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Case Report
A Case of a Composite Adrenal Medullary Tumor of Pheochromocytoma and Ganglioneuroma Masquerading as Acute Pancreatitis
Eun-Kyoung Choi, Wan-Ho Kim, Keun-Yong Park
Korean J Intern Med. 2006;21(2):141-145. Published online June 30, 2006
Composite adrenal medullary tumors, composed of both pheochromocytoma and ganglioneuroma, are extremely rare, as are pheochromocytomas masquerading as acute relapsing pancreatitis. We recently experienced a case of a 48-year-old male with both these phenomena. The patient complained of an acute o..
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Case Report
Longlasting Remission of Primary Hepatic Mucosa-associated Lymphoid Tissue (MALT) Lymphoma Achieved by Radiotherapy Alone
Sang Yun Shin, Jin Seok Kim, Jong Keun Lim, Jee Sook Hahn, Woo Ick Yang, Chang Ok Suh
Korean J Intern Med. 2006;21(2):127-131. Published online June 30, 2006
Primary hepatic lymphoma is a rare disorder representing less than 1% of all extranodal lymphomas. Histological examination of a primary hepatic lymphoma usually reveals a diffuse large B-cell lymphoma; there have been few reports of primary hepatic mucosa-associated lymphoid tissue (MALT) lympho..
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Case Report
Thrombotic Thrombocytopenic Purpura after Percutaneous Coronary Intervention
Jung-Min Lee, Seung-Ho Hur, Chang-Wook Nam, Seung-Wook Han, Kee-Sik Kim, Yoon-Nyun Kim, Kwon-Bae Kim
Korean J Intern Med. 2006;21(2):120-122. Published online June 30, 2006
Thrombotic thrombocytopenic purpura (TTP) is a rapidly progressive hematological syndrome defined by the pentad of thrombocytopenia, microangiopathic hemolytic anemia, neurologic abnormalities, fever and renal dysfunction. TTP has been associated with major surgical procedures and specific medica..
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Original Article
The Incidence of Gastro-Esophageal Disease for the Patients with Typical Chest Pain and a Normal Coronary Angiogram
Chang-Wook Nam, Kee-Sik Kim, Young-Soo Lee, Sang-Hoon Lee, Seong-Wook Han, Seung-Ho Hur, Yoon-Nyun Kim, Kwon-Bae Kim, Byoung-Kuk Jang
Korean J Intern Med. 2006;21(2):94-96. Published online June 30, 2006
BackgroundAlthough patients may present with typical chest pain and exhibit ischemic changes on the cardiac stress test, they are frequently found to have a normal coronary angiogram. Thus, we wanted to determine which procedures should be performed in order to make an adequat..
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Original Article
Effect of Fenofibrate in Combination with Urate Lowering Agents in Patients with Gout
You-Hyun Lee, Chan-Hee Lee, Jisoo Lee
Korean J Intern Med. 2006;21(2):89-93. Published online June 30, 2006
BackgroundTo assess the efficacy of fenofibrate treatment in combination with urate lowering agents in patients with gout. MethodsFourteen male patients with chronic tophaceous or recurrent acute attacks of gout were evaluated in an open-label p..
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Case Report
Peripheral T-cell Lymphoma-Unspecified (PTCL-U) Presenting with Hypereosinophilic Syndrome and Pleural Effusions
Won Choi, Yeon Hee Park, Kwang Hyun Paik, Yoon Hwan Chang, Seung-Sook Lee, Baek-Yeol Ryoo, Sung Hyun Yang
Korean J Intern Med. 2006;21(1):57-61. Published online March 30, 2006
Hypereosinophilic syndrome (HES) is a clinical disorder characterized by persistent eosinophilia and systemic involvement, in which a specific causative factor for the eosinophilia cannot be verified during a certain period of time. There have been only a few reported cases of this syndrome assoc..
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Case Report
A Case of Behçet's Disease with Pericarditis, Thrombotic Thrombocytopenic Purpura, Deep Vein Thrombosis and Coronary Artery Pseudo Aneurysm
Chang Mo Kwon, Seung Hyun Lee, Jin Ho Kim, Kyu Hyung Lee, Hyun Do Kim, Yeong Hoon Hong, Choong Ki Lee
Korean J Intern Med. 2006;21(1):50-56. Published online March 30, 2006
Behçet's disease with concomitant thrombotic thrombocytopenic purpura (TTP), coronary artery stenosis and coronary artery pseudo aneurysm is rare. Here we report a case of Behçet's disease with several cardiovascular complications, namely: pericarditis, deep vein thrombosis (DVT), TTP, coronary..
