| Reviews |
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Gastroenterology
A 2015 roadmap for the management of hepatitis C virus infections in Asia
Seng Gee Lim, Yock Young Dan
Korean J Intern Med. 2015;30(4):423-433. Published online June 29, 2015
The prevalence of hepatitis C virus (HCV) in Asia is 0.5% to 4.7%, with three different genotypes predominating, depending on the geographic region: genotype 1b in East Asia, genotype 3 in South and Southeast Asia, and genotype 6 in Indochina. Official approval for direct-acting antiviral agents (DA..
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Cardiology
Infective endocarditis involving an apparently structurally normal valve: new epidemiological trend?
Jae-Kwan Song
Korean J Intern Med. 2015;30(4):434-442. Published online June 29, 2015
Infective endocarditis (IE) has been increasingly diagnosed in patients without previously detected predisposing heart disease, but its clinical features have yet to be fully determined. A recent single-center study including echocardiographic images and surgical findings investigated the incidence ..
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Pulmonology
Phenotype of asthma-chronic obstructive pulmonary disease overlap syndrome
Chin Kook Rhee
Korean J Intern Med. 2015;30(4):443-449. Published online June 29, 2015
Many patients with asthma or chronic obstructive pulmonary disease (COPD) have overlapping characteristics of both diseases. By spirometric definition, patients with both fixed airflow obstruction (AO) and bronchodilator reversibility or fixed AO and bronchial hyperresponsiveness can be considered t..
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| Editorial |
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Cardiology
Hyponatremia in acute heart failure: a marker of poor condition or a mediator of poor outcome?
Myung Hwan Bae, Shung Chull Chae
Korean J Intern Med. 2015;30(4):450-452. Published online June 29, 2015
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| Original Articles |
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Gastroenterology
Prevalence of and risk factors for endogenous endophthalmitis in patients with pyogenic liver abscesses
In Hyung Park, Chung Hwan Jun, Jin Woo Wi, Seon Young Park, Wan Sik Lee, Sook In Jung, Chang Hwan Park, Young Eun Joo, Hyun Soo Kim, Sung Kyu Choi, Jong Sun Rew
Korean J Intern Med. 2015;30(4):453-459. Published online June 29, 2015
Background/Aims: Although pyogenic liver abscesses (PLAs) can be successfully treated, the visual prognosis of patients with endogenous endophthalmitis (EE) associated with a PLA is poor. Early diagnosis and prompt intervention may salvage useful vision. Therefore, we investigated risk factors for E..
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Cardiology
Prognostic value of hyponatremia in heart failure patients: an analysis of the Clinical Characteristics and Outcomes in the Relation with Serum Sodium Level in Asian Patients Hospitalized for Heart Failure (COAST) study
[editorial]
Byung-Su Yoo, Jin Joo Park, Dong-Ju Choi, Seok-Min Kang, Juey-Jen Hwang, Shing-Jong Lin, Ming-Shien Wen, Jian Zhang, Junbo Ge, on behalf of the COAST investigators
Korean J Intern Med. 2015;30(4):460-470. Published online June 29, 2015
Background/Aims: Hyponatremia is a well-known risk factor for poor outcomes in Western studies of heart failure (HF) patients. We evaluated the predictive value of hyponatremia in hospitalized Asian HF patients.
Methods: The Clinical Characteristics and Outcomes in the Relation with Serum Sodium Le..
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Pulmonology
A combination of early warning score and lactate to predict intensive care unit transfer of inpatients with severe sepsis/septic shock
Jung-Wan Yoo, Ju Ry Lee, Youn Kyung Jung, Sun Hui Choi, Jeong Suk Son, Byung Ju Kang, Tai Sun Park, Jin-Won Huh, Chae-Man Lim, Younsuck Koh, Sang Bum Hong
Korean J Intern Med. 2015;30(4):471-477. Published online June 29, 2015
Background/Aims: The modified early warning score (MEWS) is used to predict patient intensive care unit (ICU) admission and mortality. Lactate (LA) in the blood lactate (BLA) is measured to evaluate disease severity and treatment efficacy in patients with severe sepsis/septic shock. The usefulness o..
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Clinical outcomes of extracorporeal membrane oxygenation support in patients with hematologic malignancies
Hye Seon Kang, Chin Kook Rhee, Hea Yon Lee, Young Kyoon Kim, Soon Seog Kwon, Seok Chan Kim, Jong Wook Lee
Korean J Intern Med. 2015;30(4):478-488. Published online June 29, 2015
Background/Aims: The clinical outcomes of patients with hematologic malignancies who were treated with extracorporeal membrane oxygenation (ECMO) after the failu re of optimal conventional therapy were determined.
Methods: The medical records of all patients administered ECMO during their stay in a..
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Nephrology
Renal Klotho expression in patients with acute kidney injury is associated with the severity of the injury
Min Young Seo, Jihyun Yang, Jun Yong Lee, Kitae Kim, Sun Chul Kim, Hyojeong Chang, Nam Hee Won, Myung-Gyu Kim, Sang-Kyung Jo, Wonyong Cho, Hyoung Kyu Kim
Korean J Intern Med. 2015;30(4):489-495. Published online June 29, 2015
Background/Aims: The potential physiologic roles of Klotho in acute kidney injury (AKI) have recently been demonstrated in animal models. However, to date, there have been no human studies investigating the expression of renal Klotho in AKI.
Methods: We retrospectively collected biopsy specimens a..
