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Original Article
Changing Donor Source Pattern for Kidney Transplantation over 40 Years: A Single-Center Experience
Byung Ha Chung, Mi Hyang Jung, Sung Ha Bae, Suk Hui Kang, Hyeon Seok Hwang, Bok Jin Hyoung, So Young Lee, Youn Ju Jeon, Bum Soon Choi, Cheol Whee Park, Yong-Soo Kim, Ji-Il Kim, In Sung Moon, Chul Woo Yang
Korean J Intern Med. 2010;25(3):288-293. Published online August 31, 2010
Background/AimsKidney transplantations at our center rely mainly on living donors. The purpose of this study was to suggest future donor supply directions by reviewing changing trends in donor type. MethodsDuring the past 40 years, 1,690 kidney ..
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Original Article
Effect of Glutathione Administration on Serum Levels of Reactive Oxygen Metabolites in Patients with Paraquat Intoxication: A Pilot Study
Jung-Hoon Kim, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2010;25(3):282-287. Published online August 31, 2010
Background/AimsBased on preliminary in vitro data from a previous study, we proposed that 50 mg/kg glutathione (GSH) would be adequate for suppressing reactive oxygen species in patients with acute paraquat (PQ) intoxication. Methods
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Original Article
Usefulness of Peak Systolic Strain Measurement by Automated Function Imaging in the Prediction of Coronary Perfusion in Patients with Acute Myocardial Infarction
Jung Sun Cho, Kye Hun Kim, Woo Seok Lee, Hyun Ju Yoon, Nam Sik Yoon, Young Joon Hong, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong, Jeong Gwan Cho, Jong Chun Park, Jung Chaee Kang
Korean J Intern Med. 2010;25(3):260-268. Published online August 31, 2010
Background/AimsThe usefulness of global longitudinal peak systolic strain (GLPSS) measurement by automated function imaging (AFI) in the prediction of perfusion status of infarct-related artery (IRA) before percutaneous coronary intervention (PCI) was evaluated.
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Original Article
Left Ventricular Dyssynchrony in Patients Showing Diastolic Dysfunction without Overt Symptoms of Heart Failure
Jae Hoon Kim, Hee Sang Jang, Byung Seok Bae, Seung Min Shin, Ki Ju Kim, Jung Gil Park, Hyun Jae Kang, Bong Ryeol Lee, Byung Chun Jung
Korean J Intern Med. 2010;25(3):246-252. Published online August 31, 2010
Background/AimsFew studies have assessed left ventricular (LV) dyssynchrony in cases of diastolic dysfunction that do not include overt symptoms of heart failure. We hypothesized that systolic or diastolic dyssynchrony involves unique features with respect to the degree of dia..
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Original Article
Variable Association between Components of the Metabolic Syndrome and Electrocardiographic Abnormalities in Korean Adults
Hong-Kyu Kim, Chul-Hee Kim, Kwan-Ho Ko, Seong-Wook Park, Joong-Yeol Park, Ki-Up Lee
Korean J Intern Med. 2010;25(2):174-180. Published online June 1, 2010
Background/AimsResting electrocardiogram (ECG) abnormalities have been strongly associated with cardiovascular disease mortality. Little is known, however, about the association between individual components of metabolic syndrome and ECG abnormalities, especially in Asian popu..
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Original Article
Diet and Airway Obstruction: A Cross Sectional Study from the Second Korean National Health and Nutrition Examination Survey
Jin Hwa Lee, Yun Su Sim, Gee Young Suh, Jeong-Seon Ryu, Dong Ho Shin, Kyung Haeng Koh, Yeon Jae Kim, Wan Park, Hyoung Kyu Yoon, Man Jae Lee, Jung Hyun Chang,
Korean J Intern Med. 2010;25(2):132-139. Published online June 1, 2010
Background/AimsSeveral dietary factors, such as antioxidant vitamins, have potential roles in the development of obstructive lung diseases. However, the results of studies on the relationships between dietary factors and obstructive lung diseases are inconsistent. The aim of t..
