|
Review
Current status of pulmonary arterial hypertension in Korea
Albert Youngwoo Jang, Wook-Jin Chung
Korean J Intern Med. 2019;34(4):696-707. Published online July 1, 2019
Pulmonary arterial hypertension (PAH) is characterized by remodeling of the distal pulmonary arteries resulting in high pulmonary vascular resistance and, eventually, right ventricular heart failure. Although current advances in PAH therapy have improved outcomes, poor survival remains a reality wor..
|
|
|
Review
Current status and therapeutic considerations of hypertension in the elderly
Ju-Hee Lee, Kwang-Il Kim, Myeong-Chan Cho
Korean J Intern Med. 2019;34(4):687-695. Published online July 1, 2019
As the prevalence of hypertension in the elderly population is increasing, information regarding the characteristics, optimal blood pressure targets, and special considerations for elderly hypertensive patients is needed to improve clinical outcomes. Various factors should be considered when managin..
|
|
|
Corrigendum
Comparison of clinical utility between diaphragm excursion and thickening change using ultrasonography to predict extubation success
Jung-Wan Yoo, Seung Jun Lee, Jong Deog Lee, Ho Cheol Kim
Korean J Intern Med. 2019;34(3):686-686. Published online April 30, 2019
|
|
|
Corrigendum
Effect of vitamin D deficiency in Korean patients with acute respiratory distress syndrome
Sojung Park, Min Gee Lee, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh, Jin Won Huh
Korean J Intern Med. 2019;34(3):685-685. Published online April 30, 2019
|
|
|
Image of interest
Fever of unknown origin caused by intrathyroidal thymic carcinoma
Seung Min Chung, Kyung-Ju Kim, Jun Sung Moon, Young Hoon Hong, Su Hwan Kang
Korean J Intern Med. 2019;34(3):683-684. Published online August 13, 2018
|
|
|
Image of interest
Rapid changes in capillary morphology and architecture in a patient with dermatomyositis
Sung-Jo Park, In-Ho Choi, Hyun-Sook Kim
Korean J Intern Med. 2019;34(3):680-682. Published online January 5, 2018
|
|
|
Image of interest
Giant intra-abdominal cystic lymphangioma
Fatih Altintoprak, Mustafa Yener Uzunoglu, Kayhan Ozdemir, Enis Dikicier, Zeynep Kahyaoglu
Korean J Intern Med. 2019;34(3):678-679. Published online January 7, 2019
|
|
|
Rheumatology / Original Article
Risk of malignancy in patients with rheumatoid arthritis after anti-tumor necrosis factor therapy: results from Korean National Health Insurance claims data
Seung Min Jung, Seung-Ki Kwok, Ji Hyeon Ju, Yong-Beom Park, Sung-Hwan Park
Korean J Intern Med. 2019;34(3):669-677. Published online November 29, 2017
Background/Aims: Inhibition of tumor necrosis factor (TNF) is an effective treatment for rheumatoid arthritis (RA), but safety concerns about malignancy remain. The aim of this study was to evaluate cancer risk in RA patients treated with TNF inhibitors (TNFi), based on Korean Nationwide Health Insu..
|
|
|
Rheumatology / Original Article
Korean rheumatology workforce from 1992 to 2015: current status and future demand
Chan Uk Lee, Ji Na Kim, Ji-Won Kim, Sung-Hoon Park, Hwajeong Lee, Seong-Kyu Kim, Jung-Yoon Choe
Korean J Intern Med. 2019;34(3):660-668. Published online December 15, 2017
Background/Aims: Rheumatology in Korea has rapidly advanced in the 24 years since the subspecialty board certification program was established in 1992. The objective of this investigation was to analyze the distribution of rheumatology practices in Korea in order to better understand the rheumatolog..
|
|
|
Rheumatology / Original Article
Magnetic resonance imaging-assessed synovial and bone changes in hand and wrist joints of rheumatoid arthritis patients
Kyung-Ann Lee, Sang-Ho Min, Tae-Hyung Kim, Sang-Heon Lee, Hae-Rim Kim
Korean J Intern Med. 2019;34(3):651-659. Published online November 24, 2017
Background/Aims: Magnetic resonance imaging (MRI) is a sensitive and useful method for the detection of synovitis and joint destruction in rheumatoid arthritis (RA) patients. However, the patterns of MRI-detected bone erosion, bone marrow edema (BME), synovitis, and tenosynovitis have received insuf..
|
|
|
Allergy / Original Article
Prevalence of anaphylaxis and prescription rates of epinephrine auto-injectors in urban and rural areas of Korea
Hyunseok Cho, Jae-Woo Kwon
Korean J Intern Med. 2019;34(3):643-650. Published online October 26, 2018
Background/Aims: Despite the clinical importance anaphylaxis and the recent increase in its occurrence, studies regarding the epidemiology of anaphylaxis, risk factors for anaphylaxis, and epinephrine auto-injector (EAI) prescription status for patients with anaphylaxis remain poorly described. Thus..
|
|
|
Infectious diseases / Original Article
MicroRNA-16 inhibits cell proliferation and migration by targeting heat shock protein 70 in heat-denatured dermal fibroblasts
[retracted-article]
Chun Zhang, Jinhua Dai, Youfen Fan, Xianghui He, Renxiong Wei
Korean J Intern Med. 2019;34(3):634-642. Published online January 5, 2018
Background/Aims: This study aimed to investigate the precise mechanism and function of miR-16 in heat-denatured primary human dermal fibroblasts.
