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Ahead of Print
> Browse Articles > Ahead of Print
Recent advances in the diagnosis and management of primary myelofibrosis
Katsuto Takenaka, Kazuya Shimoda, Koichi Akashi
Received January 10, 2018 Accepted March 7, 2018 Published online April 20, 2018
DOI:
https://doi.org/10.3904/kjim.2018.033
[Epub ahead of print]
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm (MPN) in which dysregulation of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathways is the major pathogenic mechanism. Most patients with PMF carry a driver mutation in the
JAK2, MPL
(my..
Effect of the anti-IL-17 antibody on allergic inflammation in an obesity-related asthma model
Lin Liang, Jung Hur, Ji Young Kang, Chin Kook Rhee, Young Kyoon Kim, Sook Young Lee
Received June 8, 2017 Accepted September 29, 2017 Published online April 19, 2018
DOI:
https://doi.org/10.3904/kjim.2017.207
[Epub ahead of print]
Background/Aims: The co-occurrence of obesity aggravates asthma symptoms. Diet-induced obesity increases helper T cell (TH) 17 cell differentiation in adipose tissue and the spleen. The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor pravastatin can potentially be used to treat asthma in o..
Review
How to tackle congestion in acute heart failure
Pieter Martens, Wilfried Mullens
Received November 15, 2017 Accepted December 3, 2017 Published online April 11, 2018
DOI:
https://doi.org/10.3904/kjim.2017.355
[Epub ahead of print]
Acute heart failure is a common complication of chronic heart failure and is associated with a high risk for subsequent mortality and morbidity. In 90% of case acute heart failure is the resultant of congestion, a manifestation of fluid build-up due to increased filling pressures. As residual conges..
Experiences of magnetic resonance imaging scanning in patients with pacemakers or implantable cardioverter-defibrillators
Donghoon Han, Si-Hyuck Kang, Youngjin Cho, Il-Young Oh
Received July 19, 2017 Accepted August 23, 2017 Published online April 4, 2018
DOI:
https://doi.org/10.3904/kjim.2017.251
[Epub ahead of print]
Background/Aims: Despite the U.S. Food and Drug Adminstration approving a magnetic resonance imaging (MRI)-conditional pacemaker system in 2011, many physicians remain reluctant to perform MRI scanning in patients with cardiac implantable electronic devices. Herein, we aimed to evaluate the real-wor..
Korean physicians’ policies for postoperative surveillance of colorectal cancer
Sun Kyung Baek, Sang-Cheol Lee, Jong Gwang Kim, Jun Won Um, Suk-Hwan Lee, Byung Ik Jang, Jae Jun Park, Tae Won Kim
Received July 7, 2016 Accepted October 7, 2016 Published online April 4, 2018
DOI:
https://doi.org/10.3904/kjim.2016.215
[Epub ahead of print]
Background/Aims: We explored Korean physicians’ policies for surveillance of colorectal cancer (CRC) after curative surgery. Methods: Web-based self-report questionnaires were developed. Invitations to participate were emailed to physicians who diagnosed and treated CRC from October 1 to Novembe..
Pre-discharge anemia as a predictor of adverse clinical outcomes in patients with acute decompensated heart failure
Min Chul Kim, Kye Hun Kim, Jae Yeong Cho, Ki Hong Lee, Doo Sun Sim, Hyun Ju Yoon, Nam Sik Yoon, Young Joon Hong, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong, Jeong Gwan Cho, Jong Chun Park
Received October 8, 2017 Accepted December 30, 2017 Published online March 23, 2018
DOI:
https://doi.org/10.3904/kjim.2017.337
[Epub ahead of print]
Background/Aims: The impact of the timing of anemia during hospitalization on future clinical outcomes after surviving discharge from an index heart failure (HF) has been poorly studied in patients with acute decompensated heart failure (ADHF). Methods: A total of 384 surviving patients with acute ..
Percutaneous coronary intervention in patients with multi-vessel coronary artery disease: a focus on physiology
Yun-Kyeong Cho, Chang-Wook Nam
Received January 5, 2018 Accepted January 16, 2018 Published online March 21, 2018
DOI:
https://doi.org/10.3904/kjim.2018.006
[Epub ahead of print]
Multi-vessel coronary artery disease (MVD) frequently features ambiguous or intermediate lesions that may be both serial and complex, suggesting that multiple regions require revascularization. Percutaneous coronary intervention (PCI) is associated with various challenges such as appropriate identif..
