|
Nephrology / Original Article
Predicting renal function using fundus photography: role of confounders
Hyun-Woong Park, Hae Ri Kim, Ki Yup Nam, Bum Jun Kim, Taeseen Kang
Korean J Intern Med. 2025;40(2):310-320. Published online March 1, 2025
Background/Aims: The kidneys and retina are highly vascularized organs that frequently exhibit shared pathologies, with nephropathy often associated with retinopathy. Previous studies have successfully predicted estimated glomerular filtration rates (eGFRs) using fundus photographs. We evaluated the..
|
|
|
Gastroenterology / Original Article
Characteristics and outcomes of portal vein thrombosis in patients with inflammatory bowel disease in Korea
Ki Jin Kim, Su-Bin Song, Jung-Bin Park, June Hwa Bae, Ji Eun Baek, Ga Hee Kim, Min-Jun Kim, Seung Wook Hong, Sung Wook Hwang, Dong-Hoon Yang, Byong Duk Ye, Jeong-Sik Byeon, Seung-Jae Myung, Suk-Kyun Yang, Chang Sik Yu, Yong-Sik Yoon, Jong-Lyul Lee, Min Hyun Kim, Ho-Su Lee, Sang Hyoung Park
Korean J Intern Med. 2025;40(2):243-250. Published online December 23, 2024
Background/Aims: Portal vein thrombosis (PVT) frequently occurs in patients with inflammatory bowel disease (IBD), particularly when influenced by factors such as abdominal infections, IBD flare-ups, or surgical procedures. The implications of PVT range from immediate issues such as intestinal ische..
|
|
|
Endocrinology-metabolism / Original Article
Fisher discriminant analysis of multimodal ultrasound in diagnosis of cervical metastatic lymph nodes in papillary thyroid cancer
Yixuan Wang, Yue Han, Fei Li, Yuyang Lin, Bei Wang
Korean J Intern Med. 2025;40(1):103-114. Published online October 29, 2024
Background/Aims: The purpose of this study was to develop a diagnostic model utilizing multimodal ultrasound parameters to aid in the detection of cervical lymph node metastasis in papillary thyroid cancer (PTC) patients.
Methods: The study included 84 suspicious lymph nodes from 69 PTC patients, a..
|
|
|
Gastroenterology / Original Article
Tight junction protein changes in irritable bowel syndrome: the relation of age and disease severity
Sang Un Kim, Ji A Choi, Man-Hoon Han, Jin Young Choi, Ji Hye Park, Moon Sik Kim, Yong Hwan Kwon
Korean J Intern Med. 2024;39(6):906-916. Published online November 1, 2024
Background/Aims: The etiology of irritable bowel syndrome (IBS) is associated with intestinal mucosal barrier damage. However, changes in the tight junction (TJ) proteins in IBS have not been fully elucidated. This study aimed to evaluate TJ protein changes in IBS patients and the relationship betwe..
|
|
|
Cardiology / Review
Current evidence for prognostic benefit of intravascular imaging-guided percutaneous coronary intervention in chronic total occlusion intervention
David Hong, Sung Eun Kim, Seung Hun Lee, Seung-Jae Lee, Jong-Young Lee, Sang Min Kim, Sang Yeub Lee, Woochan Kwon, Ki Hong Choi, Taek Kyu Park, Jeong Hoon Yang, Young Bin Song, Seung-Hyuk Choi, Hyeon-Cheol Gwon, Joo-Yong Hahn, Joo Myung Lee; The RENOVATE-COMPLEX-PCI Investigators
Korean J Intern Med. 2024;39(5):702-716. Published online February 29, 2024
Although percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) has been increasing in recent years, CTO PCI is still one of the most challenging procedures with relatively higher rates of procedural complications and adverse clinical events after PCI. Due to the innate limitatio..
|
|
|
Cardiology / Review
Role of cardiac imaging in management of heart failure
So Ree Kim, Seong-Mi Park
Korean J Intern Med. 2023;38(5):607-619. Published online August 29, 2023
The significant advancement in cardiac imaging in recent years led to improved diagnostic accuracy in identifying the specific causes of heart failure and also provided physicians with guidelines for appropriately managing patients with heart failure. Diseases that were once considered rare are now ..
