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Endocrinology-metabolism
Incidence and risk factors for osteoporotic fractures in patients with systemic lupus erythematosus versus matched controls
Chang Seong Kim, Kyung-Do Han, Jin Hyung Jung, Hong Sang Choi, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
Korean J Intern Med. 2021;36(1):154-163. Published online June 26, 2019
Background/Aims: Despite recent improvements in the quality of life of patients with systemic lupus erythematosus (SLE), osteoporosis, and osteoporotic fractures are one of the major complications of SLE. Furthermore, limited data are available on the incidence and predictor of osteoporotic fracture..
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Nephrology
Trend of prevalence and incidence of systemic lupus erythematosus in South Korea, 2005 to 2015: a nationwide population-based study
Eun Hui Bae, Sang Yeob Lim, Kyung-Do Han, Jin-Hyung Jung, Hong Sang Choi, Ha Yeon Kim, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim
Korean J Intern Med. 2020;35(3):652-661. Published online June 21, 2019
Background/Aims: The aim of this study was to evaluate the trend of incidence and prevalence of systemic lupus erythematosus (SLE) in South Korea from 2005 to 2015.
Methods: From 2005 to 2015, individuals with SLE were identified from the National Health Insurance database, which records informatio..
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Rheumatology
The evaluation of cellular immune function in elderly patients with systemic lupus erythematosus
Kun Men, Yu Chen, Jingwei Zhang, Dianjun Wei
Korean J Intern Med. 2019;34(4):932-937. Published online November 29, 2017
Background/Aims: To evaluate cellular immune function in systemic lupus erythematosus (SLE) patients over 60 years old, the association between antinuclear antibody (ANA) titers and the ratio of CD4+ /CD8+ was analyzed in this study. The distribution of ANAs and extractable nu..
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Clinical features and prognoses of acute transverse myelitis in patients with systemic lupus erythematosus
Soo Min Ahn, Seokchan Hong, Doo-Ho Lim, Byeongzu Ghang, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo
Korean J Intern Med. 2019;34(2):442-451. Published online January 5, 2018
Background/Aims: Acute transverse myelitis (ATM) is a severe complication of systemic lupus erythematosus (SLE). This study evaluated the clinical factors related to outcome in patients with SLE-associated ATM.
Methods: The medical records of patients diagnosed with SLE-associated ATM between Janu..
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Infection in systemic lupus erythematosus, similarities, and differences with lupus flare
Ju-Yang Jung, Chang-Hee Suh
Korean J Intern Med. 2017;32(3):429-438. Published online April 28, 2017
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse manifestations, and its pathogenesis is unclear and complicated. Infection and SLE are similar in that they both cause inf lammatory reactions in the immune system; however, one functions to protect the body, whereas the..
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A neurometabolite study of chronic daily headache in patients with systemic lupus erythematosus using magnetic resonance spectroscopy: comparison with fibromyalgia patients and healthy controls
Chang-Nam Son, Sang-Hyon Kim, Hyuk Won Chang, Ji-Min Kim
Korean J Intern Med. 2016;31(6):1171-1177. Published online March 25, 2016
Background/Aims: Neuropsychiatric systemic lupus erythematosus (SLE) includes a broad spectrum of neurologic and psychiatric manifestations. One of the most commonly observed neuropsychiatric symptoms is headache. However, the lack of specific clinical distinctions for headache in SLE has made it di..
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Factors related to outcomes in lupus-related protein-losing enteropathy
Doo-Ho Lim, Yong-Gil Kim, Seung-Hyeon Bae, Soomin Ahn, Seokchan Hong, Chang-Keun Lee, Bin Yoo
Korean J Intern Med. 2015;30(6):906-912. Published online October 30, 2015
Background/Aims: Protein-losing enteropathy (PLE), characterized by severe hypoalbuminemia and peripheral edema, is a rare manifestation of systemic lupus erythematosus. This present study aimed to identify the distinctive features of lupus-related PLE and evaluate the factors related to the treatme..