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Hemato-oncology
Clinical features and outcomes of systemic amyloidosis with gastrointestinal involvement: a single-center experience
A Young Lim, Ji Hyeon Lee, Ki Sun Jung, Hye Bin Gwag, Do Hee Kim, Seok Jin Kim, Ga Yeon Lee, Jung Sun Kim, Hee-Jin Kim, Soo-Youn Lee, Jung Eun Lee, Eun-Seok Jeon, Kihyun Kim
Korean J Intern Med. 2015;30(4):496-505. Published online June 29, 2015
Background/Aims: The gastrointestinal (GI) tract often becomes involved in patients with systemic amyloidosis. As few GI amyloidosis data have been reported, we describe the clinical features and outcomes of patients with pathologically proven GI amyloidosis.
Methods: We identified 155 patients dia..
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Infectious diseases
Infections after lung transplantation: time of occurrence, sites, and microbiologic etiologies
Ji Hyun Yun, Sang-Oh Lee, Kyung-Wook Jo, Se Hoon Choi, Jina Lee, Eun Jin Chae, Kyung-Hyun Do, Dae-Kee Choi, In-Cheol Choi, Sang-Bum Hong, Tae Sun Shim, Hyeong Ryul Kim, Dong Kwan Kim, Seung-Il Park
Korean J Intern Med. 2015;30(4):506-514. Published online June 29, 2015
Background/Aims: Infections are major causes of both early and late death after lung transplantation (LT). The development of prophylaxis strategies has altered the epidemiology of post-LT infections; however, recent epidemiological data are limited. We evaluated infections after LT at our instituti..
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Drug utilization review of mupirocin ointment in a Korean university-affiliated hospital
Sung Hee Youn, Seung Soon Lee, Sukyeon Kim, Jeong-a Lee, Bum Joon Kim, Jounghee Kim, Hye-kyung Han, Jae-Seok Kim
Korean J Intern Med. 2015;30(4):515-520. Published online June 29, 2015
Background/Aims: Intranasa l mupirocin and chlorhexidine bathing are candidate strategies to prevent healthcare-associated infections caused by methicillin-resistant Staphylococcus aureus (MRSA). In Korea, intranasal mupirocin is not available, and mupirocin ointment, an over-the-counter drug..
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Rheumatology
Allopurinol hypersensitivity syndrome in patients with hematological malignancies: characteristics and clinical outcomes
Hong Ki Min, Boin Lee, Seung-Ki Kwok, Ji Hyeon Ju, Wan-Uk Kim, Young Min Park, Sung-Hwan Park
Korean J Intern Med. 2015;30(4):521-530. Published online June 29, 2015
Background/Aims: Allopurinol is a urate-lowering agent that is commonly used to prevent chemotherapy-related hyperuricemia. Allopurinol hypersensitivity syndrome (AHS) is a disorder involving multiple organs, which may be accompanied by cutaneous adverse reactions. We identified the characteristics ..
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Quantitative analysis of nailfold capillary morphology in patients with fibromyalgia
Dug-Hyun Choi, Hyun-Sook Kim
Korean J Intern Med. 2015;30(4):531-537. Published online June 29, 2015
Background/Aims: Nailfold capillaroscopy (NFC) has been used to examine morphological and functional microcirculation changes in connective tissue diseases. It has been demonstrated that NFC patterns reflect abnormal microvascular dynamics, which may play a role in fibromyalgia (FM) syndrome. The ai..
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| Letters to the editor |
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Gastroenterology
Extramedullary relapse of multiple myeloma presenting as massive upper gastrointestinal bleeding: a rare complication
Bulent Yasar, Pembegul Gunes, Ozgur Guler, Selma Yagcı, Dilek Benek
Korean J Intern Med. 2015;30(4):538-539. Published online June 29, 2015
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Cardiology
Type 2 myocardial infarction after ingestion of mad honey in a patient with normal coronary arteries
Turgut Karabag, Rasit Sayın, Nesimi Yavuz, Ziyaeddin Aktop
Korean J Intern Med. 2015;30(4):540-542. Published online June 29, 2015
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Endocrinology-metabolism
Fatal ischemic stroke in a case of progressive moyamoya vasculopathy associated with uncontrolled thyrotoxicosis
Bon D. Ku, Key-Chung Park, Sung Sang Yoon
Korean J Intern Med. 2015;30(4):543-546. Published online June 29, 2015
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Hemato-oncology
Metastatic sarcomatoid carcinoma presenting as a pedunculated mass on the floor of the mouth
Ki-Bum Won, Jun-Hwa Song, Jeung-Woo Lee, Won-Chul Ha, Keon-Uk Park
Korean J Intern Med. 2015;30(4):547-549. Published online June 29, 2015
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Imatinib mesylate-induced interstitial lung disease in a patient with prior history of Mycobacterium tuberculosis infection
Na-Ri Lee, Ji Won Jang, Hee Sun Kim, Ho-Young Yhim
Korean J Intern Med. 2015;30(4):550-553. Published online June 29, 2015
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| Images of interest |
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Gastroenterology
Hepatic hydatid cyst
[retracted-article]
Keum Nahn Jee
Korean J Intern Med. 2015;30(4):554-555. Published online June 29, 2015
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Endocrinology-metabolism
Importance of careful Tc-MIBI interpretation in patients with thyroid cancer and primary hyperparathyroidism
Kyung Ae Lee, Heung Yong Jin, Hong Sun Baek, Tae Sun Park
Korean J Intern Med. 2015;30(4):556-557. Published online June 29, 2015
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