|
|
|
Pulmonology / Original Article
Prognostic outcome of treatment modalities for epidermal growth factor receptor-mutated advanced lung cancer
Seung Hun Jang, Dong Yoon Lee, Jihyeon Jeong, Won-Il Choi
Korean J Intern Med. 2022;37(4):811-820. Published online June 3, 2022
Background/Aims: The treatment of epidermal growth factor receptor (EGFR)-mutated lung cancer cases has shown remarkable development in the past two decades. However, there have been limited studies comparing the prognostic effects of EGFR-tyrosine kinase inhibitor (TKI) and other treatment modaliti..
|
|
|
Gastroenterology / Original Article
Two-dimensional shear wave elastography for assessing liver fibrosis in patients with chronic liver disease: a prospective cohort study
Hae Won Yoo, Sang Gyune Kim, Jae Young Jang, Jeong-Ju Yoo, Soung Won Jeong, Young Seok Kim, Boo Sung Kim
Korean J Intern Med. 2022;37(2):285-293. Published online December 7, 2021
Background/Aims: The objective of this study was to determine whether the newly developed two-dimensional shear wave elastography (2D-SWE, RS85, Samsung-shearwave imaging) was more valid and reliable than transient elastography (TE) for predicting the stage of liver fibrosis.
Methods: The study pro..
|
|
|
Gastroenterology / Original Article
Correlation of the grade of hepatic steatosis between controlled attenuation parameter and ultrasound in patients with fatty liver: a multi-center retrospective cohort study
Jeong-Ju Yoo, Yang Jae Yoo, Woo Ram Moon, Seung Up Kim, Soung Won Jeong, Ha Na Park, Min Gyu Park, Jae Young Jang, Su Yeon Park, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Sang Gyune Kim, Young Seok Kim, Ji Hoon Kim, Jong Eun Yeon, Kwan Soo Byun
Korean J Intern Med. 2020;35(6):1346-1353. Published online November 8, 2019
Background/Aims: The controlled attenuation parameter (CAP), based on transient elastography, is widely used for noninvasive assessment of the degree of hepatic steatosis (HS). We investigated the correlation of the degree HS between CAP and ultrasound (US) in patients with HS.
Methods: In total, 9..
|
|
|
Endocrinology-metabolism / Original Article
Utility of shear wave elastography to detect papillary thyroid carcinoma in thyroid nodules: efficacy of the standard deviation elasticity
Hye Jeong Kim, Mi Kyung Kwak, In Ho Choi, So-Young Jin, Hyeong Kyu Park, Dong Won Byun, Kyoil Suh, Myung Hi Yoo
Korean J Intern Med. 2019;34(4):850-857. Published online February 23, 2018
Background/Aims: The aim of this study was to address the role of the elasticity index as a possible predictive marker for detecting papillary thyroid carcinoma (PTC) and quantitatively assess shear wave elastography (SWE) as a tool for differentiating PTC from benign thyroid nodules.
Methods: One ..
|
|
|
Rheumatology / Original Article
Magnetic resonance imaging-assessed synovial and bone changes in hand and wrist joints of rheumatoid arthritis patients
Kyung-Ann Lee, Sang-Ho Min, Tae-Hyung Kim, Sang-Heon Lee, Hae-Rim Kim
Korean J Intern Med. 2019;34(3):651-659. Published online November 24, 2017
Background/Aims: Magnetic resonance imaging (MRI) is a sensitive and useful method for the detection of synovitis and joint destruction in rheumatoid arthritis (RA) patients. However, the patterns of MRI-detected bone erosion, bone marrow edema (BME), synovitis, and tenosynovitis have received insuf..
|
|
|
Cardiology / Original Article
Experiences of magnetic resonance imaging scanning in patients with pacemakers or implantable cardioverter-defibrillators
Donghoon Han, Si-Hyuck Kang, Youngjin Cho, Il-Young Oh
Korean J Intern Med. 2019;34(1):99-107. Published online April 4, 2018
Background/Aims: Despite the U.S. Food and Drug Adminstration approving a magnetic resonance imaging (MRI)-conditional pacemaker system in 2011, many physicians remain reluctant to perform MRI scanning in patients with cardiac implantable electronic devices. Herein, we aimed to evaluate the real-wor..
|
|
|
Cardiology / Review
Palliative and end-of-life care for heart failure patients in an aging society
Takahiro Okumura, Akinori Sawamura, Toyoaki Murohara
Korean J Intern Med. 2018;33(6):1039-1049. Published online May 23, 2018
The populations of Asian countries are expected to age rapidly in the near future, with a dramatic increase in the number of heart failure (HF) patients also anticipated. The need for palliative and end-of-life care for elderly patients with advanced HF is currently recognized in aging societies. Ho..
|
|
|
Nephrology / Original Article
Caveolin-1 is involved in high glucose accelerated human glomerular mesangial cell senescence
Xin Feng, Wei Gao, Yao Li
Korean J Intern Med. 2017;32(5):883-889. Published online April 6, 2016
Background/Aims: We demonstrated the role of caveolin-1 involved in high glucose (HG)-induced glomerular mesangial cells (GMCs) senescence.