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Pulmonary hypertension in systemic lupus erythematosus: an independent predictor of patient survival
Hong Ki Min, Jae Ho Lee, Seung Min Jung, Jennifer Lee, Kwi Young Kang, Seung-Ki Kwok, Ji Hyeon Ju, Kyung-Su Park, Sung-Hwan Park
Korean J Intern Med. 2015;30(2):232-241. Published online February 27, 2015
Background/Aims: We investigated whether transthoracic echocardiography-suspected pulmonary hypertension (PH) affects survival in systemic lupus erythematosus (SLE) patients and examined factors associated with PH occurrence and survival.
Methods: This retrospective single-center study included 154..
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Type B insulin-resistance syndrome presenting as autoimmune hypoglycemia, associated with systemic lupus erythematosus and interstitial lung disease
Seon Mee Kang, Heung Yong Jin, Kyung Ae Lee, Ji Hyun Park, Hong Sun Baek, Tae Sun Park
Korean J Intern Med. 2013;28(1):98-102. Published online December 28, 2012
We describe an unusual case of systemic lupus erythematosus with pulmonary manifestations presenting as hypoglycemia due to anti-insulin receptor antibodies. A 38-year-old female suffered an episode of unconsciousness and was admitted to hospital where her blood glucose was found to be 18 mg/dL. ..
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A Case of Minimal Change Disease Treated Successfully with Mycophenolate Mofetil in a Patient with Systemic Lupus Erythematosus
Young Hoon Hong, Dae Young Yun, Yong Wook Jung, Myung Jin Oh, Hyun Je Kim, Choong Ki Lee
Korean J Intern Med. 2011;26(4):470-473. Published online November 28, 2011
The World Health Organization classifies lupus nephritis as class I to V or VI. However, a few cases of minimal change glomerulopathy have been reported in association with systemic lupus erythematosus (SLE). Mycophenolate mofetil has been shown to be effective for treatment of minimal change dis..
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Comparison of Clinical Outcomes by Different Renal Replacement Therapy in Patients with End-Stage Renal Disease Secondary to Lupus Nephritis
Seok-Hui Kang, Byung-Ha Chung, Sun-Ryoung Choi, Ja-Young Lee, Hoon-Suk Park, In-O Sun, Bum-Soon Choi, Cheol-Whee Park, Yong-Soo Kim, Chul-Woo Yang
Korean J Intern Med. 2011;26(1):60-67. Published online March 2, 2011
Background/AimsMany studies have compared patients with systemic lupus erythematosus (SLE) on renal replacement therapy (RRT) with non-lupus patients. However, few data are available on the long-term outcome of patients with end-stage renal disease (ESRD) secondary to SLE who ..
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A Case of Spontaneous Hemoperitoneum Presenting as the Initial Manifestation of Systemic Lupus Erythematosus
Sang-Seokg Seong, Chung-Il Joung
Korean J Intern Med. 2010;25(4):458-460. Published online November 27, 2010
Thrombocytopenia is included in the classification criteria for systemic lupus erythematosus (SLE). However, severe thrombocytopenia causing spontaneous bleeding is rare. Here, we describe a 22-year-old woman who presented with spontaneous hemoperitoneum as the first manifestation of SLE. Laborat..
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A Case of Systemic Lupus Erythematosus Presenting as Malignant Hypertension with Hypertensive Retinopathy
Jung-Yoon Choe, Sung-Hoon Park, Ji-Young Kim, Hyun-Young Jung, Seong-Kyu Kim
Korean J Intern Med. 2010;25(3):341-344. Published online August 31, 2010
The variability of cardiovascular abnormalities is one of the characteristics of systemic lupus erythematosus (SLE). Among the cardiovascular manifestations, hypertension is reported in 14% to 58.1% of patients in diverse ethnic populations, and remains a clinically important issue due to its clo..
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A New Onset of Systemic Lupus Erythematosus Developed After Bee Venom Therapy
Young Hee Rho, Jin-Hyun Woo, Seong Jae Choi, Young Ho Lee, Jong Dae Ji, Gwan Gyu Song
Korean J Intern Med. 2009;24(3):283-285. Published online August 26, 2009
Lupus is a systemic autoimmune disease of an unknown origin, and systemic lupus erythematosus (SLE) can be triggered by numerous stimuli. Bee venom therapy is an alternative therapy that is believed to be effective for various kinds of arthritis. We present here a case of a 49-year-old female who..
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