Hemato-oncology
Mutations in genes affecting DNA methylation enhances responses to decitabine in patients with myelodysplastic syndrome
Hyun Ae Jung, Chul Won Jung, Jun Ho Jang
Korean J Intern Med. 2021;36(2):413-423. Published online October 23, 2020
Background/Aims: In this study, we tested whether mutations in the methylation pathway genes ten-eleven-translocation 2 (TET2) and DNA methyltransferase gene 3A (DNMT3A) improve the responses of patients with myelodysplastic syndrome (MDS) to decitabine.
Methods: We retrospectively se..
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Rheumatology
Mutation of ten-eleven translocation-2 is associated with increased risk of autoimmune disease in patients with myelodysplastic syndrome
Yoon-Jeong Oh, Dong-Yeop Shin, Sang Mee Hwang, Sung-Min Kim, Kyongok Im, Hee Sue Park, Jung-Ah Kim, Yeong Wook Song, Ana Márquez, Javier Martín, Dong-Soon Lee, Jin Kyun Park
Korean J Intern Med. 2020;35(2):457-464. Published online October 25, 2019
Background/Aims: Myelodysplastic syndrome (MDS) is caused by genetic and epigenetic alteration of hematopoietic precursors and immune dysregulation. Approximately 20% of patients with MDS develop an autoimmune disease (AID). Here, we investigated whether particular genetic mutations are associated w..
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Hemato-oncology
Expression and prognostic significance of microRNAs in Korean patients with myelodysplastic syndrome
Yunsuk Choi, Eun-Hye Hur, Ju Hyun Moon, Bon-Kwan Goo, Dae Ro Choi, Je-Hwan Lee
Korean J Intern Med. 2019;34(2):390-400. Published online November 15, 2017
Background/Aims: Various alterations of microRNA (miRNA) expression have been reported in myelodysplastic syndrome (MDS). We aimed to investigate the unique patterns and prognostic significance of miRNA expression in Korean patients with MDS.
Methods: Bone marrow mononuclear cells were collected fr..
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First Korean case of Emberger syndrome (primary lymphedema with myelodysplasia) with a novel GATA2 gene mutation
Sang Kyung Seo, Kyu Yeun Kim, Seo Ae Han, Joon Seok Yoon, Sang-Yong Shin, Sang Kyun Sohn, Joon Ho Moon
Korean J Intern Med. 2016;31(1):188-190. Published online December 28, 2015
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Successful treatment of myelodysplastic
syndrome and Behcet colitis after allogeneic
hematopoietic stem cell transplantation
Min-Ha Kook, Ho-Young Yhim, Na-Ri Lee, Eun-Kee Song, Hee Sun Kim, Chang-Yeol Yim, Jae-Yong Kwak
Korean J Intern Med. 2014;29(1):123-125. Published online January 2, 2014
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A Case of Erythema Nodosum and Serositis Associated with Myelodysplastic Syndrome
Jung-Hye Choi, Myung-Ju Ahn, Yong-Wook Park, Ho-Suk Oh, Young-Yeul Lee, In-Soon Kim
Korean J Intern Med. 2005;20(2):177-179. Published online June 30, 2005
Myelodysplastic syndrome (MDS) is a heterogenous group of stem cell disorders usually characterized by progressive refractory cytopenias, which could progress to acute myeloid leukemia. MDS may be associated with a wide spectrum of skin lesions, including neoplastic cell infiltration, Sweet's syn..
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