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Pulmonology
Relationship between metformin use and mortality in tuberculosis patients with diabetes: a nationwide cohort study
Eunki Chung, Dawoon Jeong, Jeongha Mok, Doosoo Jeon, Hee-Yeon Kang, Heejin Kim, Heesun Kim, Hongjo Choi, Young Ae Kang
Korean J Intern Med. 2024;39(2):306-317. Published online February 6, 2024
Background/Aims: To determine whether metformin, which is considered a host-directed therapy for tuberculosis (TB), is effective in improving the prognosis of patients with TB and diabetes mellitus (DM), who have higher mortality than those without DM.
Methods: This cohort study included patients w..
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Mechanical ventilation in patients with idiopathic pulmonary fibrosis in Korea: a nationwide cohort study
Jae Kyeom Sim, Seok Joo Moon, Juwhan Choi, Jee Youn Oh, Young Seok Lee, Kyung Hoon Min, Gyu Young Hur, Sung Yong Lee, Jae Jeong Shim
Korean J Intern Med. 2024;39(2):295-305. Published online February 8, 2024
Background/Aims: The prognosis of patients with idiopathic pulmonary fibrosis (IPF) and respiratory failure requiring mechanical ventilation is poor. Therefore, mechanical ventilation is not recommended. Recently, outcomes of mechanical ventilation, including those for patients with IPF, have improv..
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Cardiology
Association of epicardial adipose tissue with metabolic risk factors on cardiovascular outcomes: serial coronary computed tomography angiography study
Sungjoon Park, Dong Eun Kim, Su Min Kim, JungMin Choi, Sang Joon Park, Hae-Young Lee, Eun Ju Chun
Korean J Intern Med. 2024;39(2):283-294. Published online February 14, 2024
Background/Aims: Epicardial adipose tissue (EAT) shares pathophysiological properties with other visceral fats and potentially triggers local inflammation. However, the association of EAT with cardiovascular disease (CVD) is still debatable. The study aimed to observe the changes and associations in..
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Metabolic syndrome awareness in the general Korean population: results from a nationwide survey
Hyun-Jin Kim, Mi-Seung Shin, Kyung-Hee Kim, Mi-Hyang Jung, Dong-Hyuk Cho, Ju-Hee Lee, Kwang Kon Koh
Korean J Intern Med. 2024;39(2):272-282. Published online January 30, 2024
Background/Aims: Metabolic syndrome (MetS) raises the risk of cardiovascular disease and type 2 diabetes. An awareness of MetS is vital for early detection and proactive management, which can mitigate the risks associated with MetS. Therefore, our study aimed to investigate the level of awareness of..
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Gastroenterology
Reduced risk of gastrointestinal bleeding associated with eupatilin in aspirin plus acid suppressant users: nationwide population-based study
Hyun Seok Lee, Ji Hyung Nam, Dong Jun Oh, Yeo Rae Moon, Yun Jeong Lim
Korean J Intern Med. 2024;39(2):261-271. Published online December 14, 2023
Background/Aims: Mucoprotective agents, such as eupatilin, are often prescribed to prevent gastrointestinal (GI) bleeding in addition to an acid suppressant despite the absence of a large-scale study. We evaluated the additional effect of eupatilin on the prevention of GI bleeding in both the upper ..
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Model for end-stage liver disease-3.0 vs. model for end-stage liver disease-sodium: mortality prediction in Korea
Jeong Han Kim, Yong Joon Cho, Won Hyeok Choe, So Young Kwon, Byung-Chul Yoo
Korean J Intern Med. 2024;39(2):248-260. Published online February 1, 2024
Background/Aims: The model for end-stage liver disease (MELD) serves as an indicator for short-term mortality among patients diagnosed with liver cirrhosis (LC) and is used to prioritize patients for liver transplantation. In 2021, the updated version of MELD, MELD-3.0, was introduced to improve the..
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Endoscopic mucosal resection using anchored snare Tip-in versus precut technique for small rectal neuroendocrine tumors
Seung Wook Hong, Dong-Hoon Yang, Yoo Jin Lee, Dong Hoon Baek, Jaeyoung Chun, Hyun Gun Kim, Sung Joo Kim, Seung-Mo Hong, Dae-Seong Myung
Korean J Intern Med. 2024;39(2):238-247. Published online December 8, 2023
Background/Aims: Small rectal neuroendocrine tumors (NETs) can be treated with modified endoscopic mucosal resection (EMR). However, an optimal EMR method remains to be established. We aimed to assess the non-inferiority of Tip-in EMR versus precut EMR (EMR-P) for treating rectal NETs.
Methods: Thi..
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The combined use of anti-peptic agents is associated with an increased risk of osteoporotic fracture: a nationwide case-control study
Dong Jun Oh, Ji Hyung Nam, Hyun Seok Lee, Yeo Rae Moon, Yun Jeong Lim
Korean J Intern Med. 2024;39(2):228-237. Published online February 7, 2024
Background/Aims: Long-term use of acid suppressants such as proton pump inhibitors (PPIs) and histamine 2 receptor antagonist (H2RA) has been associated with the risk of osteoporotic fracture. Acid suppressants and muco-protective agents (MPAs) are often used together as anti-ulcer agents. We evalua..
