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Cardiology / Original Article
Sex-specific impact of the COVID-19 outbreak on the incidence of metabolic syndrome: a comparative study of 2018–2019 and 2020–2021
Kyeong-Hyeon Chun, Hyun-Jin Kim, Dae Ryong Kang, Jang Young Kim, Wonjin Kim, Yong Whi Jeong, Seung Hwan Han, Kwang Kon Koh; on behalf of the Taskforce Team of the Metabolic Syndrome Fact Sheet of the Korean Society of Cardiometabolic Syndrome
Korean J Intern Med. 2025;40(2):262-274. Published online March 1, 2025
Background/Aims: The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted global health, exacerbated metabolic health issues, and altered lifestyle behaviors. This study examined the sex-specific impact of the COVID-19 outbreak on the incidence of metabolic syndrome using data fro..
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Cardiology / Review
Sex differences in diagnosis and treatment of heart failure: toward precision medicine
Soo Yong Lee, Seong-Mi Park
Korean J Intern Med. 2025;40(2):196-207. Published online March 1, 2025
There are sex-related differences in the pathophysiology and phenotype of heart failure (HF) as well as the pharmacokinetics and pharmacodynamics of drugs between women and men due to biological differences, such as heart and vessel size, response to blood volume and pressure, body water and muscle ..
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Pulmonology / Original Article
Sex differences in chronic obstructive pulmonary disease characteristics: the Korea National Health and Nutrition Examination Survey 2007–2018
Moon Seong Baek, Haegwang Shin, Kang-Mo Gu, Hae In Jung, Won Young Kim, Jae-Woo Jung, Jong-Wook Shin, Sun-Young Jung, Jae-Yeol Kim
Korean J Intern Med. 2024;39(1):137-147. Published online December 14, 2023
Background/Aims: Chronic obstructive pulmonary disease (COPD) is less prevalent in females than males, but it affects mortality in females. There may be sex differences in the clinical characteristics of COPD.
Methods: We analyzed the Korea National Health and Nutrition Examination Survey dataset f..
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Cardiology / Original Article
Sex differences in clinical characteristics and long-term outcome in patients with heart failure: data from the KorAHF registry
Hyue Mee Kim, Hack-Lyoung Kim, Myung-A Kim, Hae-Young Lee, Jin Joo Park, Dong-Ju Choi; on the behalf of the KorAHF Investigators
Korean J Intern Med. 2024;39(1):95-109. Published online December 14, 2023
Background/Aims: Sex differences in the prognosis of heart failure (HF) have yielded inconsistent results, and data from Asian populations are even rare. This study aimed to investigate sex differences in clinical characteristics and long-term prognosis among Korean patients with HF.
Methods: A tot..
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Hemato-oncology / Original Article
Physical activity of Korean cancer survivors is associated with age and sex
Jae Hyeon Park, Jung Soo Lee, Yoon Ho Ko, Yeo Hyung Kim
Korean J Intern Med. 2021;36(Suppl 1):S225-S234. Published online May 7, 2020
Background/Aims: This study aimed to assess adherence to physical activity guidelines in cancer survivors and to investigate related factors.
Methods: The cross-sectional data of 39,845 community-dwelling participants aged ≥ 20 years (1,254 cancer survivors) in the Korea National Health and Nutri..
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Cardiology / Original Article
Sex differences in long-term clinical outcomes of acute myocardial infarction according to the presence of diabetes mellitus
Yu Ri Kim, Myung Ho Jeong, Youngkeun Ahn, Ju Han Kim, Young Joon Hong, Min Chul Kim, Kyung Hoon Cho, Xiong Yi Han; other KAMIR-NIH Registry Investigators
Korean J Intern Med. 2021;36(Suppl 1):S99-S113. Published online January 12, 2021
Background/Aims: This study compared long-term clinical outcomes between male and female acute myocardial infarction (AMI) patients with and without diabetes mellitus (DM).
Methods: From November 2011 to December 2015, 13,104 patients with AMI were enrolled in the Korea Acute Myocardial Infarction ..
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Gastroenterology / Original Article
Sex difference in bowel preparation quality and colonoscopy time
Young-Jae Hwang, Dong Woo Shin, Nayoung Kim, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Dong Ho Lee
Korean J Intern Med. 2021;36(2):322-331. Published online June 22, 2020
Background/Aims: The length of colon is known to be longer in females than in males. In addition, the morphology of colon cancer is different between males and females. The aim of this study was to investigate sex differences in Boston bowel preparation score (BBPS) and colonoscopy insertion time.
