| Reviews |
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Cardiology
Pathophysiology and preventive strategies of anthracycline-induced cardiotoxicity
Woo-Baek Chung, Ho-Joong Youn
Korean J Intern Med. 2016;31(4):625-633. Published online July 1, 2016
Cardiotoxicity is a well-known complication following treatment with anthracyclines. However, they are still widely used in chemotherapy for breast cancer, lymphoma, leukemia, and sarcoma, among others. Patient clinical characteristics, such as age, sex, comorbidities, anthracycline dose and infusio..
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Rheumatology
Macrophage migration inhibitory factor: a potential therapeutic target for rheumatoid arthritis
Kyoung-Woon Kim, Hae-Rim Kim
Korean J Intern Med. 2016;31(4):634-642. Published online May 12, 2016
Macrophage migration inhibitory factor (MIF) is originally identified in the culture medium of activated T lymphocytes as a soluble factor that inhibits the random migration of macrophages. MIF is now recognized as a multipotent cytokine involved in the regulation of immune and inf lammatory respons..
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Endocrinology-metabolism
Differences among skeletal muscle mass indices derived from height-, weight-, and body mass index-adjusted models in assessing sarcopenia
Kyoung Min Kim, Hak Chul Jang, Soo Lim
Korean J Intern Med. 2016;31(4):643-650. Published online June 22, 2016
Aging processes are inevitably accompanied by structural and functional changes in vital organs. Skeletal muscle, which accounts for 40% of total body weight, deteriorates quantitatively and qualitatively with aging. Skeletal muscle is known to play diverse crucial physical and metabolic roles in hu..
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| Editorial |
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High prevalence of chronic obstructive pulmonary disease in Korea
Chin Kook Rhee
Korean J Intern Med. 2016;31(4):651-652. Published online July 1, 2016
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| Original Articles |
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Gastroenterology
Is height a risk factor for colorectal adenoma?
Jeung Hui Pyo, Sung Noh Hong, Byung-Hoon Min, Dong Kyung Chang, Hee Jung Son, Poong-Lyul Rhee, Jae J. Kim, Young-Ho Kim
Korean J Intern Med. 2016;31(4):653-659. Published online December 23, 2015
Background/Aims: Although it is generally known that the risk for all types of cancer increases with adult height, combined and for several common site-specific cancers (including colon and rectal), evidence is limited for adenomas, which are precursors to colorectal cancer. We evaluated the associa..
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Clinical efficacy of serum lipase subtype analysis for the differential diagnosis of pancreatic and non-pancreatic lipase elevation
Chang Seok Bang, Jin Bong Kim, Sang Hyun Park, Gwang Ho Baik, Ki Tae Su, Jai Hoon Yoon, Yeon Soo Kim, Dong Joon Kim
Korean J Intern Med. 2016;31(4):660-668. Published online June 1, 2016
Background/Aims: Non-pancreatic elevations of serum lipase have been reported, and differential diagnosis is necessary for clinical practice. This study aimed to evaluate the clinical efficacy of serum lipase subtype analysis for the differential diagnosis of pancreatic and non-pancreatic lipase ele..
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Analysis of risk factor and clinical characteristics of angiodysplasia presenting as upper gastrointestinal bleeding
Dae Bum Kim, Woo Chul Chung, Seok Jong Lee, Hea Jung Sung, Seokyung Woo, Hyo Suk Kim, Yeon Oh Jeong, Hyewon Lee, Yeon-Ji Kim
Korean J Intern Med. 2016;31(4):669-677. Published online January 29, 2016
Background/Aims: Angiodysplasia is important in the differential diagnosis of upper gastrointestinal bleeding (UGIB), but the clinical features and outcomes associated with UGIB from angiodysplasia have not been characterized. We aimed to analyze the clinical characteristics and outcomes of angiodys..
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Cardiology
Five-year clinical outcomes of drug-eluting stents according to on-label and off-label use
Kyu-Hwan Park, Ung Kim, Chan-Hee Lee, Jang-Won Son, Jong-Seon Park, Dong-Gu Shin, Young-Jo Kim, Jeong-Hwan Cho
Korean J Intern Med. 2016;31(4):678-684. Published online March 25, 2016
Background/Aims: To compare the clinical outcomes of ‘on-label’ and ‘off-label’ drug-eluting stents (DESs) over a 5-year follow-up period.
Methods: A total of 929 patients that underwent percutaneous coronary intervention with DESs were enrolled. Patients were divided into two groups according..
