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Gastroenterology
Efficacy and safety of sofosbuvir–velpatasvir and sofosbuvir–velpatasvir–voxilaprevir for hepatitis C in Korea: a Phase 3b study
Jeong Heo, Yoon Jun Kim, Sung Wook Lee, Youn-Jae Lee, Ki Tae Yoon, Kwan Soo Byun, Yong Jin Jung, Won Young Tak, Sook-Hyang Jeong, Kyung Min Kwon, Vithika Suri, Peiwen Wu, Byoung Kuk Jang, Byung Seok Lee, Ju-Yeon Cho, Jeong Won Jang, Soo Hyun Yang, Seung Woon Paik, Hyung Joon Kim, Jung Hyun Kwon, Neung Hwa Park, Ju Hyun Kim, In Hee Kim, Sang Hoon Ahn, Young-Suk Lim
Korean J Intern Med. 2023;38(4):504-513. Published online June 30, 2023
Background/Aims: Despite the availability of direct-acting antivirals (DAAs) for chronic hepatitis C virus (HCV) infection in Korea, need remains for pangenotypic regimens that can be used in the presence of hepatic impairment, comorbidities, or prior treatment failure. We investigated the efficacy an..
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Changes in the prevalence of hepatitis B and metabolic abnormalities among young men in Korea
Byeong Geun Song, Dong Hyun Sinn, Wonseok Kang, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik
Korean J Intern Med. 2022;37(5):1082-1087. Published online May 13, 2022
Changes in the prevalence of disease over time provide valuable information from a public health perspective. We used data from Korea Military Manpower Administration medical examinations for conscription between 2003 and 2019 (n = 5,355,941), which involved young men aged 19 years, to observe chang..
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Gastroenterology
Potential etiology, prevalence of cirrhosis, and mode of detection among patients with non-B non-C hepatocellular carcinoma in Korea
Jihye Kim, Wonseok Kang, Dong Hyun Sinn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik
Korean J Intern Med. 2020;35(1):65-78. Published online June 17, 2019
Background/Aims: We systematically evaluated the clinical characteristics, prevalence of cirrhosis, and mode of detection in virus-unrelated (non-B non-C, NBNC) hepatocellular carcinoma (HCC) patients in Korea.
Methods: A total of 447 consecutive treatment-naïve NBNC-HCC adult patients who were r..
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Long-term real-world entecavir therapy in treatment-naïve hepatitis B patients: base-line
hepatitis B virus DNA and hepatitis B surface antigen levels predict virologic response
Ju-Yeon Cho, Won Sohn, Dong-Hyun Sinn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Kwang Cheol Koh, Seung Woon Paik, Byung Chul Yoo, Joon Hyeok Lee
Korean J Intern Med. 2017;32(4):636-646. Published online November 4, 2016
Background/Aims: Entecavir is a potent nucleoside analogue with high efficacy and barrier for resistance. We aimed to investigate the long-term efficacy and viral resistance rate of entecavir and explore the factors associated with virologic response, including quantitative hepatitis B surface anti..
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Long-term efficacy of tenofovir disoproxil fumarate therapy after multiple nucleos(t)ide analogue failure in chronic hepatitis B patients
Hyo Jin Kim, Ju-Yeon Cho, Yu Jin Kim, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Kwang Cheol Koh, Seung Woon Paik, Byung Chul Yoo, Joon Hyeok Lee
Korean J Intern Med. 2015;30(1):32-41. Published online December 30, 2014
Background/Aims: The efficacy of tenofovir disoproxil fumarate (TDF) for the treatment of chronic hepatitis B (CHB) patients following prior treatment failure with multiple nucleos(t)ide analogues (NAs) is not well defined, especially in Asian populations. In this study we investigated the efficacy ..
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Assessment of the Efficacy of Reducing Peginterferon Alfa-2a and Ribavirin Dose on Virologic Response in Koreans with Chronic Hepatitis C
Jung Hyun Kwon, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Kwan Soo Byun, Seung Woon Paik, Young Suk Lim, Han Chu Lee, Kwang Hyub Han, Kwan Sik Lee
Korean J Intern Med. 2009;24(3):203-211. Published online August 26, 2009
Background/AimsThe virologic response of Koreans to combination therapy for chronic hepatitis C is similar to westerns; however, dose modification occurs more frequently in Koreans. We evaluated the rates of peginterferon α-2a and ribavirin dose modifications and their effect o..
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Prognostic Significance of Maspin in Pancreatic Ductal Adenocarcinoma
Yun Jeong Lim, Jong Kyun Lee, Woo Young Jang, Sang Yong Song, Kyu Taek Lee, Seung Woon Paik, Jong Chul Rhee
Korean J Intern Med. 2004;19(1):15-18. Published online March 1, 2004
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Prognostic Value of VEGF in Human Pancreatic Ductal Adenocarcinoma
Yun Jeong Lim, Jong Kyun Lee, Cheol Keun Park, Sang Yong Song, Woo Young Jang, Hye Young Ha, Dong Il Park, Kyu Taek Lee, Seung Woon Paik, Byung Chul Yoo, Jong Chul Rhee
Korean J Intern Med. 2004;19(1):10-14. Published online March 1, 2004
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Role of TGF - β1 and TGF - β Type 2 Receptor in Gastric Cancer
Dong Il Park, Hee Jung Son, Sang Yong Song, Won Hyeok Choe, Yun Jeong Lim, Sang Jong Park, Jae J. Kim, Young Ho Kim, Poong Lyul Rhee, Seung Woon Paik, Jong Chul Rhee, Kyoo Wan Choi
Korean J Intern Med. 2002;17(3):160-166. Published online September 1, 2002
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Role of Hyperinsulinemia and Glucose Intolerance in the Pathogenesis of Nonalcoholic Fatty Liver in Patients with Normal Body Weight
Joon Hyoek Lee, Poong Lyul Rhee, Jong Kyun Lee, Kyu Taek Lee, Jae Jun Kim, Kwang Cheol Koh, Seung Woon Paik, Jong Chul Rhee, Kyu Wan Choi
Korean J Intern Med. 1998;13(1):10-14. Published online February 1, 1998
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Hypersenstivity to Acid in Ulcer-Like Functional Dyspepsia
Hee Jung Son, Poong Lyul Rhee, Jae Jun Kim, Kwang Cheol Koh, Seung Woon Paik, Jong Chul Rhee
Korean J Intern Med. 1997;12(2):188-192. Published online June 1, 1997
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The Role of Mucosal Biopsy in the Diagnosis of Chronic Diarrhea: Value of Multiple Biopsies when Colonoscopic Finding is Normal or Nonspecific
Joon Hyoek Lee, Poong Lyul Rhee, Jae Jun Kim, Kwang Chul Koh, Seung Woon Paik, Joung Ho Han, Howe J. Ree, Jong Chul Rhee
Korean J Intern Med. 1997;12(2):182-187. Published online June 1, 1997
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Acute Pancreatitis Complicating Pregnancy in a Patient with Co-Existing Choledochal Cyst
Hee Jung Son, Seung Woon Paik, Poong Lyul Rhee, Jae Jun Kim, Kwang Chul Koh, Jong Chul Rhee
Korean J Intern Med. 1997;12(1):105-108. Published online January 1, 1997
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