Methods: HG was used to stimulate GMCs. The telomere lengths were analyzed by Southern blot. β-Galactosidase staining was determined. The expressions of caveo..
|
|
|
Endocrinology-metabolism / Review
Sarcopenia and sarcopenic obesity
Kyung Mook Choi
Korean J Intern Med. 2016;31(6):1054-1060. Published online November 1, 2016
Sarcopenia is an age-associated loss of muscle mass and decline in muscle strength; it is common in older adults and is associated with significant morbidity and mortality. Despite its prevalence, there is currently no universally adopted definition of sarcopenia. In addition to low muscle mass meas..
|
|
|
Hemato-oncology / Review
Recent advances in multiple myeloma: a Korean perspective
Junshik Hong, Jae Hoon Lee
Korean J Intern Med. 2016;31(5):820-834. Published online September 1, 2016
Epidemiologically, multiple myeloma (MM) is a malignant disorder of plasma cells with a higher incidence among Western populations than among Asians. However, there is growing evidence of a recent increase in the age-standardized incidence rate (ASR) of MM in Asian countries, particularly Korea. App..
|
|
|
Rheumatology / Original Article
An analysis of age-related loss of skeletal muscle mass and its significance on osteoarthritis in a Korean population
Hun-Tae Kim, Hyun-Je Kim, Hee-Yun Ahn, Young-Hoon Hong
Korean J Intern Med. 2016;31(3):585-593. Published online March 15, 2016
Background/Aims: This study was conducted in order to analyze the effects of sarcopenia on age-related osteoarthritis (OA) of the knee in a Korean population.
Methods: All the Korean subjects who visited the Yeungnam University Medical Center Health Promotion Center between 2008 and 2012 in order t..
|
|
|
Endocrinology-metabolism / Original Article
Comparison of two- and three-dimensional sonography for the prediction of the extrathyroidal extension of papillary thyroid carcinomas
Yang Seon Yi, Sang Soo Kim, Won Jin Kim, Min Jung Bae, Ji Hyun Kang, Bo Gwang Choi, Yun Kyung Jeon, Bo Hyun Kim, Byung Joo Lee, Soo Geun Wang, In Joo Kim, Yong Ki Kim
Korean J Intern Med. 2016;31(2):313-322. Published online December 23, 2015
Background/Aims: The purpose of this study was to compare the diagnostic validity of two-dimensional (2D) and three-dimensional (3D) ultrasonography (US) when predicting the extrathyroidal extension of papillary thyroid cancer.
Methods: All 2D data were interpreted in real time and 3D data were sto..
|
|
|
Cardiology / Original Article
Prediction of infarct severity from triiodothyronine levels in patients with ST-elevation myocardial infarction
Dong Hun Kim, Dong-Hyun Choi, Hyun-Wook Kim, Seo-Won Choi, Bo-Bae Kim, Joong-Wha Chung, Young-Youp Koh, Kyong-Sig Chang, Soon-Pyo Hong
Korean J Intern Med. 2014;29(4):454-465. Published online June 27, 2014
Background/Aims: The aim of the present study was to evaluate the relationship between thyroid hormone levels and infarct severity in patients with ST-elevation myocardial infarction (STEMI).
Methods: We retrospectively reviewed thyroid hormone levels, infarct severity, and the extent of transmura..
|
|
|
Nephrology / Review
The renin-angiotensin system and aging in the kidney
Hye Eun Yoon, Bum Soon Choi
Korean J Intern Med. 2014;29(3):291-295. Published online April 29, 2014
Aging is associated with progressive functional deterioration and structural changes in the kidney. Changes in the activity or responsiveness of the renin-angiotensin system (RAS) occur with aging. RAS changes predispose the elderly to various fluid and electrolyte imbalances as well as acute kidney..
|
|
|