Methods: Primary human dermal fibroblasts were separated from normal human skin samples. Under heat stress, the levels of miR-16 and heat shock protein 7..
|
|
|
Hemato-oncology / Original Article
Surrogate decision making of chemotherapy consent: do we really provide informed consent of chemotherapy for patients?
Jung Hye Kwon, Sun Kyung Baek, Bong-Seog Kim, Su-Jin Koh, Hee Kyung Ahn, Joo Han Lim, Chiyeon Lim, Do Yeun Kim
Korean J Intern Med. 2019;34(3):626-633. Published online May 31, 2018
Background/Aims: Despite increased demand for cancer patient’s to make their own decisions based on an adequate understanding of what is involved in chemotherapy, the primary signing agent and the reasons for surrogate signing have not been appropriately evaluated.
Methods: The ethics committee of..
|
|
|
Hemato-oncology / Original Article
β-Catenin expression is associated with cell invasiveness in pancreatic cancer
Jin Niang Nan, Ok Ran Kim, Myung Ah Lee
Korean J Intern Med. 2019;34(3):618-625. Published online October 26, 2018
Background/Aims: This study was tried to determine the role of β-catenin in invasion in pancreatic cancer.
Methods: We analyzed cancer invasiveness according to β-catenin expression in pancreatic cancer cell line. We also investigated the change in cancer invasiveness when β-catenin expression was ch..
|
|
|
Hemato-oncology / Original Article
Comparison of the morphologic criteria (RECIST) and metabolic criteria (EORTC and PERCIST) in tumor response assessments: a pooled analysis
Hong Deok Kim, Bum Jun Kim, Hyeong Su Kim, Jung Han Kim
Korean J Intern Med. 2019;34(3):608-617. Published online January 17, 2018
Background/Aims: The Positron Emission Tomography Response Criteria in Solid Tumors (PERCIST) or European Organization for Research and Treatment of Cancer (EORTC) criteria are used to assess metabolic tumor responses. However, tumor responses have shown considerable discrepancies between the morpho..
|
|
|
Nephrology / Original Article
Impact of sarcopenia on long-term mortality and cardiovascular events in patients undergoing hemodialysis
Jwa-Kyung Kim, Sung Gyun Kim, Ji-Eun Oh, Young-Ki Lee, Jung-Woo Noh, Hyung Jik Kim, Young Rim Song
Korean J Intern Med. 2019;34(3):599-607. Published online November 23, 2017
Background/Aims: A high body mass index (BMI) is known to correlate with better survival in patients on hemodialysis (HD). However, the impacts of body composition and sarcopenia on survival have not been well studied in this population.
Methods: One hundred and forty-two prevalent HD patients were..
|
|
|
Nephrology / Original Article
Intradialytic exercise improves physical function and reduces intradialytic hypotension and depression in hemodialysis patients
So Yon Rhee, Jin Kyung Song, Suk Chul Hong, Jae Won Choi, Hee Jung Jeon, Dong Ho Shin, Eun Hee Ji, Eun-Hee Choi, Jiyeon Lee, Aram Kim, Seung Wook Choi, Jieun Oh
Korean J Intern Med. 2019;34(3):588-598. Published online August 25, 2017
Background/Aims: As numbers of maintenance hemodialysis patients are growing, debilitating conditions of muscle wasting and atrophy are becoming some of the greatest concerns in end-stage renal disease patients. Exercise training has various potential benefits in terms of prevention of a sustained d..
|
|
|
Endocrinology-metabolism / Original Article
Aromatase inhibitor use is a risk factor of carotid plaque presence in endocrine-responsive breast cancer patients
Da Hea Seo, Yongin Cho, Sujin Lee, Seho Park, Seung-Il Kim, Byeong Woo Park, Yumie Rhee
Korean J Intern Med. 2019;34(3):579-587. Published online August 25, 2017
Background/Aims: The aromatase inhibitors (AIs) are well known anti-hormonal therapy in endocrine-responsive breast cancer patients. It can lead to dyslipidemia and be the risk factor of cardiovascular disease due to low estrogen level. However, some recent studies comparing AIs with placebo have sh..
|
|
|
Pulmonology / Original Article
Left ventricular dysfunction in relation with systemic inflammation in chronic obstructive pulmonary disease patients
Sule Tas Gulen, Ufuk Eryilmaz, Mustafa Yilmaz, Fisun Karadag
Korean J Intern Med. 2019;34(3):569-578. Published online October 29, 2018
Background/Aims: Most important cause of mortality in chronic obstructive pulmonary disease (COPD) patients is known to be cardiovascular disease (CVD). The objective of the present study was to evaluate the echocardiographic parameters in COPD patients with or without pre-diagnosed CVD and to inves..
|
|
|
Pulmonology / Original Article
Efficacy and predictors of response to inhaled corticosteroid treatment for chronic cough
Ji Young Hong, Joo-Hee Kim, Sunghoon Park, Yong Il Hwang, Ki-Suck Jung, Seung Hun Jang
Korean J Intern Med. 2019;34(3):559-568. Published online December 13, 2018
Background/Aims: Inhaled corticosteroids (ICS) are a treatment of choice for eosinophilic airway diseases, but their efficacy for other causes of chronic cough is controversial.
Methods: We conducted a prospective observational study to determine the ICS efficacy and clinical predictors of response t..
|
|
|
