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Rheumatology / Original Article
Autonomic dysfunction in primary Sjogren’s syndrome: a prospective cohort analysis of 154 Korean patients
Jung Hee Koh, Seung-Ki Kwok, Jennifer Lee, Sung-Hwan Park
Korean J Intern Med. 2017;32(1):165-173. Published online March 25, 2016
Background/Aims: To determine the prevalence of autonomic dysfunction among Korean patients with primary Sjogren’s syndrome (pSS) and its associations with the clinical features of pSS. Methods: We analyzed 154 participants from the Korean Initiative of primary Sjogren’s Syndrome (KISS) as a pros..
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Cardiology / Original Article
Impact of the β-1 adrenergic receptor polymorphism on tolerability and efficacy of bisoprolol therapy in Korean heart failure patients: association between β adrenergic receptor polymorphism and bisoprolol therapy in heart failure (ABBA) study
Hae-Young Lee, Wook-Jin Chung, Hui-Kyung Jeon, Hong-Seog Seo, Dong-Ju Choi, Eun-Seok Jeon, Jae-Joong Kim, Joon Han Shin, Seok-Min Kang, Sung Cil Lim, Sang-Hong Baek
Korean J Intern Med. 2016;31(2):277-287. Published online February 16, 2016
Background/Aims: We evaluated the association between coding region variants of adrenergic receptor genes and therapeutic effect in patients with congestive heart failure (CHF).
Methods: One hundred patients with stable CHF (left ventricular ejection fraction [LVEF] < 45%) were enrolled. Enrolled ..
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Letter to the editor
Successful transcatheter closure of an inferior sinus venosus atrial septal defect
Hyung Duk Kim, Moon Sung Kim, Kyung-Jin Yun, Sang Mook Bae, Sung-Ho Her, Jae-Hwan Lee
Korean J Intern Med. 2016;31(1):176-178. Published online December 28, 2015
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Cardiology / Review
Breakthrough in heart failure with preserved ejection fraction: are we there yet?
Shir Lynn Lim, Carolyn Su Ping Lam
Korean J Intern Med. 2016;31(1):1-14. Published online December 28, 2015
Heart failure with preserved ejection fraction (HFPEF) is a global health problem of considerable socioeconomic burden. It is projected to worsen with the aging population worldwide. The lack of effective therapies underscores our incomplete understanding of this complex heterogeneous syndrome. A no..
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Cardiology / Original Article
Interatrial septal thickness as a marker of structural and functional remodeling of the left atrium in patients with atrial fibrillation
Hong Euy Lim, Jin Oh Na, Sung Il Im, Cheol Ung Choi, Seong Hwan Kim, Jin Won Kim, Eung Ju Kim, Seong Woo Han, Seung-Woon Rha, Chang Gyu Park, Hong Seog Seo, Dong Joo Oh, Chun Hwang
Korean J Intern Med. 2015;30(6):808-820. Published online October 30, 2015
Background/Aims: There have been reports that interatrial septal (IAS) thickness is increased in patients with atrial fibrillation (AF). This study was performed to investigate whether IAS thickness determined by transthoracic echocardiography (TTE) represents the amount of left atrium (LA) structur..
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Cardiology / Original Article
Prognostic value of hyponatremia in heart failure patients: an analysis of the Clinical Characteristics and Outcomes in the Relation with Serum Sodium Level in Asian Patients Hospitalized for Heart Failure (COAST) study
[editorial]
Byung-Su Yoo, Jin Joo Park, Dong-Ju Choi, Seok-Min Kang, Juey-Jen Hwang, Shing-Jong Lin, Ming-Shien Wen, Jian Zhang, Junbo Ge, on behalf of the COAST investigators
Korean J Intern Med. 2015;30(4):460-470. Published online June 29, 2015
Background/Aims: Hyponatremia is a well-known risk factor for poor outcomes in Western studies of heart failure (HF) patients. We evaluated the predictive value of hyponatremia in hospitalized Asian HF patients.
Methods: The Clinical Characteristics and Outcomes in the Relation with Serum Sodium Le..