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Pulmonology
Smoking habits and nicotine dependence of North Korean male defectors
Sei Won Kim, Jong Min Lee, Woo Ho Ban, Chan Kwon Park, Hyoung Kyu Yoon, Sang Haak Lee
Korean J Intern Med. 2016;31(4):685-693. Published online March 8, 2016
Background/Aims: The smoking rates and patterns in the North Korean population are not well known. More than 20,000 North Korean defectors have settled in South Korea; thus, we can estimate the current North Korean smoking situation using this group.
Methods: All North Korean defectors spend their ..
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Neuron-specific enolase as a novel biomarker reflecting tuberculosis activity and treatment
response
Sung-Jin Nam, Jee-Yeong Jeong, Tae-Won Jang, Mann-Hong Jung, Bong-Kwon Chun, Hee-Jae Cha, Chul-Ho Oak
Korean J Intern Med. 2016;31(4):694-702. Published online June 3, 2016
Background/Aims: It is not clear which tests are indicative of the activity and severity of tuberculosis (TB). This study aimed to investigate the predictive value of neuron-specific enolase (NSE) and to determine the origin of NSE in TB patients.
Methods: A single-center retrospective analysis was..
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Endocrinology-metabolism
Poor glycemic control is associated with the risk of subclinical hypothyroidism in patients with type 2 diabetes mellitus
Jae Ho Cho, Ho Jin Kim, Jun Ho Lee, Il Rae Park, Jun Sung Moon, Ji Sung Yoon, In-Kyu Lee, Kyu Chang Won, Hyoung Woo Lee
Korean J Intern Med. 2016;31(4):703-711. Published online June 8, 2016
Background/Aims: Overt hypothyroidism is frequently found in patients with type 2 diabetes mellitus (T2DM), but it remains unknown the relationship between subclinical hypothyroidism (SCH) and T2DM. We attempt to evaluate the difference in prevalence of SCH between patients with T2DM and general pop..
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Association between household size, residential area, and osteoporosis: analysis of 2008 to 2011 Korea National Health and Nutrition Examination Survey
Sung-Woo Kim, Kwi-Hyun Bae, Jung-Beom Seo, Jae-Han Jeon, Won-Kee Lee, In-Kyu Lee, Jung-Guk Kim, Keun-Gyu Park
Korean J Intern Med. 2016;31(4):712-721. Published online April 15, 2016
Background/Aims: The prevalence of single-person households has rapidly increased in Korea. Individuals living alone and in rural areas may have a higher risk of various metabolic diseases due to differences in lifestyle. However, few studies have investigated the association of household size and r..
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Nephrology
Tumor necrosis factor α is a risk factor for infection in peritoneal dialysis patients
Eunjung Kang, Seihran Kim, Hwa Jung Lee, Inhwee Park, Heungsoo Kim, Gyu-Tae Shin
Korean J Intern Med. 2016;31(4):722-729. Published online March 22, 2016
Background/Aims: It has been shown that circulating tumor necrosis factor α (TNF-α) is elevated in end stage renal disease patients; however, the relationship between TNF-α and the development of infection in these patients is unknown. In this study, we investigated the association of plasma TNF-..
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Liver cirrhosis leads to poorer survival in patients with end-stage renal disease
Ae Jin Kim, Hye Jin Lim, Han Ro, Ji Yong Jung, Hyun Hee Lee, Wookyung Chung, Jae Hyun Chang
Korean J Intern Med. 2016;31(4):730-738. Published online March 26, 2016
Background/Aims: Liver cirrhosis (LC) is an important problem in patients withend-stage renal disease (ESRD). Few studies have investigated the inf luence ofLC on mortality in patients with ESRD. This study investigated the associationbetween LC and mortality among patients with ESRD and compare mor..
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Clinical value of pathologic examination of non-neoplastic kidney in patients with upper urinary tract malignancies
Jee Wan Wee, Hye Ran Kang, Soon Hyo Kwon, Jin Seok Jeon, Dong Cheol Han, So-Young Jin, Won Jae Yang, Hyunjin Noh
Korean J Intern Med. 2016;31(4):739-749. Published online May 30, 2016
Background/Aims: While surgical resection remains the standard of care in the treatment of upper urinary tract malignancies, nephrectomy is a risk factor for the development of chronic kidney disease (CKD). The aim of this study was to determine whether histologic evaluation of non-neoplastic kidney..
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Hemato-oncology
Does anti-thymocyte globulin have a place in busulfan/fludarabine conditioning for matched related donor hematopoietic stem cell transplantation?
Young Sok Ji, Min Sung Lee, Chang Wook Min, Seong Kyu Park, Se Hyung Kim, Jina Yun, Hyun Jung Kim, Kyoung Ha Kim, Chan Kyu Kim, Kyu-Taek Lee, Jong-Ho Won, Dae Sik Hong
Korean J Intern Med. 2016;31(4):750-761. Published online March 28, 2016
Background/Aims: There is controversy about the prophylactic effect of anti-thymocyte globulin (ATG) on graft versus host disease (GVHD) in the setting of matched related-donor hematopoietic stem cell transplantation (HSCT). This study assessed the inf luences of ATG on the incidences of acute and c..
