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Original Article
The Efficacy and Safety of Ezetimibe and Low-Dose Simvastatin as a Primary Treatment for Dyslipidemia in Renal Transplant Recipients
Hye Eun Yoon, Joon Chang Song, Bok Jin Hyoung, Hyeon Seok Hwang, So Young Lee, Youn Joo Jeon, Bum Soon Choi, Yong Soo Kim, Chul Woo Yang
Korean J Intern Med. 2009;24(3):233-237. Published online August 26, 2009
Background/AimsThe efficacy and safety of a combination of ezetimibe and low-dose statin as primary treatment for dyslipidemia in renal transplant patients were evaluated prospectively. MethodsThe study enrolled 77 renal transplant recipients wi..
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Original Article
Endoscopic and Histopathologic Predictors of Recurrence of Colorectal Adenoma on Lowering the Miss Rate
Jeong-Seon Ji, Kyu-Yong Choi, Won-Chul Lee, Bo-In Lee, Soo-Heon Park, Hwang Choi, Byung-Wook Kim, Hiun-Suk Chae, Yong-Moon Park, Young-Jun Park
Korean J Intern Med. 2009;24(3):196-202. Published online August 26, 2009
Background/AimsAlthough colorectal adenoma is reported to recur frequently, this may result from missing it at baseline. However, few studies of recurrence have considered the miss rate. This study evaluated the recurrence rate prospectively and clinical predictors of recurren..
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Case Report
Acute Fibrinous and Organizing Pneumonia Following Hematopoietic Stem Cell Transplantation
Sang Min Lee, Jae-Jung Park, Sun Hee Sung, Yookyung Kim, Kyoung Eun Lee, Yeung-Chul Mun, Soon Nam Lee, Chu Myong Seong
Korean J Intern Med. 2009;24(2):156-159. Published online June 8, 2009
A 60-year-old man presented with cough, sputum, and dyspnea. He had a history of acute myeloid leukemia and hematopoietic stem cell transplantation with chronic renal failure. Chest CT scans showed miliary nodules and patchy consolidations. Histological examination revealed numerous fibrin balls ..
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Case Report
Acute Embolic Occlusion of the Left Common Iliac Artery Treated With Intra-Arterial Thrombolysis and Percutaneous Thrombectomy
Wang-Soo Lee, Kwang Je Lee, Wang Seong Ryu
Korean J Intern Med. 2009;24(2):153-155. Published online June 8, 2009
Acute embolic occlusion of the common iliac artery is a rare medical emergency that is not only limb-threatening, but also potentially life-threatening. Several treatment options exist for acute limb ischemia, although no treatment is clearly best. We report a case of acute embolic occlusion of t..
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Original Article
Effect of the Combined Use of Tramadol and Milnacipran on Pain Threshold in an Animal Model of Fibromyalgia
Seong-Ho Kim, Junhwa Song, Hyunil Mun, Keon Uk Park
Korean J Intern Med. 2009;24(2):139-142. Published online June 8, 2009
Background/AimsAcidic saline injections produce mechanical hyperresponsiveness in male Sprague-Dawley rats. We investigated the effect of milnacipran in conjunction with tramadol on the pain threshold in an acidic saline animal model of pain. Methods
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Original Article
Diagnosis and Species Identification of Mycobacterial Infections by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism Analysis of Sterile Body Fluids
Cheong Ho Cho, Sang Hoon Han, Bum Sik Chin, Suk Hoon Choi, Han Sung Lee, Chang Oh Kim, Myung Soo Kim, Jun Yong Choi, Young Goo Song, June Myung Kim
Korean J Intern Med. 2009;24(2):135-138. Published online June 8, 2009
Background/AimsThe development of effective, accurate, and rapid diagnostic methods for Mycobacterium infection and mycobacterial species identification is required. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) is an easy, rapi..
