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Pulmonary graft-versus-host disease after autologous hematopoietic stem cell transplantation
Sue In Choi, Eun Joo Lee, Dong Oh Kang, Sang Yeub Lee, Kwang Ho In, Han-Kyeom Kim, Sanghoon Park
Korean J Intern Med. 2016;31(6):1181-1183. Published online December 23, 2015
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A confusing case of multiple sclerosis and central nervous system graft versus host disease
Byung-Nam Yoon, Choong Kun Ha, Kwang-Woo Lee, Sung-Hye Park, Jung-Joon Sung
Korean J Intern Med. 2016;31(5):995-998. Published online February 3, 2016
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Infectious diseases
Differences of cytomegalovirus diseases between kidney and hematopoietic stem cell transplant recipients during preemptive therapy
Tark Kim, Yu-Mi Lee, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Heungsup Sung, Joo Hee Jung, Sung Shin, Young Hoon Kim, Young-Ah Kang, Young-Shin Lee, Jung-Hee Lee, Je-Hwan Lee, Kyoo-Hyung Lee, Su-Kil Park, Duck Jong Han, Sung-Han Kim
Korean J Intern Med. 2016;31(5):961-970. Published online April 8, 2016
Background/Aims: Cytomegalovirus (CMV) surveillance and preemptive therapy is a widely-used strategy for preventing CMV disease in transplant recipients. However, there are limited data on the incidence and patterns of CMV disease during the preemptive period. Thus, we investigated the incidence and..
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Hemato-oncology
Does anti-thymocyte globulin have a place in busulfan/fludarabine conditioning for matched related donor hematopoietic stem cell transplantation?
Young Sok Ji, Min Sung Lee, Chang Wook Min, Seong Kyu Park, Se Hyung Kim, Jina Yun, Hyun Jung Kim, Kyoung Ha Kim, Chan Kyu Kim, Kyu-Taek Lee, Jong-Ho Won, Dae Sik Hong
Korean J Intern Med. 2016;31(4):750-761. Published online March 28, 2016
Background/Aims: There is controversy about the prophylactic effect of anti-thymocyte globulin (ATG) on graft versus host disease (GVHD) in the setting of matched related-donor hematopoietic stem cell transplantation (HSCT). This study assessed the inf luences of ATG on the incidences of acute and c..
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Nephrology
Safety and immunologic benefits of conversion to sirolimus in kidney transplant recipients with long-term exposure to calcineurin inhibitors
Ji Hyun Yu, Kyoung Woon Kim, Bo-Mi Kim, Byung Ha Chung, Mi-La Cho, Bum Soon Choi, Cheol Whee Park, Yong-Soo Kim, Chul Woo Yang
Korean J Intern Med. 2016;31(3):552-559. Published online March 11, 2016
Background/Aims: Sirolimus (SRL) is a promising immunosuppressant replacingcalcineurin inhibitors (CNIs). This study was performed to evaluate the safetyand immunologic benefits of conversion to SRL in stable kidney transplant (KT)recipients exposed to CNIs for long periods.
Methods: Fourteen CNI-t..
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Risk factors in the progression of BK virus-associated nephropathy in renal transplant recipients
Hae Min Lee, In-Ae Jang, Dongjae Lee, Eun Jin Kang, Bum Soon Choi, Cheol Whee Park, Yeong Jin Choi, Chul Woo Yang, Yong-Soo Kim, Byung Ha Chung
Korean J Intern Med. 2015;30(6):865-872. Published online October 30, 2015
Background/Aims: BK virus-associated nephropathy (BKVAN) is an important cause of allograft dysfunction in kidney transplant recipients. It has an unfavorable clinical course, and no definite treatment guidelines have yet been established. Here, we report our center’s experience with biopsy-proven ..
