| Reviews |
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Strategies for successful implementation and permanent maintenance of a rapid response system
Myung Jin Song, Yeon Joo Lee
Korean J Intern Med. 2021;36(5):1031-1039. Published online August 18, 2021
Rapid response systems (RRSs) have been introduced to intervene with patients experiencing non-code medical emergencies and operate widely around the world. An RRS has four components: an afferent limb, an efferent limb, quality improvement, and administration. A proper triggering system, a hospital..
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Improving the care of inflammatory bowel disease (IBD) patients: perspectives and strategies for IBD center management
Jihye Park, Sinyoung Park, Shin Ae Lee, Soo Jung Park, Jae Hee Cheon
Korean J Intern Med. 2021;36(5):1040-1048. Published online August 5, 2021
The incidence and prevalence rates of inf lammatory bowel disease (IBD) have been increasing in East Asian countries over the past few decades. Accordingly, the general understanding and awareness of IBD among healthcare professionals has increased considerably in this region. This increase is ultim..
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Young-onset type 2 diabetes in South Korea: a review of the current status and unmet need
Ye Seul Yang, Kyungdo Han, Tae Seo Sohn, Nam Hoon Kim
Korean J Intern Med. 2021;36(5):1049-1058. Published online September 1, 2021
The prevalence of young-onset (diagnosis at age < 40 years) type 2 diabetes mellitus (T2DM) is increasing globally. Young-onset T2DM has a common pathophysiology of glucose dysregulation as in late-onset T2DM. However, it presents a greater association with obesity and a more rapid decline in β-ce..
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| Editorials |
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Nosocomial exposure to tuberculosis: a snapshot of South Korea
Hayoung Choi
Korean J Intern Med. 2021;36(5):1061-1062. Published online September 1, 2021
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| Original Articles |
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Gastroenterology
Second-look endoscopy findings after endoscopic submucosal dissection for colorectal epithelial neoplasms
Soo-kyung Park, Hyeon Jeong Goong, Bong Min Ko, Haewon Kim, Hyo Sun Seok, Moon Sung Lee
Korean J Intern Med. 2021;36(5):1063-1073. Published online June 9, 2021
Background/Aims: Although second-look endoscopy (SLE) is frequently performed after gastric endoscopic submucosal dissection (ESD) to prevent bleeding, no studies have reported SLE findings after colorectal ESD. This study aimed to investigate SLE findings and their role in preventing delayed bleedi..
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Risk stratification of patients with gastric lesions indefinite for dysplasia
Young Sin Cho, Il-Kwun Chung, Yunho Jung, Su Jung Han, Jae Kook Yang, Tae Hoon Lee, Sang-Heum Park, Sun-Joo Kim
Korean J Intern Med. 2021;36(5):1074-1082. Published online September 9, 2020
Background/Aims: There are no definite guidelines for the management of gastric lesions diagnosed as indefinite for dysplasia (IND) by endoscopic forceps biopsy (EFB). Therefore, this study aimed to evaluate the clinical outcomes of gastric IND and predictive factors for gastric neoplasm.
Methods: ..
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Risk of colorectal cancer in patients with positive results of fecal immunochemical test performed within 5 years since the last colonoscopy
Yoon Suk Jung, Jinhee Lee, Chang Mo Moon
Korean J Intern Med. 2021;36(5):1083-1091. Published online June 18, 2021
Background/Aims: Annual fecal immunochemical tests (FITs) are often repeated within the recommended colonoscopy surveillance intervals. However, it remains unclear whether interval FITs are useful. To answer this question, we assessed the risk of colorectal cancer (CRC) according to the interval fro..
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Impact of liver cirrhosis on the clinical outcomes of patients with COVID-19: a nationwide cohort study of Korea
Dongsub Jeon, Minkook Son, Jonggi Choi
Korean J Intern Med. 2021;36(5):1092-1101. Published online August 18, 2021
Background/Aims: The impact of liver cirrhosis (LC) on the clinical outcomes of patients with coronavirus disease 2019 (COVID-19) remains elusive. This study evaluated the association between LC and the development of severe complications from COVID-19.
Methods: We used the National Health Insuranc..
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Cardiology
Clinical features and predictors of masked uncontrolled hypertension from the Korean Ambulatory Blood Pressure Monitoring Registry
Hyun-Jin Kim, Jeong-Hun Shin, Yonggu Lee, Ju Han Kim, Sun Ho Hwang, Woo Shik Kim, Sungha Park, Sang Jae Rhee, Eun Mi Lee, Sang Hyun Ihm, Wook Bum Pyun, Jinho Shin
Korean J Intern Med. 2021;36(5):1102-1114. Published online June 18, 2021
Background/Aims: The clinical characteristics of patients with masked uncontrolled hypertension (MUCH) have been poorly defined, and few studies have investigated the clinical predictors of MUCH. We investigated the demographic, clinical, and blood pressure (BP) characteristics of patients with MUCH..