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Infectious diseases
Diagnostic yield of computed tomography-guided bone biopsy and clinical outcomes of tuberculous and pyogenic spondylitis
Eun-Jeong Joo, Joon-Sup Yeom, Young Eun Ha, So Yeon Park, Chong-Suh Lee, Eun-Sang Kim, Cheol-In Kang, Doo-Ryeon Chung, Jae-Hoon Song, Kyong Ran Peck
Korean J Intern Med. 2016;31(4):762-771. Published online April 15, 2016
Background/Aims: This study aimed to evaluate the efficacy of computed tomography (CT)-guided bone biopsy for the diagnosis of spinal infection and compared the clinical outcomes between tuberculous and pyogenic spinal infections.
Methods: The retrospective cohort study included patients who receiv..
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Incidence and risk factors of hepatitis C virus infection among human immunodeficiency virus
(HIV) patients in a large HIV clinic in South Korea
Shinwon Lee, Sun Hee Lee, Su Jin Lee, Kye-Hyung Kim, Jeong Eun Lee, Heerim Cho, Seung Geun Lee, Joo Seop Chung, Ihm Soo Kwak
Korean J Intern Med. 2016;31(4):772-778. Published online April 27, 2016
Background/Aims: Increasing incidences of hepatitis C virus (HCV) infection in human immunodeficiency virus (HIV)-infected men who have sex were reported in the United States and Europe. However, few studies regarding the epidemiology of HCV infection in HIV-infected patients in Asian countries have..
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Rheumatology
Efficacy and safety of low-dose tacrolimus for active rheumatoid arthritis with an inadequate
response to methotrexate
Won-Seok Lee, Sang-Il Lee, Myeung-Soo Lee, Sung-Il Kim, Shin-Seok Lee, Wan-Hee Yoo
Korean J Intern Med. 2016;31(4):779-787. Published online March 10, 2016
Background/Aims: To determine the efficacy and safety of low-dose tacrolimus in Korean rheumatoid arthritis (RA) subjects with an inadequate response to methotrexate (MTX).
Methods: This was a multicenter, open-label study conducted at five Korean sites. Fifty-six patients with active RA, despite t..
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| Letters to the editor |
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The polypoid ganglioneuroma associated with hyperplastic polyposis
Gu Hyum Kang, Byung Seok Lee, Dae Young Kang, Hoon Choi
Korean J Intern Med. 2016;31(4):788-790. Published online December 28, 2015
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Intermittent, subtle change of ST segment in narrow QRS regular tachycardia
Hyeong Won Seo, Hyung Wook Park, Ki Hong Lee, Joon-Ho Ahn, Ji Eun Yu, Nam Sik Yoon, Jeong Gwan Cho
Korean J Intern Med. 2016;31(4):791-793. Published online June 17, 2016
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Ectopic ACTH syndrome caused by pulmonary carcinoid tumor mimicking long-standing sclerosing hemangioma
Sung Yong Han, Bo Hyun Kim, Hee Ryeong Jang, Won Jin Kim, Yun Kyung Jeon, Sang Soo Kim, In Ju Kim
Korean J Intern Med. 2016;31(4):794-797. Published online January 28, 2016
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Urachal abscess precipitated as acute pyelonephritis in an adult patient with diabetes
Yoo A Choi, Se Young Kim, Kyung Yoon Chang, Hyeon Seok Hwang, Suk Young Kim, Yoon Kyung Chang
Korean J Intern Med. 2016;31(4):798-801. Published online January 28, 2016
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A rare case of Rosai-Dorfman disease without lymphadenopathy
Hyerim Ha, Ki Hwan Kim, Young Joon Ahn, Ji Hye Kim, Ji Eun Kim, Sung-Soo Yoon
Korean J Intern Med. 2016;31(4):802-804. Published online February 2, 2016
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| Images of interest |
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Resection of an endobronchial hamartoma by cryotherapy
Hak-Ryul Kim, Keum-Ha Choi, Eun-Taik Jeong, Ki-Eun Hwang
Korean J Intern Med. 2016;31(4):805-806. Published online April 14, 2016
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Angiographically minimal but functionally significant coronary lesion confirmed by optical
coherence tomography
Hyuck-Jun Yoon, Yun-Kyeong Cho, Chang-Wook Nam, Kwon-Bae Kim, Seung-Ho Hur
Korean J Intern Med. 2016;31(4):807-808. Published online June 17, 2016
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