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Role of dipeptidyl peptidase-4 inhibitors in new-onset diabetes after transplantation
Sun Woo Lim, Ji Zhe Jin, Long Jin, Jian Jin, Can Li
Korean J Intern Med. 2015;30(6):759-770. Published online October 30, 2015
Despite strict pre- and post-transplantation screening, the incidence of new-onset diabetes after transplantation (NODAT) remains as high as 60%. This complication affects the risk of cardiovascular events and patient and graft survival rates. Thus, reducing the impact of NODAT could improve overall..
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Limited immune tolerance induced by transient mixed chimerism
Ji Hyun Yu, Byung Ha Chung, Eun Ji Oh, Ji-Il Kim, Hee-Je Kim, In Sung Moon, Chul Woo Yang
Korean J Intern Med. 2015;30(5):735-738. Published online August 27, 2015
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Infectious diseases
Clinical significance of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci colonization in liver transplant recipients
Youn Jeong Kim, Sang Il Kim, Jong Young Choi, Seung Kyu Yoon, Young-Kyoung You, Dong Goo Kim
Korean J Intern Med. 2015;30(5):694-704. Published online August 27, 2015
Background/Aims: Liver transplant patients are at high risk for methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) colonization. We evaluated patients before and after liver transplant using active surveillance culture (ASC) to assess the prevalence ..
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Nephrology
Immunologic and non-immunologic complications of a third kidney transplantation
Hyun Seon Kim, Jae Young Kim, Eun Jin Kang, Yoon Seok Choi, Ji-Il Kim, In Sung Moon, Bum Soon Choi, Cheol Whee Park, Chul Woo Yang, Yong-Soo Kim, Byung Ha Chung
Korean J Intern Med. 2015;30(5):657-664. Published online August 27, 2015
Background/Aims: Patients who undergo repeat kidney transplantations (KTs) are considered at high risk for experiencing immunologic and non-immunologic complications. In this study, we investigated the clinical outcomes, including medical and surgical complications, of patients who underwent a third..
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Infectious diseases
Infections after lung transplantation: time of occurrence, sites, and microbiologic etiologies
Ji Hyun Yun, Sang-Oh Lee, Kyung-Wook Jo, Se Hoon Choi, Jina Lee, Eun Jin Chae, Kyung-Hyun Do, Dae-Kee Choi, In-Cheol Choi, Sang-Bum Hong, Tae Sun Shim, Hyeong Ryul Kim, Dong Kwan Kim, Seung-Il Park
Korean J Intern Med. 2015;30(4):506-514. Published online June 29, 2015
Background/Aims: Infections are major causes of both early and late death after lung transplantation (LT). The development of prophylaxis strategies has altered the epidemiology of post-LT infections; however, recent epidemiological data are limited. We evaluated infections after LT at our instituti..
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Hemato-oncology
Role of frontline autologous stem cell transplantation in young, high-risk diffuse large B-cell lymphoma patients
Jae-Ho Yoon, Jong-Wook Kim, Young-Woo Jeon, Sung-Eun Lee, Ki-Seong Eom, Yoo-Jin Kim, Seok Lee, Hee-Je Kim, Chang-Ki Min, Jong-Wook Lee, Woo-Sung Min, Chong-Won Park, Seok-Goo Cho
Korean J Intern Med. 2015;30(3):362-371. Published online April 29, 2015
Background/Aims: Several studies have demonstrated the effect of autologous hematopoietic stem cell transplantation (auto-HSCT) as a salvage treatment for patients with relapsed diffuse large B-cell lymphoma (DLBCL). However, the role of auto-HSCT as a frontline treatment has not been fully investig..
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Recent advances in treatment of aplastic anemia
Seung Hwan Shin, Sung Eun Lee, Jong Wook Lee
Korean J Intern Med. 2014;29(6):713-726. Published online October 31, 2014
Recent advances in the treatment of aplastic anemia (AA) made most of patients to expect to achieve a long-term survival. Allogeneic stem cell transplantation (SCT) from HLA-matched sibling donor (MSD-SCT) is a preferred first-line treatment option for younger patients with severe or very severe AA,..