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The Korean Hypertension Cohort study: design and baseline characteristics
Hae-Young Lee, Ju-Yeon Lee, Ho-Gyun Shin, Song-Hee Cho, Kyun-Ik Park, Gyu-Chul Oh, Seung-Pyo Lee, Hogon Kim, Hee-Sun Lee, Kwang-Il Kim, Si-Hyuck Kang, Jang Hoon Lee, Se Yong Jang, Ju-Hee Lee, Kye Hun Kim, Jae Yeong Cho, Jae-Hyeong Park, Jieun Jang, Sue K. Park, Jean Kyung Bak
Korean J Intern Med. 2021;36(5):1115-1125. Published online July 22, 2021
Background/Aims: Hypertension (HT) has a significant impact on public health and medical expenses. However, HT is a chronic disease that requires the long-term follow-up of a large number of patients.
Methods: The Korean Hypertension Cohort (KHC) study aimed to develop a model for calculating cardi..
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Prevalence and characteristics of isolated nocturnal hypertension in the general population
Moo-Yong Rhee, Je Sang Kim, Chee Hae Kim, Ji-Hyun Kim, Jung-Ha Lee, Sun-Woong Kim, Deuk-Young Nah, Namyi Gu, Eun-Joo Cho, Ki-Chul Sung, Kyung-Soon Hong
Korean J Intern Med. 2021;36(5):1126-1133. Published online April 5, 2021
Background/Aims: Ascertaining the prevalence of isolated nocturnal hypertension (INHT) in the general population and identifying the characteristics of patients with INHT may be important to determine patients who should receive 24- hour ambulatory blood pressure (BP) measurements. This study aimed ..
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Pulmonology
Estimating the burden of nosocomial exposure to tuberculosis in South Korea, a nationwide population based cross-sectional study
Hyung Woo Kim, Jun-Pyo Myong, Ju Sang Kim
Korean J Intern Med. 2021;36(5):1134-1145. Published online December 18, 2020
Background/Aims: The aim of the study was to investigate the current nationwide burden of nosocomial exposure to tuberculosis (TB) using national health insurance claims data.
Methods: All patients who had claims for drug susceptibility testing for TB from 2012 to 2016, which indicated culture-prov..
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Patterns of medical care utilization according to environmental factors in asthma and chronic obstructive pulmonary disease patients
Eun-Jung Jo, Min-Hyeok Choi, Chang-Hoon Kim, Kyung-Mi Won, Yoo-Keun Kim, Ju-Hee Jeong, Hye Yeon An, Mi-Kyoung Hwang, Hye-Kyung Park
Korean J Intern Med. 2021;36(5):1146-1156. Published online February 10, 2021
Background/Aims: Weather and air pollution are associated with the exacerbation of respiratory diseases. We investigated patterns of medical care use according to meteorological factors and air pollution in patients with asthma or chronic obstructive pulmonary disease (COPD).
Methods: We analyzed t..
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Changes in respiratory virus infection trends during the COVID-19 pandemic in South Korea: the effectiveness of public health measures
Ji Young Park, Hwan Il Kim, Joo-Hee Kim, Sunghoon Park, Yong Il Hwang, Seung Hun Jang, Yong Kyun Kim, Ki-Suck Jung
Korean J Intern Med. 2021;36(5):1157-1168. Published online August 18, 2021
Background/Aims: Studies on the effectiveness of public health measures to prevent respiratory virus transmission in real-world settings are lacking. We investigated the effectiveness of universal mask use and adherence to other personal preventive measures on the changing viral respiratory infectio..
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Nephrology
Reduction in proteinuria after immunosuppressive therapy and long-term kidney outcomes in patients with immunoglobulin A nephropathy
Shin Chan Kang, Hyung Woo Kim, Tae Ik Chang, Ea Wha Kang, Beom Jin Lim, Jung Tak Park, Tae-Hyun Yoo, Hyeon Joo Jeong, Shin-Wook Kang, Seung Hyeok Han
Korean J Intern Med. 2021;36(5):1169-1180. Published online February 10, 2021
Background/Aims: Despite controversy regarding the benefits of immunosuppressive therapy in immunoglobulin A nephropathy (IgAN), clinical outcomes may vary depending on the patient’s responsiveness to this therapy. This study evaluated long-term kidney outcomes according to the extent of proteinur..
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Hemato-oncology
Risk factors for neutropenic fever in non-Hodgkin’s lymphoma patients with primary granulocyte colony-stimulating factor prophylaxis
Yu Ri Kim, Soo-Jeong Kim, Yong Park, Sung Yong Oh, Hwan-Jung Yun, Yeung-Chul Mun, Jin Seok Kim; the Korean Society of Hematology Lymphoma Working Party
Korean J Intern Med. 2021;36(5):1181-1189. Published online July 16, 2021
Background/Aims: Febrile neutropenia (FN) interferes with the proper chemotherapy dose density or intensity in non-Hodgkin’s lymphoma (NHL) patients. Chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) ± rituximab has an intermediate FN risk. Prophylactic granulocy..