Treatment patterns of knee osteoarthritis patients in Korea
Ha-Rim Park, Soo-Kyung Cho, Seul Gi Im, Sun-Young Jung, Dalho Kim, Eun Jin Jang, Yoon-Kyoung Sung
Received August 31, 2017 Accepted October 16, 2017 Published online March 21, 2018
DOI:
https://doi.org/10.3904/kjim.2017.304
[Epub ahead of print]
Background/Aims: To evaluate the treatment patterns of knee osteoarthritis (OA) patients in South Korea. Methods: Using the Korean nationwide claims database, all knee OA patients in Korea during 2014 were identified by the knee OA diagnostic code (M17) or any OA diagnostic code (M15 to M19) in com..
Validation of the Friedewald formula for estimating low density lipoprotein cholesterol: the Korea National Health and Nutrition Examination Survey, 2009 to 2011
Jongseok Lee, Sungok Jang, Haemin Jeong, Ohk-Hyun Ryu
Received July 9, 2017 Accepted December 6, 2017 Published online March 21, 2018
DOI:
https://doi.org/10.3904/kjim.2017.233
[Epub ahead of print]
Background/Aims: The aim of this study is to compare Friedewald-estimated and directly measured low density lipoprotein cholesterol (LDL-C) values and assess the concordance in guideline risk classification between the two methods. Methods: The data were derived from the 2009 to 2011 Korea National..
Expanding transcatheter aortic valve replacement into uncharted indications
Guson Kang, Juyong Brian Kim
Received January 9, 2018 Accepted January 31, 2018 Published online March 20, 2018
DOI:
https://doi.org/10.3904/kjim.2018.015
[Epub ahead of print]
Since the first-in-man transcatheter delivery of an aortic valve prosthesis in 2002, the landscape of aortic stenosis therapeutics has shifted dramatically. While initially restricted to non-surgical cases, progressive advances in transcatheter aortic valve replacement and our understanding of its s..
Ezetimibe decreased nonalcoholic fatty liver disease activity score but not hepatic steatosis
Hyo Young Lee, Dae Won Jun, Hyun Jung Kim, Hyunwoo Oh, Waqar Khalid Saeed, Hyeongsik Ahn, Ramsey C. Cheung, Mindie H. Nguyen
Received May 28, 2017 Accepted August 1, 2017 Published online March 20, 2018
DOI:
https://doi.org/10.3904/kjim.2017.194
[Epub ahead of print]
Background/Aims: A number of clinical trials reported varying effects of cholesterol lowering agents in nonalcoholic fatty liver disease (NAFLD) patients. We, therefore, assessed the changes in hepatic steatosis and NAFLD activity score (NAS) after treatment with cholesterol lowering agents in NAFLD..
A score for decision making during percutaneous coronary intervention in acute myocardial infarction patients with multivessel disease
Hae Chang Jeong, Joon Ho Ahn, Min Chul Kim, Doo Sun Sim, Keun Ho Park, Young Joon Hong, Ju Han Kim, Myung Ho Jeong, Ki-Bae Seung, Kiyuk Chang, Youngkeun Ahn
Received April 29, 2017 Accepted September 8, 2017 Published online March 20, 2018
DOI:
https://doi.org/10.3904/kjim.2017.169
[Epub ahead of print]
Background/Aims: The optimal percutaneous coronary intervention (PCI) strategy in patients with acute myocardial infarction (AMI) with multivessel disease (MVD) is uncertain. This study was designed to develop a novel and simple tool for assessing an individualized and optimized PCI strategy in AMI ..
Update of aristolochic acid nephropathy in Korea
Tae Hyun Ban, Ji-Won Min, Changhwan Seo, Da Rae Kim, Yu Ho Lee, Byung Ha Chung, Kyung-Hwan Jeong, Jae Wook Lee, Beom Seok Kim, Sang-Ho Lee, Bum Soon Choi, Jin Suk Han, Chul Woo Yang
Received September 26, 2016 Accepted November 8, 2016 Published online March 20, 2018
DOI:
https://doi.org/10.3904/kjim.2016.288
[Epub ahead of print]
Background/Aims: The true incidence of aristolochic acid nephropathy (AAN) is thought to be underestimated because numerous ingredients known or suspected to contain aristolochic acid (AA) are used in traditional medicine in Korea. Methods: We collected data on cases of AAN since 1996 via a databas..