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Case Report
Epstein-Barr virus-associated Hodgkin's disease following renal transplantation
Jung-Hye Choi, Myung-Ju Ahn, Young-Ha Oh, Sang-Woong Han, Ho-Jung Kim, Young-Yeul Lee, In-Soon Kim
Korean J Intern Med. 2006;21(1):46-49. Published online March 30, 2006
Post-transplant lymphoproliferative disorders (PTLD) have been recognized as a complication of immunosuppression and occur with a reported incidence of 1 to 8% of recipients receiving solid organ transplantation. PTLD are classified into two major categories, polymorphic and monomorphic PTLD. The..
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Case Report
Unpredicted Severe Toxicity after 5-Fluorouracil Treatment due to Dihydropyrimidine Dehydrogenase Deficiency
Jin Ho Baek, Jong Gwang Kim, Shi Nae Kim, Dong Hwan Kim, Sang Kyun Sohn, Young Jun Hong, Kyu Bo Lee
Korean J Intern Med. 2006;21(1):43-45. Published online March 30, 2006
Dihydropyrimidine dehydrogenase (DPD) is the initial and rate-limiting enzyme in the catabolism of 5-fluorouracil (5-FU). Thus, patients with a DPD deficiency are at risk of developing severe 5-FU-associated toxicity. A 37-year-old female with gastric cancer underwent a curative operation, ..
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Original Article
Is Hypercapnea a Predictor of Better Survival in the Patients who Underwent Mechanical Ventilation for Chronic Obstructive Pulmonary Disease (COPD)?
Joo Hun Park, Younsuck Koh, Chae-Man Lim, Sang-Bum Hong, Yeon Mok Oh, Tae Sun Shim, Sang Do Lee, Woo Sung Kim, Dong Soon Kim, Won Dong Kim
Korean J Intern Med. 2006;21(1):1-9. Published online March 30, 2006
BackgroundThere are contradictory reports concerning hypercapnia as a predictor of a better outcome in COPD. This study examined the clinical implications of hypercapnea in COPD patients (M:F = 59:19) who required mechanical ventilation. Methods..
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Case Report
Management of a Pregnant Patient with Graves' Disease Complicated by Propylthiouracil induced Agranulocytosis
Yoon-Young Cho, Ho Sang Shon, Hyun Dae Yoon
Korean J Intern Med. 2005;20(4):335-338. Published online December 31, 2005
Relapse and exacerbation of Graves' disease during pregnancy is rare, and thionamide induced agranulocytosis is an uncommon side effect. We report a case of a pregnant woman in her 24th week of gestation that experienced a relapse of Graves' disease that was complicated by propylthiour..
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Case Report
Non-Hodgkin's Lymphoma Manifest as Gingival Hyperplasia in a Renal Transplant Recipient
Jung Hyun Kwon, Joon Chang Song, Sang Hun Lee, So Young Lee, Chul Woo Yang, Yong Soo Kim, Byung Kee Bang
Korean J Intern Med. 2005;20(4):330-334. Published online December 31, 2005
Gingival hyperplasia is a frequent complication in transplant patients who receive cyclosporine or calcium channel blockers. We studied an unusual case involving a renal transplant recipient with post-transplant non-Hodgkin's lymphoma that manifested as gingival hyperplasia. We initially consider..
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Case Report
A Case of Septic Shock and Disseminated Intravascular Coagulation Complicated by Acute Myocardial Infarction Following Amniocentesis
Kye Hun Kim, Myung Ho Jeong, Ik Joo Chung, Jeong Gwan Cho, Tae Bok Song, Jong Chun Park, Jung Chaee Kang
Korean J Intern Med. 2005;20(4):325-329. Published online December 31, 2005
Maternal septic shock and disseminated intravascular coagulation (DIC) following amniocentesis is a relatively rare condition, and its incidence is only 0.03~0.19%. Acute myocardial infarction (AMI) associated with DIC is also rare. We report here on a 40-year-old female patient who had septic sh..
