1. It has been previously reported that the age of onset affects the clinical features and course in patients with ulcerative colitis (UC).
2. The Mayo score was higher and there was more frequent extensive UC in young-onset (YO) disease group than there was in the adult-onset (AO) group. There was also more frequent intravenous steroid, infliximab and immunosuppressant use in the YO group than in the AO group. However, there were no differences between YO and AO disease with regard to UC-related admission, operation or oral steroid use.
3. In Korea, compared to that of AO disease, YO UC presented with more advanced clinical features upon diagnosis, and more severe outcomes.
1. The 6.1% of patients who had an episode of acute pulmonary embolism developed chronic thromboembolic pulmonary hypertension (CTEPH) eventually.
2. Initial echocardiographic parameters that assess right ventricular function and morphology could be used as clinical markers for developing CTEPH.
3. Patients with an initial right ventricular systolic pressure above 74.5 mmHg had a higher chance of developing CTEPH.
1. Home blood pressure (HBP) is as good as ambulatory blood pressure (BP) for predicting target organ damage as assessed by echocardiographic left ventricular hypertrophy. Ambulatory BP can be replaced by HBP to manage hypertension (HT) in patients undergoing hemodialysis (HD).
2. Mean pre-post-HD and mean pre-intra-postHD systolic BP should be very useful for managing HT predicting home systolic BP in patients undergoing HD if ambulatory or HBP measurements are unavailable.
3. However, these readings (mean pre-post-HD and mean pre-intra-post-HD systolic BP) should be used with caution with the understanding that they are inferior to ambulatory or HBP measurements.
1. BCR-ABL1 transcripts (MR4.5) at post-transplant 3 months is predictive for relapse in allografted patients with chronic myeloid leukemia.
2. Immune suppressive therapy modulation based on the molecular monitoring is warranted.