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Original Article
Clinicopathologic Characteristics of T-cell Non-Hodgkin's Lymphoma: A Single Institution Experience
Ock Bae Ko, Dae Ho Lee, Sang We Kim, Jung Shin Lee, Shin Kim, Jooryung Huh, Cheolwon Suh
Korean J Intern Med. 2009;24(2):128-134. Published online June 8, 2009
Background/AimsAlthough the incidence of T-cell non-Hodgkin's lymphoma (NHL) is higher in Far East Asia than in Western countries, its incidence and clinical course in Korea are not well-defined. Therefore, we assessed the relative frequency and clinical features of T-cell NHL..
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Original Article
Cilostazol Protects Endothelial Cells Against Lipopolysaccharide-Induced Apoptosis Through ERK1/2- and P38 MAPK-Dependent Pathways
Jong-Hoon Lim, Jae-Suk Woo, Yung-Woo Shin
Korean J Intern Med. 2009;24(2):113-122. Published online June 8, 2009
Background/AimsWe examined the effects of cilostazol on mitogen-activated protein kinase (MAPK) activity and its relationship with cilostazol-mediated protection against apoptosis in lipopolysaccharide (LPS)-treated endothelial cells. MethodsHum..
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Original Article
Diagnostic Yield of Tissue Sampling Using a Bite-On-Bite Technique for Incidental Subepithelial Lesions
Jeong-Seon Ji, Bo-In Lee, Kyu-Yong Choi, Byung-Wook Kim, Hwang Choi, Min Huh, Woo-Chul Chung, Hiun-Suk Chae, In-Sik Chung
Korean J Intern Med. 2009;24(2):101-105. Published online June 8, 2009
Background/AimsTechniques for endoscopic evaluation of gastrointestinal subepithelial lesions include conventional endoscopy, jumbo biopsy, endoscopic ultrasonogrphy (EUS), EUS-guided fine needle aspiration, and endoscopic submucosal resection. However, these procedures have m..
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Original Article
Marked Recovery From Paraquat-Induced Lung Injury During Long-Term Follow-up
Kwon-Hyun Lee, Hyo-Wook GIL, Young-Tong Kim, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2009;24(2):95-100. Published online June 8, 2009
Background/AimsParaquat-induced lung injury has been considered a progressive and irreversible disease. The purpose of this study was to report the long-term evolution of lung lesions in eight survivors with significant paraquat-induced lung injuries who could be followed-up f..
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Case Report
Long-Term Survival in a Patient With Ruptured Hepatocellular Carcinoma
Joon Sung Kim, Seung Kew Yoon, Jeong Ah Kim, Chang Wook Kim, Si Hyun Bae, Jong Young Choi, Chan-Kwon Jung
Korean J Intern Med. 2009;24(1):63-67. Published online March 6, 2009
A 57-yr-old woman previously diagnosed with chronic hepatitis B was admitted via the emergency room because she suddenly developed epigastric pain with abdominal distension. On computed tomography (CT), a round enhancing mass was found on the left hepatic lobe with ascites in the peritoneal space..
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Original Article
The Effect of Residual Renal Function at the Initiation of Dialysis on Patient Survival
Seoung Gu Kim, Nam Ho Kim
Korean J Intern Med. 2009;24(1):55-62. Published online March 6, 2009
Background/AimsThe optimal time point for initiating renal replacement therapy in patients with end-stage renal disease remains controversial. The primary objective of our study was to determine the effects of residual renal function at the beginning of renal replacement thera..
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Original Article
EGFR and KRAS Mutations in Patients With Adenocarcinoma of the Lung
Tae Won Jang, Chul Ho Oak, Hee Kyung Chang, Soon Jung Suo, Mann Hong Jung
Korean J Intern Med. 2009;24(1):48-54. Published online March 6, 2009
Background/AimsMutations of the epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS) are important in the pathogenesis of lung cancer, and recent reports have revealed racial and geographical differences in mutation expression.
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Original Article
A Comparison of Patient Acceptance and Preferences Between CT Colonography and Conventional Colonoscopy in Colorectal Cancer Screening
Hyuk Sang Jung, Dong Kyun Park, Min Ju Kim, Sang Kyun Yu, Kwang An Kwon, Yang Suh Ku, Yu Kyung Kim, Ju Hyun Kim
Korean J Intern Med. 2009;24(1):43-47. Published online March 6, 2009
Background/AimsColorectal cancer, one of the most common cancers in developed countries, is curable when diagnosed at an early stage. However, for better screening, both a test that patients will tolerate and diagnostic accuracy are required. We compared patient experiences an..