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Original Article
Hypoxic Regulation of VEGF, HIF-1(alpha) in Coronary Collaterals Development
Ki Chul Sung, Kyung Soo Kim, Sang Lee
Korean J Intern Med. 2005;20(4):295-302. Published online December 31, 2005
BackgroundThe interindividual variability for the development of collaterals in coronary artery disease is dependent on the hypoxic induction level of VEGF. To determine whether the hypoxic induction of VEGF is controlled by the transcription of HIF-1 (alpha), the VEGF and HIF..
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Original Article
Neutrophil Elastase Causes MUC5AC Mucin Synthesis Via EGF Receptor, ERK and NF-kB Pathways in A549 Cells
Jeong-Sup Song, Kyung-Sook Cho, Hyung-Kyu Yoon, Hwa-Sik Moon, Sung-Hak Park
Korean J Intern Med. 2005;20(4):275-283. Published online December 31, 2005
BackgroundNeutrophil elastase (NE) was found to increase the respiratory mucin gene, MUC5AC, although the molecular mechanisms of this process remain unknown. We attempted to determine the signal transduction pathway through which NE induces MUC5AC gene expression in bronchial..
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Case Report
Adult Onset Still's Disease as a Cause of Acute Severe Mitral and Aortic Regurgitation
Jae Seung Lee, Il No Do, Deok Hyun Kang, Seok Jung Joo, Bin Yoo, Hee Bom Moon, Chang-Keun Lee
Korean J Intern Med. 2005;20(3):264-267. Published online September 30, 2005
Adult onset Still's disease (AOSD) is an uncommon acute systemic inflammatory disease of unknown origin. The clinical features include high spiking fever, arthralgia or arthritis, transient maculopapular rash, lymphadenopathy, hepatosplenomegaly, and serositis. Pericarditis is the most common car..
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Case Report
Congenital Double-Orifice Mitral Valve with Mitral Regurgitation due to Flail Leaflet in an Elderly Patient
Shin-Jae Kim, Eun-Seok Shin, Sang-Gon Lee
Korean J Intern Med. 2005;20(3):251-254. Published online September 30, 2005
We report here on a case of double-orifice mitral valve with mitral regurgitation in a 75-year-old female who had complaints of mild dyspnea. Transthoracic and transesophageal echocardiography showed two orifices that were supplied by their own chordae from a different papillary muscle. Color Dop..
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Case Report
A Case of Uterine Cervical Cancer Presenting with Granulocytosis
Heui June Ahn, Yeon Hee Park, Yoon Hwan Chang, Sun Hoo Park, Min-Suk Kim, Baek Yeol Ryoo, Sung Hyun Yang
Korean J Intern Med. 2005;20(3):247-250. Published online September 30, 2005
Granulocytosis occurs in 40% of patients with lung and gastrointestinal cancers, 20% of patients with breast cancer, 30% of patients with brain tumor and ovarian cancer and 10% of patients with renal cell carcinoma. Granulocytosis occurs because of production of G-CSF, GM-CSF and IL-6. Uterine c..
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Original Article
Double Autologous Stem Cell Transplantation for Multiple Myeloma: A Korean Single Center Study
Ock Bae Ko, Shin Kim, Hyeok Shim, Jung-Hun Lee, Jung-Min Ahn, Soon-Man Yoon, Min-Hyok Jeon, Il-No Do, So-young Lee, Yong Gil Kim, Sang We Kim, Sung-Bae Kim, Sang-Hee Kim, Jung Shin Lee, Wookun Kim, Chan-Jung Park, Hyun-sook Chi, Cheolwon Suh
Korean J Intern Med. 2005;20(3):237-242. Published online September 30, 2005
BackgroundAlthough high dose chemotherapy coupled with an autologous stem cell transplantation (ASCT) is widely accepted as effective therapy for multiple myeloma (MM), few reports are available in Korea, especially in the area of double ASCT. We present the results of an inst..
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Original Article
Lack of Association of Glutathione S-transferase P1 Ile105Val Polymorphism with Aspirin-Intolerant Asthma
Jung-Mi Oh, Seung-Hyun Kim, Chang-Hee Suh, Dong-Ho Nahm, Hae-Sim Park, Young-Mok Lee, June-Hyuk Lee, Choon-Sik Park, Hyung-Doo Shin
Korean J Intern Med. 2005;20(3):232-236. Published online September 30, 2005
BackgroundGlutathion S-transferase P1 (GSTP1), the abundant isoform of glutathione S-transferase in lung epithelium, plays an important role in cellular protection against oxidative stress and toxic foreign chemicals. GSTP1 (Ile105Val) polymorphism has been reported to be asso..
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