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Nephrology / Original Article
Obesity is associated with incident chronic kidney disease in individuals with normal renal function
Su Hyun Song, Tae Ryom Oh, Sang Heon Suh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim, Eun Hui Bae
Korean J Intern Med. 2024;39(5):813-822. Published online August 13, 2024
Background/Aims: Obesity has known to be a modifiable risk factor associated with worse outcomes in chronic kidney disease (CKD), but few studies have examined the impact of obesity on CKD incidence in the general population. The purpose of this study was to investigate the role of body mass index (..
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Endocrinology-metabolism / Original Article
Patterns of hormonal changes in hypophysitis by immune checkpoint inhibitor
Hyunji Sang, Yun Kyung Cho, Sang-hyeok Go, Hwa Jung Kim, Eun Hee Koh
Korean J Intern Med. 2024;39(5):801-812. Published online August 30, 2024
Background/Aims: Immune checkpoint inhibitors (ICIs) can induce immune-related adverse events, including endocrine dysfunctions, which can have serious consequences on patient health and quality of life. The clinical course and characteristics of immune-related hypophysitis (irH) are not well establ..
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Cardiology / Original Article
Efficacy of single-dose evolocumab injection in early-phase acute myocardial infarction: a retrospective single-center study
Yongcheol Kim, Ji Woong Roh, Oh-Hyun Lee, Seok-Jae Heo, Eui Im, Deok-Kyu Cho, Byeong-Keuk Kim
Korean J Intern Med. 2024;39(5):793-800. Published online June 24, 2024
Background/Aims: Achieving rapid reduction of low-density lipoprotein cholesterol (LDL-C) levels below 55 mg/dL in patients with acute myocardial infarction (AMI) can be challenging with statins alone. This single-center, retrospective study aimed to assess the impact of single-dose injection of evo..
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Gastroenterology / Original Article
Perception of fecal microbiota transplantation in patients with ulcerative colitis in Korea: a KASID multicenter study
Jebyung Park, Sung Noh Hong, Hong Sub Lee, Jongbeom Shin, Eun Hye Oh, Kwangwoo Nam, Gyeol Seong, Hyun Gun Kim, Jin-Oh Kim, Seong Ran Jeon; The Small Intestine Research Group and the Microbiome Research Group of the Korean Association for the Study of Intestinal Diseases (KASID)
Korean J Intern Med. 2024;39(5):783-792. Published online August 30, 2024
Background/Aims: Fecal microbiota transplantation (FMT) is a promising therapy for inducing and maintaining remission in patients with ulcerative colitis (UC). However, FMT has not been approved for UC treatment in Korea. Our study aimed to investigate patient perceptions of FMT under the national m..
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Gastroenterology / Original Article
Prevalence and risk factors for gallstone and renal stone formation in patients with intestinal Behçet’s disease
Jaewon Song, Soo Jung Park, Jae Jun Park, Tae Il Kim, Jihye Park, Jae Hee Cheon
Korean J Intern Med. 2024;39(5):770-782. Published online August 13, 2024
Background/Aims: The association between inflammatory bowel disease (IBD) and gallstone and renal stone formation has been established. However, few studies have investigated this association in patients with intestinal Behçet’s disease (BD). We aimed to examine the prevalence of gallstones and r..
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Gastroenterology / Original Article
Primary surgery versus pharmacotherapy for newly diagnosed ileocecal Crohn’s disease: a hospital-based cohort study
Yehyun Park, Soo Jung Park, Tae Il Kim, Won Ho Kim, Jae Hee Cheon
Korean J Intern Med. 2024;39(5):759-769. Published online June 24, 2024
Background/Aims: Limited knowledge exists regarding the optimal timing and relative advantages of primary surgery compared to medical treatment in ileocecal Crohn’s disease (CD). This study aimed to compare long-term outcomes between medication-based treatment versus surgery in newly diagnosed ile..
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Allergy / Review
Gut microbiota dysbiosis and its impact on asthma and other lung diseases: potential therapeutic approaches
Young-Chan Kim, Kyoung-Hee Sohn, Hye-Ryun Kang
Korean J Intern Med. 2024;39(5):746-758. Published online August 30, 2024
The emerging field of gut-lung axis research has revealed a complex interplay between the gut microbiota and respiratory health, particularly in asthma. This review comprehensively explored the intricate relationship between these two systems, focusing on their influence on immune responses, inflamm..
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Endocrinology-metabolism / Review
Cancer treatment-induced bone loss
Yong Jun Choi
Korean J Intern Med. 2024;39(5):731-745. Published online March 5, 2024
Cancer treatment-induced bone loss (CTBL) is associated with anti-tumor treatments, including endocrine therapies, chemotherapeutic treatments, radiotherapy, glucocorticoids, and tyrosine kinase inhibitors. Osteoporosis, characterized by the loss of bone mass, can increase the risk of fractures, lea..
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Cardiology / Review
2024 KSoLA consensus on secondary dyslipidemia
Hoyoun Won, Jae Hyun Bae, Hyunjung Lim, Minji Kang, Minjoo Kim, Sang-Hak Lee; on behalf of the Clinical Practice Guidelines Committee, Korean Society of Lipid and Atherosclerosis (KSoLA)
Korean J Intern Med. 2024;39(5):717-730. Published online August 30, 2024
Elevated blood cholesterol and triglyceride levels induced by secondary causes are frequently observed. The identification and appropriate handling of these causes are essential for secondary dyslipidemia treatment. Major secondary causes of hypercholesterolemia and hypertriglyceridemia include an u..
