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Cardiology / Original Article
Serum levels of carbohydrate antigen 125 in combination with N-terminal pro-brain natriuretic peptide in patients with acute decompensated heart failure
Jae Yong Yoon, Dong Heon Yang, Hyun Jun Cho, Nam Kyun Kim, Chang-Yeon Kim, Jihyun Son, Jae-Hyung Roh, Se Yong Jang, Myung Hwan Bae, Jang Hoon Lee, Hun Sik Park, Yongkeun Cho, Shung Chull Chae
Korean J Intern Med. 2019;34(4):811-818. Published online December 31, 2018
Background/Aims: Carbohydrate antigen 125 (CA-125) is an emerging prognostic biomarker for heart failure. We aimed to test the long-term prognostic value of CA-125 in combination with N-terminal pro-brain natriuretic peptide (NT-proBNP) in patients with acute decompensated heart failure (ADHF).
Met..
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Nephrology / Original Article
Impact of sarcopenia on long-term mortality and cardiovascular events in patients undergoing hemodialysis
Jwa-Kyung Kim, Sung Gyun Kim, Ji-Eun Oh, Young-Ki Lee, Jung-Woo Noh, Hyung Jik Kim, Young Rim Song
Korean J Intern Med. 2019;34(3):599-607. Published online November 23, 2017
Background/Aims: A high body mass index (BMI) is known to correlate with better survival in patients on hemodialysis (HD). However, the impacts of body composition and sarcopenia on survival have not been well studied in this population.
Methods: One hundred and forty-two prevalent HD patients were..
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Infectious diseases / Original Article
Clinical and microbiological factors associated with early patient mortality from methicillin-resistant Staphylococcus aureus bacteremia
Tark Kim, Yong Pil Chong, Ki-Ho Park, Kyung Mi Bang, Su-Jin Park, Sung-Han Kim, Jin-Yong Jeong, Sang-Oh Lee, Sang-Ho Choi, Jun Hee Woo, Yang Soo Kim
Korean J Intern Med. 2019;34(1):184-194. Published online July 6, 2017
Background/Aims: Methicillin-resistant Staphylococcus aureus bacteremia (MRSAB) is a major bloodstream infection with a high mortality rate. Identification of factors associated with early mortality in MRSAB patients would be useful for predicting prognosis and developing new therapeutic opti..
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Cardiology / Review
Current status of acute myocardial infarction in Korea
Yongcheol Kim, Youngkeun Ahn, Myeong Chan Cho, Chong Jin Kim, Young Jo Kim, Myung Ho Jeong
Korean J Intern Med. 2019;34(1):1-10. Published online December 28, 2018
Coronary artery disease, especially acute myocardial infarction (AMI), is a leading cause of death in the Asia-Pacific region. The Korea Acute Myocardial Infarction Registry (KAMIR) is the first nationwide, prospective, multicenter registry of Korean patients with AMI. Since the KAMIR first began in..
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Pulmonology / Original Article
Effect of vitamin D deficiency in Korean patients with acute respiratory distress syndrome
[corrected-article]
Sojung Park, Min Gi Lee, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh, Jin Won Huh
Korean J Intern Med. 2018;33(6):1129-1136. Published online June 20, 2018
Background/Aims: Vitamin D modulates innate and adaptive immune responses, and vitamin D deficiency is associated with increased mortality in hospitalized patients with pneumonia. We evaluated the prevalence of vitamin D deficiency in Korean patients with acute respiratory distress syndrome (ARDS) a..
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Nephrology / Original Article
Predialysis hyponatremia and mortality in elderly patients beginning to undergo hemodialysis
Seon Ha Baek, Sejoong Kim, Ki Young Na, Suhnggwon Kim, Ho Jun Chin
Korean J Intern Med. 2018;33(5):970-979. Published online October 19, 2017
Background/Aims: Predialysis hyponatremia has been recently reported to be associated with mortality in incident hemodialysis patients. However, whether hyponatremia is associated with unfavorable outcomes in elderly patients remains unknown. We hypothesized that nephrology referral inf luences hypo..
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Gastroenterology / Original Article
Outcomes of patients treated with Sengstaken-Blakemore tube for uncontrolled variceal hemorrhage
Ja Yun Choi, Yun Won Jo, Sang Soo Lee, Wan Soo Kim, Hye Won Oh, Cha Young Kim, Eun Young Yun, Jin Joo Kim, Jae Min Lee, Hong Jun Kim, Hyun Jin Kim, Tae Hyo Kim, Woon Tae Jung, Ok Jae Lee, Rock Bum Kim
Korean J Intern Med. 2018;33(4):696-704. Published online November 10, 2017
Background/Aims: The aim of this study was to investigate the mortality, bleeding control rate, and their associated predictors in patients treated with Sengstaken-Blakemore (SB) tube for uncontrolled variceal hemorrhage associated with hemodynamic instability or failure of endoscopic treatment.
