published online March 30, 2006
Hypereosinophilic syndrome (HES) is a clinical disorder characterized by persistent eosinophilia and systemic involvement, in which a specific causative factor for the eosinophilia cannot be verified during a certain period of time. There have been only a few reported cases of this syndrome assoc..
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Case Report
A Case of Gastric Tuberculosis Mimicking Advanced Gastric Cancer
Seong-Eun Kim, Ki-Nam Shim, Su Jin Yoon, Sung-Ae Jung, Tae Hun Kim, Kwon Yoo, Il Hwan Moon
Korean J Intern Med. 2006;21(1):62-67. Published online March 30, 2006
Tuberculosis of the stomach is quite rare, both as a primary or secondary infection. It can present as a facet of a multiorgan disease process or may result from immunodeficiency. Here, we report a rare, interesting case of gastric tuberculosis which morphologically mimicked advanced gastric canc..
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Case Report
Delayed Puberty due to Pituitary Stalk Dysgenesis and Ectopic Neurohypophysis
Hye Jin Yoo, Kyung Mook Choi, Ohk Hyun Ryu, Sang Il Suh, Nan Hee Kim, Sei Hyun Baik, Dong Seop Choi
Korean J Intern Med. 2006;21(1):68-72. Published online March 30, 2006
Hypopituitarism is not a common cause of delayed puberty. A 22 year old man was referred to our clinic because of the absence of the development of secondary sexual characteristics. The patient had no complaints of physical discomfort. Random serum testosterone and luteinizing hormone level were ..
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Case Report
A Patient with Primary Squamous Cell Carcinoma of the Thyroid Intermingled with Follicular Thyroid Carcinoma that Remains Alive more than 8 Years after Diagnosis
Tae Sik Jung, Young Lyun Oh, Young-Ki Min, Myung-Shik Lee, Moon-Kyu Lee, Kwang-Won Kim, Jae Hoon Chung
Korean J Intern Med. 2006;21(1):73-78. Published online March 30, 2006
Primary squamous cell carcinoma of the thyroid is an extremely rare tumor with a highly aggressive clinical course. We report here on a patient with primary squamous cell carcinoma of the thyroid who remains alive more than 8 years after diagnosis. A 56-year-old man presented with a hoarse voice ..
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Case Report
Hemobilia from Ruptured Hepatic Artery Aneurysm in Polyarteritis Nodosa
Sung Soon Park, Byeong Uk Kim, Hye Suk Han, Ja Chung Goo, Joung Ho Han, Il Hun Bae, Seon Mee Park
Korean J Intern Med. 2006;21(1):79-82. Published online March 30, 2006
Hemobilia, in patients with the diagnosis of polyarteritis nodosa, is rare at clinical presentation and has a grave prognosis. We describe a case of massive hemobilia, due to aneurysmal rupture, in a patient with polyarteritis nodosa. A 39-year-old man was admitted to the hospital with upper abdo..
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Case Report
A Case of Pulmonary Cryptococcosis by Capsule-deficient Cryptococcus neoformans
Won Seok Cheon, Kwang-Seok Eom, Byoung Kwan Yoo, Seung Hun Jang, Joon-Woo Bahn, Dong-Gyu Kim, Ki-Suck Jung
Korean J Intern Med. 2006;21(1):83-87. Published online March 30, 2006
Pulmonary infection by capsule-deficient Cryptococcus neoformans (CDCN) is a very rare form of pneumonia and it is seldom seen in the immunocompetent host. The authors experienced a case of pulmonary cryptococcosis by CDCN in 25-year-old woman who was without any significant unde..
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