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New targets for type 2-low asthma
Quang Luu Quoc, Youngwoo Choi, Gyu-Young Hur, Hae-Sim Park
Korean J Intern Med. 2024;39(2):215-227. Published online February 6, 2024
Asthma is characterized by airway obstruction and inflammation, and presents significant diagnostic and treatment challenges. The concept of endotypes has improved understanding of the mechanisms of asthma and has stimulated the development of effective treatment strategies. Sputum profiles may be u..
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Nighttime administration of antihypertensive medication: a review of chronotherapy in hypertension
Hyun-Jin Kim, Sang-Ho Jo
Korean J Intern Med. 2024;39(2):205-214. Published online November 16, 2023
Hypertension remains a global health concern because of suboptimal blood pressure control despite advancements in antihypertensive treatments. Chronotherapy, defined as evening or bedtime administration of medication based on biological rhythms, is emerging as a potential strategy to improve blood p..
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Metformin and tuberculosis: extraordinary stories of ordinary co-prevalent patients
Won-Il Choi
Korean J Intern Med. 2024;39(2):203-204. Published online February 28, 2024
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Navigating the risks of using concomitant antipeptic agents in light of osteoporotic concerns
Hae Won Yoo, Su Jin Hong
Korean J Intern Med. 2024;39(2):201-202. Published online February 28, 2024
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Korean treatment recommendations for patients with axial spondyloarthritis
Mi Ryoung Seo, Jina Yeo, Jun Won Park, Yeon-Ah Lee, Ju Ho Lee, Eun Ha Kang, Seon Mi Ji, Seong-Ryul Kwon, Seong-Kyu Kim, Tae-Jong Kim, Tae-Hwan Kim, Hye Won Kim, Min-Chan Park, Kichul Shin, Sang-Hoon Lee, Eun Young Lee, Hoon Suk Cha, Seung Cheol Shim, Youngim Yoon, Seung Ho Lee, Jun Hong Lim, Han Joo Baek; on behalf of the Korean Society of Spondyloarthritis Research
Korean J Intern Med. 2024;39(1):200-200. Published online November 10, 2023
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Intravascular imaging and physiologic assessment in ambiguous coronary lesion
Kyoung-Woo Seo, Jin-Sun Park
Korean J Intern Med. 2024;39(1):198-199. Published online November 10, 2023
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Successful coronary angiography via distal radial access in an 82-year-old male patient with polydactyly
Kang Hee Kim, Bong-Ki Lee, Jeong Hun Seo, Kwang Jin Chun, Byung-Ryul Cho
Korean J Intern Med. 2024;39(1):196-197. Published online September 26, 2023
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Intussusception caused by small bowel metastasis from hepatocellular carcinoma
Young Mi Hong, Jeong Hee Lee, Ki Tae Yoon
Korean J Intern Med. 2024;39(1):194-195. Published online October 5, 2023
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Rheumatology
Characteristics of patients with psoriatic arthritis in Korea: focusing on axial involvement
Hanna Park, Ji Hyun Lee, Seung-Ki Kwok, Ji Hyeon Ju, Wan-Uk Kim, Sung-Hwan Park, Jennifer Jooha Lee
Korean J Intern Med. 2024;39(1):184-193. Published online December 8, 2023
Background/Aims: We aimed to clarify the clinical characteristics of psoriatic arthritis (PsA) in Korean patients focusing on PsA with axial involvement.
Methods: A retrospective medical chart review was performed to identify PsA patients at a single tertiary center. Cases of AS patients with psori..
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Clinical characteristics and prognostic factors of non-tuberculous mycobacterial disease in patients with rheumatoid arthritis
Hyemin Kim, Soyoung Lee, Ji-Won Kim, Ju-Yang Jung, Chang-Hee Suh, Hyoun-Ah Kim
Korean J Intern Med. 2024;39(1):172-183. Published online November 30, 2023
Background/Aims: This study aimed to identify the clinical characteristics of patients with concurrent rheumatoid arthritis (RA) and suspected non-tuberculous mycobacterial (NTM) infections as well as determine their prognostic factors.
Methods: We retrospectively reviewed the medical records of 91..
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Infectious diseases
The effects of remdesivir on mortality and the requirement for mechanical ventilation in patients with COVID-19: a systematic review stratified by disease severity
Seungeun Ryoo, Miyoung Choi, Su-Yeon Yu, Young Kyung Yoon, Kyungmin Huh, Eun-Jeong Joo
Korean J Intern Med. 2024;39(1):160-171. Published online December 28, 2023
Background/Aims: The effectiveness of remdesivir treatment in reducing mortality and the requirement for mechanical ventilation (MV) remains uncertain, as randomized controlled trials (RCTs) have produced conflicting results.
Methods: We searched MEDLINE, EMBASE, Cochrane Central Register of Contro..
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Endocrinology-metabolism
Efficacy and safety of denosumab treatment for Korean patients with Stage 3b–4 chronic kidney disease and osteoporosis
Jin Taek Kim, You Mi Kim, Kyong Yeun Jung, Hoonsung Choi, So Young Lee, Hyo-Jeong Kim
Korean J Intern Med. 2024;39(1):148-159. Published online December 22, 2023
Background/Aims: We evaluated the efficacy and safety of denosumab treatment in severe chronic kidney disease (CKD) patients with osteoporosis. We also investigated whether the treatment affects the coronary artery calcifications.
Methods: Twenty-seven postmenopausal women with Stage 3b–4 CKD and..
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