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Cardiology / Original Article
Effects of intensive versus mild lipid lowering by statins in patients with ischemic congestive heart failure: Korean Pitavastatin Heart Failure (SAPHIRE) study
Hae-Young Lee, Hyun-Jai Cho, Hee-Yul Kim, Hee-Kyung Jeon, Joon Han Shin, Suk-Min Kang, Sang Hong Baek
Korean J Intern Med. 2014;29(6):754-763. Published online October 31, 2014
Background/Aims: This study was designed to evaluate the dose-effect relationship of statins in patients with ischemic congestive heart failure (CHF), since the role of statins in CHF remains unclear.
Methods: The South koreAn Pitavastatin Heart FaIluRE (SAPHIRE) study was designed to randomize pat..
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Letter to the editor
Acute right heart failure caused by iatrogenic brachiocephalic arteriovenous fistula following orthopedic surgery
Kye Hun Kim, Hyun Ju Yoon, Youngkeun Ahn, Myung Ho Jeong, Jeong Gwan Cho, Jong Chun Park, Jung Chaee Kang
Korean J Intern Med. 2014;29(4):529-531. Published online June 27, 2014
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Cardiology / Original Article
Serum bilirubin as a prognostic marker in patients with acute decompensated heart failure
Jayakrishna Chintanaboina, Matthew S. Haner, Arjinder Sethi, Nimesh Patel, Walid Tanyous, Alexander Lalos, Sameer Pancholy
Korean J Intern Med. 2013;28(3):300-305. Published online May 1, 2013
Background/AimsSeveral prognostic markers for heart failure (HF) have been determined but the importance of liver function tests (LFTs) remains unknown. The aim of this study was to determine the prognostic significance, if any, of abnormal LFTs in acute decompensated HF. <..
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Case Report
A case of papillary fibroelastoma in the left ventricle
Joo Yong Hyun, In Hyun Jung, Hyun Jong Lee, Sook Jin Lee, Jin Seok Kim, Chan Young Na, Young Moo Ro
Korean J Intern Med. 2013;28(1):89-93. Published online December 28, 2012
Cardiac papillary fibroelastoma (CPF) is a rare and benign primary cardiac neoplasm of unknown prevalence. The incidence of CPF in the left ventricle is lower than that in other parts of the heart. A 65-year-old female was referred to our cardiology department for evaluation of a cardiac mass of..
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Nephrology / Original Article
Tissue Doppler-derived E/e' ratio as a parameter for assessing diastolic heart failure and as a predictor of mortality in patients with chronic kidney disease
Min Keun Kim, Biro Kim, Jun Young Lee, Jae Seok Kim, Byoung-Geun Han, Seung Ok Choi, Jae Won Yang
Korean J Intern Med. 2013;28(1):35-44. Published online December 28, 2012
Background/AimsDiastolic dysfunction occurs frequently in patients with chronic kidney disease (CKD) and is associated with heart failure (HF) or mortality. We investigated whether the ratio of early diastolic mitral inflow velocity to early diastolic mitral annulus velocity (..
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Case Report
Angiosarcomas of the Bilateral Breast and Heart: Which One is the Primary Site?
Eun Kyoung Kim, Ik-Soo Park, Byeong Seok Sohn, Jeong Eun Kim, Dae Ho Lee, Sang-We Kim, Cheolwon Suh
Korean J Intern Med. 2012;27(2):224-228. Published online May 31, 2012
A 29-year-old pregnant woman with recurrent pericardial effusion and a cardiac tumor, diagnosed as an angiosarcoma, was treated with surgical resection of the tumor followed by radiotherapy. Immediately after completion of radiotherapy, she developed bilateral breast masses, which were also confi..
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Original Article
Combination of Uric Acid and NT-ProBNP: A More Useful Prognostic Marker for Short-Term Clinical Outcomes in Patients with Acute Heart Failure
Hyoung-Seob Park, Hyungseop Kim, Ji-Hyun Sohn, Hong-Won Shin, Yun-Kyeong Cho, Hyuck-Jun Yoon, Chang-Wook Nam, Seung-Ho Hur, Yoon-Nyun Kim, Kwon-Bae Kim, Hee-Joon Park
Korean J Intern Med. 2010;25(3):253-259. Published online August 31, 2010
Background/AimsIn patients with heart failure (HF), N-terminal prohormone brain natriuretic peptide (NT-ProBNP) is a standard prognostic indicator. In addition, uric acid (UA) was recently established as a prognostic marker for poor outcome in chronic HF. The aim of this stud..