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Etanercept for steroid-refractory acute graft versus host disease following allogeneic hematopoietic stem cell transplantation
Joo Han Park, Hyo Jung Lee, Sei Rhan Kim, Ga Won Song, Seung Kyong Lee, Sun Young Park, Ki Chan Kim, Sun Hyuk Hwang, Joon Seong Park
Korean J Intern Med. 2014;29(5):630-636. Published online August 28, 2014
Background/Aims: The treatment for steroid-refractory acute graft versus host disease (GVHD) after allogeneic stem cell transplantation (allo-SCT) needs to be standardized. We report our clinical experience with etanercept for steroid-refractory acute GVHD.
Methods: Eighteen patients who underwent ..
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Recurrent neutropenia induced by rifabutin in a renal transplant recipient
Ji Yeun Chang, Eun Gyo Jeong, Ji Hyun Yu, Byung Ha Chung, Chul Woo Yang
Korean J Intern Med. 2014;29(4):532-534. Published online June 27, 2014
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Nephrology
Effects of pretransplant plasmapheresis and rituximab on recurrence of focal segmental glomerulosclerosis in adult renal transplant recipients
Hoon Suk Park, Yuah Hong, In O Sun, Byung Ha Chung, Hyung Wook Kim, Bum Soon Choi, Cheol Whee Park, Dong Chan Jin, Yong Soo Kim, Chul Woo Yang
Korean J Intern Med. 2014;29(4):482-488. Published online June 27, 2014
Background/Aims: Recurrent focal segmental glomerulosclerosis (FSGS) following renal transplantation is relatively common. However, the risk factors and optimal pretransplant treatment preventing recurrence of FSGS remain controversial.
Methods: We retrospectively reviewed 27 adult renal transplan..
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Successful treatment of myelodysplastic
syndrome and Behcet colitis after allogeneic
hematopoietic stem cell transplantation
Min-Ha Kook, Ho-Young Yhim, Na-Ri Lee, Eun-Kee Song, Hee Sun Kim, Chang-Yeol Yim, Jae-Yong Kwak
Korean J Intern Med. 2014;29(1):123-125. Published online January 2, 2014
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Microbiology
Counteracting the enzymatic activity of dipeptidylpeptidase 4 for potential therapeutic advantage, with an emphasis on cord blood transplantation
Hal E. Broxmeyer
Korean J Intern Med. 2013;28(6):639-645. Published online October 29, 2013
Dipeptidylpeptidase (DPP) 4, also known as CD26, is an enzyme present on the surface of a number of different cell types. It is also found within cells and as a soluble protein in body fluids. It can specifically truncate proteins at the penultimate N-terminus residue for some amino acids, such a..
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Nephrology
Clinical characteristics and outcomes in renal transplant recipients with renal cell carcinoma in the native kidney
In O Sun, Yu Mi Ko, Eun Young Kim, Kyung Seon Park, Hong Soon Jung, Sun Hye Ko, Byung Ha Chung, Bum Soon Choi, Cheol Whee Park, Yong Soo Kim, Chul Woo Yang
Korean J Intern Med. 2013;28(3):347-351. Published online May 1, 2013
Background/AimsWe investigated the incidence and clinical characteristics of renal cell carcinoma (RCC) in the native kidney of renal transplant recipients. MethodsBetween 1991 and 2010, 1,425 patients underwent kidney transplantation at our ins..
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Cytomegalovirus Induced Interstitial Nephritis and Ureteral Stenosis in Renal Transplant Recipient
Sung Ha Bae, Byung Ha Chung, Yun Kyung Park, Kwanhoon Jo, Chul Woo Yang, Yong-Soo Kim, Bum Soon Choi
Korean J Intern Med. 2012;27(4):470-473. Published online November 27, 2012
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