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Review
Molecular Mechanism of Insulin Resistance in Obesity and Type 2 Diabetes
Kangduk Choi, Young-Bum Kim
Korean J Intern Med. 2010;25(2):119-129. Published online June 1, 2010
Insulin resistance is a major risk factor for developing type 2 diabetes caused by the inability of insulin-target tissues to respond properly to insulin, and contributes to the morbidity of obesity. Insulin action involves a series of signaling cascades initiated by insulin binding to its recept..
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Case Report
A Case Report of the Second de Novo Acute Myeloid Leukemia (AML) Following Allogeneic Stem Cell Transplantation in a Patient with the First AML
Byung-Sik Cho, Hee-Je Kim, Ki-Sung Eom, Jong-Wook Lee, Woo-Sung Min, Chun-Choo Kim
Korean J Intern Med. 2010;25(1):110-113. Published online February 26, 2010
Secondary leukemia occurring after hematopoietic stem cell transplantation (HSCT) for acute myeloid leukemia (AML) is rare. Secondary AML usually follows autologous and not allogeneic transplants. When a new leukemia develops in a patient successfully treated with an allogeneic HSCT, the possibil..
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Case Report
Myasthenia Gravis Presenting as Isolated Respiratory Failure: A Case Report
Won Hee Kim, Jung Hyun Kim, Eun Kyung Kim, Sang Pil Yun, Kyung Keun Kim, Won Chan Kim, Hye Cheol Jeong
Korean J Intern Med. 2010;25(1):101-104. Published online February 26, 2010
Myasthenia gravis (MG) is often complicated by respiratory failure, known as a myasthenic crisis. However, most of the patients who develop respiratory symptoms do so during the late course of disease and have other neurological signs and symptoms. However, in some patients respiratory failure is..
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Original Article
Ethyl Acetate Fraction from Cudrania Tricuspidata Inhibits IL-1β-Stimulated Osteoclast Differentiation through Downregulation of MAPKs, c-Fos and NFATc1
Eun-Gyeong Lee, Hee-Jin Yun, Sang-Il Lee, Wan-Hee Yoo
Korean J Intern Med. 2010;25(1):93-100. Published online February 26, 2010
Background/AimsThe present study was performed to determine the effects of the ethyl acetate extract of Cudrania tricuspidata (EACT) on interleukin (IL)-1β-stimulated receptor activator of NF-κB ligand (RANKL)-mediated osteoclast differentiation.
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Original Article
Severe Pulmonary Adverse Effects in Lymphoma Patients Treated with Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) Regimen Plus Rituximab
Kyu-Hyoung Lim, Ho-Il Yoon, Young Ae Kang, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang, Jae Ho Lee, Choon-Taek Lee, Jong Seok Lee
Korean J Intern Med. 2010;25(1):86-92. Published online February 26, 2010
Background/AimsThe aim of our study was to determine the incidence and clinical features of severe pulmonary complications in patients receiving cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or rituximab plus CHOP (R-CHOP) as the initial treatment for lymph..
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Original Article
Ultrasonographic Features of Papillary Thyroid Carcinoma in Patients with Graves' Disease
Jin Ook Chung, Dong Hyeok Cho, Dong Jin Chung, Min Young Chung
Korean J Intern Med. 2010;25(1):71-76. Published online February 26, 2010
Background/AimsTo characterize ultrasonographic findings in papillary thyroid carcinoma (PTC) combined with Graves' disease. MethodsMedical records and ultrasonographic findings of 1,013 patients with Graves' disease and 3,380 patients without G..
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Original Article
Clinical Characteristics of Pulmonary Embolism with Underlying Malignancy
Ji Eun Lee, Hye-Ryoun Kim, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young-Soo Shim, Seok-Chul Yang
Korean J Intern Med. 2010;25(1):66-70. Published online February 26, 2010
Background/AimsThe risk of venous thromboembolism (VTE), which encompasses deep vein thrombosis and pulmonary embolism (PE), increases in patients with cancer. Anticancer treatment is also associated with an increased risk for VTE. We conducted this study to investigate the cl..