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Original Article
Characteristics of Double-Chambered Right Ventricle in Adult Patients
Yu Jeong Choi, Seung Woo Park
Korean J Intern Med. 2010;25(2):147-153. Published online June 1, 2010
Background/AimsThis study evaluated the clinical features of double-chambered right ventricle (DCRV) in adults. Most cases of DCRV are diagnosed and treated during childhood. Consequently, very few reports include cases in which its clinical characteristics are evident in adul..
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Original Article
Relationship between serum brain natriuretic peptide and heart function in patients with chronic kidney disease
Jae Won Yang, Min Soo Kim, Jae Seok Kim, Jong Myoung Yoo, Seung Tae Han, Bi Ro Kim, Yun Deok Kim, Jeong Wook Choi, Seung Ok Choi, Byoung Geun Han
Korean J Intern Med. 2008;23(4):191-200. Published online December 30, 2008
Background/AimsBrain natriuretic peptide (BNP) levels are known to be elevated in patients with chronic kidney disease (CKD) and normal heart function. Therefore, the present study was performed to examine the effectiveness of BNP level in diagnosing heart failure in patients ..
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Original Article
Ischemia-modified albumin (IMA) is not useful for detecting myocardial ischemia during symptom-limited exercise stress tests
June Hong Kim, Jae Hoon Choi, Hyun-Kook Lee, Woo Hyung Bae, Kook-Jin Chun, Yun Seong Kim, Sang Kwon Lee, Hyung Hoi Kim, Taek Jong Hong, Yong Woo Shin
Korean J Intern Med. 2008;23(3):121-126. Published online September 20, 2008
Background/AimsWe examined the ischemia-modified albumin (IMA) level during exercise in patients with coronary artery disease (CAD). MethodsForty patients with a history of chest pain underwent both symptom-limited treadmill e..
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Original Article
The Epidemiological and Clinical Characteristics of Patients Admitted for Coronary Angiography to Evaluate Ischemic Heart Disease
Jong Seon Park, Hyun Ju Lee, Young Jo Kim, In Whan Seong, Jae Hwan Lee, Chong Jin Kim, Jin Man Cho, Myeong Chan Cho, Jang Whan Bae, Myung Ho Jeong, Young Keun Ahn, Kyoo Rok Han, Jun Hee Lee, Moo Hyun Kim
Korean J Intern Med. 2007;22(2):87-92. Published online June 30, 2007
BackgroundMost of the known risk factors associated with ischemic heart disease are based on studies from Western countries; there is only limited information on Korean populations. This study was designed to analyze age related differences in epidemiologic and clinical charac..
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Case Report
Use of Tadalafil for Treating Pulmonary Arterial Hypertension Secondary to Chronic Obstructive Pulmonary Disease
Hyun-Sook Kim, Jae-Hyeong Park, Seoung Ju Park, Jong Kwan Park, Heung-Bum Lee
Korean J Intern Med. 2007;22(1):37-39. Published online March 31, 2007
Pulmonary arterial hypertension (PAH) secondary to chronic obstructive pulmonary disease (COPD) is incurable and it has an unpredictable survival rate. Two men who suffered from COPD presented with progressive dyspnea and edema, respectively. PAH, as estimated by the peak velocity of tricuspidal ..
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Original Article
Correlation Between Levels of N-terminal Pro-B-Type Natriuretic Peptide and Degrees of Heart Failure
Bong Geun Song, Eun Seok Jeon, Yong Hoon Kim, Min Kyung Kang, Joon Hyung Doh, Phil Ho Kim, Seok Jin Ahn, Hye Lim Oh, Hyun-Joong Kim, Ji Dong Sung, Sang Chol Lee, Hyeon Cheol Gwon, June Soo Kim, Duk-Kyung Kim, Sang Hoon Lee, Kyung Pyo Hong, Jeong Euy Park, Soo Youn Lee, Jong Koo Lee
Korean J Intern Med. 2005;20(1):26-32. Published online March 31, 2005
BackgroundThe N-terminal fragment of pro Brain Natriuretic Peptide (NT-pro BNP) is a neuro-hormone synthesized in the cardiac ventricles in response to increased wall tension. The purpose of this study was to assess the correlation between the NT-pro BNP levels and the New Yor..
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