|
Original Article
A Comparison of Patient Acceptance and Preferences Between CT Colonography and Conventional Colonoscopy in Colorectal Cancer Screening
Hyuk Sang Jung, Dong Kyun Park, Min Ju Kim, Sang Kyun Yu, Kwang An Kwon, Yang Suh Ku, Yu Kyung Kim, Ju Hyun Kim
Korean J Intern Med. 2009;24(1):43-47. Published online March 6, 2009
Background/AimsColorectal cancer, one of the most common cancers in developed countries, is curable when diagnosed at an early stage. However, for better screening, both a test that patients will tolerate and diagnostic accuracy are required. We compared patient experiences an..
|
|
|
Case Report
S-1 Monotherapy as a Neoadjuvant Treatment for Locally Advanced Gastric Cancer
Jong Yul Jung, Sun Young Rha, Joong Bae Ahn, Woo Ick Yang, Sung Hoon Noh, Hyun Cheol Chung, Hei-Cheul Jeung
Korean J Intern Med. 2008;23(1):37-41. Published online March 20, 2008
S-1, a novel oral fluoropyrimidine, is an effective therapeutic agent for gastric cancer. Herein, we report a case with locally advanced gastric cancer that achieved a curative resection after S-1 monotherapy as neoadjuvant treatment. A 68-year-old man was diagnosed with gastric cancer and massiv..
|
|
|
Case Report
Adrenalectomy for Metastatic Disease to the Adrenal Gland from Gastric Cancer: Report of a Case
Young Rok Do, Hong Suk Song, In Ho Kim
Korean J Intern Med. 2007;22(1):18-20. Published online March 31, 2007
Metastases to the adrenal glands are frequently found at autopsy. In practice, adrenal metastases have generally been accepted as evidence of blood-borne systemic disease. So, clinically curable adrenal metastases is a rare malady. The role for surgical resection in adrenal metastases has not bee..
|
|
|
Case Report
Pancreatitis from Metastatic Small Cell Lung Cancer: Successful Treatment with Endoscopic Intrapancreatic Stenting
Jong-Shin Woo, Kwang Ro Joo, Yong Sik Woo, Jae Young Jang, Young Woon Chang, Joung Il Lee, Rin Chang
Korean J Intern Med. 2006;21(4):256-261. Published online December 31, 2006
Lung cancer metastases can occur in almost any organ. However, metastasis of small cell lung cancer to the pancreas is rare. Moreover, not all cases present with clinically diagnosed pancreatitis. We recently treated a patient with small cell lung carcinoma that invaded the pancreatic duct causin..
|
|
|
Case Report
Capecitabine and Oxaliplatin (XELOX) for the Treatment of Patients with Metastatic Gastric Cancer and Severe Liver Dysfunction
Seung Jae Hwang, Jong Won Park, Sehe Dong Lee, Gyong Jung Kim, Cheol Ho Sin, Seung-Hyun Nam, Bong-Seog Kim
Korean J Intern Med. 2006;21(4):252-255. Published online December 31, 2006
Gastric cancer patients with severe liver dysfunction secondary to hepatic metastases have limited treatment options. Most cytotoxic drugs have a narrow therapeutic index. Although both capecitabine and oxaliplatin have been well tolerated as single agents for patients with severe hepatic dysfunc..
|
|
|
Case Report
Photodynamic Therapy in Early Lung Cancer: A Report of Two Cases
Tae Won Jang, Hee Kyoo Kim, Chul Ho Oak, Mann Hong Jung
Korean J Intern Med. 2006;21(3):178-182. Published online September 30, 2006
Photodynamic therapy (PDT) that is based on the science of photochemistry has been recognized as a lung sparing local therapeutic modality that can achieve remarkable responses. It is an alternative treatment for early stage lung cancer patients who have poor lung function or multiple sites of ca..
|
|
|
Original Article
p53 Genetic Polymorphism of Gastric cancer in Korea
Woo Chul Chung, Kang Moon Lee, Bo In Lee, Ji Sung Chun, So Yeon Lee, U-Im Chang, Soo Heon Park, Jin Mo Yang, Kyu Yong Choi, In-Sik Chung
Korean J Intern Med. 2006;21(1):28-32. Published online March 30, 2006
Background/AimsDeletion or functional loss of the p53 tumor suppression gene plays a role in oncogenic transformation. The codon 72 polymorphism on exon 4 in the p53 gene produces variant proteins with either arginine (Arg) or proline (Pro), a..
|
|
|
Original Article
Relationships Between the Expressions of CDX1 and CDX2 mRNA and Clinicopathologic Features in Colorectal Cancers
Gwang Ha Kim, Dong Hyun Lee, Hyung Wook Kim, Jong Yun Cheong, Soo Boon Seo, Jeong Heo, Dae Hwan Kang, Geun Am Song, Mong Cho, Ung Suk Yang, Do Youn Park, Mi Ae Yoo
Korean J Intern Med. 2005;20(4):317-324. Published online December 31, 2005
BackgroundCDX1 and CDX2 are members of the caudal-type homeobox gene family and control the proliferation and differentiation of intestinal mucosal cells. Their expressions are commonly reduced in colorectal cancer, but reports about the relat..
