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Metronomic chemotherapy with capecitabine for metastatic colorectal cancer in very elderly patients
Yun Hwa Jung, Won Jik Lee, Jae Ho Byeon, In Kyu Lee, Chi Wha Han, In Sook Woo
Korean J Intern Med. 2017;32(5):926-929. Published online March 10, 2016
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Lymphoid follicular proctitis resembling rectal carcinoid tumor, confirmed by endoscopic resection
Seungjun Gim, Kang Nyeong Lee, Donghoon Lee, Hye Young Lee, Ki Sul Chang, Oh Young Lee, Ho Soon Choi
Korean J Intern Med. 2017;32(3):548-551. Published online April 18, 2017
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Gastroenterology
Is height a risk factor for colorectal adenoma?
Jeung Hui Pyo, Sung Noh Hong, Byung-Hoon Min, Dong Kyung Chang, Hee Jung Son, Poong-Lyul Rhee, Jae J. Kim, Young-Ho Kim
Korean J Intern Med. 2016;31(4):653-659. Published online December 23, 2015
Background/Aims: Although it is generally known that the risk for all types of cancer increases with adult height, combined and for several common site-specific cancers (including colon and rectal), evidence is limited for adenomas, which are precursors to colorectal cancer. We evaluated the associa..
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Hemato-oncology
Evaluation of treatment response and tissue necrosis as prognostic indicators following neoadjuvant chemoradiotherapy in rectal cancer patients
Ji-Han Jung, Ho Jung An, Hyung-Jin Kim, Jonghoon Lee, Kang-Moon Lee, Sung Hwan Kim, Hyeon-Min Cho, Byoung Yong Shim
Korean J Intern Med. 2016;31(1):134-144. Published online December 28, 2015
Background/Aims: The objective of this study was to assess the prognostic roles of treatment response and tissue necrosis after chemoradiotherapy (CRT) in locally advanced rectal cancer.
Methods: A total of 243 patients with locally advanced rectal cancer who underwent neoadjuvant CRT were included..
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Gastroenterology
Rectal hyposensitivity and functional anorectal outlet obstruction are common entities in patients with functional constipation but are not significantly associated
Tae Hee Lee, Joon Seong Lee, Su Jin Hong, Seong Ran Jeon, Soon Ha Kwon, Wan Jung Kim, Hyun Gun Kim, Won Young Cho, Joo Young Cho, Jin-Oh Kim, Ji Sung Lee
Korean J Intern Med. 2013;28(1):54-61. Published online December 28, 2012
Background/AimsThe causes of functional anorectal outlet obstruction (outlet obstruction) include functional defecation disorder (FDD), rectocele, and rectal intussusception (RI). It is unclear whether outlet obstruction is associated with rectal hyposensitivity (RH) in patien..
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Efficacy and Safety of Hepatic Arterial Infusion of Fluorouracil with Leucovorin as Salvage Treatment for Refractory Liver Metastases from Colorectal Cancer
Hyun Jung Lee, Yoon Soo Lee, Keun-Wook Lee, So Yeon Kim, Chang Jin Yoon, Dong-Yeop Shin, Yun Gyoo Lee, Se Yeon Choi, Sung-Gwon Kang, Sung-Bum Kang, Jee Hyun Kim
Korean J Intern Med. 2011;26(1):82-88. Published online March 2, 2011
Background/AimsLimited options remain for patients with metastatic colorectal cancer (CRC) after failure of standard systemic chemotherapy. Readministration of chemotherapeutic agents by hepatic arterial infusion (HAI) has the rationale of providing higher concentrations of ch..
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Endoscopic and Histopathologic Predictors of Recurrence of Colorectal Adenoma on Lowering the Miss Rate
Jeong-Seon Ji, Kyu-Yong Choi, Won-Chul Lee, Bo-In Lee, Soo-Heon Park, Hwang Choi, Byung-Wook Kim, Hiun-Suk Chae, Yong-Moon Park, Young-Jun Park
Korean J Intern Med. 2009;24(3):196-202. Published online August 26, 2009
Background/AimsAlthough colorectal adenoma is reported to recur frequently, this may result from missing it at baseline. However, few studies of recurrence have considered the miss rate. This study evaluated the recurrence rate prospectively and clinical predictors of recurren..
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A Comparison of Patient Acceptance and Preferences Between CT Colonography and Conventional Colonoscopy in Colorectal Cancer Screening
Hyuk Sang Jung, Dong Kyun Park, Min Ju Kim, Sang Kyun Yu, Kwang An Kwon, Yang Suh Ku, Yu Kyung Kim, Ju Hyun Kim
Korean J Intern Med. 2009;24(1):43-47. Published online March 6, 2009
Background/AimsColorectal cancer, one of the most common cancers in developed countries, is curable when diagnosed at an early stage. However, for better screening, both a test that patients will tolerate and diagnostic accuracy are required. We compared patient experiences an..
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Relationships Between the Expressions of CDX1 and CDX2 mRNA and Clinicopathologic Features in Colorectal Cancers
Gwang Ha Kim, Dong Hyun Lee, Hyung Wook Kim, Jong Yun Cheong, Soo Boon Seo, Jeong Heo, Dae Hwan Kang, Geun Am Song, Mong Cho, Ung Suk Yang, Do Youn Park, Mi Ae Yoo
Korean J Intern Med. 2005;20(4):317-324. Published online December 31, 2005
BackgroundCDX1 and CDX2 are members of the caudal-type homeobox gene family and control the proliferation and differentiation of intestinal mucosal cells. Their expressions are commonly reduced in colorectal cancer, but reports about the relat..
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Irinotecan, Continuous 5-Fluorouracil, and Low dose of Leucovorin (modified FOLFIRI) as First Line of Therapy in Recurrent or Metastatic Colorectal Cancer
Myung-Ah Lee, Jae-Ho Byun, Byoung-Young Shim, In-Sook Woo, Jin-Hyung Kang, Young Seon Hong, Kyung Shik Lee, Myung Gyu Choi, Suk Kyun Chang, Seong Taek Oh, Sung Il Choi, Doo Suk Lee
Korean J Intern Med. 2005;20(3):205-209. Published online September 30, 2005
BackgroundIrinotecan, in combination with 5-fluorouracil (5-FU) and a high dose of leucovorin (LV), known as FOLFIRI regimen, has shown activity in recurrent or metastatic colorectal cancer. Therefore, we evaluated the efficacy and safety of irinotecan, 5-FU and a low dose of ..
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