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Cardiology / Review
Current evidence for prognostic benefit of intravascular imaging-guided percutaneous coronary intervention in chronic total occlusion intervention
David Hong, Sung Eun Kim, Seung Hun Lee, Seung-Jae Lee, Jong-Young Lee, Sang Min Kim, Sang Yeub Lee, Woochan Kwon, Ki Hong Choi, Taek Kyu Park, Jeong Hoon Yang, Young Bin Song, Seung-Hyuk Choi, Hyeon-Cheol Gwon, Joo-Yong Hahn, Joo Myung Lee; The RENOVATE-COMPLEX-PCI Investigators
Korean J Intern Med. 2024;39(5):702-716. Published online February 29, 2024
Although percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) has been increasing in recent years, CTO PCI is still one of the most challenging procedures with relatively higher rates of procedural complications and adverse clinical events after PCI. Due to the innate limitatio..
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Nephrology / Editorial
Obesity and chronic kidney disease, an important piece in the puzzle of Cardiovascular–Kidney– Metabolic syndrome
Young Youl Hyun
Korean J Intern Med. 2024;39(5):700-701. Published online August 30, 2024
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Gastroenterology / Editorial
Seeking acceptance: how education shifts views on fecal microbiota transplants for ulcerative colitis in Korea
Jeongkuk Seo, Chang Hwan Choi
Korean J Intern Med. 2024;39(5):697-699. Published online August 30, 2024
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Infectious diseases / Image of interest
Bilateral leg pain and swelling with abnormal imaging findings in a patient with voriconazole
Hyeon Mu Jang, Hyeonwoo Kwon, Yunsuk Choi, Sung-Han Kim
Korean J Intern Med. 2024;39(4):695-696. Published online May 27, 2024
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Nephrology / Image of interest
Primary peritoneal carcinoma presented with abdominal pain in patient with kidney transplantation
Eunmi Jo, Sang Heon Song
Korean J Intern Med. 2024;39(4):693-694. Published online April 29, 2024
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Gastroenterology / Image of interest
A rare case of esophageal ulcer: esophageal tuberculosis
Dong-Ge Han, Xiao-Xia Wang, Wei Liu
Korean J Intern Med. 2024;39(4):691-692. Published online April 9, 2024
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Rheumatology / Original Article
Effectiveness of Korean Red Ginseng on fatigue in patients with rheumatic diseases: a randomized, double-blind, placebo-controlled study
Soo-Kyung Cho, Yeo-Jin Song, Jung-Yong Han, Hye Won Kim, Eunwoo Nam, Yoon-Kyoung Sung
Korean J Intern Med. 2024;39(4):680-690. Published online April 5, 2024
Background: To evaluate the effectiveness of Korean Red Ginseng (KRG) in managing fatigue in Korean patients with rheumatic diseases
Methods: Patients were randomly assigned to KRG (2 g/day, n = 60) or placebo (n = 60) groups for 12 weeks of blind phase and then open-label KRG from weeks 12 to 24 (..
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Rheumatology / Original Article
Impact of socioeconomic status on biologics utilization in rheumatoid arthritis: revealing inequalities and healthcare efficiency
Hye Won Kim, Yeon Ju Lee, You-Jung Ha, Eun Bong Lee, Yun Jong Lee, Eun Ha Kang
Korean J Intern Med. 2024;39(4):668-679. Published online February 29, 2024
Background/Aims: This cross-sectional study aimed to investigate biologics treatment disparities in rheumatoid arthritis (RA) patients based on socioeconomic status (SES).
Methods: Data from the KOrean Observational Study Network for Arthritis (KORONA) database were analyzed to assess various facto..
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Allergy / Original Article
Association between specific IgE to staphylococcal enterotoxin B and the eosinophilic phenotype of asthma
Soyoon Sim, Youngwoo Choi, Eun-Mi Yang, Hae-Sim Park
Korean J Intern Med. 2024;39(4):659-667. Published online July 1, 2024
Background/Aims: Sensitization to staphylococcal superantigens (SAgs) could contribute to asthma severity. However, its relevance with eosinophilic phenotype has not yet been clarified. This study aimed to investigate associations between serum specific IgE levels to SAg and eosinophilic airway infl..
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Endocrinology-metabolism / Original Article
Effects of statin use on serum creatinine phosphokinase levels in normal thyroid function
Jeonghoon Ha, Joonyub Lee, Jin Yu, Hakyoung Park, Jiwon Shinn, Seung-Hwan Lee, Jae-Hyoung Cho, Hun-Sung Kim
Korean J Intern Med. 2024;39(4):650-658. Published online June 24, 2024
Background/Aims: Statins are common lipid-lowering agents used in dyslipidemia. However, they increase serum creatinine phosphokinase (CPK) levels. Currently, there are no studies on the effect of thyroid-stimulating hormone (TSH) levels on CPK levels after statin administration. Therefore, this stu..
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Pulmonology / Original Article
Timing and predictors of death during treatment in patients with multidrug/rifampin-resistant tuberculosis in South Korea
Eunjeong Son, Hongjo Choi, Jeongha Mok, Young Ae Kang, Dawoon Jeong, Doosoo Jeon
Korean J Intern Med. 2024;39(4):640-649. Published online June 24, 2024
Background/Aims: This study aimed to investigate the timing and predictors of death during treatment among patients with multidrug/rifampin-resistant tuberculosis (MDR/RR-TB) in South Korea.
Methods: This was a retrospective cohort study that included MDR/RR-TB cases notified between 2011 and 2017 ..
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