|
|
|
Case Report
Cutaneous Metastases of Pancreatic Carcinoma as a First Clinical Manifestation
Dae Won Jun, Oh Young Lee, Chan Kum Park, Ho Soon Choi, Byung Chul Yoon, Min Ho Lee, Dong Hoo Lee
Korean J Intern Med. 2005;20(3):260-263. Published online September 30, 2005
Cutaneous metastases from pancreatic adenocarcinomas are rare lesions. The most common site of cutaneous metastasis is the umbilicus, and this is also known as the 'Sister Mary Joseph' nodule. A 68-year-old Korean male, who was previously healthy and asymptomatic, was seen in the dermatology depa..
|
|
|
Case Report
A Case of Uterine Cervical Cancer Presenting with Granulocytosis
Heui June Ahn, Yeon Hee Park, Yoon Hwan Chang, Sun Hoo Park, Min-Suk Kim, Baek Yeol Ryoo, Sung Hyun Yang
Korean J Intern Med. 2005;20(3):247-250. Published online September 30, 2005
Granulocytosis occurs in 40% of patients with lung and gastrointestinal cancers, 20% of patients with breast cancer, 30% of patients with brain tumor and ovarian cancer and 10% of patients with renal cell carcinoma. Granulocytosis occurs because of production of G-CSF, GM-CSF and IL-6. Uterine c..
|
|
|
Original Article
Irinotecan, Continuous 5-Fluorouracil, and Low dose of Leucovorin (modified FOLFIRI) as First Line of Therapy in Recurrent or Metastatic Colorectal Cancer
Myung-Ah Lee, Jae-Ho Byun, Byoung-Young Shim, In-Sook Woo, Jin-Hyung Kang, Young Seon Hong, Kyung Shik Lee, Myung Gyu Choi, Suk Kyun Chang, Seong Taek Oh, Sung Il Choi, Doo Suk Lee
Korean J Intern Med. 2005;20(3):205-209. Published online September 30, 2005
BackgroundIrinotecan, in combination with 5-fluorouracil (5-FU) and a high dose of leucovorin (LV), known as FOLFIRI regimen, has shown activity in recurrent or metastatic colorectal cancer. Therefore, we evaluated the efficacy and safety of irinotecan, 5-FU and a low dose of ..
|
|
|
Original Article
Clinicopathologic Significance of Gastric and Intestinal Phenotypic Marker Expression in Gastric Carcinomas
Gwang Ha Kim, Geun Am Song, Do Youn Park, Dong Hyun Lee, Tae Oh Kim, Seong Hun Lee, Jeong Heo, Dae Hwan Kang, Mong Cho
Korean J Intern Med. 2005;20(3):191-197. Published online September 30, 2005
BackgroundIt is well known that both gastric and intestinal phenotypic cell markers are expressed in gastric cancers. This study was aimed at investigating the correlation between gastric and intestinal phenotypic marker expression patterns of tumors and the clinicopathologic ..
|
|
|
Original Article
High Frequency of Microsatellite Instability in Intestinal-type Gastric Cancer in Korean Patients
Won Hyuk Choe, Sun-Young Lee, Jun Haeng Lee, Sang Goon Shim, Young-Ho Kim, Poong-Lyul Rhee, Jong Chul Rhee, Chang-Seok Ki, Jong-Won Kim, Sang Yong Song, Jae J. Kim
Korean J Intern Med. 2005;20(2):116-122. Published online June 30, 2005
BackgroundAlthough there have been some reports on microsatellite alterations in gastric cancer, findings are inconsistent regarding the associations between histological classification and microsatellite instability (MSI). In the present study, we attempted to determine wheth..
|
|
|
Case Report
Non-small Cell Lung Cancer Initially Presenting with Intracardiac Metastasis
Jung Han Kim, Joo Young Jung, Young Iee Park, Sang Ik Hwang, Chull Sung Jung, Sang Hak Lee, Chong Woo Yoo
Korean J Intern Med. 2005;20(1):86-89. Published online March 31, 2005
Intracardiac metastasis as the initial presentation of malignant neoplasm is very rare. We report here on a 64-year-old man with non-small cell lung cancer (NSCLC) initially presenting with intracardiac metastasis which was identified with 18-F fluorodeoxyglucose positron emission tomography (FDG..
|
|
|
Original Article
Prognostic Significance of Immunohistochemical Expression of p53 and Retinoblastoma Gene Protein (pRB) in Curatively Resected Gastric Cancer
Hong Suk Song, In Ho Kim, Soo Sang Sohn, Kun Young Kwon, Won Sik Lee
Korean J Intern Med. 2005;20(1):1-7. Published online March 31, 2005
BackgroundThe aim of this study was to determine the prognostic significance of the expression of p53 and retinoblastoma (Rb) gene products in cases of curatively resected gastric adenocarcinoma, by immunohistochemical analysis. Methods
|
|
|