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Original Article
Gender Differences in Susceptibility to Smoking among Patients with Lung Cancer
Jeong-Seon Ryu, Sang-Hoon Jeon, Jung-Soo Kim, Jung Hwan Lee, Seong Hyun Kim, Ji Taek Hong, Ju Hong Jeong, Ji Joong Jeong, Myung Dong Lee, Sang Joon Min, Hae-Seong Nam, Jae-Hwa Cho, Seung-Min Kwak, Hong Lyeol Lee, Hyun-Jung Kim
Korean J Intern Med. 2011;26(4):427-431. Published online November 28, 2011
Background/AimsTo determine whether female smokers are more or less susceptible to the detrimental pulmonary-function effects of smoking when compared to male smokers among patients with lung cancer. MethodsPack-years and pulmonary function indi..
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Original Article
Sleep Disorder and Cardiovascular Risk Factors among Patients with Type 2 Diabetes Mellitus
Unjin Shim, Hyejin Lee, Jee-Young Oh, Yeon-Ah Sung
Korean J Intern Med. 2011;26(3):277-284. Published online September 13, 2011
Background/AimsSleep disorder (SD) is associated with an increased risk of cardiovascular disease and is more prevalent among individuals with type 2 diabetes mellitus. These health problems not only frequently coexist but also exacerbate each other. We conducted a cross-secti..
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Original Article
Diagnostic Value of a Chimeric TSH Receptor (Mc4)-Based Bioassay for Graves' Disease
Ji In Lee, Hye Won Jang, Soo Kyoung Kim, Joon Young Choi, Ji Young Kim, Kyu Yeon Hur, Jae Hyeon Kim, Yong-Ki Min, Jae Hoon Chung, Sun Wook Kim
Korean J Intern Med. 2011;26(2):179-186. Published online June 1, 2011
Background/AimsGraves' disease (GD) is caused by thyroid-stimulating hormone receptor (TSHR) and thyroid-stimulating immunoglobulin (TSI). We used a recently introduced, technically enhanced TSI bioassay to assess its diagnostic value and determine the cut-off in patients in h..
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Original Article
Two-Year Clinical Outcome after Carvedilol-Loaded Stent Implantation in Patients with Coronary Artery Disease
Hyun Kuk Kim, Young Joon Hong, Myung Ho Jeong, Weon Kim, Sung Soo Kim, Jum Suk Ko, Min Goo Lee, Doo Sun Sim, Keun Ho Park, Nam Sik Yoon, Hyun Ju Yoon, Kye Hun Kim, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Jeong Gwan Cho, Jong Chun Park, Jung Chaee Kang
Korean J Intern Med. 2011;26(1):41-46. Published online March 2, 2011
Background/AimsCarvedilol is an antioxidant that inhibits smooth muscle cell proliferation and migration. The aim of this study was to investigate the beneficial effects of carvedilol-loaded stents on 2-year clinical outcomes after stent implantation in patients with coronary ..
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Case Report
Thalidomide Induced Nonspecific Interstitial Pneumonia in Patient with Relapsed Multiple Myeloma
Myung-Hee Kang, Ji-Hyun Ju, Hoon-Gu Kim, Jung Hun Kang, Kyung-Nyeo Jeon, Ho-Cheol Kim, Gyeong-Won Lee
Korean J Intern Med. 2010;25(4):447-449. Published online November 27, 2010
A 63-year-old female diagnosed with relapsed multiple myeloma visited our hospital complaining of a persistent cough. Since July 2006, she had been taking 100 mg thalidomide daily and gradually developed shortness of breath and a persistent dry cough. A chest X-ray and computed tomography showed ..
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Original Article
Serum Globotriaosylceramide Assay as a Screening Test for Fabry Disease in Patients with ESRD on Maintenance Dialysis in Korea
Jeong-Yup Kim, Young-Youl Hyun, Ji-Eun Lee, Hye-Ran Yoon, Gu-Hwan Kim, Han-Wook Yoo, Seong-Tae Cho, No-Won Chun, Byoung-Chunn Jeoung, Hwa-Jung Kim, Keong-Wook Kim, Seong-Nam Kim, Yung-A Kim, Hyun-Ah Lee, Jong-Young Lee, Yung-Chun Lee, Hun-Kwan Lim, Keong-Sik Oh, Seong-Hwan Son, Beong-Hee Yu, Kyeong-So Wee, Eun-Jong Lee, Young-Ki Lee, Jung-Woo Noh, Seung-Jung Kim, Kyu-Bok Choi, Suk-Hee Yu, Heui-Jung Pyo, Young-Joo Kwon
Korean J Intern Med. 2010;25(4):415-421. Published online November 27, 2010
Background/AimsFabry disease is an X-linked recessive and progressive disease caused by α-galactosidase A (α-GaL A) deficiency. We sought to assess the prevalence of unrecognized Fabry disease in dialysis-dependent patients and the efficacy of serum globotriaosylceramide (GL..