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Thrombotic and hemorrhagic events in 2016 World Health Organization-defined Philadelphia-negative myeloproliferative neoplasm
Ik-Chan Song, Sang Hoon Yeon, Myung-Won Lee, Hyewon Ryu, Hyo-Jin Lee, Hwan-Jung Yun, Seon Young Kim, Deog-Yeon Jo
Korean J Intern Med. 2021;36(5):1190-1203. Published online July 22, 2021
Background/Aims: Recent changes in the diagnostic criteria for myeloproliferative neoplasms (MPNs) and increasing patient numbers necessitate updating of the data on vascular events in patients with such disorders.
Methods: In this single-center study, thrombotic and hemorrhagic events were retrosp..
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Infectious diseases
Evaluation of copper alloys for reducing infection by methicillin resistant Staphylococcus aureus and vancomycin resistant Enterococcus faecium in intensive care unit and in vitro
Sung Im Choi, Mee Soo Chang, Taeeun Kim, Kyung Hwa Chung, Seongman Bae, Sung-Han Kim, Chan Jin Yoon, Young Kyoon Kim, Jun Hee Woo
Korean J Intern Med. 2021;36(5):1204-1210. Published online August 18, 2021
Background/Aims: Multi-drug resistant pathogens are increasing among healthcare-associated infections. It is well known that copper and copper alloys have antimicrobial activity. We evaluated the activity of copper against bacteria in a hospital setting in Korea.
Methods: This study was conducted i..
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Rheumatology
The usefulness of trabecular bone score in patients with ankylosing spondylitis
Seoung Wan Nam, Yoon-Kyoung Sung, Dam Kim, Soo-Kyung Cho, Yoonah Song, Yun Young Choi, Yongjin Sim, Tae-Hwan Kim
Korean J Intern Med. 2021;36(5):1211-1220. Published online June 30, 2020
Backgrounds/Aims: This study was performed to reveal the usefulness of the trabecular bone score (TBS) in assessing bone strength in patients with ankylosing spondylitis (AS) in comparison with dual-energy X-ray absorptiometry (DXA) methods.
Methods: A total of 215 AS patients (75.8% male) were enr..
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Evaluation of body composition using computed tomography in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis
Sung Soo Ahn, Byung-Woo Yoo, Hyeok Chan Kwon, Juyoung Yoo, Seung Min Jung, Jason Jungsik Song, Yong-Beom Park, Sang-Won Lee
Korean J Intern Med. 2021;36(5):1221-1232. Published online August 18, 2020
Background/Aims: Measures of body composition, including visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), and skeletal muscle area (SMA), are considered important prognostic factors in chronic diseases. The association of these measures with auto-inflammatory disorders, such as anti..
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Hospital Medicine
Clinical Frailty Scale, K-FRAIL questionnaire, and clinical outcomes in an acute hospitalist unit in Korea
Seung Jun Han, Hee-Won Jung, Jae Hyun Lee, Jin Lim, Sung do Moon, Sock-Won Yoon, Hongran Moon, Seo-Young Lee, Hyeanji Kim, Sae-Rim Lee, Il-Young Jang
Korean J Intern Med. 2021;36(5):1233-1241. Published online June 4, 2021
Background/Aims: Frailty increases the risks of in-hospital adverse events such as delirium, falls, and functional decline in older adults. We assessed the feasibility and clinical relevance of frailty status in Korean older inpatients using the Clinical Frailty Scale (CFS) and Korean version of the..
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Geriatrics
Validity of the Clinical Frailty Scale in Korean older patients at a geriatric clinic
Hee-Won Jung, Il-Young Jang, Ji Yeon Back, Seunghyun Park, Chan MI Park, Seung Jun Han, Eunju Lee
Korean J Intern Med. 2021;36(5):1242-1250. Published online December 30, 2020
Background/Aims: We aimed to assess the validity of the Korean translated version of the Clinical Frailty Scale (CFS) in determining the frailty status in geriatric outpatients.
Methods: The records of 123 ambulatory outpatients who had undergone CFS and comprehensive geriatric assessments (CGAs) i..
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| Images of interest |
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A mass-like lesion encasing the aortic arch and descending aorta: immunoglobulin G4-related periaortitis
Chewan Lim, Chul-Min Ahn, Hyun-Chel Joo, Jung Yoon Pyo, Young-Guk Ko
Korean J Intern Med. 2021;36(5):1256-1257. Published online October 15, 2020
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Distinctive arterial collaterals caused by aortic occlusion in a patient with antiphospholipid syndrome
Shunya Kaneshita, Masei Suda, Masato Okada
Korean J Intern Med. 2021;36(5):1258-1259. Published online June 17, 2020
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| Erratum |
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Effect of omalizumab as add-on therapy to Quality of Life Questionnaire for Korean Asthmatics (KAQLQ) in Korean patients with severe persistent allergic asthma
Jae-Woo Jung, Hae-Sim Park, Choon-Sik Park, Sang-Heon Cho, Inseon S. Choi, Hee-Bom Moon, Soon Seog Kwon, Ho Joo Yoon, Jung Won Park, Jong-Myung Lee, Dong-Chull Choi, Byoung Whui Choi
Korean J Intern Med. 2021;36(5):1260 Published online September 1, 2021
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