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Cardiology / Original Article
J-curve relationship between corrected QT interval and mortality in acute heart failure patients
Chan Soon Park, Hyun-Jai Cho, Eue-Keun Choi, Sang Eun Lee, Min-Seok Kim, Jae-Joong Kim, Jin-Oh Choi, Eun-Seok Jeon, Kyung-Kuk Hwang, Shung Chull Chae, Sang Hong Baek, Seok-Min Kang, Byungsu Yoo, Dong-Ju Choi, Youngkeun Ahn, Kye-Hoon Kim, Myeong-Chan Cho, Byung-Hee Oh, Hae-Young Lee
Korean J Intern Med. 2020;35(6):1371-1384. Published online May 8, 2020
Background/Aims: This study investigated the prognostic power of corrected QT (QTc) interval in patients with acute heart failure (AHF) according to sex.
Methods: We analyzed multicenter Korean Acute Heart Failure registry with patients with AHF admitted from 2011 to 2014. Among them, we analyzed 4..
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Cardiology / Original Article
Gender differences in the presentation of chest pain in obstructive coronary artery disease: results from the Korean Women’s Chest Pain Registry
Dong-Hyuk Cho, Jimi Choi, Mi-Na Kim, Hack-Lyoung Kim, Yong Hyun Kim, Jin Oh Na, Jin-Ok Jeong, Hyun Ju Yoon, Mi-Seung Shin, Myung-A Kim, Kyung-Soon Hong, Gil Ja Shin, Seong-Mi Park, Wan Joo Shim
Korean J Intern Med. 2020;35(3):582-592. Published online March 19, 2019
Background/Aims: Chest pain in patients with obstructive coronary artery disease (OCAD) is affected by several social factors. The gender-based differences in chest pain among Koreans have yet to be investigated.
Methods: The study consecutively enrolled 1,549 patients (male/female, 514/1,035; 61 ..
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Cardiology / Original Article
Gender difference in the association between brachial-ankle pulse wave velocity and cardiovascular risk scores
Tae-Min Rhee, Hack-Lyoung Kim, Sohee Oh, Woo-Hyun Lim, Jae-Bin Seo, Woo-Young Chung, Sang-Hyun Kim, Myung-A Kim, Joo-Hee Zo
Korean J Intern Med. 2019;34(3):539-548. Published online March 16, 2018
Background/Aims: Although brachial-ankle pulse wave velocity (baPWV) has been validated as a novel method to predict the cardiovascular risk in general population, the relevance of baPWV to the traditional risk scores has not been clearly revealed. This study investigated the relationship between b..
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Cardiology / Original Article
Diagnostic accuracy of manual office blood pressure measurement in ambulatory hypertensive patients in Korea
Sehun Kim, Jin Joo Park, Seung-Ah Lee, Youngjin Cho, Yeonyee E. Yoon, Il-Young Oh, Chang-Hwan Yoon, Jung-Won Suh, Young-Seok Cho, Tae-Jin Youn, Goo-Yeong Cho, In-Ho Chae, Hae-Young Lee, Jinho Shin, Sungha Park, Dong-Ju Choi
Korean J Intern Med. 2018;33(1):113-120. Published online June 7, 2017
Background/Aims: Currently, office blood pressure (OBP) is the most widely used method of measuring blood pressure (BP) in daily clinical practice. However, data on the diagnostic accuracy of OBP in reference to ambulatory blood pressure (ABP) are scarce in Korea.
Methods: In retrospective and prospec..
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Rheumatology / Original Article
Clinical characteristics of male and female Korean patients with systemic lupus erythematosus: a comparative study
Jiwon Hwang, Jaejoon Lee, Joong Kyoung Ahn, Eun-Jung Park, Hoon-Suk Cha, Eun-Mi Koh
Korean J Intern Med. 2015;30(2):242-249. Published online February 27, 2015
Background/Aims: To compare the clinical characteristics and outcomes of systemic lupus erythematosus between male and female Korean patients.
Methods: A retrospective analysis was performed at a single tertiary hospital from August 1994 to May 2010. Male patients were matched with two to three fem..
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Endocrinology-metabolism / Original Article
Gender disparity in the secular trends for obesity prevalence in Korea: analyses based on the KNHANES 1998-2009
Sang Youl Rhee, Seok Won Park, Dae Jung Kim, Jeongtaek Woo
Korean J Intern Med. 2013;28(1):29-34. Published online December 28, 2012
Background/AimsA similar gender-associated trend in obesity is observed worldwide. Nevertheless, systematic analyses of gender-specific characteristics in the general Korean population are rare. MethodsWe analyzed the prevalence of obesity in Ko..
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