Me..
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Pulmonology / Original Article
The effect of an improvement of experience and training in extracorporeal membrane oxygenation management on clinical outcomes
Go-Woon Kim, Younsuck Koh, Chae-Man Lim, Jin Won Huh, Sung Ho Jung, Joon Bum Kim, Sang-Bum Hong
Korean J Intern Med. 2018;33(1):121-129. Published online March 25, 2016
Background/Aims: The use of extracorporeal membrane oxygenation (ECMO) is spreading rapidly, with successful procedures reported in the ECMO for Severe Adult Respiratory failure (CESAR) trial and treatment of the H1N1 pandemic. However, ECMO is associated with a high mortality rate. This study aimed..
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Nephrology / Original Article
The pattern of choosing dialysis modality and related mortality outcomes in Korea: a national population-based study
Hyung Jong Kim, Jung Tak Park, Seung Hyeok Han, Tae-Hyun Yoo, Hyeong-Cheon Park, Shin-Wook Kang, Kyoung Hoon Kim, Dong-Ryeol Ryu, Hyunwook Kim
Korean J Intern Med. 2017;32(4):699-710. Published online June 26, 2017
Background/Aims: Since comorbidities are major determinants of modality choice, and also interact with dialysis modality on mortality outcomes, we examined the pattern of modality choice according to comorbidities and then evaluated how such choices affected mortality in incident dialysis patients.
..
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Nephrology / Original Article
The impact of high serum bicarbonate levels on mortality in hemodialysis patients
Kyung Yoon Chang, Hyung Wook Kim, Woo Jeong Kim, Yong Kyun Kim, Su-Hyun Kim, Ho Chul Song, Young Ok Kim, Dong Chan Jin, Euy Jin Choi, Chul Woo Yang, Yong-Lim Kim, Nam-Ho Kim, Shin-Wook Kang, Yon-Su Kim, Young Soo Kim
Korean J Intern Med. 2017;32(1):109-116. Published online April 5, 2016
Background/Aims: The optimal serum bicarbonate level is controversial for patients who are undergoing hemodialysis (HD). In this study, we analyzed the impact of serum bicarbonate levels on mortality among HD patients. Methods: Prevalent HD patients were selected from the Clinical Research Center re..
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Nephrology / Original Article
The impact of blood flow rate during hemodialysis on all-cause mortality
Kyung Yoon Chang, Su-Hyun Kim, Young Ok Kim, Dong Chan Jin, Ho Chul Song, Euy Jin Choi, Yong-Lim Kim, Yon-Su Kim, Shin-Wook Kang, Nam-Ho Kim, Chul Woo Yang, Yong Kyun Kim
Korean J Intern Med. 2016;31(6):1131-1139. Published online February 22, 2016
Background/Aims: Inadequacy of dialysis is associated with morbidity and mortality in chronic hemodialysis (HD) patients. Blood flow rate (BFR) during HD is one of the important determinants of increasing dialysis dose. However, the optimal BFR is unclear. In this study, we investigated the impact o..
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Nephrology / Original Article
Liver cirrhosis leads to poorer survival in patients with end-stage renal disease
Ae Jin Kim, Hye Jin Lim, Han Ro, Ji Yong Jung, Hyun Hee Lee, Wookyung Chung, Jae Hyun Chang
Korean J Intern Med. 2016;31(4):730-738. Published online March 26, 2016
Background/Aims: Liver cirrhosis (LC) is an important problem in patients withend-stage renal disease (ESRD). Few studies have investigated the inf luence ofLC on mortality in patients with ESRD. This study investigated the associationbetween LC and mortality among patients with ESRD and compare mor..
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Cardiology / Original Article
Clinical significance of changes in the corrected QT interval in stress-induced cardiomyopathy
Jung-Hee Lee, Jae-Sun Uhm, Dong Geum Shin, Boyoung Joung, Hui-Nam Pak, Young-Guk Ko, Geu-Ru Hong, Moon-Hyoung Lee
Korean J Intern Med. 2016;31(3):507-516. Published online April 7, 2016
Background/Aims: Although transient changes in the electrocardiogram (ECG) of patients with stress-induced cardiomyopathy (SCMP) are common, there are little data about ECG changes in patients with SCMP and the clinical implications of these variations.