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Original Article
Correlation of Anti-Cyclic Citrullinated Antibody with Hand Joint Erosion Score in Rheumatoid Arthritis Patients
Hyun Hee Kim, JiHun Kim, Sung-Hoon Park, Seong-Kyu Kim, Ok-Dong Kim, Jung-Yoon Choe
Korean J Intern Med. 2010;25(2):201-206. Published online June 1, 2010
Background/AimsTo examine the correlation between radiological joint damage and serological parameters in early rheumatoid arthritis (RA). MethodsThis retrospective study reviewed the records of 216 patients diagnosed with RA and classified them..
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Original Article
Severe Pulmonary Adverse Effects in Lymphoma Patients Treated with Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) Regimen Plus Rituximab
Kyu-Hyoung Lim, Ho-Il Yoon, Young Ae Kang, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang, Jae Ho Lee, Choon-Taek Lee, Jong Seok Lee
Korean J Intern Med. 2010;25(1):86-92. Published online February 26, 2010
Background/AimsThe aim of our study was to determine the incidence and clinical features of severe pulmonary complications in patients receiving cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or rituximab plus CHOP (R-CHOP) as the initial treatment for lymph..
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Original Article
Ultrasonographic Features of Papillary Thyroid Carcinoma in Patients with Graves' Disease
Jin Ook Chung, Dong Hyeok Cho, Dong Jin Chung, Min Young Chung
Korean J Intern Med. 2010;25(1):71-76. Published online February 26, 2010
Background/AimsTo characterize ultrasonographic findings in papillary thyroid carcinoma (PTC) combined with Graves' disease. MethodsMedical records and ultrasonographic findings of 1,013 patients with Graves' disease and 3,380 patients without G..
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Original Article
Prevalence of Depression and Anxiety in Outpatients with Chronic Airway Lung Disease
Yon Ju Ryu, Eun-Mi Chun, Jin Hwa Lee, Jung Hyun Chang
Korean J Intern Med. 2010;25(1):51-57. Published online February 26, 2010
Background/AimsPatients with chronic airway lung diseases often experience depression and anxiety, but little information is available regarding Koreans with these conditions. We thus assessed depression and anxiety in Korean patients with chronic airway lung diseases.
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Original Article
Clinical Value of Serum Uric Acid in Patients with Suspected Coronary Artery Disease
Hong Euy Lim, Seong Hwan Kim, Eung Ju Kim, Jin Won Kim, Seung Woon Rha, Hong Seog Seo, Chang Gyu Park
Korean J Intern Med. 2010;25(1):21-26. Published online February 26, 2010
Background/AimsAlthough increased serum uric acid (SUA) concentrations are commonly encountered in patients with risk factors for coronary artery disease (CAD), the clinical value of SUA has not been established. MethodsThe study group comprised..
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Original Article
Serum C-Reactive Protein Levels in Normal-Weight Polycystic Ovary Syndrome
Ji Young Oh, Ji-Ah Lee, Hyejin Lee, Jee-Young Oh, Yeon-Ah Sung, Hyewon Chung
Korean J Intern Med. 2009;24(4):350-355. Published online November 27, 2009
Background/AimsSerum levels of highly sensitive C-reactive protein (hsCRP), a vascular inflammatory marker, may predict the development of cardiovascular disease (CVD) and type 2 diabetes. Women with polycystic ovary syndrome (PCOS) are at greater risk for type 2 diabetes and ..