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Original Article
Clinical Meaning of Early Oxygenation Improvement in Severe Acute Respiratory Distress Syndrome under Prolonged Prone Positioning
Kwangha Lee, Mi-Young Kim, Jung-Wan Yoo, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh
Korean J Intern Med. 2010;25(1):58-65. Published online February 26, 2010
Background/AimsVentilating patients with acute respiratory distress syndrome (ARDS) in the prone position has been shown to improve arterial oxygenation, but prolonged prone positioning frequently requires continuous deep sedation, which may be harmful to patients. We evaluated..
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Original Article
Natural History and Renal Pathology in Patients with Isolated Microscopic Hematuria
Byung Soo Kim, Yong Kyun Kim, Young Shin Shin, Young Ok Kim, Ho Cheol Song, Yong Soo Kim, Euy Jin Choi
Korean J Intern Med. 2009;24(4):356-361. Published online November 27, 2009
Background/AimsNo definite conclusions have been reached about the natural history of patients with isolated microscopic hematuria (IMH). In this study, we observed the natural history of patients with IMH and examined factors related to a pathologic diagnosis and subsequent p..
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Original Article
Chest Computed Tomography (CT) Immediately after CT-Guided Transthoracic Needle Aspiration Biopsy as a Predictor of Overt Pneumothorax
Tae June Noh, Chang Hoon Lee, Young Ae Kang, Sung-Youn Kwon, Ho-Il Yoon, Tae Jung Kim, Kyung Won Lee, Jae Ho Lee, Choon-Taek Lee
Korean J Intern Med. 2009;24(4):343-349. Published online November 27, 2009
Background/AimsThis study examined the correlation between pneumothorax detected by immediate post-transthoracic needle aspiration-biopsy (TTNB) chest computed tomography (CT) and overt pneumothorax detected by chest PA, and investigated factors that might influence the correl..
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Original Article
Comparison of Sirolimus and Paclitaxel-Eluting Stents for Complex Coronary Lesions: An Intravascular Ultrasound Study
Yun-Kyeong Cho, Seung-Ho Hur, Hyun-Tae Kim, In-Cheol Kim, Hyoung-Seob Park, Hyuck-Jun Yoon, Chang-Wook Nam, Hyungseop Kim, Seong-Wook Han, Yoon-Nyun Kim, Kwon-Bae Kim
Korean J Intern Med. 2009;24(4):323-329. Published online November 27, 2009
Background/AimsRecent intravascular ultrasound (IVUS) studies of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) have demonstrated a significant reduction in neointimal hyperplasia (NIH) based on simple coronary lesions. In this study, we evaluated the effic..
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Review
Graft-versus-Leukemia Effect of Nonmyeloablative Stem Cell Transplantation
Masahiro Imamura, Junji Tanaka
Korean J Intern Med. 2009;24(4):287-298. Published online November 27, 2009
Nonmyeloablative stem cell transplantation (NST) is increasingly used with beneficial effects because it can be applied to older patients with hematological malignancies and those with various complications who are not suitable for conventional myeloablative stem cell transplantation (CST). Vario..
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Case Report
A Synonymous Genetic Alteration of LMX1B in a Family with Nail-Patella Syndrome
Joo Ho Ham, Seok Joon Shin, Kyu Re Joo, Sung Min Park, Hye Young Sung, Joong Seok Kim, Jin Soo Choi, Yeong Jin Choi, Ho Cheol Song, Eui Jin Choi
Korean J Intern Med. 2009;24(3):274-278. Published online August 26, 2009
The gene responsible for nail-patella syndrome, LMX1B, has recently been identified on chromosome 9q. Here we present a patient with nail-patella syndrome and an autosomal dominant pattern of inheritance. A 17-year-old girl visited our clinic for the evaluation and treatment of p..
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Original Article
Paraquat Intoxication in Subjects Who Attempt Suicide: Why They Chose Paraquat
Su-Jin Seok, Hyo-Wook Gil, Du-Shin Jeong, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2009;24(3):247-251. Published online August 26, 2009
Background/AimsParaquat (PQ) has been used in suicide attempts; an estimated 2,000 toxic ingestions occur annually, with 60-70% mortality. We sought to determine why PQ is such a common agent for suicide attempts in Korea. MethodsWe analyzed 250..
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