Paget disease in a radius
Ruiguo Zhang, Guizhi Zhang, Renfei Wang, Qiang Jia, Jian Tan
Received October 2, 2016 Accepted April 2, 2017 Published online March 19, 2018
DOI:
https://doi.org/10.3904/kjim.2016.317
[Epub ahead of print]
Gender difference in the association between brachial-ankle pulse wave velocity and cardiovascular risk scores
Tae-Min Rhee, Hack-Lyoung Kim, Sohee Oh, Woo-Hyun Lim, Jae-Bin Seo, Woo-Young Chung, Sang-Hyun Kim, Myung-A Kim, Joo-Hee Zo
Received October 23, 2017 Accepted December 4, 2017 Published online March 16, 2018
DOI:
https://doi.org/10.3904/kjim.2017.357
[Epub ahead of print]
Background/Aims: Although brachial-ankle pulse wave velocity (baPWV) has been validated as a novel method to predict the cardiovascular risk in general population, the relevance of baPWV to the traditional risk scores has not been clearly revealed. This study investigated the relationship between b..
The effect of metformin on culture conversion in tuberculosis patients with diabetes mellitus
Ye-Jin Lee, Sung Koo Han, Ju Hee Park, Jung Kyu Lee, Deog Keom Kim, Hee Soon Chung, Eun Young Heo
Received July 18, 2017 Accepted October 4, 2017 Published online March 16, 2018
DOI:
https://doi.org/10.3904/kjim.2017.249
[Epub ahead of print]
Background/Aims: Patients with diabetes mellitus (DM) and tuberculosis (TB) have increased morbidity and a high risk of treatment failure or recurrence. It is important to manage both diseases simultaneously. Among anti-diabetic drugs, metformin inhibits intracellular growth of mycobacteria. Therefo..
Clinical activity of fulvestrant in metastatic breast cancer previously treated with endocrine therapy and/or chemotherapy
Mi Hwa Heo, Hee Kyung Kim, Hansang Lee, Ji-Yeon Kim, Jin-Seok Ahn, Young-Hyuck Im, Yeon Hee Park
Received July 4, 2017 Accepted October 27, 2017 Published online March 16, 2018
DOI:
https://doi.org/10.3904/kjim.2017.226
[Epub ahead of print]
Background/Aims: We conducted a retrospective analysis of the clinical activity of fulvestrant in postmenopausal women with hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC) previously treated with endocrine therapy and/or chemotherapy..
Platelet count is associated with sustained virological response rates in treatments for chronic hepatitis C
Baek Gyu Jun, Eui Ju Park, Woong Cheul Lee, Jae Young Jang, Soung Won Jeong, Young Don Kim, Gab Jin Cheon, Young Sin Cho, Sae Hwan Lee, Hong Soo Kim, Yun Nah Lee, Sang Gyune Kim, Young Seok Kim, Boo Sung Kim
Received September 21, 2017 Accepted November 19, 2017 Published online March 14, 2018
DOI:
https://doi.org/10.3904/kjim.2017.322
[Epub ahead of print]
Background/Aims: This study was conducted to clarify the sustained virological response (SVR) prediction ability of baseline and treatment-related factors in patients with chronic hepatitis C virus (HCV) infection. Methods: This retrospective study collected data at four tertiary referral hospitals..
Outcome of donor biliary complications following living donor liver transplantation
Hyun Young Woo, In Seok Lee, Jae Hyuck Chang, Seung Bae Youn, Si Hyun Bae, Jong Young Choi, Ho Jong Chun, Young Kyoung You, Dong Goo Kim, Seung Kew Yoon
Received July 27, 2017 Accepted November 10, 2017 Published online March 14, 2018
DOI:
https://doi.org/10.3904/kjim.2017.264
[Epub ahead of print]
Background/Aims: Biliary complications are the most common donor complication following living donor liver transplantation (LDLT). The aim of this study is to investigate the long-term outcomes of biliary complications in right lobe adult-to-adult LDLT donors, and to evaluate the efficacy of endosco..
Risk factors for hypothyroidism in euthyroid thyroid nodule patients with lymphocytic thyroiditis on fine needle aspiration cytology
Jeong-Min Lee, Jeonghoon Ha, Kwanhoon Jo, Yejee Lim, Min-Hee Kim, Chan-Kwan Jung, So-Lyung Jung, Moo-Il Kang, Bong-Yun Cha, Dong-Jun Lim
Received May 13, 2017 Accepted October 29, 2017 Published online March 13, 2018
DOI:
https://doi.org/10.3904/kjim.2017.177
[Epub ahead of print]
Background/Aims: Lymphocytic thyroiditis as cytology diagnosis from fine needle aspiration (FNA) is frequently detected in patients with thyroid nodules. However, the clinical outcome for upcoming hypothyroid events has been rarely clarified in euthyroid patients. Methods: We retrospectively review..
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