Methods: We investigated a total of 128 pati..
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Cardiology / Original Article
Angiotensin II type 1 receptor blockers as a first choice in patients with acute myocardial infarction
Jang Hoon Lee, Myung Hwan Bae, Dong Heon Yang, Hun Sik Park, Yongkeun Cho, Won Kee Lee, Myung Ho Jeong, Young Jo Kim, Myeong Chan Cho, Chong Jin Kim, Shung Chull Chae, Korea Acute Myocardial Infarction Registry Investigators
Korean J Intern Med. 2016;31(2):267-276. Published online December 23, 2015
Background/Aims: Angiotensin II type 1 receptor blockers (ARBs) have not been adequately evaluated in patients without left ventricular (LV) dysfunction or heart failure after acute myocardial infarction (AMI).
Methods: Between November 2005 and January 2008, 6,781 patients who were not receiving a..
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Gastroenterology / Original Article
Predictive factors of mortality within 30 days in patients with nonvariceal upper gastrointestinal bleeding
Yoo Jin Lee, Bo Ram Min, Eun Soo Kim, Kyung Sik Park, Kwang Bum Cho, Byoung Kuk Jang, Woo Jin Chung, Jae Seok Hwang, Seong Woo Jeon
Korean J Intern Med. 2016;31(1):54-64. Published online December 28, 2015
Background/Aims: Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a common medical emergency that can be life threatening. This study evaluated predictive factors of 30-day mortality in patients with this condition.
Methods: A prospective observational study was conducted at a single hospita..
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Pulmonology / Original Article
Clinical characteristics of nursing home-acquired pneumonia in elderly patients admitted to a Korean teaching hospital
Seong Joo Koh, Jong Hoo Lee
Korean J Intern Med. 2015;30(5):638-647. Published online August 27, 2015
Background/Aims: Nursing home-acquired pneumonia (NHAP) is included under healthcare-associated pneumonia. However, the optimal treatment strategy for NHAP has been controversial in several studies. We evaluated the clinical features of NHAP compared to community-acquired pneumonia (CAP) in elderly ..
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Pulmonology / Original Article
Clinical outcomes of extracorporeal membrane oxygenation support in patients with hematologic malignancies
Hye Seon Kang, Chin Kook Rhee, Hea Yon Lee, Young Kyoon Kim, Soon Seog Kwon, Seok Chan Kim, Jong Wook Lee
Korean J Intern Med. 2015;30(4):478-488. Published online June 29, 2015
Background/Aims: The clinical outcomes of patients with hematologic malignancies who were treated with extracorporeal membrane oxygenation (ECMO) after the failu re of optimal conventional therapy were determined.
Methods: The medical records of all patients administered ECMO during their stay in a..
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Rheumatology / Original Article
Pulmonary hypertension in systemic lupus erythematosus: an independent predictor of patient survival
Hong Ki Min, Jae Ho Lee, Seung Min Jung, Jennifer Lee, Kwi Young Kang, Seung-Ki Kwok, Ji Hyeon Ju, Kyung-Su Park, Sung-Hwan Park
Korean J Intern Med. 2015;30(2):232-241. Published online February 27, 2015
Background/Aims: We investigated whether transthoracic echocardiography-suspected pulmonary hypertension (PH) affects survival in systemic lupus erythematosus (SLE) patients and examined factors associated with PH occurrence and survival.
Methods: This retrospective single-center study included 154..
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Infectious diseases / Original Article
Clinical and microbiological features of Providencia bacteremia: experience at a tertiary care hospital
Hee Kyoung Choi, Young Keun Kim, Hyo Youl Kim, Jeong Eun Park, Young Uh
Korean J Intern Med. 2015;30(2):219-225. Published online February 27, 2015
Background/Aims: Providencia species frequently colonize urinary catheters and cause urinary tract infections (UTIs); however, bacteremia is uncommon and not well understood. We investigated the clinical features of Providencia bacteremia and the antibiotic susceptibility of Provide..
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Nephrology / Original Article
Relationship between duration of hospital-acquired acute kidney injury and mortality: a prospective observational study
Jinyoung Yoo, Ji Sung Lee, Jiyeon Lee, Jin Seok Jeon, Hyunjin Noh, Dong Cheol Han, Soon Hyo Kwon
Korean J Intern Med. 2015;30(2):205-211. Published online February 27, 2015
Background/Aims: New definitions of acute kidney injury (AKI) have recently emerged. Some studies have suggested that duration of AKI is an additional predictive parameter for mortality. Here, we evaluated whether AKI duration was predictive of long-term mortality in patients with hospital-acquired ..
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