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Original Article
Gemcitabine, Etoposide, Cisplatin, and Dexamethasone in Patients With Refractory or Relapsed Non-Hodgkin's Lymphoma
Ki-Hyang Kim, Young-Don Joo, Chang-Hak Sohn, Ho-Jin Shin, Joo-Seop Chung, Goon-Jae Cho, Sung-Hoon Shin, Yang-Soo Kim, Won-Sik Lee
Korean J Intern Med. 2009;24(1):37-42. Published online March 6, 2009
Background/AimsTo date, an effective salvage chemotherapy regimen for the treatment of refractory or relapsing non-Hodgkin's lymphoma (NHL) has not been discovered. This study was conducted to evaluate the efficacy and safety of gemcitabine, etoposide, cisplatin, and dexametha..
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Original Article
Relationship Between Left Atrial Size and Stroke in Patients With Sinus Rhythm and Preserved Systolic Function
Bong Soo Kim, Hyun Jik Lee, Jae Hoon Kim, Hee Sang Jang, Byung Seok Bae, Hyun Jae Kang, Bong Ryeol Lee, Byung Chun Jung
Korean J Intern Med. 2009;24(1):24-32. Published online March 6, 2009
Background/AimsIncreased left atrial (LA) size has been proposed as a predictor of poor cardiovascular outcome in the elderly. In the present study, we evaluated the relationship between LA size and stroke in subjects of all ages who presented with preserved left ventricular s..
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Review
Overview of Therapeutic Drug Monitoring
Ju-Seop Kang, Min-Ho Lee
Korean J Intern Med. 2009;24(1):1-10. Published online March 6, 2009
Therapeutic drug monitoring (TDM) is the clinical practice of measuring specific drugs at designated intervals to maintain a constant concentration in a patient's bloodstream, thereby optimizing individual dosage regimens. It is unnecessary to employ TDM for the majority of medications, and it is..
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Case Report
A case of blue rubber bleb nevus syndrome
Seung-Hwan Shin, Hiun-Suk Chae, Jeong-Seon Ji, Hyung-Keun Kim, Young-Seok Cho, Eun-Deok Chang, Kyu-Yong Choi
Korean J Intern Med. 2008;23(4):208-212. Published online December 30, 2008
Blue rubber bleb nevus syndrome is a rare disorder that is characterized by multiple recurrent vascular malformations, such as hemangioma, and these primarily involve the skin and the gastrointestinal tract. It may also involve the brain, liver, lungs, and skeletal muscles. A 14-year-old female v..
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Original Article
Relationship between serum brain natriuretic peptide and heart function in patients with chronic kidney disease
Jae Won Yang, Min Soo Kim, Jae Seok Kim, Jong Myoung Yoo, Seung Tae Han, Bi Ro Kim, Yun Deok Kim, Jeong Wook Choi, Seung Ok Choi, Byoung Geun Han
Korean J Intern Med. 2008;23(4):191-200. Published online December 30, 2008
Background/AimsBrain natriuretic peptide (BNP) levels are known to be elevated in patients with chronic kidney disease (CKD) and normal heart function. Therefore, the present study was performed to examine the effectiveness of BNP level in diagnosing heart failure in patients ..
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Original Article
Autologous stem cell transplantation for diffuse large B-cell lymphoma with residual extranodal involvement
Ock Bae Ko, Geundoo Jang, Shin Kim, Jooryung Huh, Cheolwon Suh
Korean J Intern Med. 2008;23(4):182-190. Published online December 29, 2008
Background/AimsDiffuse large B-cell lymphoma (DLBCL) in Koreans is frequently accompanied by extranodal (EN) disease at the time of autologous stem cell transplantation (ASCT). We sought to determine whether high EN involvement affected survival following ASCT in Koreans. <..
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