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Original Article
Comparison of Sirolimus and Paclitaxel-Eluting Stents for Complex Coronary Lesions: An Intravascular Ultrasound Study
Yun-Kyeong Cho, Seung-Ho Hur, Hyun-Tae Kim, In-Cheol Kim, Hyoung-Seob Park, Hyuck-Jun Yoon, Chang-Wook Nam, Hyungseop Kim, Seong-Wook Han, Yoon-Nyun Kim, Kwon-Bae Kim
Korean J Intern Med. 2009;24(4):323-329. Published online November 27, 2009
Background/AimsRecent intravascular ultrasound (IVUS) studies of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) have demonstrated a significant reduction in neointimal hyperplasia (NIH) based on simple coronary lesions. In this study, we evaluated the effic..
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Review
Graft-versus-Leukemia Effect of Nonmyeloablative Stem Cell Transplantation
Masahiro Imamura, Junji Tanaka
Korean J Intern Med. 2009;24(4):287-298. Published online November 27, 2009
Nonmyeloablative stem cell transplantation (NST) is increasingly used with beneficial effects because it can be applied to older patients with hematological malignancies and those with various complications who are not suitable for conventional myeloablative stem cell transplantation (CST). Vario..
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Original Article
Significance of Inflammatory Markers in Diabetic Patients with Stable Coronary Artery Disease
Hyo-Jin Lee, Sung-Ho Her, Yun-Sun Im, Kang-Yeon Won, Sun-Hong Yoo, Dong-Bin Kim, Dong-Il Shin, Pum-Joon Kim, Ki-Bae Seung, Jae-Hyung Kim, Keon-Yeop Kim
Korean J Intern Med. 2009;24(3):212-219. Published online August 26, 2009
Background/AimsPatients with diabetes are prone to coronary artery disease (CAD); however, the majority of diabetic patients show normal coronary arteries. We examined differences in the clinical aspects of diabetic patients with insignificant and with significant stenosis of ..
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Original Article
Early Detection Of Asymptomatic Coronary Artery Disease In Patients With Type 2 Diabetes Mellitus
Won Sang Yoo, Hee Jin Kim, Dohee Kim, Myung Yong Lee, Hyun-Kyung Chung
Korean J Intern Med. 2009;24(3):183-189. Published online August 26, 2009
Background/AimsIn type 2 diabetic patients, coronary artery disease (CAD) is usually detected at an advanced stage due to a lack of symptoms. The aim of this study was to define which clinical parameters or non-invasive tests predict CAD in asymptomatic type 2 diabetic patients..
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Review
Autosomal Dominant Polycystic Kidney Disease: 2009 Update for Internists
William M. Bennett
Korean J Intern Med. 2009;24(3):165-168. Published online August 26, 2009
Because autosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic abnormalities seen in today's medical practice, many internists will likely treat patients affected by this condition. Genetic abnormalities have been increasingly recognized, and the pathophysiology of..
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Case Report
Acute Fibrinous and Organizing Pneumonia Following Hematopoietic Stem Cell Transplantation
Sang Min Lee, Jae-Jung Park, Sun Hee Sung, Yookyung Kim, Kyoung Eun Lee, Yeung-Chul Mun, Soon Nam Lee, Chu Myong Seong
Korean J Intern Med. 2009;24(2):156-159. Published online June 8, 2009
A 60-year-old man presented with cough, sputum, and dyspnea. He had a history of acute myeloid leukemia and hematopoietic stem cell transplantation with chronic renal failure. Chest CT scans showed miliary nodules and patchy consolidations. Histological examination revealed numerous fibrin balls ..
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Case Report
Acute Embolic Occlusion of the Left Common Iliac Artery Treated With Intra-Arterial Thrombolysis and Percutaneous Thrombectomy
Wang-Soo Lee, Kwang Je Lee, Wang Seong Ryu
Korean J Intern Med. 2009;24(2):153-155. Published online June 8, 2009
Acute embolic occlusion of the common iliac artery is a rare medical emergency that is not only limb-threatening, but also potentially life-threatening. Several treatment options exist for acute limb ischemia, although no treatment is clearly best. We report a case of acute embolic occlusion of t..
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Original Article
The Effect of Residual Renal Function at the Initiation of Dialysis on Patient Survival
Seoung Gu Kim, Nam Ho Kim
Korean J Intern Med. 2009;24(1):55-62. Published online March 6, 2009
Background/AimsThe optimal time point for initiating renal replacement therapy in patients with end-stage renal disease remains controversial. The primary objective of our study was to determine the effects of residual renal function at the beginning of renal replacement thera..
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